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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 731079
Species: Homo sapiens
RGD Object: Gene
Symbol: GRIN2B
Name: glutamate ionotropic receptor NMDA type subunit 2B
Acc ID: CHEBI:6809
Term: methamphetamine
Definition: A member of the class of amphetamines in which the amino group of (S)-amphetamine carries a methyl substituent.
Chemical ID: MESH:D008694
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GRIN2Bdecreases expressionISOGrin2b (Rattus norvegicus)6480464CTDMethamphetamine results in decreased expression of GRIN2B mRNAPMID:32035215
GRIN2Bincreases expressionISOGrin2b (Mus musculus)6480464CTDMethamphetamine results in increased expression of GRIN2B proteinPMID:17105907 PMID:32203791
GRIN2Bincreases expressionISOGrin2b (Rattus norvegicus)6480464CTDMethamphetamine results in increased expression of GRIN2B mRNAPMID:18419818
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