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G |
AANAT |
aralkylamine N-acetyltransferase |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of AANAT mRNA Lithium inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of AANAT mRNA] |
CTD |
PMID:19149911 |
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NCBI chr17:76,453,351...76,470,117
Ensembl chr17:76,453,351...76,470,117
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G |
ABCA1 |
ATP binding cassette subfamily A member 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ABCA1 mRNA |
CTD |
PMID:35863504 |
|
NCBI chr 9:104,781,006...104,928,155
Ensembl chr 9:104,781,006...104,928,155
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G |
ABCB1 |
ATP binding cassette subfamily B member 1 |
multiple interactions decreases expression |
ISO |
Melatonin inhibits the reaction [Methamphetamine results in decreased expression of ABCB1 protein] |
CTD |
PMID:28223141 |
|
NCBI chr 7:87,503,017...87,713,295
Ensembl chr 7:87,503,017...87,713,323
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G |
ABCC6 |
ATP binding cassette subfamily C member 6 |
decreases expression multiple interactions |
EXP ISO |
Methamphetamine results in decreased expression of ABCC6 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCC6 mRNA |
CTD |
PMID:19564919 PMID:25290377 |
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NCBI chr16:16,149,565...16,223,494
Ensembl chr16:16,149,565...16,223,522
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G |
ABCD3 |
ATP binding cassette subfamily D member 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of ABCD3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:94,385,131...94,518,663
Ensembl chr 1:94,418,389...94,518,666
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G |
ABCD4 |
ATP binding cassette subfamily D member 4 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of ABCD4 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCD4 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr14:74,285,269...74,302,934
Ensembl chr14:74,285,269...74,303,055
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G |
ABCG1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ABCG1 mRNA |
CTD |
PMID:35863504 |
|
NCBI chr21:42,199,689...42,297,244
Ensembl chr21:42,199,689...42,297,244
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G |
ABCG2 |
ATP binding cassette subfamily G member 2 (JR blood group) |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ABCG2 mRNA Methamphetamine results in decreased expression of ABCG2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628
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G |
ABL1 |
ABL proto-oncogene 1, non-receptor tyrosine kinase |
increases expression |
ISO |
Methamphetamine results in increased expression of ABL1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 9:130,713,043...130,887,675
Ensembl chr 9:130,713,043...130,887,675
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G |
ABLIM1 |
actin binding LIM protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ABLIM1 mRNA |
CTD |
PMID:26307267 PMID:32035215 |
|
NCBI chr10:114,431,110...114,801,373
Ensembl chr10:114,431,112...114,768,061
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G |
ABRA |
actin binding Rho activating protein |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] affects the expression of ABRA mRNA Methamphetamine results in increased expression of ABRA mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:106,759,483...106,770,244
Ensembl chr 8:106,759,483...106,770,244
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G |
ACACB |
acetyl-CoA carboxylase beta |
increases expression |
ISO |
Methamphetamine results in increased expression of ACACB mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:109,111,189...109,268,226
Ensembl chr12:109,116,587...109,268,226
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G |
ACIN1 |
apoptotic chromatin condensation inducer 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ACIN1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr14:23,058,564...23,095,614
Ensembl chr14:23,058,564...23,095,614
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G |
ACO1 |
aconitase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ACO1 protein |
CTD |
PMID:19826936 |
|
NCBI chr 9:32,384,643...32,454,769
Ensembl chr 9:32,384,603...32,454,769
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G |
ACO2 |
aconitase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ACO2 protein |
CTD |
PMID:19826936 |
|
NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273
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G |
ACOT1 |
acyl-CoA thioesterase 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ACOT1 mRNA Methamphetamine results in decreased expression of ACOT1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr14:73,490,933...73,543,796
Ensembl chr14:73,537,143...73,543,796
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G |
ACOX3 |
acyl-CoA oxidase 3, pristanoyl |
increases expression |
ISO |
Methamphetamine results in increased expression of ACOX3 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr 4:8,355,305...8,440,723
Ensembl chr 4:8,366,282...8,440,723
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G |
ACRBP |
acrosin binding protein |
increases expression |
ISO |
Methamphetamine results in increased expression of ACRBP mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:6,638,075...6,647,432
Ensembl chr12:6,638,075...6,647,433
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G |
ACSL5 |
acyl-CoA synthetase long chain family member 5 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of ACSL5 mRNA Lithium inhibits the reaction [Methamphetamine results in increased expression of ACSL5 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr10:112,374,116...112,428,376
Ensembl chr10:112,374,116...112,428,379
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G |
ACSL6 |
acyl-CoA synthetase long chain family member 6 |
affects response to substance |
EXP |
ACSL6 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 5:131,949,973...132,012,213
Ensembl chr 5:131,949,973...132,012,243
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G |
ACTA2 |
actin alpha 2, smooth muscle |
increases expression |
ISO |
Methamphetamine results in increased expression of ACTA2 protein |
CTD |
PMID:35863504 |
|
NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,935,074...88,991,339
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G |
ACTB |
actin beta |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ACTB protein |
CTD |
PMID:19826936 |
|
NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902
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G |
ACTC1 |
actin alpha cardiac muscle 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ACTC1 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,107...34,795,589
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G |
ACTG1 |
actin gamma 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ACTG1 protein |
CTD |
PMID:19826936 |
|
NCBI chr17:81,509,971...81,512,799
Ensembl chr17:81,509,413...81,523,847
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G |
ACVRL1 |
activin A receptor like type 1 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of ACVRL1 promoter |
CTD |
PMID:26307267 |
|
NCBI chr12:51,906,944...51,923,361
Ensembl chr12:51,906,908...51,923,361
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G |
ADAM15 |
ADAM metallopeptidase domain 15 |
increases expression |
ISO |
Methamphetamine results in increased expression of ADAM15 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:155,051,316...155,062,775
Ensembl chr 1:155,050,566...155,062,775
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G |
ADAMTS9 |
ADAM metallopeptidase with thrombospondin type 1 motif 9 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of ADAMTS9 mRNA Methamphetamine results in increased expression of ADAMTS9 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
|
NCBI chr 3:64,515,654...64,688,000
Ensembl chr 3:64,515,654...64,688,000
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G |
ADAMTSL5 |
ADAMTS like 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of ADAMTSL5 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr19:1,505,022...1,513,019
Ensembl chr19:1,505,022...1,513,604
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G |
ADCK2 |
aarF domain containing kinase 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ADCK2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:140,672,945...140,695,110
Ensembl chr 7:140,672,945...140,696,261
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G |
ADCK5 |
aarF domain containing kinase 5 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ADCK5 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:144,373,088...144,393,242
Ensembl chr 8:144,373,101...144,393,242
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G |
ADCY3 |
adenylate cyclase 3 |
multiple interactions decreases expression |
ISO |
(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of ADCY3 mRNA] |
CTD |
PMID:11756511 |
|
NCBI chr 2:24,819,169...24,920,237
Ensembl chr 2:24,819,169...24,920,237
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G |
ADCY4 |
adenylate cyclase 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of ADCY4 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr14:24,318,359...24,335,071
Ensembl chr14:24,318,349...24,335,093
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G |
ADCY6 |
adenylate cyclase 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of ADCY6 mRNA |
CTD |
PMID:26307267 PMID:36914120 |
|
NCBI chr12:48,766,194...48,789,974
Ensembl chr12:48,766,194...48,789,089
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G |
ADD2 |
adducin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ADD2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:70,656,784...70,768,200
Ensembl chr 2:70,607,618...70,768,225
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G |
ADGRF5 |
adhesion G protein-coupled receptor F5 |
increases expression |
ISO |
Methamphetamine results in increased expression of ADGRF5 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 6:46,852,522...46,954,939
Ensembl chr 6:46,852,522...46,954,943
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G |
ADH1C |
alcohol dehydrogenase 1C (class I), gamma polypeptide |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ADH1 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 4:99,336,497...99,352,746
Ensembl chr 4:99,336,497...99,352,746
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G |
ADIPOQ |
adiponectin, C1Q and collagen domain containing |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ADIPOQ mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463
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G |
ADORA1 |
adenosine A1 receptor |
multiple interactions |
ISO |
[8-cyclopentyl-1,3-dimethylxanthine binds to and results in decreased activity of ADORA1 protein] inhibits the reaction [[Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine]; [Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine [N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] promotes the reaction [Methamphetamine results in increased secretion of Dopamine]; [N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] which results in increased susceptibility to Methamphetamine |
CTD |
PMID:7996441 PMID:11043458 |
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NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405
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G |
ADORA2A |
adenosine A2a receptor |
increases response to substance |
EXP |
ADORA2A gene SNP results in increased susceptibility to Methamphetamine |
CTD |
PMID:20799992 |
|
NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357
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G |
ADORA3 |
adenosine A3 receptor |
decreases expression affects response to substance |
ISO |
Methamphetamine results in decreased expression of ADORA3 mRNA ADORA3 affects the susceptibility to Methamphetamine |
CTD |
PMID:19564919 PMID:21867746 |
|
NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
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G |
ADPGK |
ADP dependent glucokinase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ADPGK mRNA |
CTD |
PMID:19564919 |
|
NCBI chr15:72,751,294...72,783,758
Ensembl chr15:72,751,294...72,785,846
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G |
ADRA1B |
adrenoceptor alpha 1B |
affects response to substance |
ISO |
ADRA1B protein affects the susceptibility to Methamphetamine |
CTD |
PMID:12871582 |
|
NCBI chr 5:159,865,086...159,989,205
Ensembl chr 5:159,865,080...159,973,012
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G |
AGBL5 |
AGBL carboxypeptidase 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of AGBL5 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:27,050,364...27,070,618
Ensembl chr 2:27,042,364...27,070,622
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G |
AGMAT |
agmatinase (putative) |
decreases expression |
ISO |
Methamphetamine results in decreased expression of AGMAT mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:15,571,699...15,585,051
Ensembl chr 1:15,571,699...15,585,051
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G |
AGRN |
agrin |
increases expression |
ISO |
Methamphetamine results in increased expression of AGRN mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:1,020,120...1,056,116
Ensembl chr 1:1,020,120...1,056,118
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G |
AGT |
angiotensinogen |
multiple interactions increases expression |
ISO |
candesartan cilexetil promotes the reaction [Methamphetamine results in increased expression of AGT protein] |
CTD |
PMID:33421459 |
|
NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576
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G |
AGTR1 |
angiotensin II receptor type 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of AGTR1A protein |
CTD |
PMID:33421459 |
|
NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008
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G |
AHNAK |
AHNAK nucleoprotein |
increases expression |
ISO |
Methamphetamine results in increased expression of AHNAK mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:62,433,544...62,546,806
Ensembl chr11:62,433,542...62,556,235
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G |
AHSA2P |
activator of HSP90 ATPase homolog 2, pseudogene |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of AHSA2 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of AHSA2 mRNA] |
CTD |
PMID:19564919 |
|
NCBI chr 2:61,177,418...61,188,925
Ensembl chr 2:61,177,418...61,191,203 Ensembl chr 2:61,177,418...61,191,203
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G |
AIF1 |
allograft inflammatory factor 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of AIF1 protein 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]; Minocycline inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein] |
CTD |
PMID:26283213 PMID:29467000 PMID:32278788 PMID:32916201 |
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NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021
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G |
AJAP1 |
adherens junctions associated protein 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of AJAP1 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr 1:4,654,609...4,792,534
Ensembl chr 1:4,654,609...4,792,534
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G |
AK1 |
adenylate kinase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of AK1 protein |
CTD |
PMID:19826936 |
|
NCBI chr 9:127,866,480...127,879,621
Ensembl chr 9:127,866,486...127,877,675
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G |
AK5 |
adenylate kinase 5 |
affects response to substance |
EXP |
AK5 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 1:77,282,019...77,559,966
Ensembl chr 1:77,282,019...77,559,966
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G |
AKAP13 |
A-kinase anchoring protein 13 |
increases expression |
ISO |
Methamphetamine results in increased expression of AKAP13 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr15:85,380,603...85,749,358
Ensembl chr15:85,380,571...85,749,358
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G |
AKAP8L |
A-kinase anchoring protein 8 like |
increases expression |
ISO |
Methamphetamine results in increased expression of AKAP8L mRNA |
CTD |
PMID:26307267 |
|
NCBI chr19:15,380,050...15,418,988
Ensembl chr19:15,380,050...15,419,141
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G |
AKR7A2 |
aldo-keto reductase family 7 member A2 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of AKR7A5 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 1:19,302,708...19,312,146
Ensembl chr 1:19,303,965...19,312,144
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G |
AKT1 |
AKT serine/threonine kinase 1 |
increases response to substance increases phosphorylation decreases phosphorylation increases cleavage multiple interactions affects phosphorylation |
EXP ISO |
AKT1 gene SNP results in increased susceptibility to Methamphetamine Methamphetamine results in increased phosphorylation of AKT1 protein Methamphetamine results in decreased phosphorylation of AKT1 protein Methamphetamine results in increased cleavage of AKT1 protein DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein]; Luteolin inhibits the reaction [Methamphetamine results in increased phosphorylation of AKT1 protein]; Metformin inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased phosphorylation of AKT1 protein]; Methamphetamine results in decreased expression of and results in decreased phosphorylation of AKT1 protein Methamphetamine affects the phosphorylation of AKT1 protein [Rosiglitazone co-treated with Methamphetamine] results in increased phosphorylation of AKT1 protein rosiglitazone inhibits the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:15982448 PMID:26887589 PMID:29981415 PMID:30742852 PMID:31270305 PMID:32035215 PMID:34214594 PMID:35863504 More...
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|
NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
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G |
ALDH1A1 |
aldehyde dehydrogenase 1 family member A1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 9:72,900,671...72,953,053
Ensembl chr 9:72,900,671...73,080,442
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G |
ALDH1A2 |
aldehyde dehydrogenase 1 family member A2 |
increases expression |
EXP |
Methamphetamine results in increased expression of ALDH1A2 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr15:57,953,429...58,065,711
Ensembl chr15:57,953,424...58,497,866
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G |
ALDH2 |
aldehyde dehydrogenase 2 family member |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ALDH2 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532
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G |
ALDOC |
aldolase, fructose-bisphosphate C |
multiple interactions increases expression affects localization |
ISO |
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the localization of ALDOC mRNA] Methamphetamine results in increased expression of ALDOC protein |
CTD |
PMID:18299792 PMID:19826936 |
|
NCBI chr17:28,573,120...28,576,895
Ensembl chr17:28,573,115...28,576,948
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G |
ALG1 |
ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ALG1 mRNA Methamphetamine results in decreased expression of ALG1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr16:5,071,843...5,087,379
Ensembl chr16:5,033,702...5,087,379
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G |
ALS2CL |
ALS2 C-terminal like |
increases expression |
ISO |
Methamphetamine results in increased expression of ALS2CL mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 3:46,668,995...46,693,679
Ensembl chr 3:46,668,995...46,693,704
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G |
AMDHD2 |
amidohydrolase domain containing 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of AMDHD2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr16:2,520,371...2,531,417
Ensembl chr16:2,520,357...2,531,422
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G |
AMPD1 |
adenosine monophosphate deaminase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of AMPD1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:114,673,098...114,695,546
Ensembl chr 1:114,673,090...114,695,618
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G |
AMPD3 |
adenosine monophosphate deaminase 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of AMPD3 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr11:10,450,388...10,507,579
Ensembl chr11:10,308,313...10,507,579
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G |
ANGEL1 |
angel homolog 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ANGEL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:76,786,009...76,812,882
Ensembl chr14:76,786,009...76,826,246
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G |
ANGPT2 |
angiopoietin 2 |
increases expression |
EXP |
Methamphetamine results in increased expression of ANGPT2 mRNA |
CTD |
PMID:25290377 |
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NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409
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G |
ANGPTL2 |
angiopoietin like 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ANGPTL2 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 9:127,087,348...127,122,635
Ensembl chr 9:127,087,348...127,122,635
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G |
ANKRD1 |
ankyrin repeat domain 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ANKRD1 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr10:90,912,096...90,921,087
Ensembl chr10:90,912,096...90,921,087
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G |
ANKRD11 |
ankyrin repeat domain containing 11 |
increases expression |
ISO |
Methamphetamine results in increased expression of ANKRD11 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr16:89,267,630...89,490,561
Ensembl chr16:89,267,630...89,490,561
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G |
ANKRD16 |
ankyrin repeat domain 16 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ANKRD16 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:5,861,616...5,889,893
Ensembl chr10:5,861,616...5,889,906
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G |
ANKRD44 |
ankyrin repeat domain 44 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of ANKRD44 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of ANKRD44 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:196,967,014...197,310,780
Ensembl chr 2:196,967,017...197,311,173
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G |
ANKRD9 |
ankyrin repeat domain 9 |
increases expression |
ISO |
Methamphetamine results in increased expression of ANKRD9 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr14:102,501,767...102,509,776
Ensembl chr14:102,501,767...102,509,799
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G |
ANKS1B |
ankyrin repeat and sterile alpha motif domain containing 1B |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ANKS1B mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:98,734,786...99,984,936
Ensembl chr12:98,726,457...99,984,936
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G |
ANO3 |
anoctamin 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ANO3 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr11:26,188,808...26,663,289
Ensembl chr11:26,188,842...26,663,289
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G |
ANO6 |
anoctamin 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of ANO6 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:45,216,095...45,440,404
Ensembl chr12:45,215,987...45,482,280
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G |
ANXA3 |
annexin A3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ANXA3 protein |
CTD |
PMID:19826936 |
|
NCBI chr 4:78,551,770...78,610,447
Ensembl chr 4:78,551,747...78,610,451
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G |
AOAH |
acyloxyacyl hydrolase |
affects response to substance |
EXP |
AOAH gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 7:36,512,941...36,724,494
Ensembl chr 7:36,512,941...36,724,549
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G |
AP1B1 |
adaptor related protein complex 1 subunit beta 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of AP1B1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr22:29,327,680...29,388,570
Ensembl chr22:29,327,680...29,388,583
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G |
APEX2 |
apurinic/apyrimidinic endodeoxyribonuclease 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of APEX2 mRNA |
CTD |
PMID:19149911 |
|
NCBI chr X:55,000,363...55,009,057
Ensembl chr X:55,000,363...55,009,057
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G |
APLNR |
apelin receptor |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of APLNR mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of APLNR mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:57,233,591...57,237,250
Ensembl chr11:57,233,577...57,237,250
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G |
APOA2 |
apolipoprotein A2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of APOA2 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr 1:161,222,292...161,223,628
Ensembl chr 1:161,222,292...161,223,631
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G |
APOD |
apolipoprotein D |
decreases expression |
ISO |
Methamphetamine results in decreased expression of APOD mRNA |
CTD |
PMID:28619521 |
|
NCBI chr 3:195,568,705...195,583,940
Ensembl chr 3:195,568,705...195,584,033
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G |
APOLD1 |
apolipoprotein L domain containing 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of APOLD1 mRNA Methamphetamine results in increased expression of APOLD1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr12:12,725,917...12,791,466
Ensembl chr12:12,725,917...12,829,975
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G |
APP |
amyloid beta precursor protein |
multiple interactions increases expression increases secretion |
ISO EXP |
Methamphetamine results in increased expression of and results in increased cleavage of APP protein Rosiglitazone inhibits the reaction [Methamphetamine results in increased expression of APP protein] Methamphetamine results in increased secretion of APP protein |
CTD |
PMID:30367931 PMID:31270305 |
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NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128
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G |
APPL2 |
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of APPL2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:105,173,300...105,236,174
Ensembl chr12:105,173,297...105,236,203
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G |
AR |
androgen receptor |
increases expression |
ISO |
Methamphetamine results in increased expression of AR mRNA |
CTD |
PMID:15644446 |
|
NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619
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G |
ARAP3 |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARAP3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 5:141,653,402...141,682,230
Ensembl chr 5:141,653,401...141,682,230
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G |
ARC |
activity regulated cytoskeleton associated protein |
multiple interactions increases expression |
ISO |
CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ARC mRNA] |
CTD |
PMID:11085305 PMID:19564919 PMID:20298714 |
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NCBI chr 8:142,611,049...142,614,479
Ensembl chr 8:142,611,049...142,614,479
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G |
AREG |
amphiregulin |
decreases expression |
ISO |
Methamphetamine results in decreased expression of AREG mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 4:74,445,136...74,455,005
Ensembl chr 4:74,445,136...74,455,005
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G |
ARG2 |
arginase 2 |
multiple interactions increases expression |
ISO |
Lithium inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of ARG2 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708
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G |
ARHGAP29 |
Rho GTPase activating protein 29 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARHGAP29 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:94,168,905...94,314,592
Ensembl chr 1:94,148,988...94,275,068
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G |
ARHGAP9 |
Rho GTPase activating protein 9 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of ARHGAP9 promoter |
CTD |
PMID:26307267 |
|
NCBI chr12:57,472,269...57,488,824
Ensembl chr12:57,472,264...57,488,814
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G |
ARHGDIA |
Rho GDP dissociation inhibitor alpha |
increases expression |
ISO |
Methamphetamine results in increased expression of ARHGDIA protein |
CTD |
PMID:19826936 |
|
NCBI chr17:81,867,721...81,871,337
Ensembl chr17:81,867,721...81,871,378
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G |
ARHGEF1 |
Rho guanine nucleotide exchange factor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARHGEF1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr19:41,883,184...41,930,141
Ensembl chr19:41,883,173...41,930,150
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G |
ARHGEF10 |
Rho guanine nucleotide exchange factor 10 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARHGEF10 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 8:1,823,300...1,958,641
Ensembl chr 8:1,823,926...1,958,641
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G |
ARHGEF15 |
Rho guanine nucleotide exchange factor 15 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARHGEF15 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:8,310,241...8,322,511
Ensembl chr17:8,310,241...8,322,514
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|
G |
ARHGEF2 |
Rho/Rac guanine nucleotide exchange factor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARHGEF2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:155,946,854...155,979,617
Ensembl chr 1:155,946,851...156,007,070
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G |
ARHGEF25 |
Rho guanine nucleotide exchange factor 25 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of ARHGEF25 promoter |
CTD |
PMID:26307267 |
|
NCBI chr12:57,610,116...57,617,245
Ensembl chr12:57,610,180...57,617,245
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G |
ARID1A |
AT-rich interaction domain 1A |
increases methylation increases expression |
ISO |
Methamphetamine results in increased methylation of ARID1A promoter Methamphetamine results in increased expression of ARID1A mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104
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G |
ARIH1 |
ariadne RBR E3 ubiquitin protein ligase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARIH1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987
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G |
ARL14EP |
ADP ribosylation factor like GTPase 14 effector protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ARL14EP mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:30,323,104...30,338,223
Ensembl chr11:30,323,104...30,338,223
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G |
ARL5B |
ADP ribosylation factor like GTPase 5B |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of ARL5B mRNA Methamphetamine results in increased expression of ARL5B mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:18,659,431...18,681,639
Ensembl chr10:18,659,431...18,681,639
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G |
ARNT2 |
aryl hydrocarbon receptor nuclear translocator 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARNT2 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr15:80,404,382...80,597,933
Ensembl chr15:80,404,350...80,597,933
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|
G |
ARRB2 |
arrestin beta 2 |
increases response to substance |
EXP |
ARRB2 gene SNP results in increased susceptibility to Methamphetamine |
CTD |
PMID:17233643 |
|
NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499
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G |
ARRDC2 |
arrestin domain containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ARRDC2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr19:18,001,124...18,014,102
Ensembl chr19:18,001,132...18,014,102
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G |
ASB14 |
ankyrin repeat and SOCS box containing 14 |
increases expression |
ISO |
Methamphetamine results in increased expression of ASB14 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 3:57,268,342...57,292,685
Ensembl chr 3:57,268,342...57,292,685
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G |
ASIC3 |
acid sensing ion channel subunit 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of ASIC3 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr 7:151,048,292...151,052,756
Ensembl chr 7:151,048,292...151,052,756
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G |
ASL |
argininosuccinate lyase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ASL mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:66,075,819...66,093,576
Ensembl chr 7:66,075,800...66,094,697
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G |
ASPM |
assembly factor for spindle microtubules |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ASPM mRNA |
CTD |
PMID:25290377 |
|
NCBI chr 1:197,084,127...197,146,669
Ensembl chr 1:197,084,121...197,146,694
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G |
ASTN2 |
astrotactin 2 |
affects response to substance |
EXP |
ASTN2 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 9:116,423,112...117,415,057
Ensembl chr 9:116,423,112...117,415,070
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G |
ATF3 |
activating transcription factor 3 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of ATF3 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF3 mRNA] Methamphetamine results in increased expression of ATF3 mRNA; Methamphetamine results in increased expression of ATF3 protein |
CTD |
PMID:19564919 |
|
NCBI chr 1:212,565,407...212,620,777
Ensembl chr 1:212,565,334...212,620,777
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G |
ATF4 |
activating transcription factor 4 |
multiple interactions increases expression |
ISO EXP |
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ATF4 protein] ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of ATF4 protein] Methamphetamine results in increased expression of ATF4 mRNA; Methamphetamine results in increased expression of ATF4 protein |
CTD |
PMID:19564919 PMID:27323860 |
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NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683
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G |
ATF6 |
activating transcription factor 6 |
increases expression affects localization multiple interactions increases cleavage |
ISO EXP |
Methamphetamine results in increased expression of ATF6 mRNA; Methamphetamine results in increased expression of ATF6 protein Methamphetamine affects the localization of ATF6 protein ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 protein]; Methamphetamine results in decreased expression of and results in increased cleavage of ATF6 protein; Naltrexone inhibits the reaction [Methamphetamine results in increased cleavage of ATF6 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased cleavage of ATF6 protein] Melatonin inhibits the reaction [Methamphetamine results in increased expression of ATF6 protein] |
CTD |
PMID:19564919 PMID:27323860 PMID:28070110 PMID:34214594 |
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NCBI chr 1:161,766,320...161,964,070
Ensembl chr 1:161,766,298...161,977,574
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G |
ATF6B |
activating transcription factor 6 beta |
multiple interactions increases expression |
ISO |
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of ATF6B protein] |
CTD |
PMID:34214594 |
|
NCBI chr 6:32,115,264...32,128,246
Ensembl chr 6:32,115,264...32,128,253
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G |
ATG14 |
autophagy related 14 |
increases expression |
ISO |
Methamphetamine results in increased expression of ATG14 mRNA |
CTD |
PMID:32676729 |
|
NCBI chr14:55,366,391...55,411,830
Ensembl chr14:55,366,391...55,411,830
|
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G |
ATG16L1 |
autophagy related 16 like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ATG16L1 mRNA |
CTD |
PMID:32676729 |
|
NCBI chr 2:233,251,673...233,295,669
Ensembl chr 2:233,210,051...233,295,674
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G |
ATG2A |
autophagy related 2A |
increases expression |
ISO |
Methamphetamine results in increased expression of ATG2A mRNA |
CTD |
PMID:32676729 |
|
NCBI chr11:64,894,546...64,917,209
Ensembl chr11:64,894,546...64,917,209
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G |
ATG5 |
autophagy related 5 |
multiple interactions increases expression |
ISO |
Luteolin inhibits the reaction [Methamphetamine results in increased expression of ATG5 protein] Methamphetamine results in increased expression of ATG5 mRNA; Methamphetamine results in increased expression of ATG5 protein |
CTD |
PMID:32035215 PMID:32676729 PMID:33359793 PMID:34374793 |
|
NCBI chr 6:106,184,476...106,325,760
Ensembl chr 6:106,045,423...106,325,791
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G |
ATP1A1 |
ATPase Na+/K+ transporting subunit alpha 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ATP1A1 mRNA |
CTD |
PMID:19149911 |
|
NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261
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G |
ATP2A1 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ATP2A1 mRNA |
CTD |
PMID:34374793 |
|
NCBI chr16:28,878,488...28,904,466
Ensembl chr16:28,878,405...28,904,466
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|
G |
ATP2A2 |
ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 |
multiple interactions decreases expression |
ISO |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of ATP2A2 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093
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|
G |
ATP5F1B |
ATP synthase F1 subunit beta |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ATP5F1B protein |
CTD |
PMID:19826936 |
|
NCBI chr12:56,638,175...56,645,984
Ensembl chr12:56,638,175...56,645,984
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G |
ATP5PD |
ATP synthase peripheral stalk subunit d |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ATP5PD protein |
CTD |
PMID:17904249 |
|
NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985
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|
G |
ATP6V0A1 |
ATPase H+ transporting V0 subunit a1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ATP6V0A1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:42,458,878...42,522,579
Ensembl chr17:42,458,844...42,522,582
|
|
G |
ATP6V0E2 |
ATPase H+ transporting V0 subunit e2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ATP6V0E2 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr 7:149,872,964...149,880,713
Ensembl chr 7:149,872,968...149,891,204
|
|
G |
ATP6V1B2 |
ATPase H+ transporting V1 subunit B2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ATP6V1B2 protein |
CTD |
PMID:16181420 PMID:19826936 |
|
NCBI chr 8:20,197,381...20,221,696
Ensembl chr 8:20,197,381...20,226,819
|
|
G |
ATP6V1C2 |
ATPase H+ transporting V1 subunit C2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ATP6V1C2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:10,720,943...10,785,110
Ensembl chr 2:10,721,100...10,785,110
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G |
ATXN2 |
ataxin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ATXN2 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr12:111,452,214...111,599,673
Ensembl chr12:111,443,485...111,599,676
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G |
ATXN2L |
ataxin 2 like |
increases expression |
ISO |
Methamphetamine results in increased expression of ATXN2L mRNA |
CTD |
PMID:26307267 |
|
NCBI chr16:28,822,999...28,837,232
Ensembl chr16:28,822,999...28,837,237
|
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G |
ATXN7L1 |
ataxin 7 like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ATXN7L1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:105,604,772...105,876,599
Ensembl chr 7:105,604,772...105,876,599
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G |
AURKC |
aurora kinase C |
decreases expression |
ISO |
Methamphetamine results in decreased expression of AURKC mRNA |
CTD |
PMID:19564919 |
|
NCBI chr19:57,231,023...57,235,548
Ensembl chr19:57,231,009...57,235,548
|
|
G |
AVP |
arginine vasopressin |
affects expression multiple interactions |
ISO |
Methamphetamine affects the expression of AVP mRNA [Methamphetamine co-treated with SCH 23390] affects the expression of AVP mRNA |
CTD |
PMID:19564919 |
|
NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724
|
|
G |
B3GALT4 |
beta-1,3-galactosyltransferase 4 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of B3GALT4 mRNA Methamphetamine results in decreased expression of B3GALT4 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:33,277,123...33,278,825
Ensembl chr 6:33,277,123...33,284,832
|
|
G |
BACE1 |
beta-secretase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of BACE1 protein |
CTD |
PMID:30367931 |
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NCBI chr11:117,285,698...117,316,256
Ensembl chr11:117,285,232...117,316,259
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G |
BACH2 |
BTB domain and CNC homolog 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of BACH2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:89,926,528...90,296,843
Ensembl chr 6:89,926,528...90,296,843
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G |
BAIAP3 |
BAI1 associated protein 3 |
increases expression |
EXP |
Methamphetamine results in increased expression of BAIAP3 mRNA |
CTD |
PMID:25290377 |
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NCBI chr16:1,333,645...1,349,439
Ensembl chr16:1,333,638...1,349,439
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G |
BAK1 |
BCL2 antagonist/killer 1 |
multiple interactions increases expression |
EXP |
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAK1 protein Methamphetamine results in increased expression of BAK1 protein |
CTD |
PMID:23820845 |
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NCBI chr 6:33,572,552...33,580,276
Ensembl chr 6:33,572,547...33,580,293
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G |
BANP |
BTG3 associated nuclear protein |
increases expression |
ISO |
Methamphetamine results in increased expression of BANP mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:87,949,238...88,077,318
Ensembl chr16:87,949,244...88,077,318
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G |
BARD1 |
BRCA1 associated RING domain 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of BARD1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 2:214,725,646...214,809,683
Ensembl chr 2:214,725,646...214,809,683
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G |
BAX |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Luteolin inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of BAX protein] 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of BAX protein] Methamphetamine results in increased expression of BAX mRNA; Methamphetamine results in increased expression of BAX protein [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BAX protein; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of BAX protein] |
CTD |
PMID:19149911 PMID:23820845 PMID:26307267 PMID:26524635 PMID:26923100 PMID:29467000 PMID:31059759 PMID:31422080 PMID:32035215 PMID:32203791 PMID:34214594 More...
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NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798
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G |
BAZ1B |
bromodomain adjacent to zinc finger domain 1B |
increases expression |
ISO |
Methamphetamine results in increased expression of BAZ1B mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:73,440,406...73,522,293
Ensembl chr 7:73,440,406...73,522,293
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G |
BAZ2A |
bromodomain adjacent to zinc finger domain 2A |
increases expression |
ISO |
Methamphetamine results in increased expression of BAZ2A mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:56,595,596...56,638,318
Ensembl chr12:56,595,596...56,636,816
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G |
BBC3 |
BCL2 binding component 3 |
multiple interactions increases expression |
EXP ISO |
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BBC3 protein; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein] BBC3 protein promotes the reaction [Methamphetamine results in increased expression of NOS2 protein] Methamphetamine results in increased expression of BBC3 protein 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BBC3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BBC3 protein] Methamphetamine results in increased expression of BBC3 mRNA; Methamphetamine results in increased expression of BBC3 protein |
CTD |
PMID:23820845 PMID:26524635 PMID:30394308 PMID:34214594 |
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NCBI chr19:47,220,824...47,232,860
Ensembl chr19:47,220,822...47,232,766
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G |
BCL2 |
BCL2 apoptosis regulator |
affects response to substance increases expression decreases expression multiple interactions |
ISO EXP |
BCL2 protein affects the susceptibility to Methamphetamine Methamphetamine results in increased expression of BCL2 protein Methamphetamine results in decreased expression of BCL2 protein [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2 mRNA; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein] Methamphetamine results in decreased expression of BCL2 mRNA; Methamphetamine results in decreased expression of BCL2 protein 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SOD1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein] 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; bafilomycin A1 promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; GxTX-1E, Plesiophrictus guangxiensis inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Lithium inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Olanzapine inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; STX17 protein inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein] |
CTD |
PMID:11457507 PMID:12050851 PMID:15276877 PMID:19149911 PMID:23820845 PMID:26524635 PMID:26923100 PMID:29297590 PMID:29467000 PMID:31059759 PMID:31422080 PMID:32203791 PMID:32676729 PMID:34214594 PMID:34374793 More...
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NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128
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G |
BCL2L1 |
BCL2 like 1 |
affects expression multiple interactions decreases expression increases methylation increases expression |
ISO EXP |
Methamphetamine affects the expression of BCL2L1 mRNA alternative form EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein] Methamphetamine results in increased methylation of BCL2L1 promoter Methamphetamine results in increased expression of BCL2L1 mRNA Methamphetamine results in decreased expression of BCL2L1 mRNA [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in decreased expression of BCL2L1 mRNA |
CTD |
PMID:10336889 PMID:23820845 PMID:26307267 PMID:31422080 |
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NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989
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G |
BCL2L11 |
BCL2 like 11 |
multiple interactions increases expression |
EXP ISO |
[N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BCL2L11 protein Methamphetamine results in increased expression of BCL2L11 protein 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of BCL2L11 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BCL2L11 protein] |
CTD |
PMID:23820845 PMID:34214594 |
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NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444
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G |
BCL2L15 |
BCL2 like 15 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of BCL2L15 mRNA Methamphetamine results in increased expression of BCL2L15 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:113,876,816...113,887,581
Ensembl chr 1:113,876,816...113,887,581
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G |
BCL2L2 |
BCL2 like 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of BCL2L2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr14:23,306,833...23,311,751
Ensembl chr14:23,298,790...23,311,751
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G |
BCL6 |
BCL6 transcription repressor |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of BCL6 mRNA Methamphetamine results in increased expression of BCL6 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725
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G |
BCL9L |
BCL9 like |
increases expression |
ISO |
Methamphetamine results in increased expression of BCL9L mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:118,896,136...118,925,926
Ensembl chr11:118,893,875...118,925,926
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G |
BDH1 |
3-hydroxybutyrate dehydrogenase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of BDH1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 3:197,509,783...197,573,343
Ensembl chr 3:197,509,783...197,573,323
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G |
BDNF |
brain derived neurotrophic factor |
increases response to substance increases expression multiple interactions decreases expression affects response to substance |
EXP ISO |
BDNF gene SNP results in increased susceptibility to Methamphetamine Methamphetamine results in increased expression of BDNF protein Metformin inhibits the reaction [Methamphetamine results in decreased expression of BDNF protein] BDNF protein affects the susceptibility to Methamphetamine BDNF gene polymorphism affects the susceptibility to Methamphetamine |
CTD |
PMID:15050682 PMID:16039058 PMID:19462300 PMID:20736000 PMID:27373168 PMID:30742852 PMID:34461196 More...
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NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
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G |
BECN1 |
beclin 1 |
multiple interactions increases expression increases phosphorylation |
ISO EXP |
CEBPB protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of BECN1 protein]; Luteolin inhibits the reaction [Methamphetamine results in increased expression of BECN1 protein] NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; sulforaphane inhibits the reaction [Methamphetamine results in increased expression of BECN1 protein] Methamphetamine results in increased phosphorylation of BECN1 protein DDIT4 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein] |
CTD |
PMID:26825372 PMID:31059759 PMID:32035215 PMID:32676729 PMID:33359793 PMID:34374793 PMID:37567421 More...
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NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350
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G |
BHMT2 |
betaine--homocysteine S-methyltransferase 2 |
affects expression multiple interactions |
ISO |
Methamphetamine affects the expression of BHMT2 mRNA [Methamphetamine co-treated with SCH 23390] affects the expression of BHMT2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:79,069,767...79,090,069
Ensembl chr 5:79,069,767...79,090,069
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G |
BID |
BH3 interacting domain death agonist |
increases expression multiple interactions |
EXP |
Methamphetamine results in increased expression of BID mRNA; Methamphetamine results in increased expression of BID protein modified form [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID mRNA; [N-Methyl-3,4-methylenedioxyamphetamine co-treated with Methamphetamine co-treated with 4-methylthioamphetamine co-treated with Dextroamphetamine] results in increased expression of BID protein modified form |
CTD |
PMID:23820845 |
|
NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770
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G |
BIN1 |
bridging integrator 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of BIN1 protein |
CTD |
PMID:19826936 |
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NCBI chr 2:127,048,023...127,107,154
Ensembl chr 2:127,048,027...127,107,288
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G |
BIRC5 |
baculoviral IAP repeat containing 5 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of BIRC5 mRNA |
CTD |
PMID:25290377 |
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NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636
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G |
BMAL1 |
basic helix-loop-helix ARNT like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of BMAL1 mRNA; Methamphetamine results in increased expression of BMAL1 protein |
CTD |
PMID:35863504 |
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NCBI chr11:13,276,652...13,387,266
Ensembl chr11:13,276,652...13,387,266
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G |
BNIP3 |
BCL2 interacting protein 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of BNIP3 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr10:131,967,684...131,981,923
Ensembl chr10:131,967,684...131,981,967
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G |
BRAF |
B-Raf proto-oncogene, serine/threonine kinase |
increases expression |
ISO |
Methamphetamine results in increased expression of BRAF mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
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G |
BRD2 |
bromodomain containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of BRD2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505
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G |
BRD9 |
bromodomain containing 9 |
increases expression |
ISO |
Methamphetamine results in increased expression of BRD9 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 5:863,741...892,801
Ensembl chr 5:850,291...892,801
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G |
BRWD1 |
bromodomain and WD repeat domain containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of BRWD1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr21:39,184,176...39,321,212
Ensembl chr21:39,184,176...39,321,559
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G |
BSPRY |
B-box and SPRY domain containing |
decreases expression |
ISO |
Methamphetamine results in decreased expression of BSPRY mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:113,349,541...113,371,222
Ensembl chr 9:113,349,541...113,371,233
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G |
BST2 |
bone marrow stromal cell antigen 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of BST2 mRNA |
CTD |
PMID:32035215 |
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NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630
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G |
BTAF1 |
B-TFIID TATA-box binding protein associated factor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of BTAF1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:91,923,770...92,031,437
Ensembl chr10:91,923,770...92,031,437
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G |
BTG2 |
BTG anti-proliferation factor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of BTG2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:203,305,519...203,309,602
Ensembl chr 1:203,305,491...203,309,602
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G |
BUB1B |
BUB1 mitotic checkpoint serine/threonine kinase B |
decreases expression |
ISO |
Methamphetamine results in decreased expression of BUB1B mRNA |
CTD |
PMID:28341135 |
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NCBI chr15:40,161,069...40,221,123
Ensembl chr15:40,161,023...40,221,123
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G |
C11orf96 |
chromosome 11 open reading frame 96 |
increases expression |
ISO |
Methamphetamine results in increased expression of C3H11ORF96 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:43,942,637...43,943,878
Ensembl chr11:43,942,637...43,943,878
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G |
C16orf87 |
chromosome 16 open reading frame 87 |
increases expression |
ISO |
Methamphetamine results in increased expression of C19H16ORF87 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:46,796,603...46,831,180
Ensembl chr16:46,796,603...46,831,180
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G |
C16orf89 |
chromosome 16 open reading frame 89 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of C10H16ORF89 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of C10H16ORF89 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:5,042,772...5,065,956
Ensembl chr16:5,044,122...5,066,110
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G |
C1orf210 |
chromosome 1 open reading frame 210 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of C5H1ORF210 mRNA Methamphetamine results in decreased expression of C5H1ORF210 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:43,281,877...43,285,857
Ensembl chr 1:43,281,877...43,285,617
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G |
C1QL1 |
complement C1q like 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of C1QL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:44,959,693...44,968,303
Ensembl chr17:44,959,693...44,968,303
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G |
C1QTNF7 |
C1q and TNF related 7 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of C1QTNF7 mRNA Methamphetamine results in decreased expression of C1QTNF7 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 4:15,339,786...15,446,167
Ensembl chr 4:15,339,818...15,446,167
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G |
C2CD2 |
C2 calcium dependent domain containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of C2CD2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr21:41,885,112...41,954,018
Ensembl chr21:41,885,112...41,954,018
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G |
C3orf33 |
chromosome 3 open reading frame 33 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of C2H3ORF33 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:155,762,617...155,806,278
Ensembl chr 3:155,762,617...155,806,278
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G |
C4BPB |
complement component 4 binding protein beta |
decreases expression |
ISO |
Methamphetamine results in decreased expression of C4BPB mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:207,088,860...207,099,993
Ensembl chr 1:207,088,860...207,099,993
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G |
C8G |
complement C8 gamma chain |
decreases expression |
ISO |
Methamphetamine results in decreased expression of C8G mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:136,945,243...136,946,975
Ensembl chr 9:136,945,185...136,946,975
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G |
C8orf58 |
chromosome 8 open reading frame 58 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of C15H8ORF58 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of C15H8ORF58 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 8:22,599,599...22,604,142
Ensembl chr 8:22,599,599...22,604,150
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G |
CA1 |
carbonic anhydrase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CAR1 protein |
CTD |
PMID:19826936 |
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NCBI chr 8:85,327,608...85,378,113
Ensembl chr 8:85,327,608...85,379,014
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G |
CA11 |
carbonic anhydrase 11 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CAR11 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr19:48,637,946...48,646,187
Ensembl chr19:48,637,946...48,646,187
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G |
CA4 |
carbonic anhydrase 4 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CAR4 mRNA Methamphetamine results in decreased expression of CAR4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:60,149,973...60,179,021
Ensembl chr17:60,149,942...60,170,899
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G |
CA5B |
carbonic anhydrase 5B |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of CAR5B mRNA Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CAR5B mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr X:15,738,270...15,788,411
Ensembl chr X:15,688,830...15,788,411
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G |
CAB39L |
calcium binding protein 39 like |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CAB39L mRNA |
CTD |
PMID:26307267 |
|
NCBI chr13:49,308,650...49,444,064
Ensembl chr13:49,308,650...49,444,064
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G |
CABIN1 |
calcineurin binding protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CABIN1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr22:24,011,304...24,178,628
Ensembl chr22:24,011,192...24,178,628
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G |
CABYR |
calcium binding tyrosine phosphorylation regulated |
increases expression |
ISO |
Methamphetamine results in increased expression of CABYR mRNA |
CTD |
PMID:26307267 |
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NCBI chr18:24,139,062...24,161,600
Ensembl chr18:24,138,987...24,161,600
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G |
CACNA1C |
calcium voltage-gated channel subunit alpha1 C |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of CACNA1C promoter Methamphetamine results in increased expression of CACNA1C mRNA Methamphetamine results in increased expression of CACNA1C mRNA; Methamphetamine results in increased expression of CACNA1C protein |
CTD |
PMID:26307267 PMID:35863504 |
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NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950
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G |
CACNA2D1 |
calcium voltage-gated channel auxiliary subunit alpha2delta 1 |
affects response to substance increases expression multiple interactions |
ISO |
CACNA2D1 protein affects the susceptibility to Methamphetamine Methamphetamine results in increased expression of CACNA2D1 mRNA; Methamphetamine results in increased expression of CACNA2D1 protein [gabapentin binds to and results in decreased activity of CACNA2D1 protein] which results in decreased susceptibility to Methamphetamine; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; gabapentin inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein]; Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; Sulpiride inhibits the reaction [Methamphetamine results in increased expression of CACNA2D1 protein] |
CTD |
PMID:20340177 PMID:21182903 |
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NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956
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G |
CACNB4 |
calcium voltage-gated channel auxiliary subunit beta 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of CACNB4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:151,832,771...152,099,167
Ensembl chr 2:151,832,771...152,099,167
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G |
CACYBP |
calcyclin binding protein |
increases expression |
ISO |
Methamphetamine results in increased expression of CACYBP mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:174,999,435...175,012,027
Ensembl chr 1:174,999,163...175,012,027
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G |
CALB2 |
calbindin 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CALB2 mRNA |
CTD |
PMID:28619521 |
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NCBI chr16:71,358,723...71,390,433
Ensembl chr16:71,358,713...71,390,436
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G |
CALHM2 |
calcium homeostasis modulator family member 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CALHM2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:103,446,786...103,452,370
Ensembl chr10:103,446,786...103,452,402
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G |
CAMTA2 |
calmodulin binding transcription activator 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CAMTA2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:4,967,997...4,987,675
Ensembl chr17:4,967,992...4,987,675
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G |
CAPZB |
capping actin protein of muscle Z-line subunit beta |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CAPZB protein |
CTD |
PMID:16181420 |
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NCBI chr 1:19,338,775...19,485,539
Ensembl chr 1:19,338,775...19,485,539
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G |
CARHSP1 |
calcium regulated heat stable protein 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CARHSP1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:8,852,942...8,869,006
Ensembl chr16:8,852,942...8,869,012
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G |
CARNS1 |
carnosine synthase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CARNS1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:67,415,678...67,425,604
Ensembl chr11:67,414,968...67,425,607
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G |
CASP1 |
caspase 1 |
multiple interactions increases expression increases cleavage |
ISO |
MIR143 mRNA affects the reaction [Methamphetamine results in increased cleavage of CASP1 protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased cleavage of CASP1 protein] Methamphetamine results in increased expression of CASP1 protein |
CTD |
PMID:30394308 PMID:33359793 |
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NCBI chr11:105,025,443...105,036,686
Ensembl chr11:105,025,397...105,035,250
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G |
CASP12 |
caspase 12 (gene/pseudogene) |
increases cleavage decreases expression multiple interactions increases expression |
ISO EXP |
Methamphetamine results in increased cleavage of CASP12 protein Methamphetamine results in decreased expression of CASP12 protein CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP12 protein] Methamphetamine results in increased expression of CASP12 mRNA; Methamphetamine results in increased expression of CASP12 protein CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased cleavage of CASP12 protein] |
CTD |
PMID:28070110 PMID:28619521 PMID:29705343 PMID:32203791 |
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NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670
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G |
CASP2 |
caspase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CASP2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 7:143,288,351...143,307,696
Ensembl chr 7:143,288,215...143,307,696
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G |
CASP3 |
caspase 3 |
multiple interactions increases activity decreases expression increases cleavage decreases cleavage affects cleavage increases expression |
ISO EXP |
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]]; [Methamphetamine co-treated with tin protoporphyrin IX] results in increased cleavage of CASP3 protein; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]; JUN protein affects the reaction [Methamphetamine results in increased activity of CASP3 protein]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein] Methamphetamine results in decreased expression of CASP3 protein Methamphetamine results in decreased cleavage of CASP3 protein ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Methamphetamine results in increased expression of and results in increased cleavage of CASP3 protein; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; SNCA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP3 protein] Methamphetamine affects the cleavage of CASP3 protein 2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; 3-methyladenine promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of CASP3 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Chloroquine promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; GxTX-1E, Plesiophrictus guangxiensis inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; IGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of CASP3 protein]; KN 93 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; Luteolin inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein; Nifedipine inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; SB 203580 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; Sirolimus inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; W 7 inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; wedelolactone inhibits the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein] Methamphetamine results in increased expression of CASP3 mRNA; Methamphetamine results in increased expression of CASP3 protein modified form |
CTD |
PMID:12391261 PMID:19149911 PMID:19442829 PMID:23933405 PMID:25127757 PMID:25523949 PMID:25631491 PMID:26524635 PMID:26825372 PMID:26923100 PMID:27323860 PMID:28341135 PMID:29297590 PMID:29467000 PMID:30450033 PMID:31059759 PMID:31422080 PMID:32035215 PMID:32203791 PMID:32382956 PMID:34214594 PMID:34374793 PMID:36914120 More...
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NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062
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G |
CASP4 |
caspase 4 |
multiple interactions increases expression |
ISO |
CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of and results in increased activity of CASP3 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; Lithium inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of CASP4 mRNA] Methamphetamine results in increased expression of CASP4 mRNA; Methamphetamine results in increased expression of CASP4 protein alternative form |
CTD |
PMID:19149911 PMID:25631491 PMID:28619521 |
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NCBI chr11:104,942,866...104,968,574
Ensembl chr11:104,942,866...104,969,366
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G |
CASP6 |
caspase 6 |
increases cleavage |
ISO |
Methamphetamine results in increased cleavage of CASP6 protein |
CTD |
PMID:32676729 |
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NCBI chr 4:109,664,388...109,709,767
Ensembl chr 4:109,688,622...109,703,583
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G |
CASP9 |
caspase 9 |
multiple interactions increases cleavage |
EXP ISO |
ATF4 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; Methamphetamine results in increased expression of and results in increased cleavage of CASP9 protein; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein] |
CTD |
PMID:27323860 PMID:32676729 |
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NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534
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G |
CAT |
catalase |
decreases expression increases activity multiple interactions decreases activity |
EXP ISO |
Methamphetamine results in decreased expression of CAT protein Methamphetamine results in increased activity of CAT protein ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]]; PRKCD affects the reaction [Methamphetamine results in increased activity of CAT protein] Methamphetamine results in decreased activity of CAT protein Taurine inhibits the reaction [Methamphetamine results in decreased activity of CAT protein] |
CTD |
PMID:12797468 PMID:19948197 PMID:23041169 PMID:24430743 PMID:29467000 |
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NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060
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G |
CAV1 |
caveolin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CAV1 mRNA |
CTD |
PMID:32035215 |
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NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179
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G |
CBLL1 |
Cbl proto-oncogene like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CBLL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 7:107,744,142...107,761,667
Ensembl chr 7:107,743,073...107,761,667
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G |
CBR1 |
carbonyl reductase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CBR1 mRNA |
CTD |
PMID:15644446 |
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NCBI chr21:36,070,024...36,073,164
Ensembl chr21:36,069,941...36,073,166
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G |
CBX1 |
chromobox 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CBX1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:48,070,059...48,101,478
Ensembl chr17:48,070,052...48,101,478
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G |
CBX8 |
chromobox 8 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CBX8 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:79,792,132...79,797,077
Ensembl chr17:79,792,132...79,801,683
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G |
CC2D1B |
coiled-coil and C2 domain containing 1B |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CC2D1B mRNA Methamphetamine results in decreased expression of CC2D1B mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:52,350,597...52,366,205
Ensembl chr 1:52,345,723...52,366,205
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G |
CCDC116 |
coiled-coil domain containing 116 |
increases expression |
ISO |
Methamphetamine results in increased expression of CCDC116 mRNA |
CTD |
PMID:19564919 |
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NCBI chr22:21,632,760...21,637,329
Ensembl chr22:21,632,716...21,637,329
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G |
CCDC117 |
coiled-coil domain containing 117 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of CCDC117 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of CCDC117 mRNA |
CTD |
PMID:19564919 |
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NCBI chr22:28,772,695...28,789,301
Ensembl chr22:28,772,674...28,789,301
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G |
CCDC51 |
coiled-coil domain containing 51 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of CCDC51 promoter |
CTD |
PMID:26307267 |
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NCBI chr 3:48,432,173...48,446,652
Ensembl chr 3:48,432,164...48,440,456
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G |
CCDC57 |
coiled-coil domain containing 57 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CCDC57 mRNA |
CTD |
PMID:32035215 |
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NCBI chr17:82,101,470...82,212,842
Ensembl chr17:82,101,460...82,212,878
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G |
CCHCR1 |
coiled-coil alpha-helical rod protein 1 |
affects response to substance |
EXP |
CCHCR1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 6:31,142,439...31,158,197
Ensembl chr 6:31,142,439...31,158,238
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G |
CCK |
cholecystokinin |
multiple interactions |
ISO |
CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; CCK protein modified form inhibits the reaction [Methamphetamine results in increased phosphorylation of NCF1 protein] CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]] |
CTD |
PMID:27565679 PMID:32916201 |
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NCBI chr 3:42,257,826...42,266,185
Ensembl chr 3:42,257,825...42,266,185
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G |
CCKBR |
cholecystokinin B receptor |
increases expression |
ISO |
Methamphetamine results in increased expression of CCKBR mRNA |
CTD |
PMID:32916201 |
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NCBI chr11:6,259,838...6,272,127
Ensembl chr11:6,259,806...6,272,127
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G |
CCL13 |
C-C motif chemokine ligand 13 |
increases expression |
ISO |
Methamphetamine results in increased expression of CCL12 mRNA |
CTD |
PMID:28341135 |
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NCBI chr17:34,356,480...34,358,610
Ensembl chr17:34,356,480...34,358,610
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G |
CCL15 |
C-C motif chemokine ligand 15 |
increases expression |
ISO |
Methamphetamine results in increased expression of CCL6 mRNA |
CTD |
PMID:36914120 |
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NCBI chr17:35,997,582...36,001,553
Ensembl chr17:35,996,440...36,001,553
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G |
CCL4 |
C-C motif chemokine ligand 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of CCL4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:36,103,827...36,105,614
Ensembl chr17:36,103,827...36,105,621
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G |
CCL5 |
C-C motif chemokine ligand 5 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CCL5 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793
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G |
CCN1 |
cellular communication network factor 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CCN1 mRNA Methamphetamine results in increased expression of CCN1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:85,580,761...85,583,950
Ensembl chr 1:85,580,761...85,584,589
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G |
CCNA1 |
cyclin A1 |
multiple interactions decreases expression |
ISO |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCNA1 mRNA] |
CTD |
PMID:19149911 |
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NCBI chr13:36,431,517...36,442,870
Ensembl chr13:36,431,520...36,442,870
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G |
CCNA2 |
cyclin A2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CCNA2 mRNA; Methamphetamine results in decreased expression of CCNA2 protein |
CTD |
PMID:28341135 |
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NCBI chr 4:121,816,444...121,823,883
Ensembl chr 4:121,816,444...121,823,883
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G |
CCNB1 |
cyclin B1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CCNB1 mRNA; Methamphetamine results in decreased expression of CCNB1 protein |
CTD |
PMID:28341135 |
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NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245
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G |
CCNB2 |
cyclin B2 |
decreases expression |
EXP ISO |
Methamphetamine results in decreased expression of CCNB2 mRNA Methamphetamine results in decreased expression of CCNB2 mRNA; Methamphetamine results in decreased expression of CCNB2 protein |
CTD |
PMID:25290377 PMID:28341135 |
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NCBI chr15:59,105,146...59,125,045
Ensembl chr15:59,105,126...59,125,045
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G |
CCND1 |
cyclin D1 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of CCND1 mRNA Lithium inhibits the reaction [Methamphetamine results in decreased expression of CCND1 mRNA] |
CTD |
PMID:19149911 |
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NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474
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G |
CCNE1 |
cyclin E1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CCNE1 protein |
CTD |
PMID:28341135 |
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NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312
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G |
CCNL1 |
cyclin L1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CCNL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:157,143,121...157,160,147
Ensembl chr 3:157,146,508...157,160,760
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G |
CCNL2 |
cyclin L2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CCNL2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:1,385,711...1,399,335
Ensembl chr 1:1,385,711...1,399,335
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G |
CCR2 |
C-C motif chemokine receptor 2 |
increases response to substance increases methylation increases expression |
ISO |
CCR2 protein results in increased susceptibility to Methamphetamine Methamphetamine results in increased methylation of CCR2 promoter Methamphetamine results in increased expression of CCR2 mRNA |
CTD |
PMID:20624155 |
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NCBI chr 3:46,354,111...46,360,940
Ensembl chr 3:46,353,864...46,360,940
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G |
CCR5 |
C-C motif chemokine receptor 5 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of CCR5 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of CCR5 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206
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G |
CCR7 |
C-C motif chemokine receptor 7 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CCR7 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:40,553,769...40,565,472
Ensembl chr17:40,553,769...40,565,472
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G |
CCT2 |
chaperonin containing TCP1 subunit 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CCT2 protein |
CTD |
PMID:19826936 |
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NCBI chr12:69,585,459...69,601,570
Ensembl chr12:69,585,426...69,601,570
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G |
CCT5 |
chaperonin containing TCP1 subunit 5 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CCT5 protein |
CTD |
PMID:19826936 |
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NCBI chr 5:10,249,921...10,266,412
Ensembl chr 5:10,249,929...10,266,389
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G |
CD151 |
CD151 molecule (Raph blood group) |
increases expression |
ISO |
Methamphetamine results in increased expression of CD151 mRNA |
CTD |
PMID:32035215 |
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NCBI chr11:832,952...838,831
Ensembl chr11:832,887...839,831
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G |
CD177 |
CD177 molecule |
increases expression |
EXP |
Methamphetamine results in increased expression of CD177 mRNA |
CTD |
PMID:25290377 |
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NCBI chr19:43,353,686...43,366,081
Ensembl chr19:43,353,686...43,363,172
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G |
CD36 |
CD36 molecule (CD36 blood group) |
increases expression |
ISO |
Methamphetamine results in increased expression of CD36 mRNA; Methamphetamine results in increased expression of CD36 protein |
CTD |
PMID:35643125 |
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NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277
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G |
CD3D |
CD3 delta subunit of T-cell receptor complex |
increases expression multiple interactions |
ISO EXP |
Methamphetamine results in increased expression of CD3D protein CDK5 protein affects the reaction [Methamphetamine results in increased expression of CD3D protein] |
CTD |
PMID:29705343 |
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NCBI chr11:118,338,954...118,342,705
Ensembl chr11:118,339,075...118,342,705
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G |
CD55 |
CD55 molecule (Cromer blood group) |
affects response to substance |
EXP |
CD55 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 1:207,321,678...207,360,966
Ensembl chr 1:207,321,519...207,386,804
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G |
CDC42EP3 |
CDC42 effector protein 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of CDC42EP3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:37,641,944...37,672,949
Ensembl chr 2:37,641,882...37,738,468
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G |
CDC45 |
cell division cycle 45 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CDC45 mRNA |
CTD |
PMID:25290377 |
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NCBI chr22:19,479,466...19,520,612
Ensembl chr22:19,479,457...19,520,612
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G |
CDCA3 |
cell division cycle associated 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CDCA3 mRNA; Methamphetamine results in decreased expression of CDCA3 protein |
CTD |
PMID:28341135 |
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NCBI chr12:6,844,798...6,851,286
Ensembl chr12:6,844,793...6,851,292
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G |
CDCA7 |
cell division cycle associated 7 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CDCA7 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:173,354,872...173,368,997
Ensembl chr 2:173,354,820...173,368,997
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G |
CDCA8 |
cell division cycle associated 8 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CDCA8 mRNA |
CTD |
PMID:25290377 |
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NCBI chr 1:37,692,516...37,709,719
Ensembl chr 1:37,692,481...37,709,719
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G |
CDH13 |
cadherin 13 |
affects response to substance |
EXP |
CDH13 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr16:82,626,969...83,800,640
Ensembl chr16:82,626,965...83,800,640
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G |
CDH5 |
cadherin 5 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of CDH5 mRNA Luteolin inhibits the reaction [Methamphetamine results in increased expression of CDH5 mRNA] |
CTD |
PMID:32035215 |
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NCBI chr16:66,366,691...66,404,784
Ensembl chr16:66,366,690...66,404,784
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G |
CDHR2 |
cadherin related family member 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CDHR2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:176,542,511...176,595,974
Ensembl chr 5:176,542,511...176,595,974
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G |
CDK1 |
cyclin dependent kinase 1 |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of CDK1 mRNA Methamphetamine results in decreased expression of CDK1 mRNA; Methamphetamine results in decreased expression of CDK1 protein |
CTD |
PMID:15644446 PMID:28341135 |
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NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852
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G |
CDK10 |
cyclin dependent kinase 10 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CDK10 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:89,686,689...89,696,354
Ensembl chr16:89,680,737...89,696,354
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G |
CDK5 |
cyclin dependent kinase 5 |
increases expression increases expression multiple interactions |
EXP ISO |
Methamphetamine results in increased expression of CDK5 protein methamphetamine increases expression of Cdk5 protein in the ventral tegmental area and nucleus accumbens SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of CDK5 protein] CDK5 protein affects the reaction [Methamphetamine results in increased expression of CASP12 protein]; CDK5 protein affects the reaction [Methamphetamine results in increased expression of CD3D protein]; CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of MAPT protein] |
CTD RGD |
PMID:29705343 PMID:32278788 PMID:28782589 |
RGD:401900303 |
NCBI chr 7:151,053,815...151,057,897
Ensembl chr 7:151,053,815...151,057,897
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G |
CDK6 |
cyclin dependent kinase 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of CDK6 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 7:92,604,921...92,836,573
Ensembl chr 7:92,604,921...92,836,573
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G |
CDK9 |
cyclin dependent kinase 9 |
increases expression |
ISO |
Methamphetamine results in increased expression of CDK9 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:127,786,034...127,790,792
Ensembl chr 9:127,785,679...127,790,792
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G |
CDKN1A |
cyclin dependent kinase inhibitor 1A |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CDKN1A mRNA; GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN1A protein] Methamphetamine results in increased expression of CDKN1A mRNA; Methamphetamine results in increased expression of CDKN1A protein |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337
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G |
CDKN2A |
cyclin dependent kinase inhibitor 2A |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of CDKN2A protein GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN2A protein] |
CTD |
PMID:36914120 |
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NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301
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G |
CDKN2B |
cyclin dependent kinase inhibitor 2B |
increases expression |
ISO |
Methamphetamine results in increased expression of CDKN2B mRNA |
CTD |
PMID:15644446 |
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NCBI chr 9:22,002,903...22,009,313
Ensembl chr 9:22,002,903...22,009,305
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G |
CDPF1 |
cysteine rich DPF motif domain containing 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CDPF1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr22:46,244,013...46,250,293
Ensembl chr22:46,244,011...46,250,311
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G |
CDR2 |
cerebellar degeneration related protein 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CDR2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:22,345,936...22,374,619
Ensembl chr16:22,345,936...22,437,165
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G |
CDS2 |
CDP-diacylglycerol synthase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CDS2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr20:5,127,008...5,197,887
Ensembl chr20:5,126,879...5,197,887
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G |
CEBPB |
CCAAT enhancer binding protein beta |
increases expression multiple interactions |
ISO EXP |
Methamphetamine results in increased expression of CEBPB mRNA; Methamphetamine results in increased expression of CEBPB protein CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein] [Methamphetamine co-treated with SCH 23390] results in increased expression of CEBPB mRNA; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; CEBPB protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of DDIT4 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]; CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein] |
CTD |
PMID:19564919 PMID:31059759 |
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NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668
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G |
CELA1 |
chymotrypsin like elastase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CELA1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:51,328,442...51,346,679
Ensembl chr12:51,328,442...51,346,679
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G |
CENPCP1 |
centromere protein C pseudogene 1 |
affects response to substance |
EXP |
CENPCP1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr12:89,499,942...89,503,082
Ensembl chr12:89,500,093...89,502,670
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G |
CENPH |
centromere protein H |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CENPH mRNA |
CTD |
PMID:28341135 |
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NCBI chr 5:69,189,583...69,210,357
Ensembl chr 5:69,189,574...69,210,357
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G |
CENPQ |
centromere protein Q |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CENPQ mRNA |
CTD |
PMID:28341135 |
|
NCBI chr 6:49,463,370...49,493,107
Ensembl chr 6:49,463,370...49,493,107
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G |
CENPW |
centromere protein W |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CENPW mRNA |
CTD |
PMID:28341135 |
|
NCBI chr 6:126,340,115...126,483,320
Ensembl chr 6:126,340,115...126,348,875
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G |
CEP104 |
centrosomal protein 104 |
multiple interactions affects expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CEP104 mRNA Methamphetamine affects the expression of CEP104 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:3,812,086...3,857,211
Ensembl chr 1:3,812,086...3,857,396
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G |
CEP55 |
centrosomal protein 55 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of CEP55 mRNA |
CTD |
PMID:25290377 |
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NCBI chr10:93,496,612...93,529,092
Ensembl chr10:93,496,612...93,529,092
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G |
CEP72 |
centrosomal protein 72 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CEP72 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 5:612,340...676,616
Ensembl chr 5:612,340...667,168
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G |
CEP95 |
centrosomal protein 95 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CEP95 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:64,506,762...64,537,946
Ensembl chr17:64,506,865...64,542,461
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G |
CERT1 |
ceramide transporter 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CERT1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:75,368,486...75,511,981
Ensembl chr 5:75,356,345...75,512,138
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G |
CGGBP1 |
CGG triplet repeat binding protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CGGBP1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:88,051,950...88,149,870
Ensembl chr 3:88,051,944...88,149,885
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G |
CHAC1 |
ChaC glutathione specific gamma-glutamylcyclotransferase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CHAC1 mRNA |
CTD |
PMID:28619521 |
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NCBI chr15:40,953,471...40,956,512
Ensembl chr15:40,952,962...40,956,512
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G |
CHAT |
choline O-acetyltransferase |
decreases activity |
EXP |
Methamphetamine results in decreased activity of CHAT protein |
CTD |
PMID:10089005 |
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NCBI chr10:49,609,095...49,667,942
Ensembl chr10:49,609,095...49,667,942
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G |
CHD4 |
chromodomain helicase DNA binding protein 4 |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of CHD4 promoter Methamphetamine results in increased expression of CHD4 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524
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G |
CHERP |
calcium homeostasis endoplasmic reticulum protein |
increases expression |
ISO |
Methamphetamine results in increased expression of CHERP mRNA |
CTD |
PMID:26307267 |
|
NCBI chr19:16,517,894...16,542,437
Ensembl chr19:16,517,894...16,542,437
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G |
CHKB |
choline kinase beta |
increases expression |
ISO |
Methamphetamine results in increased expression of CHKB mRNA |
CTD |
PMID:26307267 |
|
NCBI chr22:50,578,963...50,582,849
Ensembl chr22:50,578,959...50,601,455
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G |
CHORDC1 |
cysteine and histidine rich domain containing 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CHORDC1 mRNA Methamphetamine results in increased expression of CHORDC1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:90,200,429...90,223,049
Ensembl chr11:90,200,429...90,223,077
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G |
CHRNB1 |
cholinergic receptor nicotinic beta 1 subunit |
increases expression |
ISO |
Methamphetamine results in increased expression of CHRNB1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:7,445,061...7,457,710
Ensembl chr17:7,445,061...7,457,710
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G |
CHRNE |
cholinergic receptor nicotinic epsilon subunit |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CHRNE mRNA Methamphetamine results in increased expression of CHRNE mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:4,897,771...4,908,677
Ensembl chr17:4,897,771...4,934,438
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G |
CHTF18 |
chromosome transmission fidelity factor 18 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CHTF18 mRNA Methamphetamine results in decreased expression of CHTF18 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr16:788,620...798,074
Ensembl chr16:788,046...800,737
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G |
CIAPIN1 |
cytokine induced apoptosis inhibitor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CIAPIN1 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr16:57,428,187...57,447,385
Ensembl chr16:57,428,187...57,447,420
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G |
CIC |
capicua transcriptional repressor |
increases expression |
ISO |
Methamphetamine results in increased expression of CIC mRNA |
CTD |
PMID:26307267 |
|
NCBI chr19:42,268,530...42,295,796
Ensembl chr19:42,268,537...42,295,797
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G |
CIDEA |
cell death inducing DFFA like effector a |
increases expression |
ISO |
Methamphetamine results in increased expression of CIDEA mRNA; Methamphetamine results in increased expression of CIDEA protein |
CTD |
PMID:28341135 |
|
NCBI chr18:12,254,361...12,277,595
Ensembl chr18:12,254,361...12,277,595
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G |
CIRBP |
cold inducible RNA binding protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CIRBP mRNA |
CTD |
PMID:19564919 |
|
NCBI chr19:1,269,332...1,274,880
Ensembl chr19:1,259,384...1,274,880
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G |
CITED2 |
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CITED2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:139,371,807...139,374,648
Ensembl chr 6:139,371,807...139,374,648
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G |
CITED4 |
Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 4 |
multiple interactions increases expression decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CITED4 mRNA Methamphetamine results in increased expression of CITED4 mRNA Methamphetamine results in decreased expression of CITED4 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr 1:40,861,054...40,862,363
Ensembl chr 1:40,861,054...40,862,363
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G |
CKAP2 |
cytoskeleton associated protein 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CKAP2 mRNA |
CTD |
PMID:28341135 |
|
NCBI chr13:52,455,478...52,476,627
Ensembl chr13:52,455,429...52,476,628
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G |
CKB |
creatine kinase B |
increases expression |
ISO |
Methamphetamine results in increased expression of CKB protein |
CTD |
PMID:19826936 |
|
NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833
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G |
CLASRP |
CLK4 associating serine/arginine rich protein |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of SFRS16 mRNA Methamphetamine results in decreased expression of CLASRP mRNA |
CTD |
PMID:26307267 PMID:32035215 |
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NCBI chr19:45,039,045...45,070,956
Ensembl chr19:45,039,045...45,070,956
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G |
CLCN6 |
chloride voltage-gated channel 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of CLCN6 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:11,806,191...11,843,130
Ensembl chr 1:11,806,096...11,848,079
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G |
CLCNKB |
chloride voltage-gated channel Kb |
decreases expression affects methylation |
ISO |
Methamphetamine results in decreased expression of CLCNKB mRNA Methamphetamine affects the methylation of CLCNKB promoter |
CTD |
PMID:26307267 |
|
NCBI chr 1:16,043,782...16,057,326
Ensembl chr 1:16,040,252...16,057,311
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G |
CLDN5 |
claudin 5 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of CLDN5 mRNA [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein] Methamphetamine results in decreased expression of CLDN5 mRNA; Methamphetamine results in decreased expression of CLDN5 protein |
CTD |
PMID:19564919 PMID:35390362 PMID:36720452 |
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NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545
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G |
CLEC4E |
C-type lectin domain family 4 member E |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CLEC4E mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:8,533,275...8,540,905
Ensembl chr12:8,533,305...8,540,905
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G |
CLIC4 |
chloride intracellular channel 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of CLIC4 mRNA |
CTD |
PMID:19149911 |
|
NCBI chr 1:24,745,447...24,844,321
Ensembl chr 1:24,745,382...24,844,321
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G |
CLIP1 |
CAP-Gly domain containing linker protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CLIP1 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
|
NCBI chr12:122,271,469...122,422,956
Ensembl chr12:122,271,432...122,422,669
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G |
CLPX |
caseinolytic mitochondrial matrix peptidase chaperone subunit X |
increases expression |
ISO |
Methamphetamine results in increased expression of CLPX mRNA |
CTD |
PMID:19149911 |
|
NCBI chr15:65,148,219...65,185,342
Ensembl chr15:65,148,219...65,185,342
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G |
CLUH |
clustered mitochondria homolog |
increases expression |
ISO |
Methamphetamine results in increased expression of CLUH mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:2,689,387...2,712,020
Ensembl chr17:2,689,386...2,712,663
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G |
CLVS2 |
clavesin 2 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of CLVS2 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of CLVS2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:122,996,235...123,072,925
Ensembl chr 6:122,996,235...123,072,925
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G |
CMTM3 |
CKLF like MARVEL transmembrane domain containing 3 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of CMTM3 promoter |
CTD |
PMID:26307267 |
|
NCBI chr16:66,603,996...66,613,892
Ensembl chr16:66,603,874...66,613,892
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G |
CMTM8 |
CKLF like MARVEL transmembrane domain containing 8 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CMTM8 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 3:32,238,192...32,370,321
Ensembl chr 3:32,238,679...32,370,321
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G |
CNOT6L |
CCR4-NOT transcription complex subunit 6 like |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of CNOT6L mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of CNOT6L mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 4:77,713,387...77,820,269
Ensembl chr 4:77,713,387...77,819,615
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G |
CNP |
2',3'-cyclic nucleotide 3' phosphodiesterase |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of CNP protein SNCA protein affects the reaction [Methamphetamine results in decreased expression of CNP protein]; TFEB protein inhibits the reaction [Methamphetamine results in decreased expression of CNP protein] |
CTD |
PMID:34562559 |
|
NCBI chr17:41,966,795...41,977,740
Ensembl chr17:41,966,763...41,977,740
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|
G |
CNR1 |
cannabinoid receptor 1 |
affects response to substance |
ISO |
CNR1 protein affects the susceptibility to Methamphetamine |
CTD |
PMID:17953657 |
|
NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347
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G |
CNTFR |
ciliary neurotrophic factor receptor |
increases expression |
ISO |
Methamphetamine results in increased expression of CNTFR mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 9:34,551,433...34,590,852
Ensembl chr 9:34,551,432...34,590,140
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|
G |
CNTN2 |
contactin 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CNTN2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:205,042,949...205,078,289
Ensembl chr 1:205,042,937...205,078,289
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G |
CNTNAP5 |
contactin associated protein family member 5 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CNTNAP5A mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:124,025,287...124,921,219
Ensembl chr 2:124,025,287...124,921,219
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G |
COL10A1 |
collagen type X alpha 1 chain |
increases expression |
ISO |
Methamphetamine results in increased expression of COL10A1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 6:116,118,909...116,217,144
Ensembl chr 6:116,118,909...116,158,747
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G |
COL15A1 |
collagen type XV alpha 1 chain |
decreases expression |
ISO |
Methamphetamine results in decreased expression of COL15A1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 9:98,943,907...99,070,787
Ensembl chr 9:98,943,179...99,070,787
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G |
COL25A1 |
collagen type XXV alpha 1 chain |
decreases expression |
ISO |
Methamphetamine results in decreased expression of COL25A1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 4:108,808,725...109,302,658
Ensembl chr 4:108,808,725...109,302,752
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G |
COL28A1 |
collagen type XXVIII alpha 1 chain |
affects response to substance |
EXP |
COL28A1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 7:7,338,194...7,543,870
Ensembl chr 7:7,356,203...7,535,873
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G |
COL3A1 |
collagen type III alpha 1 chain |
decreases expression |
ISO |
Methamphetamine results in decreased expression of COL3A1 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746
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G |
COL6A2 |
collagen type VI alpha 2 chain |
decreases expression |
ISO |
Methamphetamine results in decreased expression of COL6A2 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr21:46,098,112...46,132,848
Ensembl chr21:46,098,112...46,132,848
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G |
COMT |
catechol-O-methyltransferase |
increases response to substance affects response to substance |
EXP |
COMT gene polymorphism results in increased susceptibility to Methamphetamine COMT gene polymorphism affects the susceptibility to Methamphetamine |
CTD |
PMID:15274053 PMID:19462300 |
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NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975
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G |
COPB2 |
COPI coat complex subunit beta 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of COPB2 mRNA |
CTD |
PMID:32035215 |
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NCBI chr 3:139,357,406...139,389,680
Ensembl chr 3:139,353,946...139,389,736
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G |
COQ10B |
coenzyme Q10B |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of COQ10B mRNA Methamphetamine results in increased expression of COQ10B mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:197,453,552...197,475,310
Ensembl chr 2:197,453,493...197,475,310
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G |
COQ8A |
coenzyme Q8A |
increases expression decreases methylation |
ISO |
Methamphetamine results in increased expression of COQ8A mRNA Methamphetamine results in decreased methylation of COQ8A promoter |
CTD |
PMID:26307267 |
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NCBI chr 1:226,940,294...226,987,544
Ensembl chr 1:226,940,286...226,987,544
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G |
CORIN |
corin, serine peptidase |
increases expression |
ISO |
Methamphetamine results in increased expression of CORIN mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 4:47,594,001...47,838,067
Ensembl chr 4:47,593,999...47,838,106
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G |
CORO6 |
coronin 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of CORO6 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:29,614,762...29,622,912
Ensembl chr17:29,614,756...29,622,912
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G |
COX10 |
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 |
increases expression |
ISO |
Methamphetamine results in increased expression of COX10 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:14,069,504...14,208,677
Ensembl chr17:14,069,490...14,231,736
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G |
CPEB3 |
cytoplasmic polyadenylation element binding protein 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of CPEB3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:92,046,692...92,291,233
Ensembl chr10:92,046,692...92,291,078
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G |
CPLX1 |
complexin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CPLX1 protein |
CTD |
PMID:19826936 |
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NCBI chr 4:784,957...826,129
Ensembl chr 4:784,957...826,129
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G |
CPLX2 |
complexin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CPLX2 protein |
CTD |
PMID:19826936 |
|
NCBI chr 5:175,796,533...175,884,021
Ensembl chr 5:175,796,310...175,884,021
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G |
CPTP |
ceramide-1-phosphate transfer protein |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of CPTP promoter |
CTD |
PMID:26307267 |
|
NCBI chr 1:1,324,802...1,328,896
Ensembl chr 1:1,324,756...1,328,896
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G |
CPZ |
carboxypeptidase Z |
increases expression |
ISO |
Methamphetamine results in increased expression of CPZ mRNA |
CTD |
PMID:15644446 |
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NCBI chr 4:8,592,765...8,619,752
Ensembl chr 4:8,592,660...8,619,759
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G |
CRABP1 |
cellular retinoic acid binding protein 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CRABP1 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr15:78,340,353...78,348,225
Ensembl chr15:78,340,353...78,348,225
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G |
CREB1 |
cAMP responsive element binding protein 1 |
multiple interactions increases activity increases expression |
ISO EXP |
Metformin inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased phosphorylation of CREB1 protein]; Methamphetamine results in decreased expression of and results in decreased phosphorylation of CREB1 protein methamphetamine increases activity of Creb1 protein in the ventral tegmental area and nucleus accumbens 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of CREB1 mRNA]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of CREB1 protein] Methamphetamine results in increased expression of CREB1 mRNA; Methamphetamine results in increased expression of CREB1 protein |
CTD RGD |
PMID:30742852 PMID:33421459 PMID:28782589 |
RGD:401900303 |
NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988
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G |
CREB3L1 |
cAMP responsive element binding protein 3 like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CREB3L1 mRNA |
CTD |
PMID:35863504 |
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NCBI chr11:46,277,662...46,321,409
Ensembl chr11:46,277,662...46,321,409
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G |
CRELD2 |
cysteine rich with EGF like domains 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CRELD2 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr22:49,918,634...49,927,537
Ensembl chr22:49,918,167...49,927,540
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G |
CREM |
cAMP responsive element modulator |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CREM mRNA Methamphetamine results in increased expression of CREM mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:35,126,846...35,212,958
Ensembl chr10:35,126,791...35,212,958
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G |
CRH |
corticotropin releasing hormone |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of CRH mRNA Methamphetamine results in increased expression of CRH mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:66,176,376...66,178,464
Ensembl chr 8:66,176,376...66,178,464
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G |
CRHR1 |
corticotropin releasing hormone receptor 1 |
multiple interactions |
ISO |
[CP 154526 binds to and results in decreased activity of CRHR1 protein] which results in decreased susceptibility to Methamphetamine |
CTD |
PMID:17119930 |
|
NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828
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G |
CRISPLD1 |
cysteine rich secretory protein LCCL domain containing 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CRISPLD1 mRNA Methamphetamine results in decreased expression of CRISPLD1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:74,984,505...75,034,558
Ensembl chr 8:74,984,505...75,034,558
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G |
CRK |
CRK proto-oncogene, adaptor protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CRK protein |
CTD |
PMID:19826936 |
|
NCBI chr17:1,420,693...1,456,232
Ensembl chr17:1,420,689...1,463,162
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G |
CRKL |
CRK like proto-oncogene, adaptor protein |
increases expression |
ISO |
Methamphetamine results in increased expression of CRKL mRNA |
CTD |
PMID:19564919 |
|
NCBI chr22:20,917,407...20,953,747
Ensembl chr22:20,917,407...20,953,747
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G |
CRTC2 |
CREB regulated transcription coactivator 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CRTC2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:153,947,675...153,958,612
Ensembl chr 1:153,947,669...153,958,615
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G |
CRY1 |
cryptochrome circadian regulator 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CRY1 mRNA |
CTD |
PMID:19149911 |
|
NCBI chr12:106,991,364...107,093,549
Ensembl chr12:106,991,364...107,093,549
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G |
CRY2 |
cryptochrome circadian regulator 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CRY2 mRNA |
CTD |
PMID:35863504 |
|
NCBI chr11:45,847,118...45,883,244
Ensembl chr11:45,847,118...45,883,248
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G |
CRYAB |
crystallin alpha B |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of CRYAB mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of CRYAB mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of CRYAB mRNA] |
CTD |
PMID:19564919 |
|
NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722
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G |
CRYM |
crystallin mu |
increases expression |
ISO |
Methamphetamine results in increased expression of CRYM protein |
CTD |
PMID:19826936 |
|
NCBI chr16:21,258,521...21,303,062
Ensembl chr16:21,238,874...21,303,083
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G |
CS |
citrate synthase |
increases expression |
ISO |
Methamphetamine results in increased expression of CS mRNA |
CTD |
PMID:19149911 |
|
NCBI chr12:56,271,699...56,300,330
Ensembl chr12:56,271,699...56,300,391
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G |
CSDC2 |
cold shock domain containing C2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CSDC2 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr22:41,561,010...41,576,666
Ensembl chr22:41,561,010...41,577,741
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G |
CSF1 |
colony stimulating factor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CSF1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992
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G |
CSF1R |
colony stimulating factor 1 receptor |
increases expression |
ISO |
Methamphetamine results in increased expression of CSF1R mRNA |
CTD |
PMID:32035215 |
|
NCBI chr 5:150,053,295...150,113,365
Ensembl chr 5:150,053,291...150,113,372
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G |
CSF2 |
colony stimulating factor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of CSF2 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 5:132,073,789...132,076,170
Ensembl chr 5:132,073,789...132,076,170
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G |
CSMD1 |
CUB and Sushi multiple domains 1 |
affects response to substance |
EXP |
CSMD1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 8:2,935,361...4,994,914
Ensembl chr 8:2,935,353...4,994,972
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G |
CSN1S1 |
casein alpha s1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CSN1S1 mRNA |
CTD |
PMID:28341135 |
|
NCBI chr 4:69,931,068...69,946,574
Ensembl chr 4:69,931,068...69,946,574
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G |
CSRP2 |
cysteine and glycine rich protein 2 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of CSRP2 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of CSRP2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr12:76,858,709...76,879,019
Ensembl chr12:76,858,709...76,879,023
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G |
CST11 |
cystatin 11 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of CST11 promoter |
CTD |
PMID:26307267 |
|
NCBI chr20:23,450,412...23,452,876
Ensembl chr20:23,450,403...23,452,876
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G |
CSTB |
cystatin B |
affects expression |
ISO |
Methamphetamine affects the expression of CSTB protein |
CTD |
PMID:17904249 |
|
NCBI chr21:43,773,950...43,776,308
Ensembl chr21:43,772,511...43,776,330
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G |
CTBP2 |
C-terminal binding protein 2 |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of CTBP2 promoter Methamphetamine results in increased expression of CTBP2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:124,984,317...125,162,463
Ensembl chr10:124,984,317...125,161,170
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G |
CTNNB1 |
catenin beta 1 |
multiple interactions increases expression |
ISO |
Lithium inhibits the reaction [Methamphetamine results in increased expression of CTNNB1 mRNA] |
CTD |
PMID:19149911 PMID:32035215 |
|
NCBI chr 3:41,199,505...41,240,443
Ensembl chr 3:41,194,741...41,260,096
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G |
CTRL |
chymotrypsin like |
increases expression |
ISO |
Methamphetamine results in increased expression of CTRL mRNA |
CTD |
PMID:19564919 |
|
NCBI chr16:67,929,574...67,931,862
Ensembl chr16:67,927,640...67,932,365
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G |
CTSB |
cathepsin B |
increases activity |
ISO |
Methamphetamine results in increased activity of CTSB protein |
CTD |
PMID:34374793 |
|
NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533
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G |
CTSD |
cathepsin D |
affects localization |
ISO |
Methamphetamine affects the localization of CTSD protein |
CTD |
PMID:17105920 |
|
NCBI chr11:1,752,755...1,763,927
Ensembl chr11:1,752,752...1,764,573
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G |
CUBN |
cubilin |
affects response to substance |
EXP |
CUBN gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr10:16,823,966...17,129,811
Ensembl chr10:16,823,966...17,129,811
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G |
CUEDC1 |
CUE domain containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CUEDC1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:57,861,243...57,955,412
Ensembl chr17:57,861,243...57,955,412
|
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G |
CUL2 |
cullin 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CUL2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:35,008,551...35,127,006
Ensembl chr10:35,008,504...35,127,006
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G |
CUL9 |
cullin 9 |
increases expression |
ISO |
Methamphetamine results in increased expression of CUL9 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 6:43,182,196...43,224,587
Ensembl chr 6:43,182,184...43,224,587
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G |
CUX1 |
cut like homeobox 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CUX1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:101,816,007...102,283,958
Ensembl chr 7:101,815,904...102,283,958
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G |
CWC25 |
CWC25 spliceosome associated protein homolog |
increases expression |
ISO |
Methamphetamine results in increased expression of CWC25 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:38,800,441...38,825,321
Ensembl chr17:38,800,441...38,825,355
|
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G |
CX3CR1 |
C-X3-C motif chemokine receptor 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CX3CR1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735
|
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G |
CXCL1 |
C-X-C motif chemokine ligand 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CXCL1 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308
|
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G |
CXCL10 |
C-X-C motif chemokine ligand 10 |
increases expression |
EXP |
Methamphetamine results in increased expression of CXCL10 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497
|
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G |
CXCL12 |
C-X-C motif chemokine ligand 12 |
multiple interactions increases expression |
ISO |
Luteolin inhibits the reaction [Methamphetamine results in increased expression of CXCL12 mRNA] |
CTD |
PMID:32035215 |
|
NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493
|
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G |
CXCL2 |
C-X-C motif chemokine ligand 2 |
increases expression |
EXP ISO |
Methamphetamine results in increased expression of CXCL2 mRNA |
CTD |
PMID:25290377 PMID:36914120 |
|
NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196
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G |
CYB5B |
cytochrome b5 type B |
increases expression |
ISO |
Methamphetamine results in increased expression of CYB5B mRNA |
CTD |
PMID:19149911 |
|
NCBI chr16:69,424,619...69,466,264
Ensembl chr16:69,398,402...69,466,264
|
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G |
CYBB |
cytochrome b-245 beta chain |
multiple interactions |
ISO |
CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein] |
CTD |
PMID:27565679 |
|
NCBI chr X:37,780,059...37,813,461
Ensembl chr X:37,780,018...37,813,461
|
|
G |
CYCS |
cytochrome c, somatic |
increases expression |
ISO |
Methamphetamine results in increased expression of CYCS mRNA |
CTD |
PMID:19149911 |
|
NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260
|
|
G |
CYP11A1 |
cytochrome P450 family 11 subfamily A member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CYP11A1 mRNA |
CTD |
PMID:19149911 |
|
NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646
|
|
G |
CYP1A2 |
cytochrome P450 family 1 subfamily A member 2 |
affects metabolic processing |
EXP |
CYP1A2 protein affects the metabolism of Methamphetamine metabolite |
CTD |
PMID:16038959 |
|
NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607
|
|
G |
CYP27A1 |
cytochrome P450 family 27 subfamily A member 1 |
multiple interactions decreases expression |
ISO |
Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of CYP27A1 mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293
|
|
G |
CYP2D6 |
cytochrome P450 family 2 subfamily D member 6 |
affects response to substance increases metabolic processing |
EXP |
CYP2D4 gene polymorphism affects the susceptibility to Methamphetamine; CYP2D6 protein affects the susceptibility to Methamphetamine CYP2D6 protein results in increased metabolism of Methamphetamine |
CTD |
PMID:18280655 PMID:20727252 PMID:27320963 |
|
NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865
|
|
G |
CYP2E1 |
cytochrome P450 family 2 subfamily E member 1 |
affects metabolic processing |
EXP |
CYP2E1 protein affects the metabolism of Methamphetamine metabolite |
CTD |
PMID:16038959 |
|
NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220
|
|
G |
CYP3A4 |
cytochrome P450 family 3 subfamily A member 4 |
affects metabolic processing multiple interactions |
EXP |
CYP3A4 protein affects the metabolism of Methamphetamine metabolite [Methamphetamine binds to CYP3A4 promoter] which results in increased expression of CYP3A4 mRNA |
CTD |
PMID:12851153 PMID:16038959 |
|
NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248
|
|
G |
CYP7B1 |
cytochrome P450 family 7 subfamily B member 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CYP7B1 mRNA |
CTD |
PMID:35688268 |
|
NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737
|
|
G |
CYTH1 |
cytohesin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of CYTH1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:78,674,048...78,782,273
Ensembl chr17:78,674,048...78,782,297
|
|
G |
CYYR1 |
cysteine and tyrosine rich 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of CYYR1 mRNA Methamphetamine results in decreased expression of CYYR1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr21:26,466,216...26,573,286
Ensembl chr21:26,466,209...26,573,286
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CZIB |
CXXC motif containing zinc binding protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of CZIB mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:53,214,099...53,220,634
Ensembl chr 1:53,214,099...53,220,634
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G |
DAD1 |
defender against cell death 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of DAD1 mRNA SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DAD1 mRNA] |
CTD |
PMID:19564919 |
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NCBI chr14:22,564,907...22,589,224
Ensembl chr14:22,564,907...22,589,224
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G |
DBH |
dopamine beta-hydroxylase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DBH protein |
CTD |
PMID:28661099 |
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NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329
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G |
DBP |
D-box binding PAR bZIP transcription factor |
increases expression decreases expression affects expression |
ISO |
Methamphetamine results in increased expression of DBP mRNA Methamphetamine results in decreased expression of DBP mRNA Methamphetamine affects the expression of DBP mRNA |
CTD |
PMID:26307267 PMID:35863504 PMID:36914120 |
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NCBI chr19:48,630,030...48,637,379
Ensembl chr19:48,630,030...48,637,379
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G |
DCSTAMP |
dendrocyte expressed seven transmembrane protein |
affects response to substance |
EXP |
DCSTAMP gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 8:104,339,796...104,356,689
Ensembl chr 8:104,339,087...104,356,689
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G |
DCTN1 |
dynactin subunit 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DCTN1 mRNA; Methamphetamine results in decreased expression of DCTN1 protein |
CTD |
PMID:34374793 |
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NCBI chr 2:74,361,155...74,391,866
Ensembl chr 2:74,361,154...74,392,087
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G |
DDAH1 |
dimethylarginine dimethylaminohydrolase 1 |
affects expression |
ISO |
Methamphetamine affects the expression of DDAH1 protein |
CTD |
PMID:17904249 |
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NCBI chr 1:85,318,485...85,578,200
Ensembl chr 1:85,318,481...85,578,363
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G |
DDIT3 |
DNA damage inducible transcript 3 |
multiple interactions affects localization increases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; [Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT3 mRNA; DDIT3 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of AKT1 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of FOXO3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BBC3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased expression of BCL2L11 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Methamphetamine promotes the reaction [FOXO3 protein binds to DDIT3 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA] Methamphetamine affects the localization of DDIT3 protein ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF4 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein] Methamphetamine results in increased expression of DDIT3 mRNA; Methamphetamine results in increased expression of DDIT3 protein |
CTD |
PMID:15644446 PMID:19564919 PMID:27323860 PMID:28070110 PMID:28619521 PMID:32203791 PMID:34214594 More...
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NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737
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G |
DDIT4 |
DNA damage inducible transcript 4 |
multiple interactions increases expression increases response to substance |
ISO EXP |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DDIT4 mRNA; CEBPB protein affects the reaction [Methamphetamine results in increased expression of DDIT4 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of CASP3 protein modified form]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of DDIT4 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of PARP1 protein modified form] DDIT4 protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; DDIT4 protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein] Methamphetamine results in increased expression of DDIT4 mRNA; Methamphetamine results in increased expression of DDIT4 protein DDIT4 protein results in increased susceptibility to Methamphetamine |
CTD |
PMID:19564919 PMID:26825372 PMID:31059759 |
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NCBI chr10:72,273,924...72,276,036
Ensembl chr10:72,273,919...72,276,036
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G |
DDT |
D-dopachrome tautomerase |
affects expression |
ISO |
Methamphetamine affects the expression of DDT protein |
CTD |
PMID:17904249 |
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NCBI chr22:23,971,370...23,980,504
Ensembl chr22:23,970,542...23,980,525
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G |
DDX10 |
DEAD-box helicase 10 |
increases expression |
ISO |
Methamphetamine results in increased expression of DDX10 mRNA |
CTD |
PMID:19149911 |
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NCBI chr11:108,665,069...108,940,927
Ensembl chr11:108,665,058...108,940,999
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G |
DDX17 |
DEAD-box helicase 17 |
increases expression |
ISO |
Methamphetamine results in increased expression of DDX17 mRNA |
CTD |
PMID:26307267 |
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NCBI chr22:38,483,438...38,506,311
Ensembl chr22:38,483,438...38,507,660
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G |
DDX21 |
DExD-box helicase 21 |
multiple interactions decreases expression |
ISO |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of DDX21 mRNA] |
CTD |
PMID:19149911 |
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NCBI chr10:68,956,170...68,985,068
Ensembl chr10:68,956,135...68,985,068
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G |
DDX52 |
DExD-box helicase 52 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DDX52 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:37,609,739...37,643,446
Ensembl chr17:37,609,739...37,643,446
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G |
DEAF1 |
DEAF1 transcription factor |
increases expression |
ISO |
Methamphetamine results in increased expression of DEAF1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:644,220...707,083
Ensembl chr11:644,233...707,118
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G |
DENND5A |
DENN domain containing 5A |
increases expression |
ISO |
Methamphetamine results in increased expression of DENND5A mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:9,138,825...9,265,350
Ensembl chr11:9,138,825...9,265,959
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G |
DEPDC1 |
DEP domain containing 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DEPDC1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 1:68,474,152...68,497,082
Ensembl chr 1:68,474,152...68,497,221
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G |
DEPP1 |
DEPP autophagy regulator 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DEPP1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr10:44,976,128...44,978,809
Ensembl chr10:44,970,981...44,978,809
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G |
DGAT2 |
diacylglycerol O-acyltransferase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of DGAT2 mRNA |
CTD |
PMID:35863504 |
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NCBI chr11:75,768,778...75,801,534
Ensembl chr11:75,759,512...75,801,535
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G |
DGKB |
diacylglycerol kinase beta |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DGKB mRNA |
CTD |
PMID:32035215 |
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NCBI chr 7:14,145,049...14,974,858
Ensembl chr 7:14,145,049...14,974,777
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G |
DGKG |
diacylglycerol kinase gamma |
increases expression |
ISO |
Methamphetamine results in increased expression of DGKG mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:186,147,201...186,362,234
Ensembl chr 3:186,105,668...186,362,234
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G |
DGKH |
diacylglycerol kinase eta |
increases expression |
ISO |
Methamphetamine results in increased expression of DGKH mRNA |
CTD |
PMID:26307267 |
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NCBI chr13:42,040,070...42,256,584
Ensembl chr13:42,040,036...42,256,578
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G |
DGKZ |
diacylglycerol kinase zeta |
increases expression |
ISO |
Methamphetamine results in increased expression of DGKZ mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:46,332,926...46,380,554
Ensembl chr11:46,332,905...46,380,554
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G |
DHCR24 |
24-dehydrocholesterol reductase |
increases expression |
ISO |
Methamphetamine results in increased expression of DHCR24 mRNA |
CTD |
PMID:35863504 |
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NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195
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G |
DHX16 |
DEAH-box helicase 16 |
increases expression |
ISO |
Methamphetamine results in increased expression of DHX16 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:30,653,127...30,673,006
Ensembl chr 6:30,653,119...30,673,006
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G |
DIAPH3 |
diaphanous related formin 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DIAPH3 mRNA |
CTD |
PMID:28341135 |
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NCBI chr13:59,665,583...60,163,928
Ensembl chr13:59,665,583...60,163,928
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G |
DICER1 |
dicer 1, ribonuclease III |
increases methylation |
ISO |
Methamphetamine results in increased methylation of DICER1 promoter |
CTD |
PMID:26307267 |
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NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010
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G |
DIO2 |
iodothyronine deiodinase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of DIO2 mRNA |
CTD |
PMID:19149911 |
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NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757
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G |
DIPK1A |
divergent protein kinase domain 1A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DIPK1A mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:92,832,729...92,961,462
Ensembl chr 1:92,832,737...92,961,522
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G |
DIS3 |
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease |
increases expression |
ISO |
Methamphetamine results in increased expression of DIS3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr13:72,752,169...72,781,900
Ensembl chr13:72,752,169...72,782,096
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G |
DIS3L |
DIS3 like exosome 3'-5' exoribonuclease |
increases expression |
ISO |
Methamphetamine results in increased expression of DIS3L mRNA |
CTD |
PMID:26307267 |
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NCBI chr15:66,293,309...66,333,898
Ensembl chr15:66,293,217...66,333,898
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G |
DIS3L2 |
DIS3 like 3'-5' exoribonuclease 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of DIS3L2 mRNA |
CTD |
PMID:32035215 |
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NCBI chr 2:231,961,713...232,344,350
Ensembl chr 2:231,961,245...232,344,350
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G |
DKK1 |
dickkopf WNT signaling pathway inhibitor 1 |
increases expression |
EXP |
Methamphetamine results in increased expression of DKK1 mRNA |
CTD |
PMID:25290377 |
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NCBI chr10:52,314,281...52,317,657
Ensembl chr10:52,314,281...52,318,042
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G |
DLAT |
dihydrolipoamide S-acetyltransferase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DLAT protein |
CTD |
PMID:19826936 |
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NCBI chr11:112,025,408...112,064,404
Ensembl chr11:112,025,033...112,064,404
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G |
DLD |
dihydrolipoamide dehydrogenase |
increases expression |
ISO |
Methamphetamine results in increased expression of DLD protein |
CTD |
PMID:19826936 |
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NCBI chr 7:107,891,107...107,921,198
Ensembl chr 7:107,891,162...107,931,730
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G |
DLG4 |
discs large MAGUK scaffold protein 4 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of DLG4 protein 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of DLG4 protein] |
CTD |
PMID:33421459 PMID:34461196 |
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NCBI chr17:7,187,187...7,220,050
Ensembl chr17:7,187,187...7,219,841
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G |
DLGAP5 |
DLG associated protein 5 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DLGAP5 mRNA |
CTD |
PMID:25290377 |
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NCBI chr14:55,148,135...55,191,585
Ensembl chr14:55,148,112...55,191,608
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G |
DLST |
dihydrolipoamide S-succinyltransferase |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of DLST mRNA; Methamphetamine results in decreased expression of DLST protein Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of DLST mRNA] |
CTD |
PMID:19149911 PMID:19826936 |
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NCBI chr14:74,881,916...74,903,743
Ensembl chr14:74,881,891...74,903,743
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G |
DMD |
dystrophin |
increases expression |
ISO |
Methamphetamine results in increased expression of DMD mRNA |
CTD |
PMID:26307267 |
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NCBI chr X:31,119,222...33,339,388
Ensembl chr X:31,097,677...33,339,609
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G |
DMKN |
dermokine |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of DMKN mRNA Methamphetamine results in decreased expression of DMKN mRNA |
CTD |
PMID:19564919 PMID:32035215 |
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NCBI chr19:35,497,220...35,513,649
Ensembl chr19:35,497,220...35,513,658
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G |
DMPK |
DM1 protein kinase |
increases expression |
ISO |
Methamphetamine results in increased expression of DMPK mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:45,769,709...45,782,490
Ensembl chr19:45,769,709...45,782,552
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G |
DMWD |
DM1 locus, WD repeat containing |
increases expression |
ISO |
Methamphetamine results in increased expression of DMWD mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:45,782,947...45,792,845
Ensembl chr19:45,782,947...45,792,845
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G |
DNAAF2 |
dynein axonemal assembly factor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of DNAAF2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:49,625,174...49,635,244
Ensembl chr14:49,625,174...49,635,244
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G |
DNAH1 |
dynein axonemal heavy chain 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of DNAH1 mRNA Methamphetamine results in decreased expression of DNAH1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:52,310,920...52,400,492
Ensembl chr 3:52,316,319...52,400,492
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G |
DNAH6 |
dynein axonemal heavy chain 6 |
affects expression |
ISO |
Methamphetamine affects the expression of DNAH6 mRNA |
CTD |
PMID:35863504 |
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NCBI chr 2:84,459,572...84,819,589
Ensembl chr 2:84,516,455...84,819,589
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G |
DNAI1 |
dynein axonemal intermediate chain 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of DNAI1 mRNA |
CTD |
PMID:34374793 |
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NCBI chr 9:34,458,805...34,520,984
Ensembl chr 9:34,457,414...34,520,988
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G |
DNAJA1 |
DnaJ heat shock protein family (Hsp40) member A1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJA1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJA1 mRNA] |
CTD |
PMID:19564919 |
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NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907
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G |
DNAJA4 |
DnaJ heat shock protein family (Hsp40) member A4 |
increases expression |
ISO |
Methamphetamine results in increased expression of DNAJA4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr15:78,264,145...78,282,191
Ensembl chr15:78,264,086...78,282,196
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G |
DNAJB1 |
DnaJ heat shock protein family (Hsp40) member B1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB1 mRNA] |
CTD |
PMID:19564919 |
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NCBI chr19:14,514,769...14,560,391
Ensembl chr19:14,514,769...14,560,391
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G |
DNAJB4 |
DnaJ heat shock protein family (Hsp40) member B4 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DNAJB4 mRNA Methamphetamine results in increased expression of DNAJB4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964
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G |
DNAJB5 |
DnaJ heat shock protein family (Hsp40) member B5 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of DNAJB5 mRNA SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJB5 mRNA] |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr 9:34,989,745...34,998,900
Ensembl chr 9:34,989,641...34,998,900
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G |
DNAJC3 |
DnaJ heat shock protein family (Hsp40) member C3 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of DNAJC3 mRNA SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DNAJC3 mRNA] |
CTD |
PMID:19564919 |
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NCBI chr13:95,677,139...95,794,988
Ensembl chr13:95,677,139...95,794,988
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G |
DNAL4 |
dynein axonemal light chain 4 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DNAL4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr22:38,778,508...38,794,143
Ensembl chr22:38,778,508...38,794,198
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G |
DNASE1 |
deoxyribonuclease 1 |
increases expression decreases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of DNASE1 mRNA Methamphetamine results in decreased expression of DNASE1 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of DNASE1 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr16:3,611,760...3,665,461
Ensembl chr16:3,611,728...3,680,143
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G |
DNM1 |
dynamin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of DNM1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:128,203,379...128,255,244
Ensembl chr 9:128,191,655...128,255,248
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G |
DNMT1 |
DNA methyltransferase 1 |
decreases expression increases expression |
ISO |
Methamphetamine results in decreased expression of DNMT1 mRNA Methamphetamine results in increased expression of DNMT1 mRNA |
CTD |
PMID:17254711 |
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NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286
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G |
DOC2GP |
double C2 domain gamma, pseudogene |
increases expression |
ISO |
Methamphetamine results in increased expression of DOC2G mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:67,613,524...67,615,664
Ensembl chr11:67,612,837...67,616,257
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G |
DOCK6 |
dedicator of cytokinesis 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of DOCK6 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:11,199,295...11,262,524
Ensembl chr19:11,199,295...11,262,524
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G |
DOK3 |
docking protein 3 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of DOK3 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of DOK3 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:177,501,904...177,511,100
Ensembl chr 5:177,501,904...177,511,274
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G |
DOLK |
dolichol kinase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DOLK mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 9:128,945,530...128,947,603
Ensembl chr 9:128,945,530...128,947,603
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G |
DPYSL2 |
dihydropyrimidinase like 2 |
affects expression |
ISO |
Methamphetamine affects the expression of DPYSL2 protein |
CTD |
PMID:19826936 |
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NCBI chr 8:26,514,031...26,658,175
Ensembl chr 8:26,514,031...26,658,178
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G |
DPYSL3 |
dihydropyrimidinase like 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DPYSL3 protein |
CTD |
PMID:19826936 |
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NCBI chr 5:147,390,808...147,510,068
Ensembl chr 5:147,390,808...147,510,068
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G |
DPYSL5 |
dihydropyrimidinase like 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of DPYSL5 protein |
CTD |
PMID:19826936 |
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NCBI chr 2:26,847,995...26,950,351
Ensembl chr 2:26,847,747...26,950,351
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DRD1 |
dopamine receptor D1 |
increases expression decreases expression multiple interactions affects activity increases response to substance |
EXP ISO |
Methamphetamine results in increased expression of DRD1 protein Methamphetamine results in decreased expression of DRD1 protein 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the activity of DRD1 protein]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; Methamphetamine inhibits the reaction [SCH 23390 binds to DRD1 protein] DRD1 protein results in increased susceptibility to Methamphetamine [SCH 23390 binds to and results in decreased activity of DRD1 protein] which results in decreased susceptibility to Methamphetamine; bisphenol A promotes the reaction [DRD1 protein results in increased susceptibility to Methamphetamine]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD1 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein] |
CTD |
PMID:2891082 PMID:11126397 PMID:11701771 PMID:12617968 PMID:18363855 PMID:18489579 PMID:19444617 PMID:19733155 PMID:20340177 More...
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NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182
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DRD2 |
dopamine receptor D2 |
increases response to substance decreases expression multiple interactions increases activity affects activity |
EXP ISO |
DRD2 gene polymorphism results in increased susceptibility to Methamphetamine Methamphetamine results in decreased expression of DRD2 protein [Sulpiride binds to and results in decreased activity of DRD2 protein] which results in decreased susceptibility to Methamphetamine; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 mRNA]; DRD2 protein affects the reaction [Methamphetamine results in increased expression of CACNA2D1 protein] Methamphetamine results in increased activity of DRD2 protein Methamphetamine affects the activity of DRD2 protein DRD2 gene results in increased susceptibility to Methamphetamine 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the activity of DRD2 protein]; [Aripiprazole binds to and results in increased activity of DRD2 protein] which results in increased susceptibility to Methamphetamine; Methamphetamine inhibits the reaction [Sulpiride binds to DRD2 protein] |
CTD |
PMID:2891082 PMID:11126397 PMID:11729018 PMID:17327886 PMID:18363855 PMID:18489579 PMID:18555060 PMID:19046384 PMID:19940168 PMID:20340177 More...
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NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691
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DRD3 |
dopamine receptor D3 |
decreases expression increases activity |
EXP ISO |
Methamphetamine results in decreased expression of DRD3 protein Methamphetamine results in increased activity of DRD3 protein |
CTD |
PMID:19046384 PMID:19940168 |
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NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407
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G |
DRD4 |
dopamine receptor D4 |
affects response to substance multiple interactions increases response to substance |
EXP ISO |
DRD4 gene polymorphism affects the susceptibility to Methamphetamine [NRA 0160 binds to and results in decreased activity of DRD4 protein] which results in decreased susceptibility to Methamphetamine DRD4 gene polymorphism results in increased susceptibility to Methamphetamine |
CTD |
PMID:10579464 PMID:15274053 PMID:19462300 |
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NCBI chr11:637,269...640,706
Ensembl chr11:637,269...640,706
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DSP |
desmoplakin |
increases expression |
ISO |
Methamphetamine results in increased expression of DSP mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:7,541,671...7,586,714
Ensembl chr 6:7,541,338...7,586,714
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DSPP |
dentin sialophosphoprotein |
increases expression |
ISO |
Methamphetamine results in increased expression of DSPP mRNA |
CTD |
PMID:15644446 |
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NCBI chr 4:87,608,529...87,616,873
Ensembl chr 4:87,608,529...87,616,873
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DST |
dystonin |
increases expression |
ISO |
Methamphetamine results in increased expression of DST mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:56,457,996...56,954,830
Ensembl chr 6:56,457,987...56,954,830
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DTL |
denticleless E3 ubiquitin protein ligase homolog |
decreases expression |
EXP |
Methamphetamine results in decreased expression of DTL mRNA |
CTD |
PMID:25290377 |
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NCBI chr 1:212,035,748...212,105,013
Ensembl chr 1:212,035,553...212,107,400
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DTX3 |
deltex E3 ubiquitin ligase 3 |
increases expression increases methylation |
ISO |
Methamphetamine results in increased expression of DTX3 mRNA Methamphetamine results in increased methylation of DTX3 promoter |
CTD |
PMID:26307267 |
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NCBI chr12:57,604,824...57,609,802
Ensembl chr12:57,604,622...57,609,804
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G |
DUSP1 |
dual specificity phosphatase 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP1 mRNA; [SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA]; Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP1 mRNA] |
CTD |
PMID:11701771 PMID:19564919 PMID:26307267 |
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NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195
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DUSP11 |
dual specificity phosphatase 11 |
increases expression |
ISO |
Methamphetamine results in increased expression of DUSP11 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:73,762,213...73,780,149
Ensembl chr 2:73,761,782...73,780,132
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DUSP14 |
dual specificity phosphatase 14 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of DUSP14 mRNA Methamphetamine results in increased expression of DUSP14 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:37,488,566...37,513,498
Ensembl chr17:37,489,891...37,513,501
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DUSP5 |
dual specificity phosphatase 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of DUSP5 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533
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DUSP6 |
dual specificity phosphatase 6 |
multiple interactions increases expression |
ISO |
[SCH 23390 binds to and results in decreased activity of DRD1 protein] inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA]; Dizocilpine Maleate inhibits the reaction [Methamphetamine results in increased expression of DUSP6 mRNA] |
CTD |
PMID:11701771 |
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NCBI chr12:89,347,235...89,352,501
Ensembl chr12:89,347,235...89,352,501
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DUT |
deoxyuridine triphosphatase |
increases expression |
ISO |
Methamphetamine results in increased expression of DUT mRNA |
CTD |
PMID:19149911 |
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NCBI chr15:48,331,095...48,343,373
Ensembl chr15:48,331,011...48,343,373
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G |
DUX4 |
double homeobox 4 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of DUXBL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:190,173,774...190,185,911
Ensembl chr 4:190,173,774...190,185,942
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DYDC2 |
DPY30 domain containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of DYDC2 mRNA |
CTD |
PMID:28341135 |
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NCBI chr10:80,344,745...80,368,073
Ensembl chr10:80,344,745...80,368,073
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DYSF |
dysferlin |
increases expression |
ISO |
Methamphetamine results in increased expression of DYSF mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:71,453,561...71,686,763
Ensembl chr 2:71,453,561...71,686,763
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EBI3 |
Epstein-Barr virus induced 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of EBI3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:4,229,523...4,237,528
Ensembl chr19:4,229,523...4,237,528
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ECHDC2 |
enoyl-CoA hydratase domain containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ECHDC2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:52,895,910...52,921,774
Ensembl chr 1:52,895,910...52,927,212
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G |
ECHDC3 |
enoyl-CoA hydratase domain containing 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ECHDC3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:11,742,382...11,764,070
Ensembl chr10:11,742,366...11,764,070
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ECT2 |
epithelial cell transforming 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ECT2 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 3:172,750,726...172,829,265
Ensembl chr 3:172,750,682...172,821,474
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EDC4 |
enhancer of mRNA decapping 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of EDC4 mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:67,873,052...67,884,499
Ensembl chr16:67,873,052...67,884,499
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EDN3 |
endothelin 3 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of EDN3 mRNA GATA4 protein affects the reaction [Methamphetamine results in increased expression of EDN3 mRNA] |
CTD |
PMID:36914120 |
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NCBI chr20:59,300,611...59,325,992
Ensembl chr20:59,300,443...59,325,992
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G |
EEF2K |
eukaryotic elongation factor 2 kinase |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of EEF2K promoter |
CTD |
PMID:26307267 |
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NCBI chr16:22,206,278...22,288,738
Ensembl chr16:22,206,278...22,288,738
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EFNB1 |
ephrin B1 |
increases expression |
ISO |
Methamphetamine results in increased expression of EFNB1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr X:68,829,021...68,842,160
Ensembl chr X:68,829,021...68,842,160
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G |
EGFL7 |
EGF like domain multiple 7 |
multiple interactions increases expression decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFL7 mRNA Methamphetamine results in increased expression of EGFL7 mRNA Methamphetamine results in decreased expression of EGFL7 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr 9:136,658,856...136,672,678
Ensembl chr 9:136,658,856...136,672,678
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EGFLAM |
EGF like, fibronectin type III and laminin G domains |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of EGFLAM mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of EGFLAM mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:38,258,559...38,465,480
Ensembl chr 5:38,258,409...38,465,480
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G |
EGLN3 |
egl-9 family hypoxia inducible factor 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of EGLN3 mRNA |
CTD |
PMID:36914120 |
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NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774
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EGR1 |
early growth response 1 |
multiple interactions increases expression |
ISO |
CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA] Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]] |
CTD |
PMID:11754491 PMID:15644446 PMID:19564919 PMID:20184921 PMID:20298714 |
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NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303
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EGR2 |
early growth response 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of EGR2 mRNA |
CTD |
PMID:15644446 PMID:19564919 |
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NCBI chr10:62,811,996...62,819,167
Ensembl chr10:62,811,996...62,819,167
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G |
EGR4 |
early growth response 4 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of EGR4 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of EGR4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:73,290,929...73,293,548
Ensembl chr 2:73,290,929...73,293,701
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EHBP1L1 |
EH domain binding protein 1 like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of EHBP1L1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:65,576,053...65,592,650
Ensembl chr11:65,576,046...65,592,650
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EHMT2 |
euchromatic histone lysine methyltransferase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of EHMT2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:31,879,759...31,897,698
Ensembl chr 6:31,879,759...31,897,698
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G |
EIF2AK3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions increases phosphorylation increases expression |
ISO EXP |
CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of EIF2AK3 protein modified form] CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of ATF4 protein]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; EIF2AK3 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein] |
CTD |
PMID:27323860 PMID:28070110 PMID:29705343 |
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NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518
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EIF2S1 |
eukaryotic translation initiation factor 2 subunit alpha |
increases phosphorylation multiple interactions |
ISO |
Methamphetamine results in increased phosphorylation of EIF2S1 protein 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2S1 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2S1 protein] |
CTD |
PMID:28070110 PMID:34214594 |
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NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516
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G |
EIF4EBP1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions |
EXP |
Methamphetamine inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein] |
CTD |
PMID:19054297 |
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NCBI chr 8:38,030,534...38,060,365
Ensembl chr 8:38,030,534...38,060,365
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EIF4G2 |
eukaryotic translation initiation factor 4 gamma 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of EIF4G2 mRNA |
CTD |
PMID:10336889 |
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NCBI chr11:10,797,046...10,808,926
Ensembl chr11:10,797,050...10,808,940
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ELP1 |
elongator acetyltransferase complex subunit 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ELP1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:108,867,517...108,934,124
Ensembl chr 9:108,866,898...108,934,328
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EML1 |
EMAP like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of EML1 mRNA |
CTD |
PMID:32035215 |
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NCBI chr14:99,737,722...99,942,060
Ensembl chr14:99,737,693...99,942,060
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EML2 |
EMAP like 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of EML2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:45,609,400...45,645,629
Ensembl chr19:45,606,994...45,645,602
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EMSY |
EMSY transcriptional repressor, BRCA2 interacting |
increases expression |
ISO |
Methamphetamine results in increased expression of EMSY mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:76,445,018...76,553,031
Ensembl chr11:76,444,923...76,553,031
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ENO1 |
enolase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ENO1 protein |
CTD |
PMID:19826936 |
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NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190
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ENO2 |
enolase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ENO2 protein |
CTD |
PMID:19826936 |
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NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698
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ENPP1 |
ectonucleotide pyrophosphatase/phosphodiesterase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ENPP1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155
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ENPP6 |
ectonucleotide pyrophosphatase/phosphodiesterase 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ENPP6 mRNA |
CTD |
PMID:28619521 |
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NCBI chr 4:184,088,706...184,217,873
Ensembl chr 4:184,088,706...184,221,230
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EP400 |
E1A binding protein p400 |
increases expression |
ISO |
Methamphetamine results in increased expression of EP400 mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:131,949,942...132,080,460
Ensembl chr12:131,949,942...132,080,460
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EPAS1 |
endothelial PAS domain protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of EPAS1 mRNA |
CTD |
PMID:32035215 |
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NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697
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G |
EPB41L1 |
erythrocyte membrane protein band 4.1 like 1 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of EPB41L1 promoter |
CTD |
PMID:26307267 |
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NCBI chr20:36,091,414...36,232,799
Ensembl chr20:36,091,504...36,232,799
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EPCAM |
epithelial cell adhesion molecule |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of EPCAM mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of EPCAM mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:47,369,311...47,387,020
Ensembl chr 2:47,345,158...47,387,601
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G |
EPHX1 |
epoxide hydrolase 1 |
increases expression multiple interactions increases methylation |
ISO |
Methamphetamine results in increased expression of EPHX1 mRNA; Methamphetamine results in increased expression of EPHX1 protein EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; EPHX1 protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; Methamphetamine promotes the reaction [PRKCD protein modified form binds to EPHX1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of EPHX1 protein] Methamphetamine results in increased methylation of EPHX1 promoter |
CTD |
PMID:26307267 PMID:31422080 |
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NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563
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EPOR |
erythropoietin receptor |
decreases expression |
ISO |
Methamphetamine results in decreased expression of EPOR mRNA |
CTD |
PMID:15644446 |
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NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342
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G |
ERN1 |
endoplasmic reticulum to nucleus signaling 1 |
increases expression multiple interactions increases phosphorylation |
ISO EXP |
Methamphetamine results in increased expression of ERN1 protein modified form ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; ERN1 protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein]; ERN1 protein affects the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of ERN1 protein] Melatonin inhibits the reaction [Methamphetamine results in increased expression of ERN1 protein modified form] |
CTD |
PMID:27323860 PMID:28070110 |
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NCBI chr17:64,039,142...64,130,144
Ensembl chr17:64,039,080...64,130,819
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G |
ERRFI1 |
ERBB receptor feedback inhibitor 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of ERRFI1 mRNA Methamphetamine results in increased expression of ERRFI1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:8,011,727...8,026,309
Ensembl chr 1:8,004,404...8,026,309
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G |
ESR1 |
estrogen receptor 1 |
increases response to substance |
EXP |
ESR1 gene polymorphism results in increased susceptibility to Methamphetamine |
CTD |
PMID:19386276 |
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NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619
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G |
EVC2 |
EvC ciliary complex subunit 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of EVC2 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 4:5,529,011...5,709,548
Ensembl chr 4:5,542,772...5,709,548
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G |
EXOC7 |
exocyst complex component 7 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of EXOC7 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:76,081,016...76,103,787
Ensembl chr17:76,081,016...76,121,576
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G |
F11R |
F11 receptor |
multiple interactions increases expression |
ISO |
Luteolin inhibits the reaction [Methamphetamine results in increased expression of F11R mRNA] |
CTD |
PMID:32035215 |
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NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,175
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G |
F3 |
coagulation factor III, tissue factor |
increases methylation |
ISO |
Methamphetamine results in increased methylation of F3 promoter |
CTD |
PMID:26307267 |
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NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759
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G |
FAAH |
fatty acid amide hydrolase |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of FAAH mRNA Methamphetamine results in decreased expression of FAAH mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848
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G |
FABP3 |
fatty acid binding protein 3 |
affects response to substance increases expression |
ISO EXP |
FABP3 affects the susceptibility to Methamphetamine Methamphetamine results in increased expression of FABP3 mRNA |
CTD |
PMID:20181611 PMID:25290377 |
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NCBI chr 1:31,359,588...31,373,076
Ensembl chr 1:31,365,253...31,376,850
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FABP7 |
fatty acid binding protein 7 |
affects expression |
ISO |
Methamphetamine affects the expression of FABP7 protein |
CTD |
PMID:17904249 |
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NCBI chr 6:122,749,201...122,784,074
Ensembl chr 6:122,779,716...122,784,074
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FAH |
fumarylacetoacetate hydrolase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of FAH mRNA |
CTD |
PMID:19564919 |
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NCBI chr15:80,152,789...80,186,949
Ensembl chr15:80,152,490...80,186,946
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G |
FAM110A |
family with sequence similarity 110 member A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of FAM110A mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:833,715...846,277
Ensembl chr20:833,715...857,463
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G |
FAM193A |
family with sequence similarity 193 member A |
increases expression |
ISO |
Methamphetamine results in increased expression of FAM193A mRNA |
CTD |
PMID:26307267 |
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NCBI chr 4:2,535,375...2,732,573
Ensembl chr 4:2,536,647...2,732,573
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G |
FAM193B |
family with sequence similarity 193 member B |
increases expression |
ISO |
Methamphetamine results in increased expression of FAM193B mRNA |
CTD |
PMID:26307267 |
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NCBI chr 5:177,519,788...177,554,563
Ensembl chr 5:177,519,789...177,554,586
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G |
FANK1 |
fibronectin type III and ankyrin repeat domains 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of FANK1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:125,896,564...126,009,592
Ensembl chr10:125,896,564...126,009,592
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G |
FAS |
Fas cell surface death receptor |
decreases expression increases expression |
ISO |
Methamphetamine results in decreased expression of FAS mRNA Methamphetamine results in increased expression of FAS mRNA |
CTD |
PMID:15644446 |
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NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605
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G |
FASLG |
Fas ligand |
increases expression |
ISO |
Methamphetamine results in increased expression of FASLG mRNA; Methamphetamine results in increased expression of FASLG protein |
CTD |
PMID:15644446 |
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NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876
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G |
FASTKD3 |
FAST kinase domains 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of FASTKD3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 5:7,859,159...7,869,031
Ensembl chr 5:7,859,159...7,869,037
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G |
FBLIM1 |
filamin binding LIM protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of FBLIM1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:15,756,638...15,786,589
Ensembl chr 1:15,756,607...15,786,594
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G |
FBXL4 |
F-box and leucine rich repeat protein 4 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of FBXL4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:98,868,535...98,947,946
Ensembl chr 6:98,868,535...98,948,006
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G |
FBXO28 |
F-box protein 28 |
increases expression |
ISO |
Methamphetamine results in increased expression of FBXO28 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:224,114,111...224,162,047
Ensembl chr 1:224,114,111...224,162,047
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G |
FBXO32 |
F-box protein 32 |
increases expression |
ISO |
Methamphetamine results in increased expression of FBXO32 mRNA |
CTD |
PMID:23933405 |
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NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206
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G |
FBXO33 |
F-box protein 33 |
increases expression |
ISO |
Methamphetamine results in increased expression of FBXO33 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:39,397,684...39,432,433
Ensembl chr14:39,397,684...39,432,466
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G |
FCGBP |
Fc gamma binding protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of FCGBP mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:39,863,323...39,934,634
Ensembl chr19:39,863,323...39,934,626
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G |
FGF2 |
fibroblast growth factor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of FGF2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236
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G |
FGF4 |
fibroblast growth factor 4 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of FGF4 mRNA Methamphetamine results in increased expression of FGF4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:69,771,022...69,775,341
Ensembl chr11:69,771,022...69,775,341
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G |
FGFR3 |
fibroblast growth factor receptor 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of FGFR3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 4:1,793,293...1,808,867
Ensembl chr 4:1,793,293...1,808,872
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G |
FHIT |
fragile histidine triad diadenosine triphosphatase |
affects response to substance |
EXP |
FHIT gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459
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G |
FJX1 |
four-jointed box kinase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of FJX1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:35,618,460...35,620,865
Ensembl chr11:35,618,460...35,620,865
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G |
FKBP15 |
FKBP prolyl isomerase family member 15 |
affects response to substance |
EXP |
FKBP15 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 9:113,161,006...113,221,277
Ensembl chr 9:113,161,006...113,221,458
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G |
FKBP4 |
FKBP prolyl isomerase 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of FKBP4 mRNA |
CTD |
PMID:19149911 |
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NCBI chr12:2,794,970...2,805,423
Ensembl chr12:2,794,970...2,805,423
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FLNA |
filamin A |
increases expression |
ISO |
Methamphetamine results in increased expression of FLNA mRNA |
CTD |
PMID:26307267 |
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NCBI chr X:154,348,531...154,374,634
Ensembl chr X:154,348,524...154,374,634
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FLNB |
filamin B |
increases expression |
ISO |
Methamphetamine results in increased expression of FLNB mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:58,008,422...58,172,251
Ensembl chr 3:58,008,398...58,172,251
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FLNC |
filamin C |
increases expression |
ISO |
Methamphetamine results in increased expression of FLNC mRNA |
CTD |
PMID:26307267 PMID:36914120 |
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NCBI chr 7:128,830,406...128,859,272
Ensembl chr 7:128,830,406...128,859,274
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G |
FLT1 |
fms related receptor tyrosine kinase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of FLT1 mRNA |
CTD |
PMID:26307267 PMID:32035215 |
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NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145
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G |
FMO2 |
flavin containing dimethylaniline monoxygenase 2 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of FMO2 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of FMO2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:171,185,208...171,212,686
Ensembl chr 1:171,185,249...171,212,686
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G |
FMO3 |
flavin containing dimethylaniline monoxygenase 3 |
increases metabolic processing |
EXP |
FMO3 protein results in increased metabolism of Methamphetamine |
CTD |
PMID:27320963 |
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NCBI chr 1:171,090,905...171,117,819
Ensembl chr 1:171,090,901...171,117,819
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G |
FN1 |
fibronectin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of FN1 mRNA |
CTD |
PMID:12766323 |
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NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073
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G |
FOS |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions increases expression affects response to substance |
ISO |
Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]; FOS protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Idazoxan inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]]; Lidocaine inhibits the reaction [Bee Venoms promotes the reaction [Methamphetamine results in increased expression of FOS protein]] Methamphetamine results in increased expression of FOS mRNA; Methamphetamine results in increased expression of FOS protein [Methamphetamine co-treated with SCH 23390] results in increased expression of FOS mRNA; Carbamazepine inhibits the reaction [Methamphetamine results in increased expression of FOS protein]; Oxytocin inhibits the reaction [Methamphetamine results in increased expression of FOS protein] Methamphetamine results in increased expression of FOS; Methamphetamine results in increased expression of FOS protein FOS mRNA affects the susceptibility to Methamphetamine; FOS protein affects the susceptibility to Methamphetamine |
CTD |
PMID:10559418 PMID:10731628 PMID:11754491 PMID:12050851 PMID:19564919 PMID:19689456 PMID:20731630 PMID:20950675 More...
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NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230
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G |
FOSB |
FosB proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
methamphetamine increases expression of Fosb protein in the ventral tegmental area and nucleus accumbens |
RGD |
PMID:28782589 |
RGD:401900303 |
NCBI chr19:45,467,996...45,475,179
Ensembl chr19:45,467,995...45,475,179
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G |
FOSL1 |
FOS like 1, AP-1 transcription factor subunit |
increases expression |
ISO |
Methamphetamine results in increased expression of FOSL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:65,892,049...65,900,545
Ensembl chr11:65,892,049...65,900,573
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G |
FOXE1 |
forkhead box E1 |
increases expression |
ISO |
Methamphetamine results in increased expression of FOXE1 mRNA; Methamphetamine results in increased expression of FOXE1 protein |
CTD |
PMID:28341135 |
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NCBI chr 9:97,853,226...97,856,717
Ensembl chr 9:97,853,226...97,856,717
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G |
FOXO3 |
forkhead box O3 |
affects localization increases phosphorylation decreases phosphorylation multiple interactions |
ISO |
Methamphetamine affects the localization of FOXO3 protein Methamphetamine results in increased phosphorylation of FOXO3 protein Methamphetamine results in decreased phosphorylation of FOXO3 protein 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in decreased phosphorylation of FOXO3 protein]; DDIT3 protein affects the reaction [Methamphetamine results in decreased phosphorylation of FOXO3 protein]; Methamphetamine promotes the reaction [FOXO3 protein binds to DDIT3 protein] |
CTD |
PMID:34214594 PMID:35863504 |
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NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
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G |
FST |
follistatin |
decreases expression |
ISO |
Methamphetamine results in decreased expression of FST mRNA |
CTD |
PMID:28619521 |
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NCBI chr 5:53,480,629...53,487,134
Ensembl chr 5:53,480,626...53,487,134
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G |
FTCD |
formimidoyltransferase cyclodeaminase |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of FTCD mRNA Methamphetamine results in increased expression of FTCD mRNA |
CTD |
PMID:19564919 |
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NCBI chr21:46,136,262...46,155,579
Ensembl chr21:46,136,160...46,155,579
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G |
FUZ |
fuzzy planar cell polarity protein |
increases expression |
ISO |
Methamphetamine results in increased expression of FUZ mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:49,806,866...49,813,553
Ensembl chr19:49,806,866...49,817,376
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G |
FYN |
FYN proto-oncogene, Src family tyrosine kinase |
increases expression |
ISO |
Methamphetamine results in increased expression of FYN mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:111,660,332...111,873,452
Ensembl chr 6:111,660,332...111,873,452
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GABARAPL2 |
GABA type A receptor associated protein like 2 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of GABARAPL2 promoter |
CTD |
PMID:26307267 |
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NCBI chr16:75,566,379...75,577,881
Ensembl chr16:75,566,375...75,577,881
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G |
GABBR2 |
gamma-aminobutyric acid type B receptor subunit 2 |
multiple interactions |
EXP |
Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
CTD |
PMID:21729720 |
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NCBI chr 9:98,288,109...98,708,935
Ensembl chr 9:98,288,109...98,708,935
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G |
GABPA |
GA binding protein transcription factor subunit alpha |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of GABPA mRNA Lithium inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of GABPA mRNA] |
CTD |
PMID:19149911 |
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NCBI chr21:25,734,972...25,772,460
Ensembl chr21:25,734,570...25,772,460
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G |
GABRA1 |
gamma-aminobutyric acid type A receptor subunit alpha1 |
multiple interactions |
EXP |
Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
CTD |
PMID:21729720 |
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NCBI chr 5:161,847,191...161,899,971
Ensembl chr 5:161,847,063...161,899,981
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G |
GABRG2 |
gamma-aminobutyric acid type A receptor subunit gamma2 |
increases response to substance multiple interactions |
EXP |
GABRG2 gene results in increased susceptibility to Methamphetamine Methamphetamine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABBR2 protein co-treated with GABRG2 protein]] |
CTD |
PMID:15772696 PMID:21729720 |
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NCBI chr 5:162,067,465...162,155,539
Ensembl chr 5:162,000,057...162,162,977
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G |
GABRG3 |
gamma-aminobutyric acid type A receptor subunit gamma3 |
increases expression |
ISO |
Methamphetamine results in increased expression of GABRG3 mRNA |
CTD |
PMID:15644446 |
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NCBI chr15:26,971,181...27,541,984
Ensembl chr15:26,971,181...27,541,984
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G |
GABRR3 |
gamma-aminobutyric acid type A receptor subunit rho3 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of GABRR3 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of GABRR3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:97,985,102...98,035,315
Ensembl chr 3:97,985,102...98,035,315
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G |
GAD2 |
glutamate decarboxylase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of GAD2 mRNA |
CTD |
PMID:15601951 |
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NCBI chr10:26,216,372...26,304,558
Ensembl chr10:26,216,665...26,304,558
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G |
GADD45B |
growth arrest and DNA damage inducible beta |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45B mRNA Methamphetamine results in increased expression of GADD45B mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:2,476,127...2,478,257
Ensembl chr19:2,476,122...2,478,259
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G |
GADD45G |
growth arrest and DNA damage inducible gamma |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of GADD45G mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of GADD45G mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:89,605,012...89,606,555
Ensembl chr 9:89,605,012...89,606,555
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GAL |
galanin and GMAP prepropeptide |
increases expression decreases expression |
EXP ISO |
Methamphetamine results in increased expression of GAL mRNA Methamphetamine results in decreased expression of GAL mRNA |
CTD |
PMID:19564919 PMID:25290377 |
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NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175
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G |
GALK1 |
galactokinase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GALK1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:75,751,469...75,765,192
Ensembl chr17:75,751,594...75,765,236
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G |
GALNTL6 |
polypeptide N-acetylgalactosaminyltransferase like 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GALNTL6 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 4:171,813,404...173,041,559
Ensembl chr 4:171,812,254...173,041,559
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G |
GALT |
galactose-1-phosphate uridylyltransferase |
increases expression |
ISO |
Methamphetamine results in increased expression of GALT mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:34,646,675...34,651,035
Ensembl chr 9:34,638,133...34,651,035
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G |
GAP43 |
growth associated protein 43 |
multiple interactions decreases expression |
ISO |
Melatonin inhibits the reaction [Methamphetamine results in decreased expression of GAP43 protein] |
CTD |
PMID:19409439 |
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NCBI chr 3:115,623,510...115,721,483
Ensembl chr 3:115,623,510...115,721,490
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G |
GARIN5A |
golgi associated RAB2 interactor 5A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GARIN5A mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:50,466,788...50,476,848
Ensembl chr19:50,466,785...50,476,848
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G |
GAS5 |
growth arrest specific 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of GAS5 mRNA |
CTD |
PMID:28619521 |
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NCBI chr 1:173,863,901...173,869,045
Ensembl chr 1:173,858,559...173,868,882
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G |
GAS8 |
growth arrest specific 8 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GAS8 mRNA Methamphetamine results in decreased expression of GAS8 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:90,019,633...90,044,960
Ensembl chr16:90,019,629...90,044,975
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G |
GATA4 |
GATA binding protein 4 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of GATA4 mRNA; Methamphetamine results in increased expression of GATA4 protein GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN1A protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of CDKN2A protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of EDN3 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of GDF15 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of GLB1 protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1A mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1B mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1B protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL6 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL6 protein]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of TGFB2 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased phosphorylation of RELA protein] |
CTD |
PMID:36914120 |
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NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002
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G |
GATAD2B |
GATA zinc finger domain containing 2B |
increases expression |
ISO |
Methamphetamine results in increased expression of GATAD2B mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:153,804,725...153,922,972
Ensembl chr 1:153,789,030...153,923,360
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G |
GBF1 |
golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GBF1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:102,230,643...102,382,896
Ensembl chr10:102,245,371...102,382,899
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G |
GBGT1 |
globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group) |
increases expression |
ISO |
Methamphetamine results in increased expression of GBGT1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 9:133,152,948...133,163,914
Ensembl chr 9:133,152,948...133,163,933
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G |
GCH1 |
GTP cyclohydrolase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GCH1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826
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G |
GCSH |
glycine cleavage system protein H |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GCSH mRNA |
CTD |
PMID:19149911 |
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NCBI chr16:81,081,945...81,096,395
Ensembl chr16:81,081,945...81,096,395
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G |
GDA |
guanine deaminase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GDA protein |
CTD |
PMID:19826936 |
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NCBI chr 9:72,114,608...72,259,869
Ensembl chr 9:72,114,595...72,257,193
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G |
GDF15 |
growth differentiation factor 15 |
increases expression multiple interactions |
EXP ISO |
Methamphetamine results in increased expression of GDF15 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of GDF15 mRNA; GATA4 protein affects the reaction [Methamphetamine results in increased expression of GDF15 mRNA] |
CTD |
PMID:19564919 PMID:25290377 PMID:36914120 |
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NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176
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G |
GDI1 |
GDP dissociation inhibitor 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GDI1 protein |
CTD |
PMID:19826936 |
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NCBI chr X:154,437,154...154,443,467
Ensembl chr X:154,436,913...154,443,467
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G |
GDNF |
glial cell derived neurotrophic factor |
decreases response to substance |
ISO |
GDNF protein results in decreased susceptibility to Methamphetamine |
CTD |
PMID:17356005 |
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NCBI chr 5:37,812,677...37,840,041
Ensembl chr 5:37,812,677...37,840,041
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G |
GEM |
GTP binding protein overexpressed in skeletal muscle |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] affects the expression of GEM mRNA Methamphetamine results in increased expression of GEM mRNA |
CTD |
PMID:19564919 |
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NCBI chr 8:94,249,253...94,262,319
Ensembl chr 8:94,249,253...94,262,350
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G |
GFAP |
glial fibrillary acidic protein |
multiple interactions increases expression affects expression |
ISO |
3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [[PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein]; [PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein; isoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; Raclopride inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP mRNA]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; TAAR1 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein] Methamphetamine results in increased expression of GFAP mRNA; Methamphetamine results in increased expression of GFAP protein Methamphetamine affects the expression of GFAP protein |
CTD |
PMID:9427479 PMID:9634552 PMID:9739098 PMID:10773198 PMID:12766323 PMID:15337264 PMID:15644446 PMID:16088948 PMID:17262233 PMID:19834288 PMID:21867746 PMID:24072398 PMID:26283213 PMID:28919515 PMID:29467000 PMID:32278788 More...
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NCBI chr17:44,903,159...44,915,500
Ensembl chr17:44,903,159...44,916,937
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G |
GFRA2 |
GDNF family receptor alpha 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of GFRA2 mRNA |
CTD |
PMID:15644446 |
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NCBI chr 8:21,690,398...21,812,345
Ensembl chr 8:21,690,398...21,812,357
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G |
GFRA4 |
GDNF family receptor alpha 4 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of GFRA4 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of GFRA4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:3,659,248...3,663,399
Ensembl chr20:3,659,248...3,663,399
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G |
GIGYF1 |
GRB10 interacting GYF protein 1 |
increases methylation increases expression |
ISO |
Methamphetamine results in increased methylation of GIGYF1 promoter Methamphetamine results in increased expression of GIGYF1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:100,679,507...100,694,250
Ensembl chr 7:100,679,507...100,694,250
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G |
GIGYF2 |
GRB10 interacting GYF protein 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of GIGYF2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:232,697,331...232,860,605
Ensembl chr 2:232,697,299...232,860,605
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G |
GIPC3 |
GIPC PDZ domain containing family member 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GIPC3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:3,585,478...3,593,541
Ensembl chr19:3,585,478...3,593,541
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G |
GJA4 |
gap junction protein alpha 4 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GJA4 mRNA Methamphetamine results in decreased expression of GJA4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:34,792,999...34,795,747
Ensembl chr 1:34,792,999...34,795,747
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G |
GJA5 |
gap junction protein alpha 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of GJA5 mRNA |
CTD |
PMID:15644446 |
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NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362
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G |
GLB1 |
galactosidase beta 1 |
multiple interactions increases expression |
ISO |
GATA4 protein affects the reaction [Methamphetamine results in increased expression of GLB1 protein] |
CTD |
PMID:36914120 |
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NCBI chr 3:32,961,108...33,097,146
Ensembl chr 3:32,996,609...33,097,202
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G |
GLI1 |
GLI family zinc finger 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GLI1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:57,459,785...57,472,268
Ensembl chr12:57,459,785...57,472,268
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G |
GLO1 |
glyoxalase I |
increases expression |
ISO |
Methamphetamine results in increased expression of GLO1 protein |
CTD |
PMID:19826936 |
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NCBI chr 6:38,675,925...38,703,145
Ensembl chr 6:38,675,925...38,703,145
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G |
GLS |
glutaminase |
multiple interactions decreases expression |
ISO |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GLS mRNA] |
CTD |
PMID:19149911 |
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NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
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G |
GLYCTK |
glycerate kinase |
increases methylation |
ISO |
Methamphetamine results in increased methylation of GLYCTK promoter |
CTD |
PMID:26307267 |
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NCBI chr 3:52,287,828...52,295,257
Ensembl chr 3:52,287,089...52,295,257
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G |
GM2A |
ganglioside GM2 activator |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GM2A mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:151,253,185...151,270,440
Ensembl chr 5:151,212,150...151,270,440
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G |
GMFB |
glia maturation factor beta |
affects expression |
ISO |
Methamphetamine affects the expression of GMFB protein |
CTD |
PMID:17904249 |
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NCBI chr14:54,474,485...54,488,980
Ensembl chr14:54,474,484...54,489,025
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G |
GNB1 |
G protein subunit beta 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GNB1 protein |
CTD |
PMID:19826936 |
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NCBI chr 1:1,785,286...1,891,087
Ensembl chr 1:1,785,285...1,892,292
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G |
GNB2 |
G protein subunit beta 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GNB2 protein |
CTD |
PMID:19826936 |
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NCBI chr 7:100,673,740...100,679,169
Ensembl chr 7:100,673,567...100,679,174
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G |
GNB3 |
G protein subunit beta 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GNB3 protein |
CTD |
PMID:19826936 |
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NCBI chr12:6,840,925...6,847,393
Ensembl chr12:6,839,954...6,847,393
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G |
GOLGB1 |
golgin B1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GOLGB1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:121,663,201...121,749,966
Ensembl chr 3:121,663,199...121,749,966
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G |
GOLPH3 |
golgi phosphoprotein 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of GOLPH3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:32,124,716...32,174,319
Ensembl chr 5:32,124,716...32,174,319
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G |
GON4L |
gon-4 like |
increases expression |
ISO |
Methamphetamine results in increased expression of GON4L mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:155,745,112...155,859,431
Ensembl chr 1:155,749,659...155,859,400
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G |
GOT2 |
glutamic-oxaloacetic transaminase 2 |
multiple interactions decreases expression |
ISO |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of GOT2 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GOT2 mRNA] |
CTD |
PMID:19149911 |
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NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
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G |
GPNMB |
glycoprotein nmb |
increases expression |
EXP |
Methamphetamine results in increased expression of GPNMB mRNA |
CTD |
PMID:25290377 |
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NCBI chr 7:23,246,775...23,275,108
Ensembl chr 7:23,235,967...23,275,108
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G |
GPR150 |
G protein-coupled receptor 150 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of GPR150 mRNA Methamphetamine results in decreased expression of GPR150 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:95,620,087...95,622,142
Ensembl chr 5:95,620,087...95,622,142
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G |
GPR17 |
G protein-coupled receptor 17 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GPR17 mRNA |
CTD |
PMID:28619521 |
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NCBI chr 2:127,646,153...127,652,639
Ensembl chr 2:127,645,864...127,652,639
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G |
GPR19 |
G protein-coupled receptor 19 |
increases expression |
ISO |
Methamphetamine results in increased expression of GPR19 mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:12,660,890...12,717,246
Ensembl chr12:12,660,890...12,696,207
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G |
GPR4 |
G protein-coupled receptor 4 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of GPR4 mRNA Methamphetamine results in increased expression of GPR4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:45,589,764...45,602,212
Ensembl chr19:45,589,764...45,602,212
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G |
GPR65 |
G protein-coupled receptor 65 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of GPR65 mRNA Methamphetamine results in increased expression of GPR65 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:88,005,135...88,014,811
Ensembl chr14:88,005,135...88,014,811
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G |
GPSM1 |
G protein signaling modulator 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GPSM1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:136,327,539...136,359,601
Ensembl chr 9:136,327,476...136,359,605
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G |
GPT |
glutamic--pyruvic transaminase |
multiple interactions decreases expression |
ISO |
Lithium inhibits the reaction [Methamphetamine results in decreased expression of GPT mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of GPT mRNA] |
CTD |
PMID:19149911 |
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NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174
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G |
GPX1 |
glutathione peroxidase 1 |
multiple interactions affects response to substance |
ISO |
GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; GPX1 protein affects the reaction [Methamphetamine results in increased activity of RELA protein]; Methamphetamine affects the expression of and affects the activity of GPX1 protein; pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]] GPX1 protein affects the susceptibility to Methamphetamine |
CTD |
PMID:34082047 |
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NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605
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G |
GRB2 |
growth factor receptor bound protein 2 |
affects expression |
ISO |
Methamphetamine affects the expression of GRB2 protein |
CTD |
PMID:17904249 |
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NCBI chr17:75,318,076...75,405,678
Ensembl chr17:75,318,076...75,405,709
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G |
GRIA1 |
glutamate ionotropic receptor AMPA type subunit 1 |
affects expression increases expression |
ISO |
Methamphetamine affects the expression of GRIA1 mRNA Methamphetamine increases expression of Gria1 protein in hippocampus, striatum, prefrontal cortex |
CTD RGD |
PMID:18419818 PMID:37778205 |
RGD:405100237 |
NCBI chr 5:153,489,615...153,813,869
Ensembl chr 5:153,489,615...153,813,869
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G |
GRIA2 |
glutamate ionotropic receptor AMPA type subunit 2 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of GRIA2 mRNA; Methamphetamine results in increased expression of GRIA2 protein 3-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine inhibits the reaction [Methamphetamine results in increased expression of GRIA2 protein] |
CTD |
PMID:18419818 PMID:23711322 |
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NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146
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G |
GRIA3 |
glutamate ionotropic receptor AMPA type subunit 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of GRIA3 mRNA |
CTD |
PMID:18419818 |
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NCBI chr X:123,184,278...123,490,915
Ensembl chr X:123,184,153...123,490,915
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G |
GRIN1 |
glutamate ionotropic receptor NMDA type subunit 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GRIN1 mRNA |
CTD |
PMID:18419818 |
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NCBI chr 9:137,139,154...137,168,756
Ensembl chr 9:137,138,346...137,168,756
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G |
GRIN2A |
glutamate ionotropic receptor NMDA type subunit 2A |
increases expression |
ISO |
Methamphetamine results in increased expression of GRIN2A mRNA |
CTD |
PMID:18419818 |
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NCBI chr16:9,753,404...10,182,908
Ensembl chr16:9,753,404...10,182,928
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G |
GRIN2B |
glutamate ionotropic receptor NMDA type subunit 2B |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of GRIN2B protein Methamphetamine results in decreased expression of GRIN2B mRNA Methamphetamine results in increased expression of GRIN2B mRNA |
CTD |
PMID:17105907 PMID:18419818 PMID:32035215 PMID:32203791 |
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NCBI chr12:13,537,337...13,982,134
Ensembl chr12:13,437,942...13,982,002
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G |
GRIN2D |
glutamate ionotropic receptor NMDA type subunit 2D |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GRIN2D mRNA |
CTD |
PMID:21886566 |
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NCBI chr19:48,393,668...48,444,931
Ensembl chr19:48,393,668...48,444,931
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G |
GRINA |
glutamate ionotropic receptor NMDA type subunit associated protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GRINA mRNA |
CTD |
PMID:26307267 |
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NCBI chr 8:143,990,056...143,993,415
Ensembl chr 8:143,990,056...143,993,415
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G |
GRIP2 |
glutamate receptor interacting protein 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of GRIP2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:14,489,107...14,603,017
Ensembl chr 3:14,489,107...14,556,075
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G |
GRIPAP1 |
GRIP1 associated protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GRIPAP1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr X:48,973,723...49,002,264
Ensembl chr X:48,973,720...49,002,265
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G |
GRM1 |
glutamate metabotropic receptor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of GRM1 mRNA |
CTD |
PMID:18419818 |
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NCBI chr 6:146,027,707...146,437,601
Ensembl chr 6:146,027,646...146,437,601
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G |
GRM2 |
glutamate metabotropic receptor 2 |
increases response to substance multiple interactions |
EXP ISO |
GRM2 gene SNP results in increased susceptibility to Methamphetamine [Piperidines results in increased activity of GRM2 protein] which results in decreased susceptibility to Methamphetamine |
CTD |
PMID:20211215 PMID:21366332 |
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NCBI chr 3:51,707,068...51,718,613
Ensembl chr 3:51,707,068...51,718,613
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G |
GRM3 |
glutamate metabotropic receptor 3 |
decreases expression increases expression |
ISO |
Methamphetamine results in decreased expression of GRM3 mRNA Methamphetamine results in increased expression of GRM3 mRNA |
CTD |
PMID:15644446 PMID:18419818 |
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NCBI chr 7:86,643,909...86,864,879
Ensembl chr 7:86,643,909...86,864,879
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G |
GRM5 |
glutamate metabotropic receptor 5 |
multiple interactions increases expression |
ISO |
[6-methyl-2-(phenylethynyl)pyridine binds to and results in decreased activity of GRM5 protein] inhibits the reaction [Methamphetamine results in decreased abundance of Dopamine]; [6-methyl-2-(phenylethynyl)pyridine binds to and results in decreased activity of GRM5 protein] inhibits the reaction [Methamphetamine results in increased secretion of Dopamine] Methamphetamine results in increased expression of GRM5 mRNA; Methamphetamine results in increased expression of GRM5 protein |
CTD |
PMID:12907309 PMID:18419818 PMID:23711322 |
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NCBI chr11:88,504,642...89,065,982
Ensembl chr11:88,504,576...89,065,982
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G |
GSK3A |
glycogen synthase kinase 3 alpha |
decreases expression multiple interactions affects phosphorylation |
ISO EXP |
Methamphetamine results in decreased expression of GSK3A protein Rosiglitazone affects the reaction [Methamphetamine affects the phosphorylation of GSK3A protein] |
CTD |
PMID:16192988 PMID:31270305 |
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NCBI chr19:42,230,190...42,242,602
Ensembl chr19:42,226,225...42,242,625
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G |
GSK3B |
glycogen synthase kinase 3 beta |
multiple interactions affects phosphorylation increases expression decreases phosphorylation increases phosphorylation |
ISO EXP |
Rosiglitazone inhibits the reaction [Methamphetamine results in increased phosphorylation of GSK3B protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GSK3B protein modified form]; TWS 119 inhibits the reaction [Methamphetamine results in increased phosphorylation of GSK3B protein] Methamphetamine affects the phosphorylation of GSK3B protein Metformin inhibits the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of GSK3B protein]; Methamphetamine results in increased expression of and results in increased phosphorylation of GSK3B protein Rosiglitazone affects the reaction [Methamphetamine affects the phosphorylation of GSK3B protein] Methamphetamine results in decreased phosphorylation of GSK3B protein |
CTD |
PMID:29981415 PMID:30367931 PMID:30742852 PMID:31270305 PMID:32278788 PMID:35863504 More...
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NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994
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G |
GSR |
glutathione-disulfide reductase |
multiple interactions decreases activity |
ISO |
Metformin inhibits the reaction [Methamphetamine results in decreased activity of GSR protein] |
CTD |
PMID:30742852 |
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NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846
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G |
GSTM1 |
glutathione S-transferase mu 1 |
affects response to substance decreases response to substance |
EXP |
GSTM1 gene polymorphism affects the susceptibility to Methamphetamine GSTM1 protein results in decreased susceptibility to Methamphetamine |
CTD |
PMID:15048646 PMID:19254865 |
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NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039
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G |
GSTP1 |
glutathione S-transferase pi 1 |
increases response to substance |
EXP |
GSTP1 exon polymorphism results in increased susceptibility to Methamphetamine |
CTD |
PMID:15729709 |
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NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656
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G |
GSTT1 |
glutathione S-transferase theta 1 |
affects response to substance |
EXP |
GSTT1 gene polymorphism affects the susceptibility to Methamphetamine; GSTT1 protein affects the susceptibility to Methamphetamine |
CTD |
PMID:18186040 PMID:19254865 |
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G |
GTPBP10 |
GTP binding protein 10 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of GTPBP10 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 7:90,346,716...90,391,453
Ensembl chr 7:90,335,223...90,391,453
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G |
H3-3A |
H3.3 histone A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of H3F3A mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:226,061,831...226,072,019
Ensembl chr 1:226,061,851...226,072,019
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G |
H4C9 |
H4 clustered histone 9 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of HIST1H4B mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of HIST1H4B mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:27,139,282...27,139,678
Ensembl chr 6:27,139,282...27,139,678
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G |
HAVCR1 |
hepatitis A virus cellular receptor 1 |
multiple interactions increases expression |
ISO |
NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of HAVCR1 protein]; sulforaphane inhibits the reaction [Methamphetamine results in increased expression of HAVCR1 protein] |
CTD |
PMID:37567421 |
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NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396
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G |
HBA2 |
hemoglobin subunit alpha 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HBA-A3 mRNA |
CTD |
PMID:32035215 |
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NCBI chr16:172,876...173,710
Ensembl chr16:172,876...173,710
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G |
HCN4 |
hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of HCN4 mRNA |
CTD |
PMID:15644446 |
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NCBI chr15:73,319,859...73,368,958
Ensembl chr15:73,319,859...73,368,958
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G |
HCRT |
hypocretin neuropeptide precursor |
increases methylation multiple interactions affects expression |
ISO |
Methamphetamine results in increased methylation of HCRT promoter [Methamphetamine co-treated with SCH 23390] results in decreased expression of HCRT mRNA Methamphetamine affects the expression of HCRT mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr17:42,184,060...42,185,452
Ensembl chr17:42,184,060...42,185,452
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G |
HDAC10 |
histone deacetylase 10 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HDAC10 mRNA |
CTD |
PMID:25452209 |
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NCBI chr22:50,245,183...50,251,265
Ensembl chr22:50,245,183...50,251,405
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G |
HDAC11 |
histone deacetylase 11 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HDAC11 mRNA |
CTD |
PMID:25452209 |
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NCBI chr 3:13,480,306...13,506,416
Ensembl chr 3:13,479,724...13,506,424
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G |
HDAC6 |
histone deacetylase 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HDAC6 mRNA |
CTD |
PMID:25452209 |
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NCBI chr X:48,801,398...48,824,982
Ensembl chr X:48,801,377...48,824,982
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G |
HDAC7 |
histone deacetylase 7 |
increases expression |
ISO |
Methamphetamine results in increased expression of HDAC7 mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:47,782,722...47,821,344
Ensembl chr12:47,782,722...47,833,132
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G |
HDAC8 |
histone deacetylase 8 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HDAC8 mRNA |
CTD |
PMID:25452209 |
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NCBI chr X:72,329,516...72,572,843
Ensembl chr X:72,329,516...72,573,101
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G |
HDAC9 |
histone deacetylase 9 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HDAC9 mRNA |
CTD |
PMID:25452209 |
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NCBI chr 7:18,086,825...19,002,416
Ensembl chr 7:18,086,949...19,002,416
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G |
HDC |
histidine decarboxylase |
multiple interactions affects response to substance |
ISO |
HDC protein affects the reaction [Methamphetamine results in decreased abundance of gamma-Aminobutyric Acid] HDC protein affects the susceptibility to Methamphetamine |
CTD |
PMID:12421355 |
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NCBI chr15:50,241,947...50,265,726
Ensembl chr15:50,241,947...50,265,965
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G |
HERC2 |
HECT and RLD domain containing E3 ubiquitin protein ligase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of HERC2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr15:28,111,040...28,322,179
Ensembl chr15:28,111,040...28,322,179
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G |
HERPUD1 |
homocysteine inducible ER protein with ubiquitin like domain 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of HERPUD1 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of HERPUD1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HERPUD1 mRNA] |
CTD |
PMID:19564919 |
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NCBI chr16:56,932,142...56,944,864
Ensembl chr16:56,932,142...56,944,864
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G |
HES1 |
hes family bHLH transcription factor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of HES1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
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G |
HES5 |
hes family bHLH transcription factor 5 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of HES5 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of HES5 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:2,528,745...2,530,263
Ensembl chr 1:2,528,745...2,530,263
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G |
HJURP |
Holliday junction recognition protein |
decreases expression |
EXP |
Methamphetamine results in decreased expression of HJURP mRNA |
CTD |
PMID:25290377 |
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NCBI chr 2:233,836,702...233,854,535
Ensembl chr 2:233,833,416...233,854,566
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G |
HK1 |
hexokinase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of HK1 mRNA |
CTD |
PMID:26307267 PMID:36914120 |
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NCBI chr10:69,270,000...69,401,882
Ensembl chr10:69,269,984...69,401,884
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G |
HLA-A |
major histocompatibility complex, class I, A |
increases expression |
ISO |
Methamphetamine results in increased expression of RT1-CE16 mRNA |
CTD |
PMID:32035215 |
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NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572
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G |
HMBS |
hydroxymethylbilane synthase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HMBS mRNA |
CTD |
PMID:24042092 |
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NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834
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G |
HMGA1 |
high mobility group AT-hook 1 |
increases expression multiple interactions |
EXP ISO |
Methamphetamine results in increased expression of HMGA1 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of HMGA1 mRNA |
CTD |
PMID:19564919 PMID:25290377 |
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NCBI chr 6:34,236,873...34,246,231
Ensembl chr 6:34,236,873...34,246,231
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G |
HMOX1 |
heme oxygenase 1 |
multiple interactions increases expression |
ISO |
[cobaltiprotoporphyrin results in increased expression of HMOX1 protein] which results in decreased susceptibility to Methamphetamine; [Methamphetamine co-treated with SCH 23390] results in increased expression of HMOX1 mRNA; [tin protoporphyrin IX results in decreased activity of HMOX1 protein] which results in decreased susceptibility to Methamphetamine; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 mRNA]; Methamphetamine promotes the reaction [Ascorbic Acid results in increased expression of HMOX1 protein]; Methamphetamine promotes the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 protein]; Methamphetamine results in increased expression of and results in increased activity of HMOX1 protein; SB 203580 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [Methamphetamine results in increased activity of HMOX1 protein] sulforaphane promotes the reaction [Methamphetamine results in increased expression of HMOX1 protein] Methamphetamine results in increased expression of HMOX1 mRNA; Methamphetamine results in increased expression of HMOX1 protein |
CTD |
PMID:19564919 PMID:19576919 PMID:23022510 PMID:23933405 PMID:28619521 PMID:37567421 More...
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NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214
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G |
HOMER1 |
homer scaffold protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of HOMER1 mRNA; Methamphetamine results in increased expression of HOMER1 mRNA alternative form; Methamphetamine results in increased expression of HOMER1 protein alternative form |
CTD |
PMID:15644446 PMID:17630046 |
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NCBI chr 5:79,372,636...79,514,134
Ensembl chr 5:79,372,636...79,514,134
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G |
HOXC10 |
homeobox C10 |
decreases methylation decreases expression |
ISO |
Methamphetamine results in decreased methylation of HOXC10 promoter Methamphetamine results in decreased expression of HOXC10 mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:53,985,146...53,990,279
Ensembl chr12:53,985,065...53,990,279
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G |
HPCA |
hippocalcin |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HPCA mRNA |
CTD |
PMID:15644446 |
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NCBI chr 1:32,885,996...32,894,646
Ensembl chr 1:32,885,994...32,898,441
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G |
HPSE |
heparanase |
increases methylation |
ISO |
Methamphetamine results in increased methylation of HPSE promoter |
CTD |
PMID:26307267 |
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NCBI chr 4:83,292,461...83,335,153
Ensembl chr 4:83,292,461...83,335,153
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G |
HR |
HR lysine demethylase and nuclear receptor corepressor |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HR mRNA |
CTD |
PMID:19564919 |
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NCBI chr 8:22,114,419...22,131,052
Ensembl chr 8:22,114,419...22,133,384
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G |
HRAS |
HRas proto-oncogene, GTPase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HRAS mRNA |
CTD |
PMID:15644446 |
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NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321
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G |
HRC |
histidine rich calcium binding protein |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of HRC mRNA Methamphetamine results in decreased expression of HRC mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:49,151,198...49,155,396
Ensembl chr19:49,151,198...49,155,396
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G |
HRK |
harakiri, BCL2 interacting protein |
increases expression |
EXP |
Methamphetamine results in increased expression of HRK mRNA |
CTD |
PMID:25290377 |
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NCBI chr12:116,856,144...116,881,441
Ensembl chr12:116,856,144...116,881,441
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G |
HS3ST4 |
heparan sulfate-glucosamine 3-sulfotransferase 4 |
affects response to substance |
EXP |
HS3ST4 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr16:25,691,959...26,137,685
Ensembl chr16:25,691,959...26,137,685
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G |
HSCB |
HscB mitochondrial iron-sulfur cluster cochaperone |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HSCB mRNA |
CTD |
PMID:19564919 |
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NCBI chr22:28,742,032...28,757,510
Ensembl chr22:28,742,039...28,757,515
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G |
HSD3B7 |
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HSD3B7 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:30,985,207...30,989,147
Ensembl chr16:30,985,207...30,989,147
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G |
HSF2BP |
heat shock transcription factor 2 binding protein |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of HSF2BP mRNA Methamphetamine results in increased expression of HSF2BP mRNA |
CTD |
PMID:19564919 |
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NCBI chr21:43,444,972...43,659,488
Ensembl chr21:43,529,186...43,659,488
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G |
HSP90AA1 |
heat shock protein 90 alpha family class A member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699
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G |
HSPA12B |
heat shock protein family A (Hsp70) member 12B |
increases expression decreases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of HSPA12B mRNA Methamphetamine results in decreased expression of HSPA12B mRNA SCH 23390 inhibits the reaction [Methamphetamine results in decreased expression of HSPA12B mRNA] |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr20:3,732,685...3,753,111
Ensembl chr20:3,732,685...3,753,111
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G |
HSPA1A |
heat shock protein family A (Hsp70) member 1A |
increases expression |
ISO |
Methamphetamine results in increased expression of HSPA1A protein |
CTD |
PMID:19826936 |
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NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946
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G |
HSPA5 |
heat shock protein family A (Hsp70) member 5 |
affects expression multiple interactions increases expression |
ISO EXP |
Methamphetamine affects the expression of HSPA5 protein 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of HSPA5 protein]; Naltrexone inhibits the reaction [Methamphetamine results in increased expression of HSPA5 mRNA]; norbinaltorphimine inhibits the reaction [Methamphetamine results in increased expression of HSPA5 mRNA]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of HSPA5 protein] Methamphetamine results in increased expression of HSPA5 mRNA; Methamphetamine results in increased expression of HSPA5 protein [Methamphetamine co-treated with SCH 23390] results in increased expression of HSPA5 mRNA; Melatonin promotes the reaction [Methamphetamine results in increased expression of HSPA5 mRNA]; Melatonin promotes the reaction [Methamphetamine results in increased expression of HSPA5 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPA5 mRNA] |
CTD |
PMID:19564919 PMID:19826936 PMID:27323860 PMID:28070110 PMID:32203791 PMID:33421459 PMID:36914120 More...
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NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,382
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G |
HSPA8 |
heat shock protein family A (Hsp70) member 8 |
increases expression |
ISO |
Methamphetamine results in increased expression of HSPA8 protein |
CTD |
PMID:19826936 |
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NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230
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G |
HSPA9 |
heat shock protein family A (Hsp70) member 9 |
multiple interactions increases expression |
ISO |
Lithium inhibits the reaction [Methamphetamine results in increased expression of HSPA9 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of HSPA9 mRNA] |
CTD |
PMID:19149911 |
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NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675
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G |
HSPB1 |
heat shock protein family B (small) member 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of HSPB1 mRNA; Methamphetamine results in increased expression of HSPB1 protein [Methamphetamine co-treated with SCH 23390] results in increased expression of HSPB1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPB1 mRNA] |
CTD |
PMID:12684743 PMID:19564919 PMID:26307267 PMID:36914120 |
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NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295
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G |
HSPB8 |
heat shock protein family B (small) member 8 |
multiple interactions increases expression |
ISO |
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of HSPB8 mRNA] |
CTD |
PMID:19564919 |
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NCBI chr12:119,178,931...119,194,746
Ensembl chr12:119,171,555...119,224,855
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G |
HSPD1 |
heat shock protein family D (Hsp60) member 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HSPD1 protein |
CTD |
PMID:19826936 |
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NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737
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G |
HSPG2 |
heparan sulfate proteoglycan 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of HSPG2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:21,822,244...21,937,310
Ensembl chr 1:21,822,244...21,937,310
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G |
HTR1A |
5-hydroxytryptamine receptor 1A |
increases response to substance multiple interactions |
EXP ISO |
HTR1A gene SNP results in increased susceptibility to Methamphetamine [1-(2-methoxyphenyl)-4-(4-(2-phthalimido)butyl)piperazine binds to and results in decreased activity of HTR1A protein] which results in decreased susceptibility to Methamphetamine |
CTD |
PMID:15213358 PMID:19747927 |
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NCBI chr 5:63,957,874...63,962,445
Ensembl chr 5:63,957,874...63,962,507
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G |
HTR1F |
5-hydroxytryptamine receptor 1F |
increases expression |
ISO |
Methamphetamine results in increased expression of HTR1F mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:87,792,706...87,993,839
Ensembl chr 3:87,792,706...87,993,839
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G |
HTR2A |
5-hydroxytryptamine receptor 2A |
multiple interactions |
ISO |
[[volinanserin binds to and results in decreased activity of HTR2A protein] which co-treated with GR 127935] results in decreased susceptibility to Methamphetamine; [Ketanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [Methamphetamine results in decreased abundance of Serotonin]; [Ketanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [Methamphetamine results in increased secretion of Corticosterone]; [volinanserin binds to and results in decreased activity of HTR2A protein] inhibits the reaction [SB 206553 results in increased susceptibility to Methamphetamine] |
CTD |
PMID:11751031 PMID:19879056 |
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NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076
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G |
HTR2B |
5-hydroxytryptamine receptor 2B |
decreases expression |
ISO |
Methamphetamine results in decreased expression of HTR2B mRNA |
CTD |
PMID:15644446 |
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NCBI chr 2:231,108,230...231,125,042
Ensembl chr 2:231,108,230...231,125,042
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G |
HTR2C |
5-hydroxytryptamine receptor 2C |
multiple interactions affects response to substance |
ISO |
[Mianserin binds to and results in decreased activity of HTR2C protein] which results in decreased susceptibility to Methamphetamine HTR2C protein affects the susceptibility to Methamphetamine |
CTD |
PMID:11751031 PMID:15213358 |
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NCBI chr X:114,584,086...114,910,061
Ensembl chr X:114,584,078...114,910,061
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G |
HTR3A |
5-hydroxytryptamine receptor 3A |
affects response to substance |
ISO |
HTR3A mRNA affects the susceptibility to Methamphetamine |
CTD |
PMID:19689456 |
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NCBI chr11:113,975,108...113,990,313
Ensembl chr11:113,975,075...113,990,313
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G |
HTR6 |
5-hydroxytryptamine receptor 6 |
increases response to substance |
EXP |
HTR6 gene SNP results in increased susceptibility to Methamphetamine |
CTD |
PMID:20705401 |
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NCBI chr 1:19,664,875...19,680,966
Ensembl chr 1:19,664,875...19,680,966
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G |
HYCC2 |
hyccin PI4KA lipid kinase complex subunit 2 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of HYCC2 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of HYCC2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:200,973,718...201,071,671
Ensembl chr 2:200,973,718...201,071,671
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G |
ICAM2 |
intercellular adhesion molecule 2 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of ICAM2 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of ICAM2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:64,002,595...64,020,633
Ensembl chr17:64,002,594...64,020,634
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G |
ICE1 |
interactor of little elongation complex ELL subunit 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ICE1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 5:5,422,677...5,490,220
Ensembl chr 5:5,420,664...5,490,220
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G |
ID1 |
inhibitor of DNA binding 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ID1 mRNA |
CTD |
PMID:25290377 |
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NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515
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G |
ID3 |
inhibitor of DNA binding 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ID3 mRNA |
CTD |
PMID:28619521 |
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NCBI chr 1:23,557,926...23,559,501
Ensembl chr 1:23,557,926...23,559,501
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G |
IDH3A |
isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha |
decreases expression |
ISO |
Methamphetamine results in decreased expression of IDH3A protein |
CTD |
PMID:19826936 |
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NCBI chr15:78,149,362...78,171,945
Ensembl chr15:78,131,498...78,171,945
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G |
IDNK |
IDNK gluconokinase |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of IDNK mRNA Methamphetamine results in decreased expression of IDNK mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:83,623,006...83,644,123
Ensembl chr 9:83,623,049...83,644,130
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G |
IER2 |
immediate early response 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of IER2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:13,150,411...13,154,911
Ensembl chr19:13,150,411...13,154,911
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G |
IFNG |
interferon gamma |
multiple interactions decreases response to substance |
ISO |
IFNG protein inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein] IFNG protein results in decreased susceptibility to Methamphetamine |
CTD |
PMID:18282668 |
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NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740
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G |
IFT80 |
intraflagellar transport 80 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of IFT80 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:160,256,986...160,399,225
Ensembl chr 3:160,256,986...160,399,880
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G |
IGFBP5 |
insulin like growth factor binding protein 5 |
multiple interactions increases expression |
ISO |
IGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of CASP3 protein]; IGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of PARP1 protein] Methamphetamine results in increased expression of IGFBP5 mRNA; Methamphetamine results in increased expression of IGFBP5 protein |
CTD |
PMID:25127757 |
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NCBI chr 2:216,672,105...216,695,549
Ensembl chr 2:216,672,105...216,695,549
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G |
IL10 |
interleukin 10 |
decreases expression increases secretion |
ISO |
Methamphetamine results in decreased expression of IL10 mRNA Methamphetamine results in increased secretion of IL10 protein |
CTD |
PMID:15644446 PMID:21276779 |
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NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541
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G |
IL18 |
interleukin 18 |
increases expression increases secretion multiple interactions |
ISO |
Methamphetamine results in increased expression of IL18 mRNA; Methamphetamine results in increased expression of IL18 protein Methamphetamine results in increased secretion of IL18 protein [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of IL18 mRNA] |
CTD |
PMID:33359793 PMID:35390362 PMID:35688268 |
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NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,253...112,164,096
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G |
IL1A |
interleukin 1 alpha |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of IL1A mRNA; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1A mRNA] |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr 2:112,773,925...112,784,493
Ensembl chr 2:112,773,925...112,784,493
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G |
IL1B |
interleukin 1 beta |
multiple interactions increases expression |
ISO EXP |
GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1B mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL1B protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of IL1B protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; Metformin inhibits the reaction [Methamphetamine results in increased expression of IL1B protein] [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of and results in increased secretion of IL1B protein]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; [SNCA protein co-treated with Methamphetamine] results in increased expression of IL1B protein; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Methamphetamine results in increased expression of IL1B protein]; Methamphetamine results in increased expression of and results in increased secretion of IL1B protein; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of IL1B protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; PELI1 protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; TICAM1 protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of IL1B protein] Methamphetamine results in increased expression of IL1B mRNA; Methamphetamine results in increased expression of IL1B protein Methamphetamine promotes the reaction [Lipopolysaccharides results in increased secretion of IL1B protein] |
CTD |
PMID:19945523 PMID:20374443 PMID:30394308 PMID:30450033 PMID:30742852 PMID:32569805 PMID:32768653 PMID:35390362 PMID:35688268 PMID:36914120 More...
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NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816
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G |
IL6 |
interleukin 6 |
multiple interactions increases expression increases secretion affects response to substance |
ISO |
[SNCA protein co-treated with Methamphetamine] results in increased expression of IL6 protein; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]; IL6 protein affects the reaction [Methamphetamine affects the expression of SLC6A4 protein]; IL6 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]]; Minocycline inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]; PELI1 protein promotes the reaction [Methamphetamine results in increased expression of IL6 protein]; TICAM1 protein promotes the reaction [Methamphetamine results in increased expression of IL6 protein] Methamphetamine results in increased expression of IL6 mRNA; Methamphetamine results in increased expression of IL6 protein IL6 protein affects the susceptibility to Methamphetamine GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL6 mRNA]; GATA4 protein affects the reaction [Methamphetamine results in increased expression of IL6 protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of IL6 protein]; margatoxin inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA]; margatoxin inhibits the reaction [Methamphetamine results in increased secretion of IL6 protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of IL6 mRNA] |
CTD |
PMID:11093760 PMID:20374443 PMID:21276779 PMID:24533129 PMID:30450033 PMID:32569805 PMID:32768653 PMID:32916201 PMID:35688268 PMID:36720452 PMID:36914120 More...
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NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002
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IMPG1 |
interphotoreceptor matrix proteoglycan 1 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of IMPG1 mRNA [Methamphetamine co-treated with SCH 23390] affects the expression of IMPG1 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr 6:75,921,114...76,072,662
Ensembl chr 6:75,921,114...76,072,678
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INF2 |
inverted formin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of INF2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr14:104,689,618...104,722,535
Ensembl chr14:104,681,146...104,722,535
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INHA |
inhibin subunit alpha |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of INHA mRNA Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of INHA mRNA] |
CTD |
PMID:19149911 |
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NCBI chr 2:219,572,310...219,575,711
Ensembl chr 2:219,569,162...219,575,711
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INPPL1 |
inositol polyphosphate phosphatase like 1 |
increases expression increases methylation |
ISO |
Methamphetamine results in increased expression of INPPL1 mRNA Methamphetamine results in increased methylation of INPPL1 promoter |
CTD |
PMID:26307267 |
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NCBI chr11:72,223,563...72,239,147
Ensembl chr11:72,223,701...72,239,147
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INSR |
insulin receptor |
increases expression decreases phosphorylation multiple interactions |
ISO EXP |
Methamphetamine results in increased expression of INSR mRNA Methamphetamine results in decreased phosphorylation of INSR protein Rosiglitazone inhibits the reaction [Methamphetamine results in decreased phosphorylation of INSR protein] |
CTD |
PMID:26307267 PMID:31270305 |
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NCBI chr19:7,112,265...7,294,414
Ensembl chr19:7,112,255...7,294,414
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IP6K1 |
inositol hexakisphosphate kinase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of IP6K1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:49,724,294...49,786,542
Ensembl chr 3:49,724,294...49,786,542
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IQCF1 |
IQ motif containing F1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of IQCF1 mRNA Methamphetamine results in increased expression of IQCF1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:51,894,876...51,903,353
Ensembl chr 3:51,894,876...51,903,353
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IRAK2 |
interleukin 1 receptor associated kinase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of IRAK2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745
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IRS1 |
insulin receptor substrate 1 |
multiple interactions decreases phosphorylation increases phosphorylation |
ISO EXP |
rosiglitazone inhibits the reaction [Methamphetamine results in increased phosphorylation of IRS1 protein] Methamphetamine results in decreased phosphorylation of IRS1 protein Rosiglitazone inhibits the reaction [Methamphetamine results in decreased phosphorylation of IRS1 protein] |
CTD |
PMID:29981415 PMID:31270305 |
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NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,312...226,799,820
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ISG20 |
interferon stimulated exonuclease gene 20 |
increases expression |
EXP |
Methamphetamine results in increased expression of ISG20 mRNA |
CTD |
PMID:25290377 |
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NCBI chr15:88,635,632...88,656,483
Ensembl chr15:88,635,670...88,656,483
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IST1 |
IST1 factor associated with ESCRT-III |
increases expression |
ISO |
Methamphetamine results in increased expression of IST1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:71,894,408...71,931,199
Ensembl chr16:71,845,996...71,931,199
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ITGA1 |
integrin subunit alpha 1 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of ITGA1 promoter |
CTD |
PMID:26307267 |
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NCBI chr 5:52,787,916...52,959,209
Ensembl chr 5:52,787,916...52,959,209
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ITGAM |
integrin subunit alpha M |
increases expression |
ISO |
Methamphetamine results in increased expression of ITGAM protein |
CTD |
PMID:32768653 |
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NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892
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ITGAV |
integrin subunit alpha V |
multiple interactions |
ISO |
[Methamphetamine co-treated with Thyroxine] results in increased expression of ITGAV protein |
CTD |
PMID:35301009 |
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NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,010...186,680,901
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ITM2A |
integral membrane protein 2A |
decreases expression increases expression |
ISO |
Methamphetamine results in decreased expression of ITM2A mRNA Methamphetamine results in increased expression of ITM2A mRNA |
CTD |
PMID:19564919 PMID:32035215 |
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NCBI chr X:79,360,384...79,367,334
Ensembl chr X:79,360,384...79,367,667
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ITPR2 |
inositol 1,4,5-trisphosphate receptor type 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ITPR2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:26,335,352...26,833,194
Ensembl chr12:26,335,352...26,833,194
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ITPRID2 |
ITPR interacting domain containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ITPRID2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:181,891,730...181,930,738
Ensembl chr 2:181,891,730...181,930,738
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IVD |
isovaleryl-CoA dehydrogenase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of IVD protein |
CTD |
PMID:19826936 |
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NCBI chr15:40,405,795...40,435,947
Ensembl chr15:40,405,485...40,435,947
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IVNS1ABP |
influenza virus NS1A binding protein |
increases expression decreases methylation |
ISO |
Methamphetamine results in increased expression of IVNS1ABP mRNA Methamphetamine results in decreased methylation of IVNS1ABP promoter |
CTD |
PMID:26307267 |
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NCBI chr 1:185,296,388...185,317,243
Ensembl chr 1:185,296,388...185,317,273
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JAK3 |
Janus kinase 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of JAK3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:17,824,782...17,847,982
Ensembl chr19:17,824,780...17,848,071
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JAML |
junction adhesion molecule like |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of JAML mRNA Methamphetamine results in decreased expression of JAML mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:118,193,725...118,225,011
Ensembl chr11:118,193,725...118,225,092
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JMJD6 |
jumonji domain containing 6, arginine demethylase and lysine hydroxylase |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of JMJD6 promoter Methamphetamine results in increased expression of JMJD6 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:76,712,836...76,726,606
Ensembl chr17:76,712,832...76,726,799
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JUN |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases activity increases expression affects response to substance multiple interactions |
EXP ISO |
Methamphetamine results in increased activity of JUN protein Methamphetamine results in increased expression of JUN mRNA Methamphetamine results in increased expression of JUN protein JUN protein affects the susceptibility to Methamphetamine JUN protein affects the reaction [Methamphetamine results in increased activity of CASP3 protein] |
CTD |
PMID:10336889 PMID:11746378 PMID:12391261 PMID:15644446 PMID:19564919 |
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NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048
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G |
JUNB |
JunB proto-oncogene, AP-1 transcription factor subunit |
multiple interactions decreases expression increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of JUNB mRNA Methamphetamine results in decreased expression of JUNB mRNA Methamphetamine results in increased expression of JUNB mRNA |
CTD |
PMID:15644446 PMID:19564919 PMID:32035215 |
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NCBI chr19:12,791,486...12,793,315
Ensembl chr19:12,791,486...12,793,315
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G |
KANK3 |
KN motif and ankyrin repeat domains 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of KANK3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:8,322,584...8,343,262
Ensembl chr19:8,322,584...8,343,262
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G |
KAT2A |
lysine acetyltransferase 2A |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of KAT2A promoter Methamphetamine results in increased expression of KAT2A mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:42,113,111...42,121,367
Ensembl chr17:42,113,111...42,121,367
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G |
KAT6A |
lysine acetyltransferase 6A |
increases expression |
ISO |
Methamphetamine results in increased expression of KAT6A mRNA |
CTD |
PMID:26307267 |
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NCBI chr 8:41,929,479...42,051,987
Ensembl chr 8:41,929,479...42,051,994
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G |
KCNA3 |
potassium voltage-gated channel subfamily A member 3 |
multiple interactions increases expression |
ISO |
margatoxin inhibits the reaction [Methamphetamine results in increased expression of KCNA3 mRNA]; margatoxin inhibits the reaction [Methamphetamine results in increased expression of KCNA3 protein] Methamphetamine results in increased expression of KCNA3 mRNA; Methamphetamine results in increased expression of KCNA3 protein |
CTD |
PMID:24533129 |
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NCBI chr 1:110,653,560...110,674,940
Ensembl chr 1:110,653,560...110,674,940
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G |
KCNB1 |
potassium voltage-gated channel subfamily B member 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of KCNB1 mRNA Methamphetamine results in increased expression of KCNB1 protein 2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate inhibits the reaction [Methamphetamine results in increased expression of KCNB1 protein]; pyrazolanthrone inhibits the reaction [Methamphetamine results in increased expression of KCNB1 protein]; SB 203580 inhibits the reaction [Methamphetamine results in increased expression of KCNB1 protein] |
CTD |
PMID:26307267 PMID:29297590 |
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NCBI chr20:49,363,877...49,483,362
Ensembl chr20:49,293,394...49,484,297
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KCNE1 |
potassium voltage-gated channel subfamily E regulatory subunit 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of KCNE1 mRNA |
CTD |
PMID:15644446 |
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NCBI chr21:34,446,688...34,512,210
Ensembl chr21:34,446,688...34,512,214
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G |
KCNIP2 |
potassium voltage-gated channel interacting protein 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of KCNIP2 mRNA |
CTD |
PMID:35863504 |
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NCBI chr10:101,825,974...101,843,800
Ensembl chr10:101,825,974...101,843,920
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G |
KCNJ14 |
potassium inwardly rectifying channel subfamily J member 14 |
increases expression |
ISO |
Methamphetamine results in increased expression of KCNJ14 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:48,455,574...48,466,980
Ensembl chr19:48,455,574...48,466,980
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G |
KCNJ3 |
potassium inwardly rectifying channel subfamily J member 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of KCNJ3 mRNA |
CTD |
PMID:21886566 |
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NCBI chr 2:154,698,695...154,858,354
Ensembl chr 2:154,697,855...154,858,354
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G |
KCNJ4 |
potassium inwardly rectifying channel subfamily J member 4 |
multiple interactions decreases expression |
ISO |
Fluoxetine inhibits the reaction [Methamphetamine results in decreased expression of KCNJ4 mRNA] |
CTD |
PMID:21886566 |
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NCBI chr22:38,426,327...38,455,199
Ensembl chr22:38,426,327...38,455,199
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G |
KCNJ5 |
potassium inwardly rectifying channel subfamily J member 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of KCNJ5 mRNA |
CTD |
PMID:15644446 |
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NCBI chr11:128,891,356...128,921,163
Ensembl chr11:128,891,356...128,921,163
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G |
KCNJ6 |
potassium inwardly rectifying channel subfamily J member 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of KCNJ6 mRNA |
CTD |
PMID:21886566 |
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NCBI chr21:37,607,373...37,916,457
Ensembl chr21:37,607,373...38,121,345
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G |
KCNJ9 |
potassium inwardly rectifying channel subfamily J member 9 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of KCNJ9 mRNA |
CTD |
PMID:21886566 |
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NCBI chr 1:160,081,538...160,090,563
Ensembl chr 1:160,081,538...160,090,563
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G |
KCTD14 |
potassium channel tetramerization domain containing 14 |
increases expression |
ISO |
Methamphetamine results in increased expression of KCTD14 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:78,015,715...78,046,191
Ensembl chr11:78,015,715...78,046,191
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G |
KDM6A |
lysine demethylase 6A |
increases expression |
ISO |
Methamphetamine results in increased expression of KDM6A mRNA |
CTD |
PMID:26307267 |
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NCBI chr X:44,873,188...45,112,779
Ensembl chr X:44,873,188...45,112,779
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G |
KDM6B |
lysine demethylase 6B |
increases expression |
ISO |
Methamphetamine results in increased expression of KDM6B mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr17:7,834,217...7,854,796
Ensembl chr17:7,834,217...7,854,796
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G |
KIAA1217 |
KIAA1217 |
increases expression |
ISO |
Methamphetamine results in increased expression of ETL4 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:23,694,727...24,547,843
Ensembl chr10:23,694,746...24,547,848
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G |
KIF15 |
kinesin family member 15 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of KIF15 mRNA Methamphetamine results in decreased expression of KIF15 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:44,761,794...44,868,687
Ensembl chr 3:44,761,721...44,873,376
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G |
KIF17 |
kinesin family member 17 |
increases expression |
ISO |
Methamphetamine results in increased expression of KIF17 protein |
CTD |
PMID:17105907 |
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NCBI chr 1:20,661,630...20,718,007
Ensembl chr 1:20,664,014...20,718,017
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KIF20A |
kinesin family member 20A |
decreases expression |
EXP ISO |
Methamphetamine results in decreased expression of KIF20A mRNA |
CTD |
PMID:25290377 PMID:28341135 |
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NCBI chr 5:138,179,112...138,187,723
Ensembl chr 5:138,178,719...138,187,723
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KIFBP |
kinesin family binding protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of KIFBP mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:68,988,803...69,016,982
Ensembl chr10:68,988,803...69,043,544
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G |
KIFC1 |
kinesin family member C1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of KIFC1 mRNA |
CTD |
PMID:25290377 |
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NCBI chr 6:33,391,461...33,409,896
Ensembl chr 6:33,391,823...33,409,896
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G |
KLF10 |
KLF transcription factor 10 |
increases expression |
ISO |
Methamphetamine results in increased expression of KLF10 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 8:102,648,784...102,655,725
Ensembl chr 8:102,648,784...102,655,725
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G |
KLF15 |
KLF transcription factor 15 |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of KLF15 protein Methamphetamine results in decreased expression of KLF15 mRNA |
CTD |
PMID:35863504 PMID:36914120 |
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NCBI chr 3:126,288,125...126,357,408
Ensembl chr 3:126,342,635...126,357,408
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G |
KLF5 |
KLF transcription factor 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of KLF5 mRNA |
CTD |
PMID:19564919 |
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NCBI chr13:73,054,976...73,077,538
Ensembl chr13:73,054,976...73,077,541
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KLF6 |
KLF transcription factor 6 |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of KLF6 mRNA Methamphetamine results in decreased expression of KLF6 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281
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G |
KLF7 |
KLF transcription factor 7 |
increases expression |
ISO |
Methamphetamine results in increased expression of KLF7 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:207,074,137...207,173,851
Ensembl chr 2:207,074,137...207,173,856
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G |
KLHDC9 |
kelch domain containing 9 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of KLHDC9 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:161,098,361...161,100,346
Ensembl chr 1:161,098,361...161,100,346
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G |
KLHL15 |
kelch like family member 15 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of KLHL15 mRNA Methamphetamine results in increased expression of KLHL15 mRNA |
CTD |
PMID:19564919 |
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NCBI chr X:23,983,720...24,027,186
Ensembl chr X:23,983,716...24,027,186
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G |
KLHL21 |
kelch like family member 21 |
increases expression |
ISO |
Methamphetamine results in increased expression of KLHL21 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 1:6,590,724...6,602,869
Ensembl chr 1:6,590,724...6,614,607
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G |
KLHL22 |
kelch like family member 22 |
increases expression |
ISO |
Methamphetamine results in increased expression of KLHL22 mRNA |
CTD |
PMID:26307267 |
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NCBI chr22:20,441,519...20,495,795
Ensembl chr22:20,441,519...20,495,844
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G |
KMT2E |
lysine methyltransferase 2E (inactive) |
increases expression |
ISO |
Methamphetamine results in increased expression of KMT2E mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:105,014,205...105,115,019
Ensembl chr 7:104,940,943...105,115,019
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G |
KNDC1 |
kinase non-catalytic C-lobe domain containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of KNDC1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:133,160,219...133,226,412
Ensembl chr10:133,160,219...133,226,412
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G |
KNSTRN |
kinetochore localized astrin (SPAG5) binding protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of KNSTRN mRNA |
CTD |
PMID:28341135 |
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NCBI chr15:40,382,721...40,394,288
Ensembl chr15:40,382,721...40,394,288
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G |
KNTC1 |
kinetochore associated 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of KNTC1 mRNA |
CTD |
PMID:19564919 PMID:28341135 |
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NCBI chr12:122,527,249...122,626,396
Ensembl chr12:122,527,246...122,626,396
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G |
KPNA4 |
karyopherin subunit alpha 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of KPNA4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:160,495,007...160,565,571
Ensembl chr 3:160,495,007...160,565,571
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G |
KRT14 |
keratin 14 |
increases expression |
EXP |
Methamphetamine results in increased expression of KRT14 mRNA |
CTD |
PMID:25290377 |
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NCBI chr17:41,582,279...41,586,895
Ensembl chr17:41,582,279...41,586,895
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G |
KRT7 |
keratin 7 |
affects expression multiple interactions |
ISO |
Methamphetamine affects the expression of KRT7 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of KRT7 mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186
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G |
KRT80 |
keratin 80 |
increases expression |
ISO |
Methamphetamine results in increased expression of KRT80 mRNA |
CTD |
PMID:28341135 |
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NCBI chr12:52,168,996...52,192,014
Ensembl chr12:52,168,996...52,192,014
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G |
KYNU |
kynureninase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of KYNU mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
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G |
L3MBTL1 |
L3MBTL histone methyl-lysine binding protein 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of L3MBTL1 mRNA Methamphetamine results in decreased expression of L3MBTL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:43,507,697...43,550,954
Ensembl chr20:43,489,442...43,550,954
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G |
LACTB |
lactamase beta |
increases expression |
ISO |
Methamphetamine results in increased expression of LACTB mRNA |
CTD |
PMID:19149911 |
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NCBI chr15:63,121,861...63,142,061
Ensembl chr15:63,121,833...63,142,061
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G |
LAMB2 |
laminin subunit beta 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of LAMB2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:49,121,114...49,133,050
Ensembl chr 3:49,121,114...49,133,118
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G |
LAMP1 |
lysosomal associated membrane protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of LAMP1 mRNA; Methamphetamine results in increased expression of LAMP1 protein |
CTD |
PMID:23933405 PMID:34374793 PMID:35643125 |
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NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672
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G |
LAMP2 |
lysosomal associated membrane protein 2 |
affects localization increases expression |
ISO |
Methamphetamine affects the localization of LAMP2 protein Methamphetamine results in increased expression of LAMP2 mRNA; Methamphetamine results in increased expression of LAMP2 protein |
CTD |
PMID:17105920 PMID:35643125 |
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NCBI chr X:120,426,148...120,469,349
Ensembl chr X:120,426,148...120,469,365
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G |
LARGE1 |
LARGE xylosyl- and glucuronyltransferase 1 |
affects response to substance |
EXP |
LARGE1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr22:33,066,663...33,922,824
Ensembl chr22:33,162,226...33,922,841
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G |
LCN1 |
lipocalin 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of LCN3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:135,521,440...135,526,540
Ensembl chr 9:135,521,438...135,526,540
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G |
LDB1 |
LIM domain binding 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of LDB1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:102,102,088...102,121,442
Ensembl chr10:102,106,489...102,120,368
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G |
LDHD |
lactate dehydrogenase D |
increases expression |
ISO |
Methamphetamine results in increased expression of LDHD mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:75,111,864...75,116,780
Ensembl chr16:75,111,860...75,116,780
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G |
LGALS9 |
galectin 9 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LGALS9 mRNA Methamphetamine results in decreased expression of LGALS9 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:27,631,188...27,649,560
Ensembl chr17:27,629,798...27,649,560
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G |
LGI3 |
leucine rich repeat LGI family member 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of LGI3 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:22,146,830...22,156,806
Ensembl chr 8:22,146,830...22,157,084
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G |
LGR4 |
leucine rich repeat containing G protein-coupled receptor 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of LGR4 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:27,365,961...27,472,790
Ensembl chr11:27,365,961...27,472,790
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G |
LIME1 |
Lck interacting transmembrane adaptor 1 |
increases expression decreases methylation |
ISO |
Methamphetamine results in increased expression of LIME1 mRNA Methamphetamine results in decreased methylation of LIME1 promoter |
CTD |
PMID:26307267 |
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NCBI chr20:63,735,701...63,739,103
Ensembl chr20:63,736,283...63,739,103
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G |
LIMS2 |
LIM zinc finger domain containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of LIMS2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:127,638,426...127,681,786
Ensembl chr 2:127,638,381...127,681,786
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G |
LIN54 |
lin-54 DREAM MuvB core complex component |
decreases expression |
ISO |
Methamphetamine results in decreased expression of LIN54 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 4:82,924,603...83,012,941
Ensembl chr 4:82,909,973...83,012,926
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G |
LINGO2 |
leucine rich repeat and Ig domain containing 2 |
affects response to substance |
EXP |
LINGO2 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 9:27,937,617...29,213,601
Ensembl chr 9:27,937,617...29,213,601
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G |
LIPE |
lipase E, hormone sensitive type |
increases expression |
ISO |
Methamphetamine results in increased expression of LIPE mRNA |
CTD |
PMID:35863504 |
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NCBI chr19:42,401,514...42,427,388
Ensembl chr19:42,401,514...42,427,388
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G |
LLPH |
LLP homolog, long-term synaptic facilitation factor |
increases methylation |
ISO |
Methamphetamine results in increased methylation of LLPH promoter |
CTD |
PMID:26307267 |
|
NCBI chr12:66,116,555...66,130,750
Ensembl chr12:66,116,555...66,130,750
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G |
LMF2 |
lipase maturation factor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of LMF2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr22:50,502,949...50,507,702
Ensembl chr22:50,502,949...50,507,702
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G |
LMO7 |
LIM domain 7 |
increases expression |
ISO |
Methamphetamine results in increased expression of LMO7 mRNA |
CTD |
PMID:26307267 |
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NCBI chr13:75,620,434...75,859,870
Ensembl chr13:75,620,434...75,859,870
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G |
LMTK3 |
lemur tyrosine kinase 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of LMTK3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr19:48,485,271...48,513,680
Ensembl chr19:48,485,271...48,513,935
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G |
LPXN |
leupaxin |
decreases expression |
ISO |
Methamphetamine results in decreased expression of LPXN mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:58,526,871...58,578,891
Ensembl chr11:58,526,871...58,578,220
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G |
LRATD1 |
LRAT domain containing 1 |
affects expression |
ISO |
Methamphetamine affects the expression of LRATD1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:14,632,717...14,651,916
Ensembl chr 2:14,632,700...14,650,814
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G |
LRIG3 |
leucine rich repeats and immunoglobulin like domains 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of LRIG3 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr12:58,872,155...58,920,504
Ensembl chr12:58,872,149...58,920,504
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G |
LRP1 |
LDL receptor related protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of LRP1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:57,128,483...57,213,361
Ensembl chr12:57,128,483...57,213,361
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G |
LRRC28 |
leucine rich repeat containing 28 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of LRRC28 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of LRRC28 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr15:99,251,481...99,390,729
Ensembl chr15:99,251,362...99,390,729
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G |
LRRC8C |
leucine rich repeat containing 8 VRAC subunit C |
increases expression |
ISO |
Methamphetamine results in increased expression of LRRC8C mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:89,615,824...89,719,533
Ensembl chr 1:89,633,072...89,769,903
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G |
LRRFIP1 |
LRR binding FLII interacting protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of LRRFIP1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:237,627,587...237,781,643
Ensembl chr 2:237,627,587...237,813,682
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G |
LSP1 |
lymphocyte specific protein 1 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of LSP1 promoter |
CTD |
PMID:26307267 |
|
NCBI chr11:1,853,084...1,892,263
Ensembl chr11:1,850,904...1,892,267
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G |
LTBP1 |
latent transforming growth factor beta binding protein 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LTBP1 mRNA Methamphetamine results in decreased expression of LTBP1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:32,946,953...33,399,509
Ensembl chr 2:32,946,953...33,399,509
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G |
LTBP4 |
latent transforming growth factor beta binding protein 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of LTBP4 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr19:40,593,166...40,629,820
Ensembl chr19:40,592,883...40,629,818
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G |
LTC4S |
leukotriene C4 synthase |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of LTC4S mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of LTC4S mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:179,793,986...179,796,647
Ensembl chr 5:179,793,980...179,796,647
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G |
LTK |
leukocyte receptor tyrosine kinase |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of LTK mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of LTK mRNA |
CTD |
PMID:19564919 |
|
NCBI chr15:41,503,637...41,513,827
Ensembl chr15:41,503,637...41,513,887
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G |
LUC7L2 |
LUC7 like 2, pre-mRNA splicing factor |
increases expression |
ISO |
Methamphetamine results in increased expression of LUC7L2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:139,340,472...139,423,454
Ensembl chr 7:139,340,359...139,423,457
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G |
LUM |
lumican |
decreases expression |
ISO |
Methamphetamine results in decreased expression of LUM mRNA |
CTD |
PMID:36914120 |
|
NCBI chr12:91,102,629...91,111,494
Ensembl chr12:91,102,629...91,111,494
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G |
LURAP1 |
leucine rich adaptor protein 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LURAP1 mRNA Methamphetamine results in decreased expression of LURAP1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:46,203,334...46,221,256
Ensembl chr 1:46,203,334...46,221,256
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G |
LY96 |
lymphocyte antigen 96 |
increases expression |
EXP |
Methamphetamine results in increased expression of LY96 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr 8:73,991,392...74,099,857
Ensembl chr 8:73,991,392...74,029,079
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G |
LYPD1 |
LY6/PLAUR domain containing 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of LYPD1 mRNA |
CTD |
PMID:28619521 |
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NCBI chr 2:132,643,286...132,671,526
Ensembl chr 2:132,643,286...132,671,579
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G |
LYRM9 |
LYR motif containing 9 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of LYRM9 mRNA Methamphetamine results in decreased expression of LYRM9 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:27,878,358...27,893,365
Ensembl chr17:27,878,314...27,894,752
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G |
LZIC |
leucine zipper and CTNNBIP1 domain containing |
increases expression |
ISO |
Methamphetamine results in increased expression of LZIC protein |
CTD |
PMID:19826936 |
|
NCBI chr 1:9,922,118...9,943,391
Ensembl chr 1:9,922,113...9,943,407
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G |
LZTS2 |
leucine zipper tumor suppressor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of LZTS2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:100,996,588...101,007,833
Ensembl chr10:100,996,618...101,007,836
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G |
MACF1 |
microtubule actin crosslinking factor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of MACF1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:39,084,167...39,487,138
Ensembl chr 1:39,081,316...39,487,177
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G |
MAFF |
MAF bZIP transcription factor F |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of MAFF mRNA Methamphetamine results in increased expression of MAFF mRNA |
CTD |
PMID:19564919 |
|
NCBI chr22:38,201,994...38,216,511
Ensembl chr22:38,200,767...38,216,507
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G |
MAFK |
MAF bZIP transcription factor K |
increases expression |
ISO |
Methamphetamine results in increased expression of MAFK mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:1,530,702...1,543,043
Ensembl chr 7:1,530,702...1,543,043
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G |
MAGEA4 |
MAGE family member A4 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MAGEA4 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr X:151,912,474...151,925,170
Ensembl chr X:151,912,495...151,925,171
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G |
MAGEB3 |
MAGE family member B3 |
increases expression |
ISO |
Methamphetamine results in increased expression of MAGEB3 mRNA |
CTD |
PMID:28341135 |
|
NCBI chr X:30,230,657...30,237,495
Ensembl chr X:30,230,657...30,237,495
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G |
MAGI1 |
membrane associated guanylate kinase, WW and PDZ domain containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of MAGI1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 3:65,353,526...66,038,918
Ensembl chr 3:65,353,525...66,038,918
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G |
MANF |
mesencephalic astrocyte derived neurotrophic factor |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of MANF mRNA SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of MANF mRNA] |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr 3:51,385,291...51,389,397
Ensembl chr 3:51,385,291...51,389,397
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G |
MAOA |
monoamine oxidase A |
increases expression multiple interactions affects response to substance |
ISO |
Methamphetamine results in increased expression of MAOA mRNA Methamphetamine results in increased expression of MAOA protein [Clorgyline results in decreased activity of MAOA protein] which results in increased susceptibility to Methamphetamine MAOA protein affects the susceptibility to Methamphetamine |
CTD |
PMID:1905457 PMID:19149911 PMID:32035215 PMID:33359793 |
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NCBI chr X:43,655,006...43,746,817
Ensembl chr X:43,654,907...43,746,817
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G |
MAOB |
monoamine oxidase B |
affects response to substance multiple interactions |
ISO |
MAOB protein affects the susceptibility to Methamphetamine [Selegiline results in decreased activity of MAOB protein] which results in increased susceptibility to Methamphetamine |
CTD |
PMID:1905457 |
|
NCBI chr X:43,766,610...43,882,450
Ensembl chr X:43,766,610...43,882,450
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G |
MAP1A |
microtubule associated protein 1A |
increases expression |
ISO |
Methamphetamine results in increased expression of MAP1A protein |
CTD |
PMID:19826936 |
|
NCBI chr15:43,510,954...43,531,611
Ensembl chr15:43,510,958...43,531,620
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G |
MAP1LC3B |
microtubule associated protein 1 light chain 3 beta |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of MAP1LC3B mRNA NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of MAP1LC3B protein]; sulforaphane inhibits the reaction [Methamphetamine results in increased expression of MAP1LC3B protein] Methamphetamine results in increased lipidation of and affects the localization of MAP1LC3B protein; STX17 protein inhibits the reaction [Methamphetamine results in increased lipidation of MAP1LC3B protein] |
CTD |
PMID:34374793 PMID:37567421 |
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NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779
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G |
MAP2 |
microtubule associated protein 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MAP2 mRNA; Methamphetamine results in decreased expression of MAP2 protein |
CTD |
PMID:17407499 |
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NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147
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G |
MAP2K1 |
mitogen-activated protein kinase kinase 1 |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of MAP2K1 protein Methamphetamine results in decreased expression of MAP2K1 protein |
CTD |
PMID:16192988 PMID:19826936 |
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NCBI chr15:66,386,912...66,491,544
Ensembl chr15:66,386,837...66,491,656
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G |
MAP2K3 |
mitogen-activated protein kinase kinase 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of MAP2K3 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,232
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G |
MAP2K5 |
mitogen-activated protein kinase kinase 5 |
affects response to substance |
EXP |
MAP2K5 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr15:67,542,703...67,807,114
Ensembl chr15:67,542,703...67,807,117
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G |
MAP2K7 |
mitogen-activated protein kinase kinase 7 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MAP2K7 protein |
CTD |
PMID:16192988 |
|
NCBI chr19:7,903,877...7,914,478
Ensembl chr19:7,903,843...7,914,478
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G |
MAP3K7 |
mitogen-activated protein kinase kinase kinase 7 |
increases expression |
ISO |
Methamphetamine results in increased expression of MAP3K7 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086
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G |
MAP4 |
microtubule associated protein 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of MAP4 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 3:47,850,695...48,088,848
Ensembl chr 3:47,850,690...48,089,272
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G |
MAP4K2 |
mitogen-activated protein kinase kinase kinase kinase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of MAP4K2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:64,784,918...64,803,214
Ensembl chr11:64,784,918...64,803,241
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G |
MAPK1 |
mitogen-activated protein kinase 1 |
decreases expression decreases phosphorylation affects phosphorylation multiple interactions increases expression |
ISO EXP |
Methamphetamine results in decreased expression of MAPK1 protein Methamphetamine results in decreased phosphorylation of MAPK1 protein Methamphetamine affects the phosphorylation of MAPK1 protein Rosiglitazone affects the reaction [Methamphetamine affects the phosphorylation of MAPK1 protein] Methamphetamine results in increased expression of MAPK1 mRNA |
CTD |
PMID:16192988 PMID:19149911 PMID:31270305 PMID:32768653 |
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NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680
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G |
MAPK11 |
mitogen-activated protein kinase 11 |
increases expression |
ISO |
Methamphetamine results in increased expression of MAPK11 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr22:50,263,713...50,270,380
Ensembl chr22:50,263,713...50,270,767
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G |
MAPK3 |
mitogen-activated protein kinase 3 |
multiple interactions decreases phosphorylation affects phosphorylation |
EXP ISO |
Rosiglitazone affects the reaction [Methamphetamine affects the phosphorylation of MAPK3 protein] Methamphetamine results in decreased phosphorylation of MAPK3 protein |
CTD |
PMID:31270305 PMID:32768653 |
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NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506
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G |
MAPK8 |
mitogen-activated protein kinase 8 |
increases phosphorylation |
ISO |
Methamphetamine results in increased phosphorylation of MAPK8 protein |
CTD |
PMID:32768653 |
|
NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360
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G |
MAPK8IP3 |
mitogen-activated protein kinase 8 interacting protein 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of MAPK8IP3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr16:1,706,195...1,770,351
Ensembl chr16:1,706,166...1,770,351
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G |
MAPK9 |
mitogen-activated protein kinase 9 |
increases phosphorylation |
ISO |
Methamphetamine results in increased phosphorylation of MAPK9 protein |
CTD |
PMID:32768653 |
|
NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
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G |
MAPT |
microtubule associated protein tau |
multiple interactions increases phosphorylation increases expression decreases expression |
ISO EXP |
(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of MAPT mRNA]; MAPT protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]; Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein; Rosiglitazone inhibits the reaction [Methamphetamine results in increased phosphorylation of MAPT protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MAPT protein modified form]; SNCA protein affects the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein]; TWS 119 inhibits the reaction [Methamphetamine results in increased phosphorylation of MAPT protein] CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of MAPT protein]; Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein; Rosiglitazone inhibits the reaction [Methamphetamine results in increased phosphorylation of MAPT protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein] Methamphetamine results in increased expression of MAPT mRNA; Methamphetamine results in increased expression of MAPT protein modified form |
CTD |
PMID:11756511 PMID:26307267 PMID:29705343 PMID:29981415 PMID:31270305 PMID:31783120 PMID:32278788 More...
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NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334
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G |
MARVELD1 |
MARVEL domain containing 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MARVELD1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:97,713,730...97,718,150
Ensembl chr10:97,713,173...97,718,150
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G |
MAST2 |
microtubule associated serine/threonine kinase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of MAST2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:45,803,612...46,036,122
Ensembl chr 1:45,786,987...46,036,122
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MASTL |
microtubule associated serine/threonine kinase like |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of MASTL mRNA [Methamphetamine co-treated with SCH 23390] affects the expression of MASTL mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:27,154,479...27,187,953
Ensembl chr10:27,154,824...27,187,953
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MAU2 |
MAU2 sister chromatid cohesion factor |
increases expression |
ISO |
Methamphetamine results in increased expression of MAU2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:19,320,829...19,358,754
Ensembl chr19:19,320,829...19,358,754
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MAVS |
mitochondrial antiviral signaling protein |
increases expression |
ISO |
Methamphetamine results in increased expression of MAVS mRNA |
CTD |
PMID:36914120 |
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NCBI chr20:3,846,834...3,876,118
Ensembl chr20:3,846,799...3,876,123
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MBP |
myelin basic protein |
affects expression multiple interactions decreases expression |
ISO |
Methamphetamine affects the expression of MBP protein SNCA protein affects the reaction [Methamphetamine results in decreased expression of MBP protein] |
CTD |
PMID:16842764 PMID:17262233 PMID:34562559 |
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NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683
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MC4R |
melanocortin 4 receptor |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of MC4R mRNA Methamphetamine results in increased expression of MC4R mRNA |
CTD |
PMID:19564919 |
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NCBI chr18:60,371,062...60,372,775
Ensembl chr18:60,371,062...60,372,775
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MCAM |
melanoma cell adhesion molecule |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MCAM mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:119,308,529...119,317,130
Ensembl chr11:119,308,529...119,321,521
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MCC |
MCC regulator of WNT signaling pathway |
increases expression |
ISO |
Methamphetamine results in increased expression of MCC mRNA |
CTD |
PMID:28341135 |
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NCBI chr 5:113,022,106...113,488,453
Ensembl chr 5:113,022,106...113,488,823
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MCL1 |
MCL1 apoptosis regulator, BCL2 family member |
increases expression |
ISO |
Methamphetamine results in increased expression of MCL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:150,574,558...150,579,610
Ensembl chr 1:150,560,895...150,579,738
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MCM10 |
minichromosome maintenance 10 replication initiation factor |
decreases expression |
EXP |
Methamphetamine results in decreased expression of MCM10 mRNA |
CTD |
PMID:25290377 |
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NCBI chr10:13,161,558...13,211,110
Ensembl chr10:13,161,558...13,211,110
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G |
MCM8 |
minichromosome maintenance 8 homologous recombination repair factor |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of MCM8 mRNA Methamphetamine results in decreased expression of MCM8 mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:5,950,652...5,998,977
Ensembl chr20:5,950,652...5,998,977
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MCOLN3 |
mucolipin TRP cation channel 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of MCOLN3 mRNA |
CTD |
PMID:28619521 |
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NCBI chr 1:85,018,082...85,048,500
Ensembl chr 1:85,018,082...85,048,500
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G |
MED29 |
mediator complex subunit 29 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MED29 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:39,391,378...39,400,641
Ensembl chr19:39,391,303...39,400,641
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G |
MELTF |
melanotransferrin |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MELTF mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:197,001,740...197,029,817
Ensembl chr 3:196,980,590...197,029,835
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G |
METRNL |
meteorin like, glial cell differentiation regulator |
increases expression |
ISO |
Methamphetamine results in increased expression of METRNL mRNA |
CTD |
PMID:36914120 |
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NCBI chr17:83,079,609...83,095,122
Ensembl chr17:83,079,609...83,095,122
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G |
METTL8 |
methyltransferase 8, tRNA N3-cytidine |
decreases expression |
ISO |
Methamphetamine results in decreased expression of METTL8 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:171,315,746...171,434,772
Ensembl chr 2:171,315,746...171,434,802
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G |
MFAP4 |
microfibril associated protein 4 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MFAP4 mRNA |
CTD |
PMID:36914120 |
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NCBI chr17:19,383,445...19,387,190
Ensembl chr17:19,383,442...19,387,190
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G |
MFSD10 |
major facilitator superfamily domain containing 10 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of MFSD10 mRNA Methamphetamine results in decreased expression of MFSD10 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:2,930,567...2,934,825
Ensembl chr 4:2,930,561...2,934,834
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MIA2 |
MIA SH3 domain ER export factor 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MIA2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr14:39,233,915...39,388,522
Ensembl chr14:39,230,231...39,388,513
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G |
MICAL1 |
microtubule associated monooxygenase, calponin and LIM domain containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of MICAL1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:109,444,062...109,465,968
Ensembl chr 6:109,444,062...109,465,968
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MICAL3 |
microtubule associated monooxygenase, calponin and LIM domain containing 3 |
increases expression increases methylation |
ISO |
Methamphetamine results in increased expression of MICAL3 mRNA Methamphetamine results in increased methylation of MICAL3 promoter |
CTD |
PMID:26307267 |
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NCBI chr22:17,787,649...18,024,561
Ensembl chr22:17,787,649...18,024,561
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MICALL1 |
MICAL like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of MICALL1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr22:37,906,297...37,942,822
Ensembl chr22:37,905,657...37,942,822
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MID1IP1 |
MID1 interacting protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of MID1IP1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr X:38,801,459...38,806,532
Ensembl chr X:38,801,440...38,806,537
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G |
MIF |
macrophage migration inhibitory factor |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MIF mRNA |
CTD |
PMID:19149911 |
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NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227
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G |
MIGA2 |
mitoguardin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of MIGA2 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 9:129,036,626...129,072,082
Ensembl chr 9:129,036,621...129,072,082
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G |
MINDY2 |
MINDY lysine 48 deubiquitinase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of MINDY2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr15:58,771,302...58,861,900
Ensembl chr15:58,771,192...58,861,900
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G |
MIR143 |
microRNA 143 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of MIR143 mRNA Methamphetamine promotes the reaction [NFKB1 protein binds to MIR143 promoter]; MIR143 mRNA affects the reaction [Methamphetamine results in increased cleavage of CASP1 protein]; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of IL1B protein]; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of NLRP3 protein]; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of NOS2 protein]; NFKB1 protein affects the reaction [Methamphetamine results in decreased expression of MIR143 mRNA] |
CTD |
PMID:30394308 |
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NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023
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G |
MIR150 |
microRNA 150 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MIR150 mRNA |
CTD |
PMID:35863504 |
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NCBI chr19:49,500,785...49,500,868
Ensembl chr19:49,500,785...49,500,868
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MIR320A |
microRNA 320a |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MIR320A mRNA |
CTD |
PMID:35863504 |
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NCBI chr 8:22,244,966...22,245,037
Ensembl chr 8:22,244,962...22,245,043
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G |
MIR326 |
microRNA 326 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MIR326 mRNA |
CTD |
PMID:35863504 |
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NCBI chr11:75,335,092...75,335,186
Ensembl chr11:75,335,092...75,335,186
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G |
MIR331 |
microRNA 331 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MIR331 mRNA |
CTD |
PMID:35863504 |
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NCBI chr12:95,308,420...95,308,513
Ensembl chr12:95,308,420...95,308,513
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G |
MIR339 |
microRNA 339 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MIR339 mRNA |
CTD |
PMID:35863504 |
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NCBI chr 7:1,022,933...1,023,026
Ensembl chr 7:1,022,933...1,023,026
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G |
MIR423 |
microRNA 423 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MIR423 mRNA |
CTD |
PMID:35863504 |
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NCBI chr17:30,117,079...30,117,172
Ensembl chr17:30,117,079...30,117,172
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G |
MKI67 |
marker of proliferation Ki-67 |
decreases expression |
EXP ISO |
Methamphetamine results in decreased expression of MKI67 mRNA |
CTD |
PMID:25290377 PMID:28619521 |
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NCBI chr10:128,096,659...128,126,423
Ensembl chr10:128,096,659...128,126,423
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G |
MLLT10 |
MLLT10 histone lysine methyltransferase DOT1L cofactor |
increases expression |
ISO |
Methamphetamine results in increased expression of MLLT10 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:21,533,756...21,743,630
Ensembl chr10:21,524,646...21,743,630
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G |
MLLT6 |
MLLT6, PHD finger containing |
increases expression |
ISO |
Methamphetamine results in increased expression of MLLT6 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:38,705,273...38,729,795
Ensembl chr17:38,705,273...38,729,795
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G |
MMP2 |
matrix metallopeptidase 2 |
increases activity decreases expression increases response to substance |
ISO |
Methamphetamine results in increased activity of MMP2 protein Methamphetamine results in decreased expression of MMP2 mRNA MMP2 protein results in increased susceptibility to Methamphetamine |
CTD |
PMID:18198472 PMID:36914120 |
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NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691
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G |
MMP9 |
matrix metallopeptidase 9 |
multiple interactions increases response to substance increases expression increases activity |
EXP ISO |
[HIV Envelope Protein gp120 co-treated with Methamphetamine] promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP9 mRNA]; [HIV Envelope Protein gp120 co-treated with Methamphetamine] promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of and results in increased activity of MMP9 protein]; Methamphetamine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased expression of MMP9 mRNA]; Methamphetamine promotes the reaction [lipopolysaccharide, E. coli O26-B6 results in increased secretion of MMP9 protein] MMP9 protein results in increased susceptibility to Methamphetamine Methamphetamine results in increased expression of MMP9 Methamphetamine results in increased activity of MMP9 protein |
CTD |
PMID:18198472 PMID:18766021 PMID:21425912 |
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NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561
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G |
MN1 |
MN1 proto-oncogene, transcriptional regulator |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of MN1 mRNA Methamphetamine results in decreased expression of MN1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr22:27,748,277...27,801,756
Ensembl chr22:27,748,277...27,801,756
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G |
MOV10 |
Mov10 RNA helicase |
increases expression |
ISO |
Methamphetamine results in increased expression of MOV10 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:112,674,439...112,700,739
Ensembl chr 1:112,673,141...112,700,756
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G |
MPG |
N-methylpurine DNA glycosylase |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of MPG mRNA Methamphetamine results in decreased expression of MPG mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:77,007...85,846
Ensembl chr16:77,007...85,851
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G |
MPPE1 |
metallophosphoesterase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MPPE1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr18:11,882,622...11,908,317
Ensembl chr18:11,882,622...11,908,366
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G |
MPRIP |
myosin phosphatase Rho interacting protein |
increases expression |
ISO |
Methamphetamine results in increased expression of MPRIP mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:17,042,457...17,192,643
Ensembl chr17:17,042,457...17,217,679
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G |
MRM3 |
mitochondrial rRNA methyltransferase 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of MRM3 mRNA |
CTD |
PMID:36914120 |
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NCBI chr17:782,353...792,509
Ensembl chr17:782,353...792,509
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G |
MRPL12 |
mitochondrial ribosomal protein L12 |
increases expression |
ISO |
Methamphetamine results in increased expression of MRPL12 mRNA |
CTD |
PMID:19149911 |
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NCBI chr17:81,703,367...81,707,517
Ensembl chr17:81,703,367...81,707,517
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G |
MRPL18 |
mitochondrial ribosomal protein L18 |
multiple interactions |
ISO |
Lithium inhibits the reaction [Methamphetamine results in increased expression of MRPL18 mRNA] |
CTD |
PMID:19149911 |
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NCBI chr 6:159,789,812...159,798,429
Ensembl chr 6:159,789,812...159,798,436
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G |
MRPL32 |
mitochondrial ribosomal protein L32 |
increases expression |
ISO |
Methamphetamine results in increased expression of MRPL32 mRNA |
CTD |
PMID:19149911 |
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NCBI chr 7:42,932,376...42,937,857
Ensembl chr 7:42,932,376...42,948,958
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G |
MRPL41 |
mitochondrial ribosomal protein L41 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of MRPL41 mRNA Valproic Acid inhibits the reaction [Methamphetamine results in increased expression of MRPL41 mRNA] |
CTD |
PMID:19149911 |
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NCBI chr 9:137,551,879...137,552,555
Ensembl chr 9:137,551,879...137,552,555
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G |
MRPL43 |
mitochondrial ribosomal protein L43 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MRPL43 mRNA |
CTD |
PMID:19149911 |
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NCBI chr10:100,977,820...100,987,497
Ensembl chr10:100,969,458...100,987,515
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G |
MRPL53 |
mitochondrial ribosomal protein L53 |
multiple interactions increases expression |
ISO |
Lithium inhibits the reaction [Methamphetamine results in increased expression of MRPL53 mRNA] |
CTD |
PMID:19149911 |
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NCBI chr 2:74,471,982...74,472,680
Ensembl chr 2:74,471,982...74,472,687
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G |
MSTO1 |
misato mitochondrial distribution and morphology regulator 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of MSTO1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:155,563,246...155,614,967
Ensembl chr 1:155,563,235...155,614,951
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G |
MT-CO1 |
mitochondrially encoded cytochrome c oxidase I |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of COX1 mRNA (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in increased expression of COX1 mRNA] |
CTD |
PMID:11756511 |
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NCBI chr MT:5,904...7,445
Ensembl chr MT:5,904...7,445
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MT-ND2 |
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2 |
multiple interactions decreases expression |
ISO |
(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of ND2 mRNA] |
CTD |
PMID:11756511 |
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NCBI chr MT:4,470...5,511
Ensembl chr MT:4,470...5,511
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G |
MT2A |
metallothionein 2A |
increases expression |
EXP ISO |
Methamphetamine results in increased expression of MT2A mRNA Methamphetamine results in increased expression of MT2 mRNA |
CTD |
PMID:20801194 PMID:36914120 |
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NCBI chr16:56,608,584...56,609,497
Ensembl chr16:56,608,584...56,609,497
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G |
MT3 |
metallothionein 3 |
decreases response to substance |
ISO |
MT3 protein results in decreased susceptibility to Methamphetamine |
CTD |
PMID:20801194 |
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NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088
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G |
MTA1 |
metastasis associated 1 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of MTA1 promoter |
CTD |
PMID:26307267 |
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NCBI chr14:105,419,827...105,470,729
Ensembl chr14:105,419,820...105,470,729
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G |
MTARC1 |
mitochondrial amidoxime reducing component 1 |
affects response to substance |
EXP |
MTARC1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 1:220,786,913...220,819,659
Ensembl chr 1:220,786,352...220,819,659
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G |
MTARC2 |
mitochondrial amidoxime reducing component 2 |
affects response to substance |
EXP |
MTARC2 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 1:220,748,322...220,784,815
Ensembl chr 1:220,748,225...220,784,815
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G |
MTHFD2 |
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
increases expression |
ISO |
Methamphetamine results in increased expression of MTHFD2 mRNA |
CTD |
PMID:28619521 |
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NCBI chr 2:74,198,615...74,217,565
Ensembl chr 2:74,186,172...74,217,565
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MTHFSD |
methenyltetrahydrofolate synthetase domain containing |
increases expression |
ISO |
Methamphetamine results in increased expression of MTHFSD mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:86,530,186...86,555,235
Ensembl chr16:86,530,178...86,555,235
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G |
MTNR1B |
melatonin receptor 1B |
multiple interactions |
EXP |
MTNR1B protein promotes the reaction [Melatonin inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]] |
CTD |
PMID:26283214 |
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NCBI chr11:92,969,651...92,984,960
Ensembl chr11:92,969,651...92,985,066
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G |
MTOR |
mechanistic target of rapamycin kinase |
multiple interactions increases phosphorylation decreases phosphorylation |
EXP ISO |
DDIT4 protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; Methamphetamine inhibits the reaction [MTOR protein results in increased phosphorylation of EIF4EBP1 protein] Methamphetamine results in increased phosphorylation of MTOR protein SNCA protein affects the reaction [Methamphetamine results in increased phosphorylation of MTOR protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased phosphorylation of MTOR protein] CEBPB protein affects the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; DDIT4 protein promotes the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein]; Methamphetamine results in increased expression of and results in increased phosphorylation of MTOR protein; Taurine inhibits the reaction [Methamphetamine results in decreased phosphorylation of MTOR protein] |
CTD |
PMID:19054297 PMID:23041169 PMID:26825372 PMID:31059759 PMID:34374793 PMID:34562559 PMID:35863504 More...
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NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556
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G |
MTPN |
myotrophin |
affects expression |
ISO |
Methamphetamine affects the expression of MTPN protein |
CTD |
PMID:17904249 |
|
NCBI chr 7:135,926,760...135,977,359
Ensembl chr 7:135,926,760...135,977,359
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G |
MUS81 |
MUS81 structure-specific endonuclease subunit |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of MUS81 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of MUS81 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:65,859,674...65,867,653
Ensembl chr11:65,857,126...65,867,653
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G |
MUTYH |
mutY DNA glycosylase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MUTYH mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:45,329,242...45,340,440
Ensembl chr 1:45,329,163...45,340,893
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G |
MVD |
mevalonate diphosphate decarboxylase |
increases methylation |
ISO |
Methamphetamine results in increased methylation of MVD promoter |
CTD |
PMID:26307267 |
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NCBI chr16:88,651,940...88,663,091
Ensembl chr16:88,651,935...88,663,161
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G |
MVK |
mevalonate kinase |
increases expression |
EXP |
Methamphetamine results in increased expression of MVK mRNA |
CTD |
PMID:25290377 |
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NCBI chr12:109,573,272...109,598,125
Ensembl chr12:109,573,255...109,598,125
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G |
MXD4 |
MAX dimerization protein 4 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MXD4 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 4:2,247,432...2,262,109
Ensembl chr 4:2,247,432...2,262,109
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G |
MYBPC3 |
myosin binding protein C3 |
increases expression |
ISO |
Methamphetamine results in increased expression of MYBPC3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:47,331,406...47,352,702
Ensembl chr11:47,331,406...47,352,702
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G |
MYC |
MYC proto-oncogene, bHLH transcription factor |
increases expression |
ISO |
Methamphetamine results in increased expression of MYC mRNA |
CTD |
PMID:19564919 |
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NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951
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MYD88 |
MYD88 innate immune signal transduction adaptor |
multiple interactions increases expression |
ISO |
Lactulose inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein] [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of MYD88 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MYD88 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein] Methamphetamine results in increased expression of MYD88 mRNA; Methamphetamine results in increased expression of MYD88 protein |
CTD |
PMID:30450033 PMID:33359793 PMID:35390362 PMID:35688268 PMID:36720452 |
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NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024
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MYH6 |
myosin heavy chain 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MYH6 mRNA Methamphetamine results in decreased expression of MYH6 protein |
CTD |
PMID:23933405 PMID:35863504 |
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NCBI chr14:23,381,987...23,408,273
Ensembl chr14:23,381,982...23,408,273
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G |
MYH7 |
myosin heavy chain 7 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MYH7 mRNA Methamphetamine results in decreased expression of MYH7 protein |
CTD |
PMID:23933405 PMID:35863504 |
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NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660
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G |
MYLK |
myosin light chain kinase |
affects expression multiple interactions increases expression |
ISO |
Methamphetamine affects the expression of MYLK mRNA [Methamphetamine co-treated with SCH 23390] affects the expression of MYLK mRNA Methamphetamine results in increased expression of MYLK mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr 3:123,610,049...123,884,332
Ensembl chr 3:123,610,049...123,884,332
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G |
MYO18A |
myosin XVIIIA |
increases expression |
ISO |
Methamphetamine results in increased expression of MYO18A mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:29,071,122...29,180,398
Ensembl chr17:29,071,122...29,180,398
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G |
MYO18B |
myosin XVIIIB |
increases expression |
ISO |
Methamphetamine results in increased expression of MYO18B mRNA |
CTD |
PMID:26307267 |
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NCBI chr22:25,742,188...26,063,847
Ensembl chr22:25,742,144...26,031,045
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G |
MYO5B |
myosin VB |
affects response to substance |
EXP |
MYO5B gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr18:49,822,789...50,195,147
Ensembl chr18:49,822,789...50,195,164
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G |
MYO7A |
myosin VIIA |
increases expression |
ISO |
Methamphetamine results in increased expression of MYO7A mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:77,128,246...77,215,241
Ensembl chr11:77,128,246...77,215,241
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G |
MYOM1 |
myomesin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of MYOM1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr18:3,066,807...3,247,376
Ensembl chr18:3,066,807...3,219,968
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G |
MYOM2 |
myomesin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of MYOM2 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 8:2,045,046...2,145,456
Ensembl chr 8:2,045,046...2,165,552
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G |
MYOT |
myotilin |
increases expression |
ISO |
Methamphetamine results in increased expression of MYOT mRNA |
CTD |
PMID:36914120 |
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NCBI chr 5:137,867,860...137,887,851
Ensembl chr 5:137,867,858...137,887,851
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G |
MYPN |
myopalladin |
increases expression |
ISO |
Methamphetamine results in increased expression of MYPN mRNA |
CTD |
PMID:36914120 |
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NCBI chr10:68,087,897...68,212,017
Ensembl chr10:68,087,897...68,212,017
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G |
MYT1 |
myelin transcription factor 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of MYT1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:64,164,452...64,242,253
Ensembl chr20:64,102,394...64,242,253
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G |
N4BP1 |
NEDD4 binding protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of N4BP1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:48,538,726...48,610,180
Ensembl chr16:48,538,726...48,620,148
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G |
NAB2 |
NGFI-A binding protein 2 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of NAB2 mRNA Methamphetamine results in increased expression of NAB2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:57,089,114...57,095,476
Ensembl chr12:57,089,043...57,095,476
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G |
NAMPT |
nicotinamide phosphoribosyltransferase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of NAMPT mRNA |
CTD |
PMID:35863504 |
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NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966
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G |
NCALD |
neurocalcin delta |
affects expression |
ISO |
Methamphetamine affects the expression of NCALD protein |
CTD |
PMID:17904249 |
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NCBI chr 8:101,686,542...102,124,907
Ensembl chr 8:101,686,542...102,124,907
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G |
NCAPG |
non-SMC condensin I complex subunit G |
decreases expression |
ISO |
Methamphetamine results in decreased expression of NCAPG mRNA |
CTD |
PMID:28341135 |
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NCBI chr 4:17,810,979...17,844,865
Ensembl chr 4:17,810,979...17,844,865
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G |
NCBP2AS2 |
NCBP2 antisense 2 (head to head) |
increases expression |
ISO |
Methamphetamine results in increased expression of NCBP2AS2 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 3:196,942,674...196,943,543
Ensembl chr 3:196,942,674...196,943,543
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G |
NCF1 |
neutrophil cytosolic factor 1 |
increases phosphorylation multiple interactions |
ISO |
Methamphetamine results in increased phosphorylation of NCF1 protein CCK protein modified form inhibits the reaction [Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein]]; CCK protein modified form inhibits the reaction [Methamphetamine results in increased phosphorylation of NCF1 protein]; Methamphetamine promotes the reaction [NCF1 protein binds to CYBB protein] |
CTD |
PMID:27565679 |
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NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315
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G |
NCOR2 |
nuclear receptor corepressor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of NCOR2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:124,324,415...124,567,612
Ensembl chr12:124,324,415...124,567,612
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G |
NDC80 |
NDC80 kinetochore complex component |
decreases expression |
ISO |
Methamphetamine results in decreased expression of NDC80 mRNA |
CTD |
PMID:28341135 |
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NCBI chr18:2,571,557...2,616,635
Ensembl chr18:2,571,557...2,616,635
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G |
NDRG3 |
NDRG family member 3 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of NDRG3 mRNA (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of NDRG3 mRNA] |
CTD |
PMID:11756511 |
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NCBI chr20:36,651,771...36,746,090
Ensembl chr20:36,651,766...36,746,090
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G |
NDST2 |
N-deacetylase and N-sulfotransferase 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of NDST2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:73,801,916...73,811,820
Ensembl chr10:73,801,911...73,811,798
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G |
NDST3 |
N-deacetylase and N-sulfotransferase 3 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of NDST3 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of NDST3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:118,033,322...118,258,634
Ensembl chr 4:118,033,618...118,258,634
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G |
NDUFA5 |
NADH:ubiquinone oxidoreductase subunit A5 |
increases expression |
ISO |
Methamphetamine results in increased expression of NDUFA5 mRNA |
CTD |
PMID:19149911 |
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NCBI chr 7:123,536,997...123,601,651
Ensembl chr 7:123,536,997...123,557,904
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G |
NDUFB6 |
NADH:ubiquinone oxidoreductase subunit B6 |
increases expression |
ISO |
Methamphetamine results in increased expression of NDUFB6 mRNA |
CTD |
PMID:19149911 |
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NCBI chr 9:32,553,001...32,573,159
Ensembl chr 9:32,553,001...32,573,184
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G |
NDUFS8 |
NADH:ubiquinone oxidoreductase core subunit S8 |
affects expression |
ISO |
Methamphetamine affects the expression of NDUFS8 protein |
CTD |
PMID:17904249 |
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NCBI chr11:68,030,681...68,036,644
Ensembl chr11:68,030,617...68,036,644
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G |
NDUFV2 |
NADH:ubiquinone oxidoreductase core subunit V2 |
increases expression |
ISO |
Methamphetamine results in increased expression of NDUFV2 protein |
CTD |
PMID:19826936 |
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NCBI chr18:9,102,699...9,134,341
Ensembl chr18:9,102,630...9,134,345
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G |
NECAB1 |
N-terminal EF-hand calcium binding protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of NECAB1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 8:90,791,775...90,959,393
Ensembl chr 8:90,791,741...90,959,393
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G |
NEFM |
neurofilament medium chain |
increases expression |
ISO |
Methamphetamine results in increased expression of NEFM mRNA |
CTD |
PMID:32035215 |
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NCBI chr 8:24,913,761...24,919,093
Ensembl chr 8:24,913,758...24,919,098
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G |
NEK10 |
NIMA related kinase 10 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of NEK10 mRNA |
CTD |
PMID:32035215 |
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NCBI chr 3:27,106,484...27,369,383
Ensembl chr 3:27,106,484...27,369,460
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G |
NEU4 |
neuraminidase 4 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of NEU4 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:241,809,193...241,817,413
Ensembl chr 2:241,809,065...241,817,413
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G |
NEURL2 |
neuralized E3 ubiquitin protein ligase 2 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of NEURL2 mRNA Methamphetamine results in decreased expression of NEURL2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:45,888,634...45,891,208
Ensembl chr20:45,888,625...45,891,208
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G |
NFAT5 |
nuclear factor of activated T cells 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of NFAT5 mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:69,565,966...69,704,654
Ensembl chr16:69,565,094...69,704,666
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G |
NFATC3 |
nuclear factor of activated T cells 3 |
affects localization increases expression multiple interactions |
ISO |
Methamphetamine affects the localization of NFATC3 protein Methamphetamine results in increased expression of NFATC3 mRNA SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFATC3 protein] |
CTD |
PMID:15644446 PMID:19564919 |
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NCBI chr16:68,085,370...68,229,259
Ensembl chr16:68,084,751...68,229,259
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G |
NFATC4 |
nuclear factor of activated T cells 4 |
affects localization decreases expression multiple interactions |
ISO |
Methamphetamine affects the localization of NFATC4 protein Methamphetamine results in decreased expression of NFATC4 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of NFATC4 mRNA; SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFATC4 protein] |
CTD |
PMID:15644446 PMID:19564919 |
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NCBI chr14:24,366,911...24,379,604
Ensembl chr14:24,365,673...24,379,604
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G |
NFE2L2 |
NFE2 like bZIP transcription factor 2 |
increases expression affects response to substance multiple interactions affects localization |
ISO |
Methamphetamine results in increased expression of NFE2L2 mRNA NFE2L2 protein affects the susceptibility to Methamphetamine NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of BECN1 protein]; NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of HAVCR1 protein]; NFE2L2 protein affects the reaction [Methamphetamine results in increased expression of MAP1LC3B protein]; sulforaphane promotes the reaction [Methamphetamine results in increased expression of NFE2L2 protein] Lactulose promotes the reaction [Methamphetamine results in increased expression of NFE2L2 mRNA]; SCH 23390 inhibits the reaction [Methamphetamine affects the localization of NFE2L2 protein]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of NFE2L2 mRNA] |
CTD |
PMID:19564919 PMID:30450033 PMID:37567421 |
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NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756
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G |
NFIL3 |
nuclear factor, interleukin 3 regulated |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of NFIL3 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of NFIL3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:91,409,045...91,483,497
Ensembl chr 9:91,409,045...91,423,832
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G |
NFKB1 |
nuclear factor kappa B subunit 1 |
increases activity affects localization multiple interactions increases expression |
EXP ISO |
Methamphetamine results in increased activity of NFKB1 protein Methamphetamine affects the localization of NFKB1 protein [SNCA protein co-treated with Methamphetamine] results in increased expression of NFKB1 protein; Methamphetamine promotes the reaction [NFKB1 protein binds to MIR143 promoter]; NFKB1 protein affects the reaction [Methamphetamine results in decreased expression of MIR143 mRNA] Methamphetamine results in increased expression of NFKB1 mRNA; Methamphetamine results in increased expression of NFKB1 protein |
CTD |
PMID:11746378 PMID:26307267 PMID:30394308 PMID:32569805 |
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NCBI chr 4:102,501,359...102,617,302
Ensembl chr 4:102,501,330...102,617,302
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G |
NFKBIA |
NFKB inhibitor alpha |
increases expression decreases expression multiple interactions increases phosphorylation increases degradation |
ISO EXP |
Methamphetamine results in increased expression of NFKBIA mRNA Methamphetamine results in decreased expression of NFKBIA mRNA CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]] Methamphetamine results in increased degradation of NFKBIA protein ERN1 protein affects the reaction [Methamphetamine results in increased phosphorylation of NFKBIA protein]; luzindole inhibits the reaction [Melatonin inhibits the reaction [Methamphetamine results in increased degradation of NFKBIA protein]]; Melatonin inhibits the reaction [Methamphetamine results in increased degradation of NFKBIA protein] |
CTD |
PMID:26283214 PMID:26307267 PMID:27323860 PMID:32916201 PMID:36914120 |
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NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749
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G |
NGF |
nerve growth factor |
decreases response to substance multiple interactions |
ISO |
NGF protein results in decreased susceptibility to Methamphetamine [Methamphetamine co-treated with NGF protein] affects the abundance of Peroxynitrous Acid |
CTD |
PMID:12105096 PMID:15093677 |
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NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770
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G |
NHERF1 |
NHERF family PDZ scaffold protein 1 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of NHERF1 mRNA (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of NHERF1 mRNA] |
CTD |
PMID:11756511 PMID:26307267 |
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NCBI chr17:74,748,628...74,769,353
Ensembl chr17:74,748,628...74,769,353
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G |
NHERF2 |
NHERF family PDZ scaffold protein 2 |
decreases expression increases expression |
ISO |
Methamphetamine results in decreased expression of NHERF2 mRNA Methamphetamine results in increased expression of NHERF2 mRNA |
CTD |
PMID:19564919 PMID:32035215 |
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NCBI chr16:2,026,902...2,039,026
Ensembl chr16:2,025,356...2,039,026
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G |
NHLRC2 |
NHL repeat containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of NHLRC2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:113,854,661...113,917,194
Ensembl chr10:113,854,661...113,917,194
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G |
NIPAL1 |
NIPA like domain containing 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of NIPAL1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 4:48,016,772...48,040,173
Ensembl chr 4:47,914,142...48,040,173
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G |
NKX2-5 |
NK2 homeobox 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of NKX2-5 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 5:173,232,109...173,235,206
Ensembl chr 5:173,232,109...173,235,311
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G |
NKX2-6 |
NK2 homeobox 6 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] affects the expression of NKX2-6 mRNA Methamphetamine results in decreased expression of NKX2-6 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 8:23,701,740...23,706,756
Ensembl chr 8:23,701,740...23,706,756
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G |
NKX6-2 |
NK6 homeobox 2 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of NKX6-2 mRNA Methamphetamine results in decreased expression of NKX6-2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:132,783,181...132,786,147
Ensembl chr10:132,783,179...132,786,147
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G |
NLRP3 |
NLR family pyrin domain containing 3 |
multiple interactions increases expression |
ISO |
Methamphetamine promotes the reaction [PYCARD protein binds to NLRP3 protein]; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of NLRP3 protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased expression of NLRP3 protein] |
CTD |
PMID:30394308 |
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NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108
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G |
NMU |
neuromedin U |
increases expression |
ISO |
Methamphetamine results in increased expression of NMU mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:55,595,231...55,636,793
Ensembl chr 4:55,595,229...55,636,698
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G |
NNT |
nicotinamide nucleotide transhydrogenase |
increases expression |
ISO |
Methamphetamine results in increased expression of NNT mRNA |
CTD |
PMID:19149911 PMID:36914120 |
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NCBI chr 5:43,602,675...43,707,396
Ensembl chr 5:43,602,692...43,707,405
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G |
NOCT |
nocturnin |
increases expression |
ISO |
Methamphetamine results in increased expression of NOCT mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:139,015,781...139,045,939
Ensembl chr 4:139,015,781...139,045,939
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G |
NOS1 |
nitric oxide synthase 1 |
multiple interactions affects response to substance increases expression |
ISO |
[3-bromo-7-nitroindazole results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine; [7-nitroindazole results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine; [7-nitroindazole results in decreased activity of NOS1 protein] which results in decreased susceptibility to Methamphetamine; [S-methylthiocitrulline results in decreased activity of NOS1 protein] which affects the susceptibility to Methamphetamine; NOS1 protein affects the reaction [Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein]]; NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of 3,4-Dihydroxyphenylacetic Acid]; NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of Dopamine]; NOS1 protein affects the reaction [Methamphetamine results in decreased abundance of Homovanillic Acid]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; NOS1 protein affects the reaction [Methamphetamine results in increased expression of TRP53 protein] NOS1 protein affects the susceptibility to Methamphetamine Methamphetamine results in increased expression of NOS1 protein |
CTD |
PMID:8858965 PMID:9495865 PMID:10642852 PMID:11006970 PMID:11085313 PMID:11158245 PMID:11457507 PMID:12050851 PMID:15542708 PMID:17426488 PMID:20575850 More...
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NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170
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G |
NOS2 |
nitric oxide synthase 2 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of NOS2 protein BBC3 protein promotes the reaction [Methamphetamine results in increased expression of NOS2 protein]; isoliquiritigenin inhibits the reaction [Methamphetamine results in increased expression of NOS2 protein]; MIR143 mRNA affects the reaction [Methamphetamine results in increased expression of NOS2 protein] |
CTD |
PMID:19834288 PMID:30394308 |
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NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529
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G |
NOTUM |
notum, palmitoleoyl-protein carboxylesterase |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of NOTUM mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of NOTUM mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:81,952,507...81,961,187
Ensembl chr17:81,952,507...81,961,840
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G |
NPAS2 |
neuronal PAS domain protein 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of NPAS2 mRNA |
CTD |
PMID:35863504 |
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NCBI chr 2:100,818,723...100,996,829
Ensembl chr 2:100,820,139...100,996,829
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G |
NPAS4 |
neuronal PAS domain protein 4 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of NPAS4 mRNA Methamphetamine results in increased expression of NPAS4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:66,409,158...66,426,707
Ensembl chr11:66,421,035...66,426,707
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G |
NPPB |
natriuretic peptide B |
increases expression |
ISO |
Methamphetamine results in increased expression of NPPB protein; Methamphetamine results in increased expression of NPPB protein modified form |
CTD |
PMID:35863504 |
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NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945
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G |
NPTX2 |
neuronal pentraxin 2 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of NPTX2 mRNA Methamphetamine results in increased expression of NPTX2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 7:98,617,285...98,629,869
Ensembl chr 7:98,617,285...98,629,869
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G |
NPY |
neuropeptide Y |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of NPY mRNA Methamphetamine results in decreased expression of NPY protein |
CTD |
PMID:15930374 PMID:17910739 |
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NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862
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G |
NPY1R |
neuropeptide Y receptor Y1 |
increases response to substance affects expression |
EXP ISO |
NPY1R gene SNP results in increased susceptibility to Methamphetamine Methamphetamine affects the expression of NPY1R mRNA |
CTD |
PMID:15930374 PMID:19566775 |
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NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832
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G |
NPY2R |
neuropeptide Y receptor Y2 |
affects expression increases expression |
ISO EXP |
Methamphetamine affects the expression of NPY2R mRNA Methamphetamine results in increased expression of NPY2R protein |
CTD |
PMID:15930374 PMID:32956829 |
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NCBI chr 4:155,173,723...155,217,076
Ensembl chr 4:155,208,636...155,217,078
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G |
NQO1 |
NAD(P)H quinone dehydrogenase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of NQO1 protein |
CTD |
PMID:16403784 |
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NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668
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G |
NR1D1 |
nuclear receptor subfamily 1 group D member 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of NR1D1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr17:40,092,793...40,100,589
Ensembl chr17:40,092,793...40,100,589
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G |
NR1H4 |
nuclear receptor subfamily 1 group H member 4 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of NR1H4 mRNA; Methamphetamine results in increased expression of NR1H4 protein obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of NR1H4 mRNA]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of NR1H4 protein] |
CTD |
PMID:35688268 |
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NCBI chr12:100,473,866...100,564,414
Ensembl chr12:100,473,708...100,564,414
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G |
NR3C1 |
nuclear receptor subfamily 3 group C member 1 |
multiple interactions affects expression |
ISO |
[RU 43044 binds to and results in decreased activity of NR3C1 protein] inhibits the reaction [Methamphetamine results in increased secretion of Dopamine]; [RU 43044 binds to and results in decreased activity of NR3C1 protein] which results in decreased susceptibility to Methamphetamine Methamphetamine affects the expression of NR3C1 mRNA |
CTD |
PMID:17254711 PMID:18925659 |
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NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512
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G |
NR4A1 |
nuclear receptor subfamily 4 group A member 1 |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of NR4A1 mRNA Methamphetamine results in decreased expression of NR4A1 mRNA |
CTD |
PMID:15644446 PMID:32035215 |
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NCBI chr12:52,022,832...52,059,503
Ensembl chr12:52,022,832...52,059,507
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G |
NR4A2 |
nuclear receptor subfamily 4 group A member 2 |
multiple interactions decreases expression increases expression affects response to substance |
ISO |
[SNCA protein co-treated with Methamphetamine] results in decreased expression of NR4A2 protein; NR4A2 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; NR4A2 protein affects the reaction [Methamphetamine results in decreased expression of TH protein] Methamphetamine results in decreased expression of NR4A2 protein [Methamphetamine co-treated with SCH 23390] results in increased expression of NR4A2 mRNA Methamphetamine results in increased expression of NR4A2 mRNA NR4A2 protein affects the susceptibility to Methamphetamine |
CTD |
PMID:19564919 PMID:21151937 PMID:32569805 |
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NCBI chr 2:156,324,437...156,332,721
Ensembl chr 2:156,324,437...156,342,348
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G |
NR4A3 |
nuclear receptor subfamily 4 group A member 3 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of NR4A3 mRNA Methamphetamine results in increased expression of NR4A3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:99,821,885...99,866,891
Ensembl chr 9:99,821,855...99,866,891
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G |
NRADDP |
neurotrophin receptor associated death domain, pseudogene |
increases expression |
ISO |
Methamphetamine results in increased expression of NRADD mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:47,011,542...47,013,467
Ensembl chr 3:47,011,542...47,013,146
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G |
NRBP2 |
nuclear receptor binding protein 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of NRBP2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 8:143,829,776...143,840,973
Ensembl chr 8:143,833,583...143,840,973
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G |
NRF1 |
nuclear respiratory factor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of NRF1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:129,611,720...129,757,076
Ensembl chr 7:129,611,720...129,757,082
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G |
NRG1 |
neuregulin 1 |
affects response to substance |
EXP |
NRG1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 8:31,639,245...32,774,046
Ensembl chr 8:31,639,222...32,855,666
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G |
NRM |
nurim |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of NRM mRNA Methamphetamine results in decreased expression of NRM mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:30,688,049...30,691,420
Ensembl chr 6:30,688,047...30,691,420
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G |
NSMAF |
neutral sphingomyelinase activation associated factor |
increases expression |
ISO |
Methamphetamine results in increased expression of NSMAF mRNA |
CTD |
PMID:26307267 |
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NCBI chr 8:58,583,504...58,659,853
Ensembl chr 8:58,583,508...58,659,853
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G |
NSMF |
NMDA receptor synaptonuclear signaling and neuronal migration factor |
increases expression |
ISO |
Methamphetamine results in increased expression of NSMF mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:137,447,570...137,459,334
Ensembl chr 9:137,447,570...137,459,334
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G |
NTHL1 |
nth like DNA glycosylase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of NTHL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:2,039,820...2,047,834
Ensembl chr16:2,039,815...2,047,866
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G |
NTRK2 |
neurotrophic receptor tyrosine kinase 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of NTRK2 protein |
CTD |
PMID:34461196 |
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NCBI chr 9:84,668,522...85,027,054
Ensembl chr 9:84,668,375...85,095,751
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G |
NTS |
neurotensin |
increases expression |
ISO |
Methamphetamine results in increased expression of NTS mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:85,874,295...85,882,992
Ensembl chr12:85,874,295...85,882,992
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G |
NUF2 |
NUF2 component of NDC80 kinetochore complex |
decreases expression |
ISO |
Methamphetamine results in decreased expression of NUF2 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 1:163,321,954...163,355,759
Ensembl chr 1:163,266,576...163,355,764
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G |
NUP210L |
nucleoporin 210 like |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of NUP210L mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of NUP210L mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:153,992,690...154,155,116
Ensembl chr 1:153,992,690...154,155,116
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G |
NXPH3 |
neurexophilin 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of NXPH3 mRNA |
CTD |
PMID:15644446 |
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NCBI chr17:49,575,871...49,583,827
Ensembl chr17:49,575,871...49,583,827
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G |
OAS2 |
2'-5'-oligoadenylate synthetase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of OAS2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:112,978,519...113,011,723
Ensembl chr12:112,978,395...113,011,723
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G |
OBSCN |
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF |
increases expression |
ISO |
Methamphetamine results in increased expression of OBSCN mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:228,208,044...228,378,876
Ensembl chr 1:228,208,044...228,378,876
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G |
OBSL1 |
obscurin like cytoskeletal adaptor 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of OBSL1 mRNA Methamphetamine results in decreased expression of OBSL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:219,547,206...219,571,539
Ensembl chr 2:219,550,728...219,571,859
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G |
OCLN |
occludin |
multiple interactions decreases expression |
ISO |
[Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of OCLN mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of OCLN protein]; obeticholic acid inhibits the reaction [Methamphetamine results in decreased expression of OCLN protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of OCLN protein] Methamphetamine results in decreased expression of OCLN mRNA; Methamphetamine results in decreased expression of OCLN protein |
CTD |
PMID:35390362 PMID:36720452 |
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NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104
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G |
OGDHL |
oxoglutarate dehydrogenase L |
increases expression |
EXP ISO |
Methamphetamine results in increased expression of OGDHL mRNA |
CTD |
PMID:25290377 PMID:36914120 |
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NCBI chr10:49,734,641...49,762,379
Ensembl chr10:49,734,641...49,762,379
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G |
OGG1 |
8-oxoguanine DNA glycosylase |
multiple interactions decreases expression affects response to substance |
ISO |
OGG1 protein affects the reaction [Methamphetamine results in increased abundance of 7,8-dihydro-8-oxoguanine] Methamphetamine results in decreased expression of OGG1 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of OGG1 mRNA OGG1 protein affects the susceptibility to Methamphetamine |
CTD |
PMID:18768699 PMID:19564919 |
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NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219
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G |
OMA1 |
OMA1 zinc metallopeptidase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of OMA1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:58,480,719...58,546,726
Ensembl chr 1:58,415,384...58,546,802
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G |
ONECUT1 |
one cut homeobox 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ONECUT1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr15:52,755,053...52,790,336
Ensembl chr15:52,755,053...52,791,078
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G |
OPRL1 |
opioid related nociceptin receptor 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of OPRL1 mRNA |
CTD |
PMID:21886566 |
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NCBI chr20:64,080,082...64,100,643
Ensembl chr20:64,080,082...64,100,643
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G |
OPRM1 |
opioid receptor mu 1 |
increases response to substance decreases expression multiple interactions increases expression |
EXP ISO |
OPRM1 gene SNP results in increased susceptibility to Methamphetamine Methamphetamine results in decreased expression of OPRM1 mRNA; Methamphetamine results in decreased expression of OPRM1 protein Fluoxetine inhibits the reaction [Methamphetamine results in decreased expression of OPRM1 mRNA]; Fluoxetine inhibits the reaction [Methamphetamine results in decreased expression of OPRM1 protein]; OPRM1 protein affects the susceptibility to [Methamphetamine results in decreased expression of TH mRNA]; OPRM1 protein affects the susceptibility to [Methamphetamine results in decreased expression of TH protein]; OPRM1 protein inhibits the reaction [Haloperidol inhibits the reaction [Methamphetamine results in increased expression of EGR1 mRNA]] Methamphetamine results in increased expression of OPRM1 mRNA [CTAP octapeptide binds to and results in decreased activity of OPRM1 protein] which results in decreased susceptibility to Methamphetamine |
CTD |
PMID:15644446 PMID:16402083 PMID:20184921 PMID:20298714 PMID:21886566 PMID:22329540 More...
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NCBI chr 6:154,010,496...154,246,867
Ensembl chr 6:154,010,496...154,246,867
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G |
OR51E2 |
olfactory receptor family 51 subfamily E member 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of OLR59 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:4,680,171...4,697,853
Ensembl chr11:4,680,171...4,697,854
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G |
ORC1 |
origin recognition complex subunit 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of ORC1 mRNA |
CTD |
PMID:25290377 |
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NCBI chr 1:52,372,829...52,409,503
Ensembl chr 1:52,372,829...52,404,423
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G |
OSGIN1 |
oxidative stress induced growth inhibitor 1 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of OSGIN1 promoter |
CTD |
PMID:26307267 |
|
NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,332
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G |
OVCH2 |
ovochymase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of OVCH2 mRNA |
CTD |
PMID:28341135 |
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NCBI chr11:7,678,693...7,706,477
Ensembl chr11:7,689,437...7,706,477
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G |
OXGR1 |
oxoglutarate receptor 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of OXGR1 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of OXGR1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr13:96,985,713...96,994,730
Ensembl chr13:96,985,713...96,994,730
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G |
OXT |
oxytocin/neurophysin I prepropeptide |
multiple interactions affects expression |
ISO |
[Methamphetamine co-treated with SCH 23390] affects the expression of OXT mRNA Methamphetamine affects the expression of OXT mRNA |
CTD |
PMID:19564919 |
|
NCBI chr20:3,071,620...3,072,517
Ensembl chr20:3,071,620...3,072,517
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G |
P2RX4 |
purinergic receptor P2X 4 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of P2RX4 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr12:121,210,129...121,234,106
Ensembl chr12:121,210,065...121,234,106
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G |
P2RX6 |
purinergic receptor P2X 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of P2RX6 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr22:21,009,799...21,028,008
Ensembl chr22:21,009,808...21,028,013
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G |
P2RY2 |
purinergic receptor P2Y2 |
increases expression |
ISO |
Methamphetamine results in increased expression of P2RY2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:73,218,281...73,242,427
Ensembl chr11:73,218,281...73,242,427
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G |
P4HA1 |
prolyl 4-hydroxylase subunit alpha 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of P4HA1 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of P4HA1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:73,007,217...73,096,866
Ensembl chr10:73,007,217...73,096,974
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G |
P4HA2 |
prolyl 4-hydroxylase subunit alpha 2 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of P4HA2 mRNA Methamphetamine results in increased expression of P4HA2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:132,190,147...132,227,853
Ensembl chr 5:132,190,147...132,295,315
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G |
PACSIN1 |
protein kinase C and casein kinase substrate in neurons 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PACSIN1 protein |
CTD |
PMID:19826936 |
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NCBI chr 6:34,466,076...34,535,223
Ensembl chr 6:34,466,061...34,535,229
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G |
PADI6 |
peptidyl arginine deiminase 6 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PADI6 mRNA Methamphetamine results in decreased expression of PADI6 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:17,372,196...17,401,699
Ensembl chr 1:17,372,196...17,401,699
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G |
PAIP1 |
poly(A) binding protein interacting protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PAIP1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 5:43,526,267...43,557,411
Ensembl chr 5:43,526,267...43,557,758
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G |
PAK6 |
p21 (RAC1) activated kinase 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PAK6 mRNA |
CTD |
PMID:35863504 |
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NCBI chr15:40,239,063...40,277,487
Ensembl chr15:40,217,428...40,277,487
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G |
PALLD |
palladin, cytoskeletal associated protein |
increases expression |
ISO |
Methamphetamine results in increased expression of PALLD mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 4:168,497,052...168,928,441
Ensembl chr 4:168,497,052...168,928,457
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G |
PARD3 |
par-3 family cell polarity regulator |
increases expression |
ISO |
Methamphetamine results in increased expression of PARD3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:34,109,561...34,815,296
Ensembl chr10:34,109,560...34,815,325
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G |
PARD6G |
par-6 family cell polarity regulator gamma |
affects expression multiple interactions |
ISO |
Methamphetamine affects the expression of PARD6G mRNA [Methamphetamine co-treated with SCH 23390] affects the expression of PARD6G mRNA |
CTD |
PMID:19564919 |
|
NCBI chr18:80,157,232...80,247,514
Ensembl chr18:80,157,232...80,247,514
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G |
PARP1 |
poly(ADP-ribose) polymerase 1 |
increases activity increases cleavage increases expression decreases cleavage multiple interactions |
ISO EXP |
Methamphetamine results in increased activity of PARP1 protein Methamphetamine results in increased cleavage of PARP1 protein Methamphetamine results in increased expression of PARP1 protein modified form Methamphetamine results in decreased cleavage of PARP1 protein 3-methyladenine promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; CASP4 protein alternative form affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; CEBPB protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; Chloroquine promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; DDIT3 protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; DDIT4 protein promotes the reaction [Methamphetamine results in increased expression of PARP1 protein modified form]; IGFBP5 mutant form inhibits the reaction [Methamphetamine results in increased activity of PARP1 protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of PARP1 protein modified form]; Sirolimus inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; wedelolactone inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein] BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; SNCA protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein] |
CTD |
PMID:25127757 PMID:25523949 PMID:25631491 PMID:26524635 PMID:26825372 PMID:28341135 PMID:30450033 PMID:31059759 PMID:34214594 PMID:34374793 PMID:36914120 More...
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NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154
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G |
PARP8 |
poly(ADP-ribose) polymerase family member 8 |
increases expression |
ISO |
Methamphetamine results in increased expression of PARP8 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 5:50,665,931...50,846,519
Ensembl chr 5:50,665,899...50,846,519
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G |
PAWR |
pro-apoptotic WT1 regulator |
increases expression |
ISO |
Methamphetamine results in increased expression of PAWR mRNA |
CTD |
PMID:19564919 |
|
NCBI chr12:79,584,879...79,690,964
Ensembl chr12:79,574,979...79,690,964
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G |
PBK |
PDZ binding kinase |
decreases expression |
EXP ISO |
Methamphetamine results in decreased expression of PBK mRNA |
CTD |
PMID:25290377 PMID:28341135 |
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NCBI chr 8:27,809,624...27,837,817
Ensembl chr 8:27,809,624...27,838,082
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G |
PBXIP1 |
PBX homeobox interacting protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PBXIP1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:154,944,080...154,956,099
Ensembl chr 1:154,944,076...154,956,123
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G |
PCBP4 |
poly(rC) binding protein 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of PCBP4 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:51,957,454...51,967,466
Ensembl chr 3:51,957,454...51,974,016
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G |
PCDH1 |
protocadherin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PCDH1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 5:141,853,090...141,878,410
Ensembl chr 5:141,853,090...141,879,246
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G |
PCGF6 |
polycomb group ring finger 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PCGF6 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:103,302,796...103,351,140
Ensembl chr10:103,302,796...103,351,144
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G |
PCLAF |
PCNA clamp associated factor |
decreases expression multiple interactions |
EXP ISO |
Methamphetamine results in decreased expression of PCLAF mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of PCLAF mRNA |
CTD |
PMID:19564919 PMID:25290377 |
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NCBI chr15:64,364,304...64,387,687
Ensembl chr15:64,364,304...64,387,687
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G |
PCMT1 |
protein-L-isoaspartate (D-aspartate) O-methyltransferase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PCMT1 protein |
CTD |
PMID:19826936 |
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NCBI chr 6:149,749,695...149,811,421
Ensembl chr 6:149,749,444...149,811,420
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G |
PCNT |
pericentrin |
increases expression |
ISO |
Methamphetamine results in increased expression of PCNT mRNA |
CTD |
PMID:26307267 |
|
NCBI chr21:46,324,156...46,445,769
Ensembl chr21:46,324,124...46,445,769
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G |
PCNX3 |
pecanex 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of PCNX3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:65,615,776...65,637,439
Ensembl chr11:65,615,776...65,637,439
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G |
PCOLCE2 |
procollagen C-endopeptidase enhancer 2 |
affects response to substance |
EXP |
PCOLCE2 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 3:142,817,874...142,889,083
Ensembl chr 3:142,815,922...142,889,206
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G |
PCP4 |
Purkinje cell protein 4 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PCP4 mRNA |
CTD |
PMID:32035215 |
|
NCBI chr21:39,867,438...39,929,392
Ensembl chr21:39,867,438...39,929,397
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G |
PCSK1 |
proprotein convertase subtilisin/kexin type 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PCSK1 mRNA Methamphetamine results in increased expression of PCSK1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:96,390,333...96,433,248
Ensembl chr 5:96,390,333...96,434,143
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G |
PCYOX1L |
prenylcysteine oxidase 1 like |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PCYOX1L mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:149,358,046...149,369,653
Ensembl chr 5:149,358,037...149,369,653
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G |
PCYT2 |
phosphate cytidylyltransferase 2, ethanolamine |
affects methylation increases expression |
ISO |
Methamphetamine affects the methylation of PCYT2 promoter Methamphetamine results in increased expression of PCYT2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:81,900,958...81,911,399
Ensembl chr17:81,900,958...81,911,432
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G |
PDE1B |
phosphodiesterase 1B |
affects response to substance |
ISO |
PDE1B protein affects the susceptibility to Methamphetamine |
CTD |
PMID:12077213 |
|
NCBI chr12:54,549,601...54,579,239
Ensembl chr12:54,549,601...54,579,239
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G |
PDE2A |
phosphodiesterase 2A |
increases expression increases methylation |
ISO |
Methamphetamine results in increased expression of PDE2A mRNA Methamphetamine results in increased methylation of PDE2A promoter |
CTD |
PMID:26307267 |
|
NCBI chr11:72,576,141...72,674,422
Ensembl chr11:72,576,141...72,674,591
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G |
PDE4B |
phosphodiesterase 4B |
affects response to substance |
EXP |
PDE4B gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 1:65,792,510...66,374,579
Ensembl chr 1:65,792,514...66,374,579
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G |
PDE4D |
phosphodiesterase 4D |
affects response to substance |
EXP |
PDE4D gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 5:58,969,038...60,522,128
Ensembl chr 5:58,969,038...60,522,120
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G |
PDE4DIP |
phosphodiesterase 4D interacting protein |
increases expression |
ISO |
Methamphetamine results in increased expression of PDE4DIP mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:148,808,434...149,033,016
Ensembl chr 1:148,808,140...149,048,286
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G |
PDE6C |
phosphodiesterase 6C |
affects response to substance |
EXP |
PDE6C gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr10:93,612,537...93,666,010
Ensembl chr10:93,612,537...93,666,010
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G |
PDE8A |
phosphodiesterase 8A |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PDE8A mRNA Methamphetamine results in decreased expression of PDE8A mRNA |
CTD |
PMID:19564919 |
|
NCBI chr15:84,980,467...85,139,142
Ensembl chr15:84,980,440...85,139,145
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G |
PDGFB |
platelet derived growth factor subunit B |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of PDGFB mRNA Luteolin inhibits the reaction [Methamphetamine results in increased expression of PDGFB mRNA] |
CTD |
PMID:26307267 PMID:32035215 |
|
NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982
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G |
PDGFRA |
platelet derived growth factor receptor alpha |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PDGFRA mRNA |
CTD |
PMID:28619521 |
|
NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245
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G |
PDHA1 |
pyruvate dehydrogenase E1 subunit alpha 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PDHA1 protein |
CTD |
PMID:19826936 |
|
NCBI chr X:19,343,927...19,361,718
Ensembl chr X:19,343,893...19,361,718
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G |
PDHB |
pyruvate dehydrogenase E1 subunit beta |
increases expression |
ISO |
Methamphetamine results in increased expression of PDHB protein |
CTD |
PMID:19826936 |
|
NCBI chr 3:58,427,630...58,433,832
Ensembl chr 3:58,427,630...58,433,857
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G |
PDIA3 |
protein disulfide isomerase family A member 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PDIA3 protein |
CTD |
PMID:19826936 |
|
NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279
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G |
PDIA4 |
protein disulfide isomerase family A member 4 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of PDIA4 mRNA SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PDIA4 mRNA] |
CTD |
PMID:19564919 PMID:36914120 |
|
NCBI chr 7:149,003,051...149,028,505
Ensembl chr 7:149,003,062...149,028,662
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G |
PDK4 |
pyruvate dehydrogenase kinase 4 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of PDK4 mRNA Methamphetamine results in increased expression of PDK4 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
|
NCBI chr 7:95,583,499...95,596,516
Ensembl chr 7:95,583,499...95,596,516
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G |
PDLIM7 |
PDZ and LIM domain 7 |
increases expression |
ISO |
Methamphetamine results in increased expression of PDLIM7 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:177,483,394...177,497,604
Ensembl chr 5:177,483,394...177,497,606
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G |
PDP1 |
pyruvate dehydrogenase phosphatase catalytic subunit 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PDP1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:93,916,923...93,926,068
Ensembl chr 8:93,857,807...93,926,068
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G |
PDYN |
prodynorphin |
increases response to substance multiple interactions decreases expression increases expression |
EXP ISO |
PDYN promoter polymorphism results in increased susceptibility to Methamphetamine PDYN gene mutant form results in increased susceptibility to Methamphetamine 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [[PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]]; 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [PDYN gene mutant form results in increased susceptibility to Methamphetamine]; [PDYN gene mutant form results in increased susceptibility to Methamphetamine] which results in increased expression of GFAP protein; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of PDYN mRNA]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of AIF1 protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of BAX protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of TAC1 mRNA]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of TAC1 protein modified form] Methamphetamine results in decreased expression of PDYN mRNA; Methamphetamine results in decreased expression of PDYN protein Methamphetamine results in increased expression of PDYN mRNA CTAP octapeptide inhibits the reaction [Methamphetamine results in increased expression of PDYN mRNA] |
CTD |
PMID:16529859 PMID:20298714 PMID:29467000 |
|
NCBI chr20:1,978,756...1,994,285
Ensembl chr20:1,978,757...1,994,285
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G |
PEBP1 |
phosphatidylethanolamine binding protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PEBP1 protein |
CTD |
PMID:19826936 |
|
NCBI chr12:118,136,124...118,145,584
Ensembl chr12:118,136,124...118,145,584
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G |
PELI1 |
pellino E3 ubiquitin protein ligase 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of PELI1 protein PELI1 protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; PELI1 protein promotes the reaction [Methamphetamine results in increased expression of IL6 protein]; PELI1 protein promotes the reaction [Methamphetamine results in increased expression of TNF protein] |
CTD |
PMID:32768653 |
|
NCBI chr 2:64,092,652...64,144,420
Ensembl chr 2:64,092,652...64,144,420
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|
G |
PEMT |
phosphatidylethanolamine N-methyltransferase |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PEMT mRNA Methamphetamine results in decreased expression of PEMT mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:17,505,563...17,592,142
Ensembl chr17:17,505,563...17,591,708
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G |
PENK |
proenkephalin |
increases expression |
ISO |
Methamphetamine results in increased expression of PENK mRNA |
CTD |
PMID:19149911 |
|
NCBI chr 8:56,440,957...56,446,641
Ensembl chr 8:56,436,674...56,446,671
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G |
PER1 |
period circadian regulator 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PER1 mRNA |
CTD |
PMID:19564919 PMID:26307267 PMID:35863504 |
|
NCBI chr17:8,140,472...8,152,404
Ensembl chr17:8,140,472...8,156,506
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G |
PER2 |
period circadian regulator 2 |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of PER2 mRNA; Methamphetamine results in increased expression of PER2 protein Methamphetamine results in decreased expression of PER2 mRNA |
CTD |
PMID:15542705 PMID:15950759 PMID:19564919 PMID:35863504 |
|
NCBI chr 2:238,244,044...238,300,065
Ensembl chr 2:238,244,044...238,290,102
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G |
PER3 |
period circadian regulator 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of PER3 mRNA |
CTD |
PMID:35863504 |
|
NCBI chr 1:7,784,291...7,845,177
Ensembl chr 1:7,784,291...7,845,177
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G |
PEX6 |
peroxisomal biogenesis factor 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of PEX6 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 6:42,963,865...42,979,181
Ensembl chr 6:42,963,865...42,979,181
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G |
PFKFB2 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of PFKFB2 promoter Methamphetamine results in increased expression of PFKFB2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:207,034,416...207,081,027
Ensembl chr 1:207,034,366...207,081,024
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G |
PFKM |
phosphofructokinase, muscle |
increases expression |
ISO |
Methamphetamine results in increased expression of PFKM mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:48,105,353...48,146,404
Ensembl chr12:48,105,139...48,146,404
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G |
PFN2 |
profilin 2 |
affects expression |
ISO |
Methamphetamine affects the expression of PFN2 protein |
CTD |
PMID:17904249 |
|
NCBI chr 3:149,964,904...149,970,895
Ensembl chr 3:149,964,904...150,050,788
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G |
PGAM1 |
phosphoglycerate mutase 1 |
decreases expression increases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of PGAM1 mRNA Methamphetamine results in increased expression of PGAM1 mRNA (1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of PGAM1 mRNA] |
CTD |
PMID:11756511 PMID:36914120 |
|
NCBI chr10:97,426,191...97,433,444
Ensembl chr10:97,426,191...97,433,444
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G |
PGAP6 |
post-GPI attachment to proteins 6 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of PGAP6 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of PGAP6 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr16:370,788...386,979
Ensembl chr16:370,788...387,113
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G |
PGBD5 |
piggyBac transposable element derived 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of PGBD5 mRNA |
CTD |
PMID:28341135 |
|
NCBI chr 1:230,314,490...230,426,332
Ensembl chr 1:230,314,490...230,426,332
|
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G |
PGGHG |
protein-glucosylgalactosylhydroxylysine glucosidase |
increases expression |
ISO |
Methamphetamine results in increased expression of PGGHG mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:289,126...296,107
Ensembl chr11:289,126...296,107
|
|
G |
PGK1 |
phosphoglycerate kinase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PGK1 protein |
CTD |
PMID:19826936 |
|
NCBI chr X:78,104,248...78,129,295
Ensembl chr X:77,910,739...78,129,295
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G |
PGS1 |
phosphatidylglycerophosphate synthase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PGS1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:78,378,649...78,424,659
Ensembl chr17:78,378,649...78,425,114
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G |
PHB1 |
prohibitin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PHB1 protein |
CTD |
PMID:19826936 |
|
NCBI chr17:49,404,052...49,414,882
Ensembl chr17:49,404,049...49,414,905
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G |
PHF13 |
PHD finger protein 13 |
increases expression |
ISO |
Methamphetamine results in increased expression of PHF13 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:6,613,731...6,624,030
Ensembl chr 1:6,613,731...6,624,030
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G |
PHGDH |
phosphoglycerate dehydrogenase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PHGDH protein |
CTD |
PMID:19826936 |
|
NCBI chr 1:119,711,934...119,744,215
Ensembl chr 1:119,648,411...119,744,218
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G |
PHKG1 |
phosphorylase kinase catalytic subunit gamma 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PHKG1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:56,080,295...56,092,952
Ensembl chr 7:56,080,283...56,092,996
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G |
PHLDB1 |
pleckstrin homology like domain family B member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PHLDB1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:118,606,436...118,658,028
Ensembl chr11:118,606,440...118,658,031
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G |
PHLPP1 |
PH domain and leucine rich repeat protein phosphatase 1 |
affects expression increases expression |
ISO |
Methamphetamine affects the expression of PHLPP1 mRNA Methamphetamine results in increased expression of PHLPP1 protein |
CTD |
PMID:15542705 PMID:15950759 |
|
NCBI chr18:62,715,541...62,980,433
Ensembl chr18:62,715,541...62,980,433
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G |
PHRF1 |
PHD and ring finger domains 1 |
affects methylation increases expression |
ISO |
Methamphetamine affects the methylation of PHRF1 promoter Methamphetamine results in increased expression of PHRF1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:576,470...612,222
Ensembl chr11:576,470...612,222
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G |
PICK1 |
protein interacting with PRKCA 1 |
increases response to substance increases expression |
EXP ISO |
PICK1 gene SNP results in increased susceptibility to Methamphetamine Methamphetamine results in increased expression of PICK1 mRNA |
CTD |
PMID:17606663 PMID:26307267 |
|
NCBI chr22:38,057,255...38,075,701
Ensembl chr22:38,056,311...38,075,701
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G |
PIK3AP1 |
phosphoinositide-3-kinase adaptor protein 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PIK3AP1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:96,593,315...96,720,514
Ensembl chr10:96,593,315...96,720,514
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G |
PIK3IP1 |
phosphoinositide-3-kinase interacting protein 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PIK3IP1 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr22:31,281,593...31,292,534
Ensembl chr22:31,281,594...31,292,534
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|
G |
PIK3R1 |
phosphoinositide-3-kinase regulatory subunit 1 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of PIK3R1 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821
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G |
PIK3R5 |
phosphoinositide-3-kinase regulatory subunit 5 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of PIK3R5 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of PIK3R5 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:8,878,916...8,965,707
Ensembl chr17:8,878,911...8,965,712
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G |
PIK3R6 |
phosphoinositide-3-kinase regulatory subunit 6 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of PIK3R6 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of PIK3R6 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:8,802,722...8,867,677
Ensembl chr17:8,802,722...8,867,677
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G |
PILRA |
paired immunoglobin like type 2 receptor alpha |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PILRA mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:100,371,291...100,400,096
Ensembl chr 7:100,367,530...100,400,096
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|
G |
PIM3 |
Pim-3 proto-oncogene, serine/threonine kinase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PIM3 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr22:49,960,772...49,964,072
Ensembl chr22:49,960,768...49,964,072
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G |
PIMREG |
PICALM interacting mitotic regulator |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PIMREG mRNA |
CTD |
PMID:28341135 |
|
NCBI chr17:6,444,455...6,451,469
Ensembl chr17:6,444,441...6,451,469
|
|
G |
PIP5K1A |
phosphatidylinositol-4-phosphate 5-kinase type 1 alpha |
increases expression |
ISO |
Methamphetamine results in increased expression of PIP5K1A mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:151,195,419...151,249,531
Ensembl chr 1:151,197,949...151,249,536
|
|
G |
PITX3 |
paired like homeodomain 3 |
affects expression multiple interactions |
ISO |
Methamphetamine affects the expression of PITX3 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of PITX3 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr10:102,230,189...102,241,512
Ensembl chr10:102,230,189...102,241,512
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|
G |
PKDCC |
protein kinase domain containing, cytoplasmic |
increases expression |
ISO |
Methamphetamine results in increased expression of PKDCC mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 2:42,048,021...42,058,517
Ensembl chr 2:42,048,021...42,058,517
|
|
G |
PKM |
pyruvate kinase M1/2 |
increases expression |
ISO |
Methamphetamine results in increased expression of PKM protein |
CTD |
PMID:19826936 |
|
NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819
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|
G |
PKN3 |
protein kinase N3 |
increases expression |
ISO |
Methamphetamine results in increased expression of PKN3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 9:128,702,503...128,720,916
Ensembl chr 9:128,702,503...128,720,916
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G |
PKP2 |
plakophilin 2 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of PKP2 mRNA Methamphetamine results in increased expression of PKP2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:32,790,755...32,896,777
Ensembl chr12:32,790,745...32,896,798
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G |
PLA1A |
phospholipase A1 member A |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of PLA1A mRNA Methamphetamine results in increased expression of PLA1A mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:119,597,885...119,629,811
Ensembl chr 3:119,597,875...119,629,811
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PLA2G5 |
phospholipase A2 group V |
increases expression |
EXP |
Methamphetamine results in increased expression of PLA2G5 mRNA |
CTD |
PMID:25290377 |
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NCBI chr 1:20,028,408...20,091,911
Ensembl chr 1:20,028,179...20,091,911
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G |
PLAGL1 |
PLAG1 like zinc finger 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of PLAGL1 mRNA Methamphetamine results in increased expression of PLAGL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:143,940,300...144,064,599
Ensembl chr 6:143,940,300...144,064,599
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G |
PLAT |
plasminogen activator, tissue type |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of PLAT mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of PLAT mRNA Raclopride inhibits the reaction [Methamphetamine results in increased expression of PLAT mRNA]; SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PLAT mRNA] |
CTD |
PMID:15659235 PMID:19564919 |
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NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709
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G |
PLCB1 |
phospholipase C beta 1 |
multiple interactions increases expression |
ISO EXP |
candesartan cilexetil inhibits the reaction [Methamphetamine results in increased expression of PLCB1 protein] 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of PLCB1 mRNA] Methamphetamine results in increased expression of PLCB1 mRNA; Methamphetamine results in increased expression of PLCB1 protein |
CTD |
PMID:33421459 |
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NCBI chr20:8,132,266...8,884,900
Ensembl chr20:8,077,251...8,968,360
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G |
PLCD1 |
phospholipase C delta 1 |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of PLCD1 promoter Methamphetamine results in increased expression of PLCD1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:38,007,496...38,029,642
Ensembl chr 3:38,007,496...38,029,642
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G |
PLCD3 |
phospholipase C delta 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of PLCD3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:45,108,959...45,132,515
Ensembl chr17:45,108,959...45,133,354
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G |
PLEC |
plectin |
increases expression |
ISO |
Methamphetamine results in increased expression of PLEC mRNA |
CTD |
PMID:26307267 |
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NCBI chr 8:143,915,153...143,976,745
Ensembl chr 8:143,915,153...143,976,734
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G |
PLEKHA6 |
pleckstrin homology domain containing A6 |
increases expression |
ISO |
Methamphetamine results in increased expression of PLEKHA6 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:204,218,853...204,378,168
Ensembl chr 1:204,218,853...204,377,665
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G |
PLEKHF1 |
pleckstrin homology and FYVE domain containing 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of PLEKHF1 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of PLEKHF1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:29,665,461...29,675,477
Ensembl chr19:29,665,459...29,675,477
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G |
PLEKHG2 |
pleckstrin homology and RhoGEF domain containing G2 |
increases expression |
ISO |
Methamphetamine results in increased expression of PLEKHG2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:39,412,669...39,428,415
Ensembl chr19:39,412,669...39,428,415
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G |
PLEKHG5 |
pleckstrin homology and RhoGEF domain containing G5 |
increases expression |
ISO |
Methamphetamine results in increased expression of PLEKHG5 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:6,467,122...6,520,092
Ensembl chr 1:6,467,122...6,520,074
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G |
PLEKHJ1 |
pleckstrin homology domain containing J1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PLEKHJ1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:2,229,981...2,236,329
Ensembl chr19:2,230,084...2,237,704
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G |
PLEKHM2 |
pleckstrin homology and RUN domain containing M2 |
increases expression affects methylation |
ISO |
Methamphetamine results in increased expression of PLEKHM2 mRNA Methamphetamine affects the methylation of PLEKHM2 promoter |
CTD |
PMID:26307267 |
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NCBI chr 1:15,681,506...15,734,769
Ensembl chr 1:15,684,320...15,734,769
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G |
PLEKHN1 |
pleckstrin homology domain containing N1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PLEKHN1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:966,482...975,865
Ensembl chr 1:966,482...975,865
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G |
PLEKHO1 |
pleckstrin homology domain containing O1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PLEKHO1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:150,149,646...150,160,065
Ensembl chr 1:150,149,183...150,164,720
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G |
PLK3 |
polo like kinase 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of PLK3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:44,800,377...44,805,990
Ensembl chr 1:44,800,377...44,805,990
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G |
PLPPR2 |
phospholipid phosphatase related 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of PLPPR2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:11,355,432...11,365,698
Ensembl chr19:11,355,386...11,365,698
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G |
PMCH |
pro-melanin concentrating hormone |
affects expression multiple interactions |
ISO |
Methamphetamine affects the expression of PMCH mRNA [Methamphetamine co-treated with SCH 23390] affects the expression of PMCH mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:102,196,459...102,197,833
Ensembl chr12:102,196,459...102,197,833
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G |
PMEPA1 |
prostate transmembrane protein, androgen induced 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PMEPA1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:57,648,396...57,711,472
Ensembl chr20:57,648,392...57,711,536
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G |
PNLIP |
pancreatic lipase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PNLIP mRNA |
CTD |
PMID:15644446 |
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NCBI chr10:116,545,931...116,567,855
Ensembl chr10:116,545,931...116,567,855
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G |
PNPLA7 |
patatin like phospholipase domain containing 7 |
increases expression |
ISO |
Methamphetamine results in increased expression of PNPLA7 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:137,459,952...137,550,402
Ensembl chr 9:137,459,952...137,550,402
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G |
PODXL |
podocalyxin like |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PODXL mRNA |
CTD |
PMID:15644446 |
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NCBI chr 7:131,500,271...131,556,628
Ensembl chr 7:131,500,262...131,558,217
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G |
POLA2 |
DNA polymerase alpha 2, accessory subunit |
increases expression |
ISO |
Methamphetamine results in increased expression of POLA2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:65,261,962...65,305,985
Ensembl chr11:65,261,913...65,305,959
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G |
POLL |
DNA polymerase lambda |
decreases expression |
ISO |
Methamphetamine results in decreased expression of POLL mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:101,578,882...101,588,270
Ensembl chr10:101,578,882...101,588,270
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G |
POLR3E |
RNA polymerase III subunit E |
decreases expression |
ISO |
Methamphetamine results in decreased expression of POLR3E mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:22,297,409...22,335,096
Ensembl chr16:22,297,375...22,335,101
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G |
POLR3GL |
RNA polymerase III subunit GL |
decreases expression |
ISO |
Methamphetamine results in decreased expression of POLR3GL mRNA |
CTD |
PMID:35863504 |
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NCBI chr 1:145,964,690...145,978,848
Ensembl chr 1:145,964,690...145,978,848
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G |
POM121L12 |
POM121 transmembrane nucleoporin like 12 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of POM121L12 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:53,035,633...53,036,925
Ensembl chr 7:53,035,633...53,036,925
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G |
POU5F1 |
POU class 5 homeobox 1 |
affects response to substance |
EXP |
POU5F1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 6:31,164,337...31,170,682
Ensembl chr 6:31,164,337...31,180,731
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G |
PPARG |
peroxisome proliferator activated receptor gamma |
multiple interactions increases response to substance increases activity increases expression decreases expression |
ISO |
2-chloro-5-nitrobenzanilide promotes the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; [pioglitazone co-treated with alitretinoin] inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; ciglitazone inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine]; Ibuprofen inhibits the reaction [Methamphetamine results in decreased expression of PPARG protein]; pioglitazone inhibits the reaction [PPARG protein results in increased susceptibility to Methamphetamine] Methamphetamine results in increased activity of PPARG protein Methamphetamine results in increased expression of PPARG protein |
CTD |
PMID:17019405 PMID:18946735 |
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NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356
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G |
PPARGC1A |
PPARG coactivator 1 alpha |
increases expression |
ISO |
Methamphetamine results in increased expression of PPARGC1A mRNA |
CTD |
PMID:26307267 |
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NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089
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G |
PPIA |
peptidylprolyl isomerase A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PPIA mRNA |
CTD |
PMID:15644446 |
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NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564
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G |
PPIC |
peptidylprolyl isomerase C |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PPIC mRNA |
CTD |
PMID:36914120 |
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NCBI chr 5:123,023,250...123,036,725
Ensembl chr 5:123,023,250...123,036,725
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G |
PPIH |
peptidylprolyl isomerase H |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of PPIH promoter |
CTD |
PMID:26307267 |
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NCBI chr 1:42,658,423...42,681,654
Ensembl chr 1:42,658,335...42,676,758
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G |
PPIP5K2 |
diphosphoinositol pentakisphosphate kinase 2 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of PPIP5K2 mRNA Methamphetamine results in increased expression of PPIP5K2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:103,120,301...103,212,799
Ensembl chr 5:103,120,149...103,212,799
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G |
PPM1D |
protein phosphatase, Mg2+/Mn2+ dependent 1D |
increases expression |
ISO |
Methamphetamine results in increased expression of PPM1D mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:60,600,193...60,666,280
Ensembl chr17:60,600,193...60,666,280
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G |
PPP1R14A |
protein phosphatase 1 regulatory inhibitor subunit 14A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PPP1R14A mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:38,251,237...38,256,374
Ensembl chr19:38,251,237...38,256,532
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G |
PPP1R15A |
protein phosphatase 1 regulatory subunit 15A |
multiple interactions increases expression |
ISO |
SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP1R15A mRNA] |
CTD |
PMID:19564919 |
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NCBI chr19:48,872,421...48,876,058
Ensembl chr19:48,872,212...48,876,059
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G |
PPP1R1B |
protein phosphatase 1 regulatory inhibitor subunit 1B |
multiple interactions increases expression increases phosphorylation |
ISO |
naloxonazine inhibits the reaction [Methamphetamine results in increased phosphorylation of PPP1R1B protein] Methamphetamine results in increased expression of PPP1R1B mRNA |
CTD |
PMID:22564758 PMID:28341135 |
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NCBI chr17:39,626,707...39,636,624
Ensembl chr17:39,626,740...39,636,626
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G |
PPP1R9A |
protein phosphatase 1 regulatory subunit 9A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PPP1R9A mRNA |
CTD |
PMID:15644446 |
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NCBI chr 7:94,907,236...95,296,415
Ensembl chr 7:94,907,202...95,296,415
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G |
PPP2R3A |
protein phosphatase 2 regulatory subunit B''alpha |
increases expression |
ISO |
Methamphetamine results in increased expression of PPP2R3A mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:135,965,728...136,147,894
Ensembl chr 3:135,965,728...136,147,894
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G |
PPP3CA |
protein phosphatase 3 catalytic subunit alpha |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of PPP3CA protein SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3CA protein] |
CTD |
PMID:15644446 |
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NCBI chr 4:101,023,418...101,347,526
Ensembl chr 4:101,023,409...101,348,278
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G |
PPP3CB |
protein phosphatase 3 catalytic subunit beta |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of PPP3CB protein SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3CB protein] |
CTD |
PMID:15644446 |
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NCBI chr10:73,436,433...73,496,024
Ensembl chr10:73,436,433...73,496,024
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G |
PPP3R1 |
protein phosphatase 3 regulatory subunit B, alpha |
affects expression |
ISO |
Methamphetamine affects the expression of PPP3R1 protein |
CTD |
PMID:17904249 |
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NCBI chr 2:68,178,857...68,252,532
Ensembl chr 2:68,178,857...68,256,237
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G |
PPP3R2 |
protein phosphatase 3 regulatory subunit B, beta |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of PPP3R2 protein SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of PPP3R2 protein] |
CTD |
PMID:15644446 |
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NCBI chr 9:101,591,604...101,594,969
Ensembl chr 9:101,591,604...101,595,021
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G |
PPP6R1 |
protein phosphatase 6 regulatory subunit 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PPP6R1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:55,228,218...55,259,017
Ensembl chr19:55,229,779...55,259,017
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G |
PPP6R2 |
protein phosphatase 6 regulatory subunit 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of PPP6R2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr22:50,330,774...50,445,090
Ensembl chr22:50,343,304...50,445,090
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G |
PPTC7 |
protein phosphatase targeting COQ7 |
increases expression |
ISO |
Methamphetamine results in increased expression of PPTC7 mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:110,533,245...110,583,318
Ensembl chr12:110,533,245...110,583,318
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G |
PRDM1 |
PR/SET domain 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PRDM1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:105,992,690...106,109,938
Ensembl chr 6:105,993,463...106,109,939
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G |
PRDM16 |
PR/SET domain 16 |
affects methylation increases expression |
ISO |
Methamphetamine affects the methylation of PRDM16 promoter Methamphetamine results in increased expression of PRDM16 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:3,069,203...3,438,621
Ensembl chr 1:3,069,168...3,438,621
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G |
PRDM2 |
PR/SET domain 2 |
affects response to substance |
EXP |
PRDM2 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 1:13,700,188...13,825,079
Ensembl chr 1:13,700,188...13,825,079
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G |
PRDX2 |
peroxiredoxin 2 |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of PRDX2 protein Methamphetamine results in decreased expression of PRDX2 protein |
CTD |
PMID:16181420 PMID:19826936 |
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NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800
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G |
PRDX5 |
peroxiredoxin 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of PRDX5 mRNA |
CTD |
PMID:19149911 |
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NCBI chr11:64,318,121...64,321,811
Ensembl chr11:64,318,121...64,321,811
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G |
PRG4 |
proteoglycan 4 |
affects expression multiple interactions |
ISO |
Methamphetamine affects the expression of PRG4 mRNA [Methamphetamine co-treated with SCH 23390] affects the expression of PRG4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:186,296,273...186,314,567
Ensembl chr 1:186,296,279...186,314,567
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G |
PRICKLE3 |
prickle planar cell polarity protein 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of PRICKLE3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr X:49,174,802...49,186,373
Ensembl chr X:49,174,802...49,186,528
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G |
PRKCA |
protein kinase C alpha |
multiple interactions increases expression |
EXP |
1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of PRKCA mRNA]; 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of PRKCA protein] Methamphetamine results in increased expression of PRKCA mRNA; Methamphetamine results in increased expression of PRKCA protein |
CTD |
PMID:33421459 |
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NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743
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G |
PRKCD |
protein kinase C delta |
affects localization multiple interactions affects response to substance increases expression increases response to substance |
ISO EXP |
Methamphetamine affects the localization of PRKCD protein ginsenoside Re inhibits the reaction [Methamphetamine affects the localization of PRKCD protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of and results in increased cleavage of PRKCD protein]; Methamphetamine results in increased expression of and results in increased cleavage of PRKCD protein; PRKCD protein affects the reaction [Methamphetamine affects the localization of PRKCD protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in increased activity of SOD1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased activity of SOD2 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of and results in increased cleavage of PRKCD protein] PRKCD protein affects the susceptibility to Methamphetamine Methamphetamine results in increased expression of PRKCD protein PRKCD results in increased susceptibility to Methamphetamine [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased activity of TH protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of DAT protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in increased metabolism of Dopamine]; [rottlerin results in decreased activity of PRKCD protein] which results in decreased susceptibility to Methamphetamine; ginsenoside Re inhibits the reaction [Methamphetamine affects the localization of PRKCD protein]; Methamphetamine promotes the reaction [PRKCD protein modified form binds to EPHX1 protein]; Methamphetamine results in increased cleavage of and results in increased phosphorylation of PRKCD protein; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of CAT protein]]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]]; PRKCD affects the reaction [Methamphetamine results in increased activity of CAT protein]; PRKCD affects the reaction [Methamphetamine results in increased activity of SOD1 protein]; PRKCD affects the reaction [Methamphetamine results in increased activity of SOD2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased activity of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of BCL2L1 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of DAT protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of SLC18A2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; PRKCD protein affects the reaction [Methamphetamine results in increased expression of EPHX1 protein]; PRKCD protein affects the reaction [Methamphetamine results in increased metabolism of Dopamine] |
CTD |
PMID:22512859 PMID:24430743 PMID:25523949 PMID:31422080 |
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NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717
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G |
PRKCE |
protein kinase C epsilon |
multiple interactions increases expression |
ISO |
Lithium inhibits the reaction [Methamphetamine results in increased expression of PRKCE mRNA] |
CTD |
PMID:19149911 |
|
NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990
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G |
PRKD2 |
protein kinase D2 |
increases expression |
ISO |
Methamphetamine results in increased expression of PRKD2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr19:46,674,316...46,717,114
Ensembl chr19:46,674,275...46,717,127
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G |
PRKG1 |
protein kinase cGMP-dependent 1 |
affects response to substance |
EXP |
PRKG1 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423
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G |
PRKN |
parkin RBR E3 ubiquitin protein ligase |
decreases expression multiple interactions |
ISO EXP |
Methamphetamine results in decreased expression of PRKN protein CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; PRKN protein inhibits the reaction [Methamphetamine results in decreased expression of PRKN protein]; PRKN protein inhibits the reaction [Methamphetamine results in increased expression of SNCA protein]; TRIB3 protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein] |
CTD |
PMID:28661099 PMID:31059759 |
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NCBI chr 6:161,347,417...162,727,766
Ensembl chr 6:161,347,417...162,727,775
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G |
PRKX |
protein kinase cAMP-dependent X-linked catalytic subunit |
increases expression |
ISO |
Methamphetamine results in increased expression of PRKX mRNA |
CTD |
PMID:19564919 |
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NCBI chr X:3,604,340...3,713,649
Ensembl chr X:3,604,340...3,713,649
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G |
PRL |
prolactin |
affects expression |
EXP |
Methamphetamine affects the expression of PRL protein |
CTD |
PMID:21142706 |
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NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826
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G |
PRODH |
proline dehydrogenase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PRODH mRNA |
CTD |
PMID:26307267 |
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NCBI chr22:18,912,781...18,936,553
Ensembl chr22:18,912,777...18,936,553
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G |
PROK2 |
prokineticin 2 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of PROK2 mRNA Methamphetamine results in increased expression of PROK2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:71,771,655...71,785,148
Ensembl chr 3:71,771,655...71,785,206
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G |
PROKR2 |
prokineticin receptor 2 |
affects response to substance |
EXP |
PROKR2 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:20576534 |
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NCBI chr20:5,299,218...5,316,954
Ensembl chr20:5,299,218...5,316,954
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G |
PROM1 |
prominin 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PROM1 mRNA Methamphetamine results in decreased expression of PROM1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:15,968,228...16,084,023
Ensembl chr 4:15,963,076...16,084,378
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G |
PROX2 |
prospero homeobox 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PROX2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr14:74,853,033...74,876,145
Ensembl chr14:74,852,871...74,876,154
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G |
PRR13 |
proline rich 13 |
increases expression |
ISO |
Methamphetamine results in increased expression of PRR13 mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:53,441,734...53,446,638
Ensembl chr12:53,441,678...53,446,645
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G |
PRR14L |
proline rich 14 like |
increases expression |
ISO |
Methamphetamine results in increased expression of PRR14L mRNA |
CTD |
PMID:28341135 |
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NCBI chr22:31,681,347...31,750,132
Ensembl chr22:31,676,256...31,750,140
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G |
PRR5L |
proline rich 5 like |
increases expression |
ISO |
Methamphetamine results in increased expression of PRR5L mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:36,296,288...36,465,204
Ensembl chr11:36,296,288...36,465,204
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G |
PRRC2C |
proline rich coiled-coil 2C |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of PRRC2C promoter Methamphetamine results in increased expression of PRRC2C mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:171,485,530...171,593,511
Ensembl chr 1:171,485,530...171,593,511
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G |
PRUNE2 |
prune homolog 2 with BCH domain |
increases expression |
ISO |
Methamphetamine results in increased expression of PRUNE2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:76,611,376...76,906,114
Ensembl chr 9:76,611,376...76,906,114
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G |
PSAT1 |
phosphoserine aminotransferase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PSAT1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 9:78,297,125...78,330,093
Ensembl chr 9:78,297,125...78,330,093
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G |
PSD3 |
pleckstrin and Sec7 domain containing 3 |
affects response to substance increases expression |
EXP ISO |
PSD3 gene SNP affects the susceptibility to Methamphetamine Methamphetamine results in increased expression of PSD3 mRNA |
CTD |
PMID:18316681 PMID:26307267 |
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NCBI chr 8:18,527,303...19,084,805
Ensembl chr 8:18,527,303...19,084,730
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G |
PSMA1 |
proteasome 20S subunit alpha 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PSMA1 protein |
CTD |
PMID:19826936 |
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NCBI chr11:14,504,876...14,643,662
Ensembl chr11:14,504,874...14,643,635
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G |
PSMA2 |
proteasome 20S subunit alpha 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PSMA2 protein |
CTD |
PMID:19826936 |
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NCBI chr 7:42,916,861...42,932,174
Ensembl chr 7:42,916,828...42,932,185
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G |
PSMA5 |
proteasome 20S subunit alpha 5 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PSMA5 mRNA |
CTD |
PMID:15644446 |
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NCBI chr 1:109,399,042...109,426,448
Ensembl chr 1:109,399,042...109,426,448
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G |
PSMC3 |
proteasome 26S subunit, ATPase 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PSMC3 protein |
CTD |
PMID:19826936 |
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NCBI chr11:47,418,775...47,426,439
Ensembl chr11:47,418,769...47,426,473
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G |
PTEN |
phosphatase and tensin homolog |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of PTEN mRNA; Methamphetamine results in increased expression of PTEN protein Luteolin inhibits the reaction [Methamphetamine results in increased expression of PTEN protein] |
CTD |
PMID:19564919 PMID:32035215 |
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NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930
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G |
PTGIS |
prostaglandin I2 synthase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PTGIS mRNA |
CTD |
PMID:36914120 |
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NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137
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G |
PTGS1 |
prostaglandin-endoperoxide synthase 1 |
multiple interactions increases response to substance |
EXP |
[[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine; Aspirin inhibits the reaction [[Arachidonic Acid results in increased activity of PTGS1 protein] which results in increased susceptibility to Methamphetamine]; Aspirin inhibits the reaction [PTGS1 protein results in increased susceptibility to Methamphetamine] |
CTD |
PMID:21163909 |
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NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703
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G |
PTGS2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression increases response to substance |
EXP ISO |
[[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine] which results in increased abundance of 8-Hydroxy-2'-Deoxyguanosine; [Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine; Aspirin inhibits the reaction [[Arachidonic Acid results in increased activity of PTGS2 protein] which results in increased susceptibility to Methamphetamine]; Aspirin inhibits the reaction [PTGS2 protein results in increased susceptibility to Methamphetamine] Methamphetamine results in increased expression of PTGS2 mRNA Methamphetamine results in increased expression of PTGS2 protein |
CTD |
PMID:10698006 PMID:15644446 PMID:15718289 PMID:19564919 PMID:21163909 PMID:25290377 More...
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NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922
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G |
PTH1R |
parathyroid hormone 1 receptor |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PTH1R mRNA Methamphetamine results in decreased expression of PTH1R mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:46,877,721...46,903,799
Ensembl chr 3:46,877,721...46,903,799
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G |
PTPN5 |
protein tyrosine phosphatase non-receptor type 5 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of PTPN5 protein alternative form 3-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine inhibits the reaction [Methamphetamine results in decreased expression of PTPN5 protein alternative form] |
CTD |
PMID:23711322 |
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NCBI chr11:18,727,928...18,792,721
Ensembl chr11:18,727,928...18,792,721
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G |
PTPRS |
protein tyrosine phosphatase receptor type S |
increases expression |
ISO |
Methamphetamine results in increased expression of PTPRS mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:5,205,508...5,340,812
Ensembl chr19:5,158,495...5,340,812
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G |
PUM1 |
pumilio RNA binding family member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of PUM1 mRNA |
CTD |
PMID:15542705 |
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NCBI chr 1:30,931,506...31,065,717
Ensembl chr 1:30,931,506...31,065,991
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G |
PURB |
purine rich element binding protein B |
increases expression |
ISO |
Methamphetamine results in increased expression of PURB mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:44,876,299...44,885,530
Ensembl chr 7:44,876,299...44,885,530
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G |
PUSL1 |
pseudouridine synthase like 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of PUSL1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:1,308,597...1,311,677
Ensembl chr 1:1,308,597...1,311,677
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G |
PVR |
PVR cell adhesion molecule |
increases expression |
ISO |
Methamphetamine results in increased expression of PVR mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:44,643,910...44,666,162
Ensembl chr19:44,643,798...44,666,162
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G |
PXN |
paxillin |
increases expression |
ISO |
Methamphetamine results in increased expression of PXN mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:120,210,447...120,265,730
Ensembl chr12:120,210,439...120,265,771
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G |
PYCARD |
PYD and CARD domain containing |
multiple interactions increases expression decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of PYCARD mRNA Methamphetamine promotes the reaction [PYCARD protein binds to NLRP3 protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased cleavage of CASP1 protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; PYCARD protein promotes the reaction [Methamphetamine results in increased expression of NLRP3 protein] Methamphetamine results in increased expression of PYCARD protein Methamphetamine results in decreased expression of PYCARD mRNA |
CTD |
PMID:19564919 PMID:30394308 |
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NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450
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G |
QARS1 |
glutaminyl-tRNA synthetase 1 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of QARS1 mRNA Lithium inhibits the reaction [Methamphetamine results in decreased expression of QARS1 mRNA]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of QARS1 mRNA] |
CTD |
PMID:19149911 |
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NCBI chr 3:49,095,932...49,104,757
Ensembl chr 3:49,095,932...49,105,130
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G |
QPRT |
quinolinate phosphoribosyltransferase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of QPRT mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:29,679,008...29,698,699
Ensembl chr16:29,663,279...29,698,699
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G |
RAB30 |
RAB30, member RAS oncogene family |
increases expression |
ISO |
Methamphetamine results in increased expression of RAB30 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:82,973,133...83,071,897
Ensembl chr11:82,973,133...83,071,923
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G |
RAB3D |
RAB3D, member RAS oncogene family |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RAB3D mRNA Methamphetamine results in decreased expression of RAB3D mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:11,322,068...11,339,657
Ensembl chr19:11,322,068...11,346,270
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G |
RAB5A |
RAB5A, member RAS oncogene family |
increases expression |
ISO |
Methamphetamine results in increased expression of RAB5A protein |
CTD |
PMID:34374793 |
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NCBI chr 3:19,947,097...19,985,175
Ensembl chr 3:19,947,097...19,985,175
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G |
RAB7A |
RAB7A, member RAS oncogene family |
increases expression |
ISO |
Methamphetamine results in increased expression of RAB7 mRNA; Methamphetamine results in increased expression of RAB7 protein |
CTD |
PMID:34374793 |
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NCBI chr 3:128,726,183...128,814,798
Ensembl chr 3:128,693,669...128,825,942
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G |
RABEP1 |
rabaptin, RAB GTPase binding effector protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of RABEP1 protein |
CTD |
PMID:19826936 |
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NCBI chr17:5,282,284...5,386,340
Ensembl chr17:5,282,265...5,386,340
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G |
RABIF |
RAB interacting factor |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of RABIF protein Methamphetamine results in decreased expression of RABIF mRNA |
CTD |
PMID:19564919 PMID:19826936 |
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NCBI chr 1:202,878,282...202,889,149
Ensembl chr 1:202,878,282...202,889,149
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G |
RAD18 |
RAD18 E3 ubiquitin protein ligase |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RAD18 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:8,877,075...8,963,472
Ensembl chr 3:8,775,402...8,963,773
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G |
RAD51AP1 |
RAD51 associated protein 1 |
decreases expression |
EXP |
Methamphetamine results in decreased expression of RAD51AP1 mRNA |
CTD |
PMID:25290377 |
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NCBI chr12:4,538,890...4,560,047
Ensembl chr12:4,538,798...4,560,047
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G |
RAD52 |
RAD52 homolog, DNA repair protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RAD52 mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:911,736...991,122
Ensembl chr12:911,736...990,053
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G |
RAD54L |
RAD54 like |
increases methylation |
ISO |
Methamphetamine results in increased methylation of RAD54L promoter |
CTD |
PMID:26307267 |
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NCBI chr 1:46,247,688...46,278,473
Ensembl chr 1:46,246,461...46,278,480
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G |
RALGAPA1 |
Ral GTPase activating protein catalytic subunit alpha 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of RALGAPA1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr14:35,538,356...35,809,295
Ensembl chr14:35,538,352...35,809,304
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G |
RALGAPA2 |
Ral GTPase activating protein catalytic subunit alpha 2 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of RALGAPA2 promoter |
CTD |
PMID:26307267 |
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NCBI chr20:20,389,530...20,712,644
Ensembl chr20:20,389,530...20,712,644
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G |
RALGPS2 |
Ral GEF with PH domain and SH3 binding motif 2 |
decreases expression decreases methylation |
ISO |
Methamphetamine results in decreased expression of RALGPS2 mRNA Methamphetamine results in decreased methylation of RALGPS2 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 1:178,725,244...178,921,840
Ensembl chr 1:178,725,165...178,921,842
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G |
RALY |
RALY heterogeneous nuclear ribonucleoprotein |
affects response to substance |
EXP |
RALY gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr20:33,993,911...34,084,884
Ensembl chr20:33,993,646...34,108,308
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G |
RAMP2 |
receptor activity modifying protein 2 |
decreases expression decreases methylation increases expression |
ISO |
Methamphetamine results in decreased expression of RAMP2 mRNA Methamphetamine results in decreased methylation of RAMP2 promoter Methamphetamine results in increased expression of RAMP2 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr17:42,761,227...42,763,041
Ensembl chr17:42,758,447...42,763,041
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G |
RANBP3 |
RAN binding protein 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of RANBP3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:5,916,139...5,978,140
Ensembl chr19:5,916,139...5,978,142
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G |
RAPGEF3 |
Rap guanine nucleotide exchange factor 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of RAPGEF3 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:47,734,363...47,758,880
Ensembl chr12:47,734,363...47,771,040
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G |
RAPGEF5 |
Rap guanine nucleotide exchange factor 5 |
affects response to substance |
EXP |
RAPGEF5 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 7:22,118,236...22,357,154
Ensembl chr 7:22,118,236...22,357,154
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G |
RARG |
retinoic acid receptor gamma |
increases expression |
ISO |
Methamphetamine results in increased expression of RARG mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:53,210,569...53,232,209
Ensembl chr12:53,210,567...53,232,980
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G |
RASA4B |
RAS p21 protein activator 4B |
increases expression |
ISO |
Methamphetamine results in increased expression of RASA4 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:102,479,976...102,517,777
Ensembl chr 7:102,479,976...102,517,777
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G |
RASD1 |
ras related dexamethasone induced 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of RASD1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:17,494,437...17,496,395
Ensembl chr17:17,494,437...17,496,395
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G |
RASGRP1 |
RAS guanyl releasing protein 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RASGRP1 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr15:38,488,103...38,564,814
Ensembl chr15:38,488,103...38,565,575
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G |
RASGRP2 |
RAS guanyl releasing protein 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of RASGRP2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:64,726,911...64,745,456
Ensembl chr11:64,726,911...64,745,456
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G |
RASGRP3 |
RAS guanyl releasing protein 3 |
increases expression |
EXP |
Methamphetamine results in increased expression of RASGRP3 mRNA |
CTD |
PMID:25290377 |
|
NCBI chr 2:33,436,348...33,564,731
Ensembl chr 2:33,436,324...33,564,750
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G |
RASL11A |
RAS like family 11 member A |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of RASL11A mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of RASL11A mRNA |
CTD |
PMID:19564919 |
|
NCBI chr13:27,270,830...27,275,192
Ensembl chr13:27,270,830...27,275,192
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G |
RASL11B |
RAS like family 11 member B |
increases expression |
ISO |
Methamphetamine results in increased expression of RASL11B mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 4:52,862,317...52,866,835
Ensembl chr 4:52,862,317...52,866,835
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G |
RASSF9 |
Ras association domain family member 9 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of RASSF9 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of RASSF9 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr12:85,800,703...85,836,409
Ensembl chr12:85,800,703...85,836,409
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G |
RBFOX3 |
RNA binding fox-1 homolog 3 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of RBFOX3 protein SNCA gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of RBFOX3 protein] |
CTD |
PMID:29467000 PMID:32278788 |
|
NCBI chr17:79,089,345...79,665,571
Ensembl chr17:79,089,345...79,611,051
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G |
RBM20 |
RNA binding motif protein 20 |
increases expression |
ISO |
Methamphetamine results in increased expression of RBM20 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:110,643,245...110,839,468
Ensembl chr10:110,644,336...110,839,468
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G |
RBM25 |
RNA binding motif protein 25 |
increases expression |
ISO |
Methamphetamine results in increased expression of RBM25 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr14:73,058,534...73,123,899
Ensembl chr14:73,058,532...73,123,899
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G |
RBM28 |
RNA binding motif protein 28 |
increases expression |
ISO |
Methamphetamine results in increased expression of RBM28 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:128,297,685...128,343,908
Ensembl chr 7:128,297,685...128,343,908
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G |
RBM3 |
RNA binding motif protein 3 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of RBM3 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of RBM3 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
|
NCBI chr X:48,574,484...48,581,162
Ensembl chr X:48,574,449...48,581,162
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G |
RBM43 |
RNA binding motif protein 43 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RBM43 mRNA Methamphetamine results in decreased expression of RBM43 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 2:151,247,940...151,261,863
Ensembl chr 2:151,247,940...151,261,863
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G |
RBM5 |
RNA binding motif protein 5 |
increases expression decreases methylation |
ISO |
Methamphetamine results in increased expression of RBM5 mRNA Methamphetamine results in decreased methylation of RBM5 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 3:50,088,919...50,119,021
Ensembl chr 3:50,088,919...50,119,021
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G |
RBP7 |
retinol binding protein 7 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RBP7 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 1:9,997,228...10,016,021
Ensembl chr 1:9,997,206...10,016,021
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RCAN1 |
regulator of calcineurin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of RCAN1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr21:34,516,442...34,615,113
Ensembl chr21:34,513,142...34,615,113
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RELA |
RELA proto-oncogene, NF-kB subunit |
affects response to substance increases phosphorylation increases expression increases activity multiple interactions affects localization |
ISO EXP |
RELA mRNA affects the susceptibility to Methamphetamine Methamphetamine results in increased phosphorylation of RELA protein Methamphetamine results in increased expression of RELA mRNA; Methamphetamine results in increased expression of RELA protein Methamphetamine results in increased activity of RELA protein [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of RELA mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of RELA protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]; GPX1 protein affects the reaction [Methamphetamine results in increased activity of RELA protein]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased phosphorylation of RELA protein]]; Methamphetamine results in increased expression of and results in increased phosphorylation of RELA protein; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of RELA protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of RELA protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of RELA mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of RELA protein] GATA4 protein affects the reaction [Methamphetamine results in increased phosphorylation of RELA protein]; Lactulose inhibits the reaction [Methamphetamine results in increased expression of RELA protein] Methamphetamine affects the localization of RELA protein luzindole inhibits the reaction [Melatonin inhibits the reaction [Methamphetamine affects the localization of RELA protein]]; Melatonin inhibits the reaction [Methamphetamine affects the localization of RELA protein]; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; RELA protein affects the reaction [Methamphetamine results in increased cleavage of CASP9 protein]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 mRNA]; RELA protein affects the reaction [Methamphetamine results in increased expression of DDIT3 protein] |
CTD |
PMID:19689456 PMID:26283214 PMID:27323860 PMID:30450033 PMID:32768653 PMID:32916201 PMID:34082047 PMID:35390362 PMID:35688268 PMID:36720452 PMID:36914120 More...
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NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090
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G |
REM2 |
RRAD and GEM like GTPase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of REM2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:22,883,222...22,887,678
Ensembl chr14:22,883,222...22,887,678
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G |
RENBP |
renin binding protein |
increases expression |
EXP |
Methamphetamine results in increased expression of RENBP mRNA |
CTD |
PMID:25290377 |
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NCBI chr X:153,935,269...153,944,643
Ensembl chr X:153,935,269...153,944,687
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G |
REXO1 |
RNA exonuclease 1 homolog |
increases expression |
ISO |
Methamphetamine results in increased expression of REXO1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:1,815,248...1,848,483
Ensembl chr19:1,815,248...1,848,483
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G |
RFPL4A |
ret finger protein like 4A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RFPL4 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:55,757,294...55,763,421
Ensembl chr19:55,759,097...55,763,421
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G |
RGCC |
regulator of cell cycle |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RGCC mRNA |
CTD |
PMID:36914120 |
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NCBI chr13:41,457,550...41,470,871
Ensembl chr13:41,457,550...41,470,871
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G |
RGL2 |
ral guanine nucleotide dissociation stimulator like 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of RGL2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:33,291,654...33,301,612
Ensembl chr 6:33,291,654...33,298,942
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G |
RGS1 |
regulator of G protein signaling 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of RGS1 mRNA [Methamphetamine co-treated with SCH 23390] affects the expression of RGS1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:192,575,773...192,580,024
Ensembl chr 1:192,575,763...192,580,024
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G |
RGS17 |
regulator of G protein signaling 17 |
affects response to substance |
EXP |
RGS17 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 6:153,004,459...153,131,282
Ensembl chr 6:153,004,459...153,131,282
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G |
RGS2 |
regulator of G protein signaling 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of RGS2 mRNA |
CTD |
PMID:10098858 PMID:19564919 |
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NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275
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G |
RGS4 |
regulator of G protein signaling 4 |
affects expression |
ISO |
Methamphetamine affects the expression of RGS4 mRNA |
CTD |
PMID:19126440 |
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NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802
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G |
RGS5 |
regulator of G protein signaling 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of RGS5 mRNA |
CTD |
PMID:32035215 |
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NCBI chr 1:163,142,299...163,321,735
Ensembl chr 1:163,111,121...163,321,791
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G |
RHBDF1 |
rhomboid 5 homolog 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RHBDF1 mRNA Methamphetamine results in decreased expression of RHBDF1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:58,059...76,360
Ensembl chr16:58,059...76,355
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G |
RHOB |
ras homolog family member B |
increases expression |
ISO |
Methamphetamine results in increased expression of RHOB mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:20,447,074...20,449,440
Ensembl chr 2:20,447,074...20,449,440
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G |
RHOD |
ras homolog family member D |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] affects the expression of RHOD mRNA Methamphetamine results in increased expression of RHOD mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:67,056,847...67,072,017
Ensembl chr11:67,056,847...67,072,017
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G |
RIGI |
RNA sensor RIG-I |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of RIGI mRNA Methamphetamine results in decreased expression of RIGI mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:32,455,302...32,526,196
Ensembl chr 9:32,455,302...32,526,208
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G |
RIMS2 |
regulating synaptic membrane exocytosis 2 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of RIMS2 mRNA Methamphetamine results in increased expression of RIMS2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 8:103,500,610...104,256,094
Ensembl chr 8:103,500,610...104,254,430
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G |
RIPOR2 |
RHO family interacting cell polarization regulator 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of RIPOR2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:24,804,284...25,042,168
Ensembl chr 6:24,804,282...25,042,170
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G |
RIPPLY2 |
ripply transcriptional repressor 2 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of RIPPLY2 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of RIPPLY2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:83,853,229...83,857,515
Ensembl chr 6:83,853,360...83,857,515
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G |
RLF |
RLF zinc finger |
increases expression |
ISO |
Methamphetamine results in increased expression of RLF mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:40,161,387...40,240,921
Ensembl chr 1:40,161,387...40,240,921
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G |
RMND1 |
required for meiotic nuclear division 1 homolog |
increases expression |
ISO |
Methamphetamine results in increased expression of RMND1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:151,404,762...151,452,126
Ensembl chr 6:151,398,898...151,452,158
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G |
RNF113A |
ring finger protein 113A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RNF113A1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr X:119,870,475...119,871,733
Ensembl chr X:119,870,475...119,871,733
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G |
RNF123 |
ring finger protein 123 |
increases expression |
ISO |
Methamphetamine results in increased expression of RNF123 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:49,689,557...49,721,529
Ensembl chr 3:49,689,538...49,721,529
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G |
RNF13 |
ring finger protein 13 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RNF13 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:149,812,688...149,962,139
Ensembl chr 3:149,812,770...149,962,139
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G |
RNF225 |
ring finger protein 225 |
affects expression multiple interactions |
ISO |
Methamphetamine affects the expression of RNF225 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of RNF225 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:58,395,656...58,397,079
Ensembl chr19:58,395,656...58,397,079
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G |
RNF31 |
ring finger protein 31 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RNF31 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:24,146,875...24,160,655
Ensembl chr14:24,146,683...24,160,660
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G |
RORC |
RAR related orphan receptor C |
decreases expression increases expression |
ISO |
Methamphetamine results in decreased expression of RORC mRNA Methamphetamine results in increased expression of RORC mRNA |
CTD |
PMID:35863504 PMID:36914120 |
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NCBI chr 1:151,806,071...151,831,802
Ensembl chr 1:151,806,071...151,831,845
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G |
RPL15 |
ribosomal protein L15 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RPL15 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:23,916,545...23,924,631
Ensembl chr 3:23,916,591...23,924,374
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G |
RPL30 |
ribosomal protein L30 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RPL30 mRNA |
CTD |
PMID:15644446 |
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NCBI chr 8:98,041,721...98,045,545
Ensembl chr 8:98,024,851...98,046,469
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G |
RPL39L |
ribosomal protein L39 like |
increases expression |
ISO |
Methamphetamine results in increased expression of RPL39L mRNA |
CTD |
PMID:26307267 |
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NCBI chr 3:187,120,948...187,139,496
Ensembl chr 3:187,120,948...187,180,908
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G |
RPLP2 |
ribosomal protein lateral stalk subunit P2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RPLP2 mRNA |
CTD |
PMID:32035215 |
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NCBI chr11:809,967...812,876
Ensembl chr11:809,965...812,880
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G |
RPS27A |
ribosomal protein S27a |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RPS27A mRNA |
CTD |
PMID:15644446 |
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NCBI chr 2:55,231,903...55,235,853
Ensembl chr 2:55,231,903...55,235,853
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G |
RPS6 |
ribosomal protein S6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RPS6 mRNA |
CTD |
PMID:15644446 |
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NCBI chr 9:19,375,715...19,380,236
Ensembl chr 9:19,375,715...19,380,236
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G |
RPS6KB1 |
ribosomal protein S6 kinase B1 |
decreases phosphorylation |
ISO |
Methamphetamine results in decreased phosphorylation of RPS6KB1 protein |
CTD |
PMID:34374793 |
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NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574
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G |
RPS6KB2 |
ribosomal protein S6 kinase B2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RPS6KB2 mRNA |
CTD |
PMID:32035215 |
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NCBI chr11:67,428,494...67,435,401
Ensembl chr11:67,428,460...67,435,401
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G |
RPUSD3 |
RNA pseudouridine synthase D3 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of RPUSD3 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of RPUSD3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:9,837,849...9,844,008
Ensembl chr 3:9,837,849...9,844,602
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G |
RRM2 |
ribonucleotide reductase regulatory subunit M2 |
decreases expression |
EXP ISO |
Methamphetamine results in decreased expression of RRM2 mRNA Methamphetamine results in decreased expression of RRM2 mRNA; Methamphetamine results in decreased expression of RRM2 protein |
CTD |
PMID:25290377 PMID:28341135 |
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NCBI chr 2:10,122,568...10,211,010
Ensembl chr 2:10,120,698...10,211,725
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G |
RSRP1 |
arginine and serine rich protein 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RSRP1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 1:25,242,249...25,338,254
Ensembl chr 1:25,242,249...25,338,213
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G |
RTKN2 |
rhotekin 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RTKN2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:62,183,900...62,268,844
Ensembl chr10:62,183,035...62,268,844
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G |
RTN4RL1 |
reticulon 4 receptor like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of RTN4RL1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr17:1,934,677...2,025,334
Ensembl chr17:1,934,677...2,025,334
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G |
RTP1 |
receptor transporter protein 1 |
affects expression multiple interactions |
ISO |
Methamphetamine affects the expression of RTP1 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of RTP1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:187,197,486...187,201,462
Ensembl chr 3:187,197,486...187,201,462
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G |
RWDD3 |
RWD domain containing 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of RWDD3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:95,234,155...95,247,225
Ensembl chr 1:95,234,210...95,247,225
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G |
RYR2 |
ryanodine receptor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of RYR2 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988
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G |
S100A11 |
S100 calcium binding protein A11 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of S100A11 mRNA Methamphetamine results in decreased expression of S100A11 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:152,032,506...152,037,004
Ensembl chr 1:152,032,506...152,047,907
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G |
SAP18 |
Sin3A associated protein 18 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SAP18 mRNA |
CTD |
PMID:32035215 |
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NCBI chr13:21,140,119...21,149,097
Ensembl chr13:21,140,119...21,149,097
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G |
SARM1 |
sterile alpha and TIR motif containing 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SARM1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:28,371,694...28,404,049
Ensembl chr17:28,364,356...28,404,049
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G |
SARS2 |
seryl-tRNA synthetase 2, mitochondrial |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SARS2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:38,915,266...38,930,763
Ensembl chr19:38,915,266...38,930,763
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G |
SAXO1 |
stabilizer of axonemal microtubules 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SAXO1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 9:18,927,650...19,049,339
Ensembl chr 9:18,858,906...19,049,358
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G |
SBF1 |
SET binding factor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SBF1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr22:50,445,000...50,475,035
Ensembl chr22:50,443,219...50,483,923
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G |
SCAND1 |
SCAN domain containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SCAND1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr20:35,953,624...35,959,472
Ensembl chr20:35,953,617...35,959,472
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G |
SCARF2 |
scavenger receptor class F member 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SCARF2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr22:20,424,584...20,437,825
Ensembl chr22:20,424,584...20,437,826
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G |
SCG2 |
secretogranin II |
increases expression |
ISO |
Methamphetamine results in increased expression of SCG2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:223,596,940...223,602,361
Ensembl chr 2:223,596,940...223,602,361
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G |
SCN5A |
sodium voltage-gated channel alpha subunit 5 |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of SCN5A promoter Methamphetamine results in increased expression of SCN5A mRNA |
CTD |
PMID:26307267 PMID:35863504 |
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NCBI chr 3:38,548,062...38,649,687
Ensembl chr 3:38,548,057...38,649,687
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G |
SCRG1 |
stimulator of chondrogenesis 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SCRG1 mRNA |
CTD |
PMID:28619521 |
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NCBI chr 4:173,384,701...173,519,144
Ensembl chr 4:173,384,701...173,406,380
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G |
SCRT2 |
scratch family transcriptional repressor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of SCRT2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:661,596...675,802
Ensembl chr20:661,596...675,802
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G |
SEC14L1 |
SEC14 like lipid binding 1 |
affects methylation increases expression |
ISO |
Methamphetamine affects the methylation of SEC14L1 promoter Methamphetamine results in increased expression of SEC14L1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:77,088,685...77,217,101
Ensembl chr17:77,088,749...77,217,101
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G |
SEC24A |
SEC24 homolog A, COPII coat complex component |
increases expression |
ISO |
Methamphetamine results in increased expression of SEC24A mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:134,648,382...134,727,909
Ensembl chr 5:134,648,785...134,727,909
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G |
SECISBP2 |
SECIS binding protein 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of SECISBP2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:89,318,500...89,367,117
Ensembl chr 9:89,318,500...89,359,663
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G |
SELENOI |
selenoprotein I |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SELENOI mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:26,346,143...26,395,885
Ensembl chr 2:26,308,547...26,395,885
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G |
SELENOP |
selenoprotein P |
increases expression |
ISO |
Methamphetamine results in increased expression of SELENOP mRNA |
CTD |
PMID:32035215 |
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NCBI chr 5:42,799,880...42,811,892
Ensembl chr 5:42,799,880...42,887,392
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G |
SEPTIN3 |
septin 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SEPTIN3 protein |
CTD |
PMID:19826936 |
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NCBI chr22:41,969,443...41,998,221
Ensembl chr22:41,969,443...41,998,221
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G |
SEPTIN5 |
septin 5 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SEPTIN5 protein |
CTD |
PMID:19826936 |
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NCBI chr22:19,714,503...19,723,319
Ensembl chr22:19,714,503...19,724,224
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G |
SERPINA5 |
serpin family A member 5 |
affects response to substance |
EXP |
SERPINA5 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr14:94,581,426...94,593,118
Ensembl chr14:94,561,442...94,593,118
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G |
SERPINB9 |
serpin family B member 9 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SERPINB9 mRNA Methamphetamine results in decreased expression of SERPINB9 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:2,887,270...2,903,309
Ensembl chr 6:2,887,270...2,903,309
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G |
SERPINE1 |
serpin family E member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SERPINE1 mRNA |
CTD |
PMID:12766323 |
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NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
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G |
SERPINF1 |
serpin family F member 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SERPINF1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565
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G |
SERTAD1 |
SERTA domain containing 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of SERTAD1 mRNA Methamphetamine results in increased expression of SERTAD1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:40,421,589...40,425,992
Ensembl chr19:40,421,589...40,425,992
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G |
SESN2 |
sestrin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of SESN2 mRNA |
CTD |
PMID:28619521 |
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NCBI chr 1:28,259,518...28,282,491
Ensembl chr 1:28,259,518...28,282,491
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G |
SFI1 |
SFI1 centrin binding protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SFI1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr22:31,496,139...31,618,588
Ensembl chr22:31,488,688...31,618,588
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G |
SFRP2 |
secreted frizzled related protein 2 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SFRP2 mRNA Methamphetamine results in decreased expression of SFRP2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:153,780,591...153,789,083
Ensembl chr 4:153,780,591...153,789,083
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G |
SGCZ |
sarcoglycan zeta |
affects response to substance |
EXP |
SGCZ gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 8:14,084,845...15,238,431
Ensembl chr 8:14,084,845...15,238,431
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G |
SGK1 |
serum/glucocorticoid regulated kinase 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of SGK1 mRNA Methamphetamine results in increased expression of SGK1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:134,169,256...134,318,112
Ensembl chr 6:134,169,248...134,318,112
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G |
SGK3 |
serum/glucocorticoid regulated kinase family member 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SGK3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 8:66,712,781...66,862,022
Ensembl chr 8:66,712,734...66,862,022
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G |
SGMS1 |
sphingomyelin synthase 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SGMS1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr10:50,305,600...50,625,184
Ensembl chr10:50,305,586...50,625,163
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G |
SH2D3C |
SH2 domain containing 3C |
increases expression |
ISO |
Methamphetamine results in increased expression of SH2D3C mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:127,738,317...127,778,666
Ensembl chr 9:127,738,317...127,778,710
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G |
SH3D19 |
SH3 domain containing 19 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SH3D19 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 4:151,120,281...151,325,605
Ensembl chr 4:151,102,751...151,325,605
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G |
SH3GL1 |
SH3 domain containing GRB2 like 1, endophilin A2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SH3GL1 protein |
CTD |
PMID:19826936 |
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NCBI chr19:4,360,370...4,400,547
Ensembl chr19:4,360,370...4,400,547
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G |
SH3GL2 |
SH3 domain containing GRB2 like 2, endophilin A1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SH3GL2 protein Methamphetamine results in decreased expression of SH3GL2 mRNA |
CTD |
PMID:19826936 PMID:26307267 |
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NCBI chr 9:17,579,066...17,797,124
Ensembl chr 9:17,579,066...17,797,124
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G |
SH3RF3 |
SH3 domain containing ring finger 3 |
affects response to substance |
EXP |
SH3RF3 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 2:109,129,205...109,504,634
Ensembl chr 2:109,129,205...109,504,634
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G |
SH3YL1 |
SH3 and SYLF domain containing 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SH3YL1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:218,136...264,824
Ensembl chr 2:217,730...266,398
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G |
SHCBP1 |
SHC binding and spindle associated 1 |
decreases expression |
EXP ISO |
Methamphetamine results in decreased expression of SHCBP1 mRNA |
CTD |
PMID:25290377 PMID:28341135 |
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NCBI chr16:46,578,591...46,621,379
Ensembl chr16:46,578,591...46,621,379
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G |
SHF |
Src homology 2 domain containing F |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SHF mRNA |
CTD |
PMID:26307267 |
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NCBI chr15:45,167,214...45,201,116
Ensembl chr15:45,167,214...45,201,175
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G |
SHISA2 |
shisa family member 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of SHISA2 mRNA |
CTD |
PMID:28341135 |
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NCBI chr13:26,044,597...26,052,016
Ensembl chr13:26,044,597...26,052,016
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G |
SIAH2 |
siah E3 ubiquitin protein ligase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of SIAH2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:150,741,125...150,763,169
Ensembl chr 3:150,741,125...150,763,477
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G |
SIDT2 |
SID1 transmembrane family member 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of SIDT2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:117,178,743...117,197,442
Ensembl chr11:117,178,736...117,197,445
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G |
SIGIRR |
single Ig and TIR domain containing |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SIGIRR mRNA Methamphetamine results in decreased expression of SIGIRR mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:405,716...417,397
Ensembl chr11:405,716...417,455
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G |
SIK1 |
salt inducible kinase 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of SIK1 mRNA Methamphetamine results in increased expression of SIK1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr21:43,414,483...43,427,131
Ensembl chr21:43,414,483...43,427,131
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G |
SIRT1 |
sirtuin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SIRT1 protein |
CTD |
PMID:35863504 |
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NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390
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G |
SIRT2 |
sirtuin 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SIRT2 mRNA |
CTD |
PMID:25452209 |
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NCBI chr19:38,878,555...38,899,618
Ensembl chr19:38,878,555...38,899,862
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G |
SIRT5 |
sirtuin 5 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SIRT5 mRNA |
CTD |
PMID:25452209 |
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NCBI chr 6:13,574,274...13,615,158
Ensembl chr 6:13,574,227...13,615,158
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G |
SIRT6 |
sirtuin 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SIRT6 mRNA |
CTD |
PMID:25452209 |
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NCBI chr19:4,174,109...4,182,563
Ensembl chr19:4,174,109...4,182,566
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G |
SIRT7 |
sirtuin 7 |
increases expression increases methylation |
ISO |
Methamphetamine results in increased expression of SIRT7 mRNA Methamphetamine results in increased methylation of SIRT7 promoter |
CTD |
PMID:26307267 |
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NCBI chr17:81,911,939...81,918,176
Ensembl chr17:81,911,939...81,921,323
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G |
SIX4 |
SIX homeobox 4 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SIX4 mRNA Methamphetamine results in decreased expression of SIX4 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:60,709,539...60,724,351
Ensembl chr14:60,709,539...60,724,351
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G |
SKA1 |
spindle and kinetochore associated complex subunit 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SKA1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr18:50,375,046...50,394,168
Ensembl chr18:50,375,040...50,394,168
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G |
SLC10A1 |
solute carrier family 10 member 1 |
multiple interactions decreases expression |
ISO |
(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester inhibits the reaction [Methamphetamine results in decreased expression of SLC10A1 mRNA] |
CTD |
PMID:11756511 |
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NCBI chr14:69,775,416...69,797,241
Ensembl chr14:69,775,416...69,797,241
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G |
SLC12A3 |
solute carrier family 12 member 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SLC12A3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:56,865,207...56,915,850
Ensembl chr16:56,865,207...56,915,850
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G |
SLC12A9 |
solute carrier family 12 member 9 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC12A9 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:100,826,869...100,867,012
Ensembl chr 7:100,826,820...100,867,010
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G |
SLC14A2 |
solute carrier family 14 member 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SLC14A2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr18:45,167,963...45,683,688
Ensembl chr18:45,212,995...45,683,688
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G |
SLC16A1 |
solute carrier family 16 member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC16A1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 1:112,911,847...112,956,196
Ensembl chr 1:112,911,847...112,957,593
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G |
SLC16A11 |
solute carrier family 16 member 11 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of SLC16A11 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC16A11 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:7,041,621...7,044,092
Ensembl chr17:7,041,621...7,044,092
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G |
SLC16A13 |
solute carrier family 16 member 13 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of SLC16A13 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC16A13 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:7,036,015...7,040,117
Ensembl chr17:7,036,015...7,040,117
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G |
SLC17A1 |
solute carrier family 17 member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC17A1 mRNA |
CTD |
PMID:15644446 |
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NCBI chr 6:25,723,743...25,832,052
Ensembl chr 6:25,782,915...25,832,052
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G |
SLC18A2 |
solute carrier family 18 member A2 |
decreases expression decreases activity multiple interactions increases nitrosation affects localization decreases response to substance affects response to substance |
EXP ISO |
Methamphetamine results in decreased expression of SLC18A2 protein Methamphetamine results in decreased activity of SLC18A2 protein [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of SLC18A2 protein] S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased activity of SLC18A2 protein]; S-methylthiocitrulline inhibits the reaction [Methamphetamine results in decreased expression of SLC18A2 protein] Methamphetamine results in increased nitrosation of SLC18A2 protein Methamphetamine affects the localization of SLC18A2 protein SLC18A2 protein results in decreased susceptibility to Methamphetamine SLC18A2 protein affects the susceptibility to Methamphetamine |
CTD |
PMID:12050851 PMID:16518646 PMID:16622715 PMID:17683483 PMID:17686046 PMID:18643795 PMID:19326567 PMID:22512859 PMID:33378168 More...
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NCBI chr10:117,241,114...117,279,430
Ensembl chr10:117,241,093...117,279,430
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G |
SLC1A2 |
solute carrier family 1 member 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC1A2 mRNA |
CTD |
PMID:17105907 PMID:18419818 |
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NCBI chr11:35,251,205...35,420,507
Ensembl chr11:35,251,205...35,420,063
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G |
SLC1A3 |
solute carrier family 1 member 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC1A3 mRNA |
CTD |
PMID:18419818 |
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NCBI chr 5:36,606,606...36,688,334
Ensembl chr 5:36,596,588...36,688,334
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G |
SLC22A13 |
solute carrier family 22 member 13 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC22A13 mRNA Methamphetamine results in decreased expression of SLC22A13 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:38,265,812...38,278,757
Ensembl chr 3:38,265,812...38,278,757
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G |
SLC22A3 |
solute carrier family 22 member 3 |
multiple interactions |
ISO |
Methamphetamine inhibits the reaction [SLC22A3 protein results in increased uptake of 1-Methyl-4-phenylpyridinium] |
CTD |
PMID:9830022 |
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NCBI chr 6:160,348,378...160,452,577
Ensembl chr 6:160,348,378...160,452,577
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G |
SLC25A25 |
solute carrier family 25 member 25 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC25A25 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:128,068,232...128,109,245
Ensembl chr 9:128,068,201...128,109,245
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G |
SLC25A28 |
solute carrier family 25 member 28 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC25A28 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:99,610,522...99,659,286
Ensembl chr10:99,610,519...99,622,793
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G |
SLC25A35 |
solute carrier family 25 member 35 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SLC25A35 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:8,287,763...8,295,400
Ensembl chr17:8,287,763...8,295,400
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G |
SLC26A10P |
solute carrier family 26 member 10, pseudogene |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC26A10 mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:57,619,527...57,626,151
Ensembl chr12:57,619,527...57,626,036
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G |
SLC27A1 |
solute carrier family 27 member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC27A1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:17,468,767...17,506,168
Ensembl chr19:17,468,769...17,506,168
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G |
SLC29A3 |
solute carrier family 29 member 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SLC29A3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:71,319,259...71,381,423
Ensembl chr10:71,319,259...71,381,423
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G |
SLC2A12 |
solute carrier family 2 member 12 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SLC2A12 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:133,987,581...134,052,624
Ensembl chr 6:133,987,581...134,052,624
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G |
SLC2A5 |
solute carrier family 2 member 5 |
increases expression |
EXP |
Methamphetamine results in increased expression of SLC2A5 protein |
CTD |
PMID:20110187 |
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NCBI chr 1:9,035,106...9,094,195
Ensembl chr 1:9,035,106...9,088,478
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G |
SLC35B2 |
solute carrier family 35 member B2 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC35B2 mRNA Methamphetamine results in decreased expression of SLC35B2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:44,254,101...44,257,890
Ensembl chr 6:44,254,096...44,257,890
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G |
SLC38A3 |
solute carrier family 38 member 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC38A3 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 3:50,205,271...50,221,486
Ensembl chr 3:50,205,246...50,221,486
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G |
SLC38A5 |
solute carrier family 38 member 5 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC38A5 mRNA Methamphetamine results in decreased expression of SLC38A5 mRNA |
CTD |
PMID:19564919 |
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NCBI chr X:48,458,544...48,470,260
Ensembl chr X:48,458,537...48,470,260
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G |
SLC39A12 |
solute carrier family 39 member 12 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of SLC39A12 mRNA Methamphetamine results in increased expression of SLC39A12 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:17,951,918...18,043,285
Ensembl chr10:17,951,839...18,043,292
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G |
SLC39A3 |
solute carrier family 39 member 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SLC39A3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:2,732,524...2,740,076
Ensembl chr19:2,732,204...2,740,028
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G |
SLC40A1 |
solute carrier family 40 member 1 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of SLC40A1 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC40A1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:189,560,590...189,580,786
Ensembl chr 2:189,560,590...189,583,758
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G |
SLC4A3 |
solute carrier family 4 member 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC4A3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:219,627,630...219,641,971
Ensembl chr 2:219,627,394...219,641,980
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G |
SLC5A3 |
solute carrier family 5 member 3 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of SLC5A3 mRNA Methamphetamine results in increased expression of SLC5A3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr21:34,073,578...34,106,260
Ensembl chr21:34,073,578...34,106,260
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G |
SLC66A1 |
solute carrier family 66 member 1 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of SLC66A1 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC66A1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:19,312,326...19,334,463
Ensembl chr 1:19,312,326...19,329,300
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G |
SLC6A13 |
solute carrier family 6 member 13 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SLC6A13 mRNA Methamphetamine results in decreased expression of SLC6A13 mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:220,622...262,836
Ensembl chr12:220,621...262,873
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G |
SLC6A2 |
solute carrier family 6 member 2 |
multiple interactions |
EXP |
Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein] |
CTD |
PMID:17234900 |
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NCBI chr16:55,655,988...55,706,192
Ensembl chr16:55,655,988...55,707,645
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G |
SLC6A3 |
solute carrier family 6 member 3 |
multiple interactions increases expression decreases activity decreases expression affects response to substance decreases response to substance increases response to substance affects abundance |
EXP ISO |
indatraline inhibits the reaction [SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Methylphenidate inhibits the reaction [SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein] Methamphetamine results in increased expression of SLC6A3 protein Methamphetamine results in decreased activity of SLC6A3 protein Methamphetamine results in decreased expression of SLC6A3 protein SLC6A3 protein affects the susceptibility to Methamphetamine Methamphetamine inhibits the reaction [(1R-(exo,exo))-3-(4-fluorophenyl)-8-methyl-8- azabicyclo(3.2.1)octane-2-carboxylic acid, methyl ester binds to SLC6A3 protein]; Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein] SLC6A3 gene mutant form results in decreased susceptibility to Methamphetamine Methamphetamine results in decreased expression of DAT protein; Methamphetamine results in decreased expression of SLC6A3; Methamphetamine results in decreased expression of SLC6A3 mRNA; Methamphetamine results in decreased expression of SLC6A3 protein 15-deoxyprostaglandin J2 inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; 6,7-dihydroxyflavone inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3]; 7-nitroindazole inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of DAT protein]; ANA 12 compound inhibits the reaction [6,7-dihydroxyflavone inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3]]; Enkephalin, Leucine-2-Alanine inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; estradiol 3-benzoate inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 mRNA]; estradiol 3-benzoate inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; FOS protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Ibuprofen inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; IFNG protein inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; IL6 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; isoliquiritigenin inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein]; Minocycline inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; Naltrexone inhibits the reaction [Enkephalin, Leucine-2-Alanine inhibits the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]]; NOS1 protein affects the reaction [Methamphetamine inhibits the reaction [Mazindol binds to SLC6A3 protein]]; NOS1 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; NR4A2 protein affects the reaction [Methamphetamine results in decreased expression of SLC6A3 protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of DAT protein]; SLC6A3 protein affects the reaction [Methamphetamine affects the abundance of Dopamine]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP mRNA]; SLC6A3 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein] SLC6A3 3' UTR polymorphism results in increased susceptibility to Methamphetamine SLC6A3 protein affects the abundance of Methamphetamine |
CTD |
PMID:9132989 PMID:9634552 PMID:9763484 PMID:9765353 PMID:10559418 PMID:11027249 PMID:11032899 PMID:11085313 PMID:11093760 PMID:11222668 PMID:12050851 PMID:12871582 PMID:12931138 PMID:12944350 PMID:15249736 PMID:15542729 PMID:15900317 PMID:15986185 PMID:16403784 PMID:16518646 PMID:16622715 PMID:16839653 PMID:16842981 PMID:16897726 PMID:17234900 PMID:17992686 PMID:18277051 PMID:18282668 PMID:18946735 PMID:19046384 PMID:19326567 PMID:19648469 PMID:19834288 PMID:20558209 PMID:20575850 PMID:20722968 PMID:21151937 PMID:22329540 PMID:22512859 PMID:23934209 PMID:26283213 PMID:26887589 PMID:29782882 More...
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NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440
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SLC6A4 |
solute carrier family 6 member 4 |
multiple interactions increases response to substance decreases expression affects response to substance affects expression |
EXP ISO |
Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein] SLC6A4 protein results in increased susceptibility to Methamphetamine Methamphetamine results in decreased expression of SLC6A4 protein SLC6A4 mRNA affects the susceptibility to Methamphetamine Methamphetamine affects the expression of SLC6A4 protein IL6 protein affects the reaction [Methamphetamine affects the expression of SLC6A4 protein]; TRP53 protein affects the reaction [Methamphetamine affects the expression of SLC6A4 protein] |
CTD |
PMID:9369336 PMID:10684896 PMID:11093760 PMID:15900317 PMID:16389202 PMID:17234900 PMID:18841348 PMID:19689456 More...
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NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002
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SLC6A8 |
solute carrier family 6 member 8 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC6A8 mRNA |
CTD |
PMID:15644446 |
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NCBI chr X:153,687,926...153,696,593
Ensembl chr X:153,687,926...153,696,588
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G |
SLC6A9 |
solute carrier family 6 member 9 |
increases response to substance |
EXP |
SLC6A9 gene SNP results in increased susceptibility to Methamphetamine |
CTD |
PMID:17582620 |
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NCBI chr 1:43,996,483...44,031,462
Ensembl chr 1:43,991,500...44,031,467
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SLC7A11 |
solute carrier family 7 member 11 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC7A11 mRNA |
CTD |
PMID:28619521 |
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NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349
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SLC7A5 |
solute carrier family 7 member 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC7A5 mRNA |
CTD |
PMID:32035215 |
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NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,023...87,869,507
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SLC9A8 |
solute carrier family 9 member A8 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLC9A8 mRNA |
CTD |
PMID:26307267 |
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NCBI chr20:49,812,828...49,892,242
Ensembl chr20:49,812,713...49,892,242
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G |
SLCO1C1 |
solute carrier organic anion transporter family member 1C1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SLCO1C1 mRNA |
CTD |
PMID:32035215 |
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NCBI chr12:20,695,332...20,753,386
Ensembl chr12:20,695,332...20,753,386
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SLCO2B1 |
solute carrier organic anion transporter family member 2B1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SLCO2B1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:75,151,107...75,206,549
Ensembl chr11:75,100,563...75,206,549
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G |
SLCO4C1 |
solute carrier organic anion transporter family member 4C1 |
increases expression |
EXP |
Methamphetamine results in increased expression of SLCO4C1 mRNA |
CTD |
PMID:25290377 |
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NCBI chr 5:102,233,986...102,296,284
Ensembl chr 5:102,233,986...102,296,284
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G |
SLK |
STE20 like kinase |
increases expression |
ISO |
Methamphetamine results in increased expression of SLK mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:103,967,140...104,029,233
Ensembl chr10:103,967,140...104,029,233
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G |
SMAD3 |
SMAD family member 3 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of SMAD3 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of SMAD3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr15:67,065,602...67,195,169
Ensembl chr15:67,063,763...67,195,173
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G |
SMARCD3 |
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of SMARCD3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:151,238,780...151,277,149
Ensembl chr 7:151,238,764...151,277,896
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G |
SMC3 |
structural maintenance of chromosomes 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of SMC3 mRNA |
CTD |
PMID:15644446 |
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NCBI chr10:110,567,695...110,606,048
Ensembl chr10:110,567,684...110,606,048
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SMCP |
sperm mitochondria associated cysteine rich protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SMCP mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:152,878,322...152,885,047
Ensembl chr 1:152,878,322...152,885,047
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G |
SMOC2 |
SPARC related modular calcium binding 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SMOC2 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 6:168,441,184...168,667,992
Ensembl chr 6:168,441,151...168,673,445
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G |
SMOX |
spermine oxidase |
increases expression |
ISO |
Methamphetamine results in increased expression of SMOX mRNA |
CTD |
PMID:26307267 |
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NCBI chr20:4,148,828...4,187,727
Ensembl chr20:4,120,980...4,187,747
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G |
SMPD4 |
sphingomyelin phosphodiesterase 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of SMPD4 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:130,151,392...130,181,757
Ensembl chr 2:130,151,392...130,182,750
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G |
SMYD3 |
SET and MYND domain containing 3 |
affects response to substance |
EXP |
SMYD3 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 1:245,749,347...246,507,279
Ensembl chr 1:245,749,342...246,507,312
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SNAP29 |
synaptosome associated protein 29 |
increases expression |
ISO |
Methamphetamine results in increased expression of SNAP29 mRNA |
CTD |
PMID:34374793 |
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NCBI chr22:20,859,007...20,891,214
Ensembl chr22:20,859,007...20,891,214
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SNCA |
synuclein alpha |
increases response to substance affects localization multiple interactions increases expression affects response to substance |
EXP ISO |
SNCA gene SNP results in increased susceptibility to Methamphetamine Methamphetamine affects the localization of SNCA protein modified form SNCA protein results in increased susceptibility to Methamphetamine [SNCA protein co-treated with Methamphetamine] results in decreased expression of NR4A2 protein; [SNCA protein co-treated with Methamphetamine] results in increased expression of IL1B protein; [SNCA protein co-treated with Methamphetamine] results in increased expression of IL6 protein; [SNCA protein co-treated with Methamphetamine] results in increased expression of NFKB1 protein; [SNCA protein co-treated with Methamphetamine] results in increased expression of TNF protein; MAPT protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]; Methamphetamine results in increased expression of and results in increased phosphorylation of SNCA protein; SNCA gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of RBFOX3 protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of AIF1 protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of CDK5 protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GFAP protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of GSK3B protein modified form]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MAPT protein modified form]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in increased expression of SNCA protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of CNP protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of MBP protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of TFEB protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of SQSTM1 protein]; SNCA protein affects the reaction [Methamphetamine results in increased phosphorylation of MTOR protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased expression of SNCA protein] PRKN protein inhibits the reaction [Methamphetamine results in increased expression of SNCA protein]; SNCA protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SNCA protein affects the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; SNCA protein affects the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of and results in increased phosphorylation of MAPT protein]; SNCA protein affects the reaction [Methamphetamine results in increased expression of BAX protein]; TRIB3 protein affects the reaction [Methamphetamine results in increased expression of SNCA protein] CEBPB protein affects the reaction [Methamphetamine results in increased expression of SNCA protein]; Methamphetamine promotes the reaction [SNCA protein binds to SNCA protein] SNCA affects the susceptibility to Methamphetamine |
CTD |
PMID:12732244 PMID:15542733 PMID:16181420 PMID:17904249 PMID:25090657 PMID:28661099 PMID:31059759 PMID:31783120 PMID:32278788 PMID:32569805 PMID:34562559 More...
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NCBI chr 4:89,724,099...89,838,304
Ensembl chr 4:89,700,345...89,838,315
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SNCB |
synuclein beta |
increases expression |
ISO |
Methamphetamine results in increased expression of SNCB protein |
CTD |
PMID:19826936 |
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NCBI chr 5:176,620,082...176,630,534
Ensembl chr 5:176,620,082...176,630,556
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G |
SNRK |
SNF related kinase |
increases expression increases methylation |
ISO |
Methamphetamine results in increased expression of SNRK mRNA Methamphetamine results in increased methylation of SNRK promoter |
CTD |
PMID:26307267 |
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NCBI chr 3:43,286,540...43,351,143
Ensembl chr 3:43,286,512...43,424,764
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SNTA1 |
syntrophin alpha 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SNTA1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr20:33,407,957...33,443,763
Ensembl chr20:33,407,957...33,443,763
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G |
SNX27 |
sorting nexin 27 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of SNX27 mRNA alternative form; Methamphetamine results in increased expression of SNX27 protein SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of SNX27 mRNA alternative form] |
CTD |
PMID:12740601 |
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NCBI chr 1:151,612,050...151,699,080
Ensembl chr 1:151,612,006...151,699,091
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G |
SOCS3 |
suppressor of cytokine signaling 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of SOCS3 mRNA |
CTD |
PMID:15644446 |
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NCBI chr17:78,356,778...78,360,925
Ensembl chr17:78,356,778...78,360,077
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G |
SOD1 |
superoxide dismutase 1 |
increases activity multiple interactions affects response to substance affects expression |
EXP ISO |
Methamphetamine results in increased activity of SOD1 protein PRKCD protein affects the reaction [Methamphetamine results in increased activity of SOD1 protein] ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]; PRKCD affects the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased activity of SOD1 protein]]; PRKCD affects the reaction [Methamphetamine results in increased activity of SOD1 protein]; SOD1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein]; SOD1 protein affects the reaction [Methamphetamine results in increased expression of TRP53 protein] SOD1 protein affects the susceptibility to Methamphetamine Methamphetamine affects the expression of SOD1 protein |
CTD |
PMID:7505315 PMID:7530424 PMID:11158245 PMID:11457507 PMID:15189342 PMID:17904249 PMID:24430743 PMID:25523949 More...
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NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931
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G |
SOD2 |
superoxide dismutase 2 |
increases response to substance multiple interactions increases activity |
EXP ISO |
SOD2 gene polymorphism results in increased susceptibility to Methamphetamine PRKCD protein affects the reaction [Methamphetamine results in increased activity of SOD2 protein] PRKCD affects the reaction [Methamphetamine results in increased activity of SOD2 protein] |
CTD |
PMID:16807759 PMID:24430743 PMID:25523949 |
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NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529
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G |
SORBS1 |
sorbin and SH3 domain containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SORBS1 mRNA |
CTD |
PMID:26307267 PMID:36914120 |
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NCBI chr10:95,311,773...95,561,371
Ensembl chr10:95,311,771...95,561,414
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G |
SORCS3 |
sortilin related VPS10 domain containing receptor 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of SORCS3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:104,641,290...105,265,242
Ensembl chr10:104,641,290...105,265,242
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G |
SOX17 |
SRY-box transcription factor 17 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SOX17 mRNA Methamphetamine results in decreased expression of SOX17 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892
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G |
SOX18 |
SRY-box transcription factor 18 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SOX18 mRNA Methamphetamine results in decreased expression of SOX18 mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:64,047,582...64,049,639
Ensembl chr20:64,047,582...64,049,639
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G |
SP100 |
SP100 nuclear antigen |
increases expression |
ISO |
Methamphetamine results in increased expression of SP100 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:230,416,201...230,545,606
Ensembl chr 2:230,415,942...230,545,606
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G |
SPACA9 |
sperm acrosome associated 9 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SPACA9 mRNA Methamphetamine results in decreased expression of SPACA9 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 9:132,878,344...132,890,314
Ensembl chr 9:132,878,027...132,890,201
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G |
SPAG1 |
sperm associated antigen 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SPAG1 mRNA |
CTD |
PMID:35863504 |
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NCBI chr 8:100,158,038...100,241,904
Ensembl chr 8:100,157,906...100,259,278
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G |
SPAG4 |
sperm associated antigen 4 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of SPAG4 promoter |
CTD |
PMID:26307267 |
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NCBI chr20:35,615,829...35,621,094
Ensembl chr20:35,615,829...35,621,094
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G |
SPAG8 |
sperm associated antigen 8 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of SPAG8 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of SPAG8 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:35,807,785...35,812,262
Ensembl chr 9:35,808,045...35,812,272
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G |
SPAG9 |
sperm associated antigen 9 |
increases expression |
ISO |
Methamphetamine results in increased expression of SPAG9 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:50,962,174...51,120,868
Ensembl chr17:50,962,174...51,120,868
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SPARC |
secreted protein acidic and cysteine rich |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SPARC mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 5:151,661,096...151,686,915
Ensembl chr 5:151,661,096...151,686,975
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G |
SPATA6L |
spermatogenesis associated 6 like |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of SPATA6L mRNA Methamphetamine results in decreased expression of SPATA6L mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:4,588,821...4,666,480
Ensembl chr 9:4,553,386...4,666,674
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G |
SPC25 |
SPC25 component of NDC80 kinetochore complex |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SPC25 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 2:168,861,521...168,890,430
Ensembl chr 2:168,834,132...168,913,371
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SPEG |
striated muscle enriched protein kinase |
increases expression |
ISO |
Methamphetamine results in increased expression of SPEG mRNA |
CTD |
PMID:26307267 PMID:36914120 |
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NCBI chr 2:219,434,843...219,493,629
Ensembl chr 2:219,434,843...219,493,629
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G |
SPMIP11 |
sperm microtubule inner protein 11 |
increases expression |
ISO |
Methamphetamine results in increased expression of SPMIP11 mRNA |
CTD |
PMID:28341135 |
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NCBI chr12:48,727,435...48,771,459
Ensembl chr12:48,727,435...48,765,790
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G |
SPOCK2 |
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of SPOCK2 mRNA |
CTD |
PMID:32035215 |
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NCBI chr10:72,059,034...72,089,032
Ensembl chr10:72,059,034...72,089,032
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G |
SPRED1 |
sprouty related EVH1 domain containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SPRED1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr15:38,252,836...38,357,249
Ensembl chr15:38,252,836...38,357,249
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G |
SPTAN1 |
spectrin alpha, non-erythrocytic 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SPTAN1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:128,552,587...128,633,662
Ensembl chr 9:128,552,558...128,633,662
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G |
SPTY2D1 |
SPT2 chromatin protein domain containing 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SPTY2D1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:18,606,403...18,634,342
Ensembl chr11:18,606,403...18,634,791
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SQSTM1 |
sequestosome 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of SQSTM1 protein SNCA protein affects the reaction [Methamphetamine results in increased expression of SQSTM1 protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased expression of SQSTM1 protein] Lactulose promotes the reaction [Methamphetamine results in increased expression of SQSTM1 mRNA]; STX17 protein inhibits the reaction [Methamphetamine results in increased expression of SQSTM1 protein] Methamphetamine results in increased expression of SQSTM1 mRNA; Methamphetamine results in increased expression of SQSTM1 protein |
CTD |
PMID:23933405 PMID:30450033 PMID:34374793 PMID:34562559 |
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NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078
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G |
SRF |
serum response factor |
increases expression |
ISO |
Methamphetamine results in increased expression of SRF mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 6:43,171,269...43,181,506
Ensembl chr 6:43,171,269...43,181,506
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G |
SRGAP1 |
SLIT-ROBO Rho GTPase activating protein 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SRGAP1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:63,844,700...64,162,217
Ensembl chr12:63,843,761...64,162,217
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G |
SRGAP2 |
SLIT-ROBO Rho GTPase activating protein 2 |
increases methylation increases expression |
ISO |
Methamphetamine results in increased methylation of SRGAP2 promoter Methamphetamine results in increased expression of SRGAP2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:206,203,541...206,464,436
Ensembl chr 1:206,203,346...206,464,436
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G |
SRPK3 |
SRSF protein kinase 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of SRPK3 mRNA |
CTD |
PMID:26307267 |
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NCBI chr X:153,781,041...153,785,730
Ensembl chr X:153,776,412...153,785,732
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G |
SRPX |
sushi repeat containing protein X-linked |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SRPX mRNA |
CTD |
PMID:15644446 |
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NCBI chr X:38,149,339...38,220,871
Ensembl chr X:38,149,336...38,220,924
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G |
SRRM1 |
serine and arginine repetitive matrix 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SRRM1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:24,643,302...24,673,281
Ensembl chr 1:24,631,716...24,673,281
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SRRM2 |
serine/arginine repetitive matrix 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of SRRM2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:2,752,638...2,771,412
Ensembl chr16:2,752,626...2,772,538
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SRRT |
serrate, RNA effector molecule |
increases expression decreases methylation |
ISO |
Methamphetamine results in increased expression of SRRT mRNA Methamphetamine results in decreased methylation of SRRT promoter |
CTD |
PMID:26307267 |
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NCBI chr 7:100,875,103...100,888,664
Ensembl chr 7:100,875,103...100,888,664
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G |
SRSF5 |
serine and arginine rich splicing factor 5 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SRSF5 mRNA |
CTD |
PMID:36914120 |
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NCBI chr14:69,767,142...69,772,005
Ensembl chr14:69,726,900...69,772,005
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G |
SSTR2 |
somatostatin receptor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of SSTR2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:73,165,010...73,176,633
Ensembl chr17:73,165,010...73,176,633
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G |
ST13 |
ST13 Hsp70 interacting protein |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of ST13 mRNA SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of ST13 mRNA] |
CTD |
PMID:19149911 PMID:19564919 |
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NCBI chr22:40,824,535...40,856,639
Ensembl chr22:40,824,535...40,856,639
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G |
ST3GAL1 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ST3GAL1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 8:133,454,848...133,571,887
Ensembl chr 8:133,454,848...133,571,926
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G |
ST3GAL5 |
ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of ST3GAL5 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 2:85,837,120...85,889,034
Ensembl chr 2:85,837,120...85,905,199
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G |
ST8SIA6 |
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ST8SIA6 mRNA Methamphetamine results in decreased expression of ST8SIA6 mRNA |
CTD |
PMID:19564919 |
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NCBI chr10:17,315,421...17,454,595
Ensembl chr10:17,315,421...17,454,595
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G |
STAT6 |
signal transducer and activator of transcription 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of STAT6 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr12:57,095,408...57,111,362
Ensembl chr12:57,095,408...57,132,139
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G |
STC2 |
stanniocalcin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of STC2 mRNA |
CTD |
PMID:28619521 |
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NCBI chr 5:173,314,723...173,328,414
Ensembl chr 5:173,314,723...173,328,447
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G |
STEAP1 |
STEAP family member 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of STEAP1 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of STEAP1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:90,154,469...90,164,827
Ensembl chr 7:90,154,456...90,164,829
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G |
STIM1 |
stromal interaction molecule 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of STIM1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210
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G |
STIP1 |
stress induced phosphoprotein 1 |
decreases expression increases expression |
ISO |
Methamphetamine results in decreased expression of STIP1 protein Methamphetamine results in increased expression of STIP1 mRNA |
CTD |
PMID:19149911 PMID:19564919 PMID:19826936 |
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NCBI chr11:64,185,272...64,204,543
Ensembl chr11:64,185,272...64,204,543
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G |
STK11IP |
serine/threonine kinase 11 interacting protein |
increases expression |
ISO |
Methamphetamine results in increased expression of STK11IP mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 2:219,597,857...219,616,451
Ensembl chr 2:219,597,857...219,616,451
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G |
STMN1 |
stathmin 1 |
affects expression |
ISO |
Methamphetamine affects the expression of STMN1 protein |
CTD |
PMID:17904249 |
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NCBI chr 1:25,884,179...25,906,880
Ensembl chr 1:25,884,181...25,906,991
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G |
STPG1 |
sperm tail PG-rich repeat containing 1 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of STPG1 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 1:24,356,999...24,415,044
Ensembl chr 1:24,356,999...24,416,934
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G |
STRA6 |
signaling receptor and transporter of retinol STRA6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of STRA6 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr15:74,179,466...74,212,259
Ensembl chr15:74,179,466...74,212,267
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G |
STRADA |
STE20 related adaptor alpha |
decreases expression |
ISO |
Methamphetamine results in decreased expression of STRADA mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:63,702,832...63,741,986
Ensembl chr17:63,682,336...63,741,986
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G |
STX17 |
syntaxin 17 |
multiple interactions decreases expression |
ISO |
STX17 protein inhibits the reaction [Methamphetamine results in decreased expression of BCL2 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased cleavage of CASP3 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased expression of SQSTM1 protein]; STX17 protein inhibits the reaction [Methamphetamine results in increased lipidation of MAP1LC3B protein] Methamphetamine results in decreased expression of STX17 mRNA; Methamphetamine results in decreased expression of STX17 protein |
CTD |
PMID:34374793 PMID:35643125 |
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NCBI chr 9:99,906,654...99,974,534
Ensembl chr 9:99,906,654...99,974,534
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G |
STYXL1 |
serine/threonine/tyrosine interacting like 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of STYXL1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:75,996,337...76,048,000
Ensembl chr 7:75,996,338...76,048,004
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G |
SULT1A1 |
sulfotransferase family 1A member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SULT1A1 mRNA; Methamphetamine results in increased expression of SULT1A1 protein |
CTD |
PMID:23026138 |
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NCBI chr16:28,605,258...28,623,375
Ensembl chr16:28,605,196...28,610,044
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G |
SULT2A1 |
sulfotransferase family 2A member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SULT2A1 mRNA; Methamphetamine results in increased expression of SULT2A1 protein |
CTD |
PMID:23026138 |
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NCBI chr19:47,870,467...47,886,315
Ensembl chr19:47,870,467...47,886,315
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G |
SUPT5H |
SPT5 homolog, DSIF elongation factor subunit |
increases expression |
ISO |
Methamphetamine results in increased expression of SUPT5H mRNA |
CTD |
PMID:26307267 |
|
NCBI chr19:39,445,582...39,476,670
Ensembl chr19:39,436,156...39,476,670
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G |
SUPT6H |
SPT6 homolog, histone chaperone and transcription elongation factor |
increases expression |
ISO |
Methamphetamine results in increased expression of SUPT6H mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:28,662,205...28,702,679
Ensembl chr17:28,662,198...28,702,679
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G |
SV2C |
synaptic vesicle glycoprotein 2C |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of SV2C mRNA Methamphetamine results in increased expression of SV2C mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 5:75,847,464...76,353,939
Ensembl chr 5:76,083,383...76,353,939
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G |
SVIL |
supervillin |
increases expression |
ISO |
Methamphetamine results in increased expression of SVIL mRNA |
CTD |
PMID:26307267 |
|
NCBI chr10:29,457,338...29,736,936
Ensembl chr10:29,457,338...29,736,959
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G |
SWT1 |
SWT1 RNA endoribonuclease homolog |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of SWT1 mRNA Methamphetamine results in increased expression of SWT1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:185,157,060...185,291,781
Ensembl chr 1:185,157,080...185,291,781
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G |
SYN1 |
synapsin I |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SYN1 protein |
CTD |
PMID:34461196 |
|
NCBI chr X:47,571,901...47,619,857
Ensembl chr X:47,571,901...47,619,857
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G |
SYN2 |
synapsin II |
increases expression |
ISO |
Methamphetamine results in increased expression of SYN2 protein |
CTD |
PMID:19826936 |
|
NCBI chr 3:12,004,388...12,192,032
Ensembl chr 3:12,004,388...12,192,032
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G |
SYNE1 |
spectrin repeat containing nuclear envelope protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of SYNE1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 6:152,121,687...152,637,362
Ensembl chr 6:152,121,687...152,637,801
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G |
SYNJ2 |
synaptojanin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of SYNJ2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 6:157,981,296...158,099,176
Ensembl chr 6:157,981,863...158,099,176
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G |
SYP |
synaptophysin |
decreases expression increases expression multiple interactions |
ISO EXP |
Methamphetamine results in decreased expression of SYP protein Methamphetamine results in increased expression of SYP protein 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione inhibits the reaction [Methamphetamine results in increased expression of SYP protein]; Melatonin inhibits the reaction [Methamphetamine results in decreased expression of SYP protein] |
CTD |
PMID:14657756 PMID:19409439 PMID:33421459 |
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NCBI chr X:49,187,815...49,200,193
Ensembl chr X:49,187,815...49,200,218
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G |
SYT10 |
synaptotagmin 10 |
decreases expression increases expression |
ISO |
Methamphetamine results in decreased expression of SYT10 mRNA Methamphetamine results in increased expression of SYT10 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr12:33,374,238...33,439,819
Ensembl chr12:33,374,238...33,439,819
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G |
SYT17 |
synaptotagmin 17 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of SYT17 promoter |
CTD |
PMID:26307267 |
|
NCBI chr16:19,167,834...19,268,332
Ensembl chr16:19,167,971...19,268,332
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G |
SYT2 |
synaptotagmin 2 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] affects the expression of SYT2 mRNA Methamphetamine results in decreased expression of SYT2 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:202,590,596...202,710,454
Ensembl chr 1:202,590,596...202,710,454
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G |
SYT3 |
synaptotagmin 3 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SYT3 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr19:50,621,977...50,658,105
Ensembl chr19:50,621,307...50,639,881
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G |
SYT9 |
synaptotagmin 9 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of SYT9 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:7,238,778...7,469,043
Ensembl chr11:7,238,778...7,469,043
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G |
TAAR1 |
trace amine associated receptor 1 |
multiple interactions affects response to substance |
EXP ISO |
Citalopram inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Desipramine inhibits the reaction [SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; indatraline inhibits the reaction [SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; Methylphenidate inhibits the reaction [SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]]; SLC6A2 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]; SLC6A3 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein]; SLC6A4 protein promotes the reaction [Methamphetamine results in increased activity of TAAR1 protein] TAAR1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; TAAR1 protein affects the reaction [Methamphetamine results in increased expression of GFAP protein] TAAR1 protein affects the susceptibility to Methamphetamine |
CTD |
PMID:17234900 PMID:28919515 |
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NCBI chr 6:132,643,312...132,659,182
Ensembl chr 6:132,643,312...132,659,182
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G |
TAC1 |
tachykinin precursor 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of TAC1 mRNA Methamphetamine results in increased expression of TAC1 mRNA; Methamphetamine results in increased expression of TAC1 protein modified form ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 mRNA]; ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 protein modified form]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 mRNA]]; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [Methamphetamine results in increased expression of TAC1 protein modified form]]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of TAC1 mRNA]; PDYN gene mutant form promotes the reaction [Methamphetamine results in increased expression of TAC1 protein modified form] |
CTD |
PMID:15644446 PMID:29467000 |
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NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
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G |
TACC2 |
transforming acidic coiled-coil containing protein 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of TACC2 mRNA |
CTD |
PMID:26307267 PMID:36914120 |
|
NCBI chr10:121,989,163...122,254,542
Ensembl chr10:121,989,163...122,254,545
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G |
TADA1 |
transcriptional adaptor 1 |
increases methylation |
ISO |
Methamphetamine results in increased methylation of TADA1 promoter |
CTD |
PMID:26307267 |
|
NCBI chr 1:166,856,510...166,876,264
Ensembl chr 1:166,856,510...166,876,264
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G |
TAF15 |
TATA-box binding protein associated factor 15 |
increases expression |
ISO |
Methamphetamine results in increased expression of TAF15 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:35,809,484...35,847,242
Ensembl chr17:35,809,482...35,864,615
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G |
TAF1C |
TATA-box binding protein associated factor, RNA polymerase I subunit C |
affects methylation increases expression |
ISO |
Methamphetamine affects the methylation of TAF1C promoter Methamphetamine results in increased expression of TAF1C mRNA |
CTD |
PMID:26307267 |
|
NCBI chr16:84,177,855...84,187,057
Ensembl chr16:84,177,847...84,187,070
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G |
TAFA5 |
TAFA chemokine like family member 5 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TAFA5 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr22:48,489,553...48,751,932
Ensembl chr22:48,489,553...48,850,912
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G |
TAGLN3 |
transgelin 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of TAGLN3 protein |
CTD |
PMID:19826936 |
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NCBI chr 3:111,998,922...112,013,885
Ensembl chr 3:111,998,739...112,013,887
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G |
TAOK2 |
TAO kinase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of TAOK2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr16:29,973,868...29,992,261
Ensembl chr16:29,973,868...29,992,261
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G |
TARBP2 |
TARBP2 subunit of RISC loading complex |
increases expression |
ISO |
Methamphetamine results in increased expression of TARBP2 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr12:53,500,923...53,506,431
Ensembl chr12:53,500,921...53,506,431
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G |
TAS1R1 |
taste 1 receptor member 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TAS1R1 mRNA Methamphetamine results in decreased expression of TAS1R1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 1:6,555,307...6,579,755
Ensembl chr 1:6,555,307...6,579,755
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G |
TAS2R1 |
taste 2 receptor member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TAS2R119 mRNA |
CTD |
PMID:15644446 |
|
NCBI chr 5:9,627,347...9,903,876
Ensembl chr 5:9,627,347...9,712,378
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G |
TBC1D4 |
TBC1 domain family member 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of TBC1D4 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr13:75,283,503...75,482,169
Ensembl chr13:75,283,503...75,482,169
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G |
TCAP |
titin-cap |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TCAP mRNA |
CTD |
PMID:36914120 |
|
NCBI chr17:39,665,349...39,666,554
Ensembl chr17:39,665,349...39,666,554
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G |
TCF15 |
transcription factor 15 |
increases expression |
ISO |
Methamphetamine results in increased expression of TCF15 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr20:604,257...610,309
Ensembl chr20:604,257...610,309
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G |
TCF4 |
transcription factor 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of TCF4 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr18:55,222,185...55,635,957
Ensembl chr18:55,222,185...55,664,787
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G |
TDH |
L-threonine dehydrogenase (pseudogene) |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TDH mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:11,339,637...11,368,452
Ensembl chr 8:11,339,637...11,368,452 Ensembl chr 8:11,339,637...11,368,452
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G |
TDRP |
testis development related protein |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TDRP mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:489,946...545,780
Ensembl chr 8:489,803...545,781
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G |
TECPR1 |
tectonin beta-propeller repeat containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TECPR1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 7:98,214,624...98,252,232
Ensembl chr 7:98,214,624...98,252,232
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G |
TECRL |
trans-2,3-enoyl-CoA reductase like |
increases expression |
ISO |
Methamphetamine results in increased expression of TECRL mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 4:64,276,298...64,409,460
Ensembl chr 4:64,275,257...64,409,468
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G |
TECTA |
tectorin alpha |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TECTA mRNA Methamphetamine results in decreased expression of TECTA mRNA |
CTD |
PMID:19564919 |
|
NCBI chr11:121,101,243...121,191,490
Ensembl chr11:121,101,243...121,191,490
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G |
TEF |
TEF transcription factor, PAR bZIP family member |
increases expression |
ISO |
Methamphetamine results in increased expression of TEF mRNA |
CTD |
PMID:26307267 |
|
NCBI chr22:41,367,455...41,399,326
Ensembl chr22:41,367,333...41,399,326
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G |
TEKT1 |
tektin 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TEKT1 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:6,797,993...6,831,729
Ensembl chr17:6,789,133...6,831,761
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G |
TENT5A |
terminal nucleotidyltransferase 5A |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of TENT5A mRNA Methamphetamine results in increased expression of TENT5A mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 6:81,745,730...81,752,681
Ensembl chr 6:81,491,439...81,752,774
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G |
TERF1 |
telomeric repeat binding factor 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TERF1 mRNA Methamphetamine results in decreased expression of TERF1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 8:73,008,864...73,048,123
Ensembl chr 8:73,008,856...73,048,123
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G |
TEX13B |
testis expressed 13B |
increases expression |
ISO |
Methamphetamine results in increased expression of TEX13B mRNA |
CTD |
PMID:28341135 |
|
NCBI chr X:107,980,864...107,982,370
Ensembl chr X:107,980,864...107,982,370
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G |
TEX28 |
testis expressed 28 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TEX28 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr X:154,271,265...154,295,211
Ensembl chr X:154,271,265...154,295,853
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G |
TFAP2A |
transcription factor AP-2 alpha |
increases expression |
ISO |
Methamphetamine results in increased expression of TFAP2A mRNA |
CTD |
PMID:28341135 |
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NCBI chr 6:10,396,677...10,419,659
Ensembl chr 6:10,393,186...10,419,659
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G |
TFEB |
transcription factor EB |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of TFEB protein SNCA protein affects the reaction [Methamphetamine results in decreased expression of TFEB protein]; TFEB protein inhibits the reaction [Methamphetamine results in decreased expression of CNP protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased expression of SNCA protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased expression of SQSTM1 protein]; TFEB protein inhibits the reaction [Methamphetamine results in increased phosphorylation of MTOR protein] |
CTD |
PMID:34562559 |
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NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259
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G |
TGFB1 |
transforming growth factor beta 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TGFB1 mRNA Methamphetamine results in increased expression of TGFB1 protein |
CTD |
PMID:12766323 PMID:35863504 |
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NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922
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G |
TGFB2 |
transforming growth factor beta 2 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of TGFB2 mRNA GATA4 protein affects the reaction [Methamphetamine results in increased expression of TGFB2 mRNA] |
CTD |
PMID:36914120 |
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NCBI chr 1:218,345,336...218,444,619
Ensembl chr 1:218,345,336...218,444,619
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G |
TGFBR1 |
transforming growth factor beta receptor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TGFBR1 mRNA |
CTD |
PMID:12766323 |
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NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192
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G |
TGFBR2 |
transforming growth factor beta receptor 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of TGFBR2 mRNA |
CTD |
PMID:12766323 PMID:15644446 |
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NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,601...30,694,142
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G |
TH |
tyrosine hydroxylase |
decreases expression multiple interactions decreases activity affects expression affects response to substance |
EXP ISO |
Methamphetamine results in decreased expression of TH protein ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; Methamphetamine results in decreased expression of and results in decreased activity of TH protein; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein] Methamphetamine results in decreased expression of TH mRNA; Methamphetamine results in decreased expression of TH protein Methamphetamine results in decreased activity of TH protein Methamphetamine affects the expression of TH mRNA diadenosine tetraphosphate inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; Lithium inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; Melatonin inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; olanzapine inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; Valproic Acid inhibits the reaction [Methamphetamine results in decreased expression of TH protein] TH protein affects the susceptibility to Methamphetamine 3-((3,5-bis(trifluoromethyl)phenyl)methyloxy)-2-phenylpiperidine inhibits the reaction [norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]]; 7-nitroindazole affects the reaction [Methamphetamine results in decreased expression of TH protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased activity of TH protein]; [rottlerin results in decreased activity of PRKCD protein] inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; [TH protein affects the abundance of Dopamine] which affects the susceptibility to Methamphetamine; [TH protein affects the chemical synthesis of Dopamine] which affects the susceptibility to Methamphetamine; Caffeine promotes the reaction [Methamphetamine results in decreased activity of TH protein]; Chlormethiazole inhibits the reaction [Methamphetamine results in decreased activity of TH protein]; EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; ginsenoside Re inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]; GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; Methamphetamine results in decreased expression of and results in decreased activity of TH protein; Methamphetamine results in decreased expression of and results in increased phosphorylation of TH protein; norbinaltorphimine inhibits the reaction [ginsenoside Re inhibits the reaction [PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]]]; NR4A2 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; OPRM1 protein affects the susceptibility to [Methamphetamine results in decreased expression of TH mRNA]; OPRM1 protein affects the susceptibility to [Methamphetamine results in decreased expression of TH protein]; PDYN gene mutant form promotes the reaction [Methamphetamine results in decreased expression of TH protein]; Phencyclidine inhibits the reaction [Methamphetamine results in decreased activity of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased activity of TH protein]; PRKCD protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; pyrrolidine dithiocarbamic acid affects the reaction [GPX1 protein affects the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]]; pyrrolidine dithiocarbamic acid inhibits the reaction [Methamphetamine results in decreased expression of and results in decreased activity of TH protein]; Raclopride inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; SCH 23390 inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; SNCA gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TH protein]; TAAR1 protein affects the reaction [Methamphetamine results in decreased expression of TH protein]; talipexole inhibits the reaction [Methamphetamine results in decreased activity of TH protein] |
CTD |
PMID:1381816 PMID:2579200 PMID:7996441 PMID:8931477 PMID:9655613 PMID:9739098 PMID:9765353 PMID:9822156 PMID:10773198 PMID:10984662 PMID:12871582 PMID:15276877 PMID:16088948 PMID:16622715 PMID:18277051 PMID:19149911 PMID:19409439 PMID:19442829 PMID:20722968 PMID:21151937 PMID:21867746 PMID:22329540 PMID:22512859 PMID:24042092 PMID:24072398 PMID:25523949 PMID:26283213 PMID:28661099 PMID:28919515 PMID:29467000 PMID:29782882 PMID:31422080 PMID:32278788 PMID:32768653 PMID:33359793 PMID:34082047 More...
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NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815
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G |
THADA |
THADA armadillo repeat containing |
decreases expression |
ISO |
Methamphetamine results in decreased expression of THADA mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:43,230,851...43,596,038
Ensembl chr 2:43,230,851...43,596,038
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G |
THBS3 |
thrombospondin 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of THBS3 mRNA |
CTD |
PMID:35863504 |
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NCBI chr 1:155,195,588...155,209,178
Ensembl chr 1:155,195,588...155,209,051
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G |
THPO |
thrombopoietin |
increases expression |
EXP |
Methamphetamine results in increased expression of THPO mRNA |
CTD |
PMID:25290377 |
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NCBI chr 3:184,371,935...184,379,688
Ensembl chr 3:184,371,935...184,381,968
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G |
THRA |
thyroid hormone receptor alpha |
decreases expression |
ISO |
Methamphetamine results in decreased expression of THRA mRNA |
CTD |
PMID:35301009 |
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NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867
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G |
THSD1 |
thrombospondin type 1 domain containing 1 |
increases expression decreases expression |
ISO |
Methamphetamine results in increased expression of THSD1 mRNA Methamphetamine results in decreased expression of THSD1 mRNA |
CTD |
PMID:19564919 PMID:26307267 |
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NCBI chr13:52,377,167...52,406,172
Ensembl chr13:52,377,167...52,416,373
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G |
TICAM1 |
TIR domain containing adaptor molecule 1 |
multiple interactions increases expression |
ISO |
TICAM1 protein promotes the reaction [Methamphetamine results in increased expression of IL1B protein]; TICAM1 protein promotes the reaction [Methamphetamine results in increased expression of IL6 protein] Methamphetamine results in increased expression of TICAM1 protein |
CTD |
PMID:32768653 |
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NCBI chr19:4,815,932...4,831,712
Ensembl chr19:4,815,932...4,831,712
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G |
TIE1 |
tyrosine kinase with immunoglobulin like and EGF like domains 1 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TIE1 mRNA Methamphetamine results in decreased expression of TIE1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:43,300,982...43,323,108
Ensembl chr 1:43,300,982...43,323,108
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G |
TIGAR |
TP53 induced glycolysis regulatory phosphatase |
increases expression |
ISO |
Methamphetamine results in increased expression of TIGAR mRNA |
CTD |
PMID:36914120 |
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NCBI chr12:4,321,213...4,360,028
Ensembl chr12:4,307,763...4,360,028
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G |
TIMM17B |
translocase of inner mitochondrial membrane 17B |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TIMM17B mRNA |
CTD |
PMID:19149911 |
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NCBI chr X:48,893,447...48,898,143
Ensembl chr X:48,893,447...48,898,143
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G |
TIMP1 |
TIMP metallopeptidase inhibitor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TIMP1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789
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G |
TIMP2 |
TIMP metallopeptidase inhibitor 2 |
decreases response to substance increases activity |
ISO |
TIMP2 protein results in decreased susceptibility to Methamphetamine Methamphetamine results in increased activity of TIMP2 protein |
CTD |
PMID:18198472 |
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NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387
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G |
TIMP4 |
TIMP metallopeptidase inhibitor 4 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TIMP4 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 3:12,153,068...12,158,912
Ensembl chr 3:12,153,068...12,158,912
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G |
TJAP1 |
tight junction associated protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TJAP1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 6:43,477,570...43,506,554
Ensembl chr 6:43,477,523...43,506,556
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G |
TJP1 |
tight junction protein 1 |
multiple interactions decreases expression |
ISO |
[Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of TJP1 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in decreased expression of TJP1 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TJP1 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TJP1 protein] Methamphetamine results in decreased expression of TJP1 mRNA; Methamphetamine results in decreased expression of TJP1 protein |
CTD |
PMID:35390362 |
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NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915
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G |
TK2 |
thymidine kinase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of TK2 mRNA |
CTD |
PMID:19149911 |
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NCBI chr16:66,508,003...66,550,291
Ensembl chr16:66,508,003...66,552,544
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G |
TLCD3B |
TLC domain containing 3B |
increases expression |
ISO |
Methamphetamine results in increased expression of TLCD3B mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:30,024,427...30,053,040
Ensembl chr16:30,024,427...30,052,978
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G |
TLE2 |
TLE family member 2, transcriptional corepressor |
increases expression |
ISO |
Methamphetamine results in increased expression of TLE2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:2,997,644...3,047,635
Ensembl chr19:2,997,639...3,047,635
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G |
TLE3 |
TLE family member 3, transcriptional corepressor |
increases expression |
ISO |
Methamphetamine results in increased expression of TLE3 mRNA |
CTD |
PMID:15644446 PMID:26307267 |
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NCBI chr15:70,047,790...70,097,917
Ensembl chr15:70,047,790...70,098,176
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G |
TLR1 |
toll like receptor 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TLR1 mRNA |
CTD |
PMID:32768653 |
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NCBI chr 4:38,787,569...38,805,644
Ensembl chr 4:38,790,677...38,856,817
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G |
TLR2 |
toll like receptor 2 |
multiple interactions increases expression decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TLR2 mRNA Methamphetamine results in increased expression of TLR2 mRNA Methamphetamine results in decreased expression of TLR2 mRNA |
CTD |
PMID:19564919 PMID:32768653 |
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NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,070...153,706,260
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G |
TLR3 |
toll like receptor 3 |
increases expression |
ISO |
Methamphetamine results in increased expression of TLR3 mRNA |
CTD |
PMID:32768653 |
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NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073
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G |
TLR4 |
toll like receptor 4 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of TLR4 protein [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TLR4 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TLR4 protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of TLR4 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of CLDN5 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of OCLN protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TJP1 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in decreased expression of TJP1 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of IL1B mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of IL1B protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MYD88 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of MYD88 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of RELA mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of RELA protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TNF protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TRAF6 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TRAF6 protein] Methamphetamine results in increased expression of TLR4 mRNA; Methamphetamine results in increased expression of TLR4 protein Lactulose inhibits the reaction [Methamphetamine results in increased expression of TLR4 protein] |
CTD |
PMID:30450033 PMID:32768653 PMID:33359793 PMID:35390362 PMID:35688268 PMID:36720452 More...
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NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735
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G |
TLR5 |
toll like receptor 5 |
increases expression |
ISO |
Methamphetamine results in increased expression of TLR5 mRNA |
CTD |
PMID:32768653 |
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NCBI chr 1:223,109,404...223,143,248
Ensembl chr 1:223,109,404...223,143,248
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G |
TLR6 |
toll like receptor 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of TLR6 mRNA |
CTD |
PMID:32768653 |
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NCBI chr 4:38,822,897...38,868,390
Ensembl chr 4:38,822,897...38,856,817
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G |
TLR7 |
toll like receptor 7 |
increases expression |
ISO |
Methamphetamine results in increased expression of TLR7 mRNA |
CTD |
PMID:32768653 |
|
NCBI chr X:12,867,072...12,890,361
Ensembl chr X:12,867,072...12,890,361
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G |
TLR8 |
toll like receptor 8 |
increases expression |
ISO |
Methamphetamine results in increased expression of TLR8 mRNA |
CTD |
PMID:32768653 |
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NCBI chr X:12,906,620...12,923,169
Ensembl chr X:12,906,620...12,923,169
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G |
TLR9 |
toll like receptor 9 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TLR9 mRNA |
CTD |
PMID:32768653 |
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NCBI chr 3:52,221,080...52,225,645
Ensembl chr 3:52,221,080...52,225,645
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G |
TMC6 |
transmembrane channel like 6 |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of TMC6 promoter Methamphetamine results in increased expression of TMC6 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:78,107,397...78,132,427
Ensembl chr17:78,107,397...78,132,407
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G |
TMEM123 |
transmembrane protein 123 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM123 mRNA Methamphetamine results in decreased expression of TMEM123 mRNA |
CTD |
PMID:19564919 |
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NCBI chr11:102,396,332...102,452,765
Ensembl chr11:102,396,332...102,470,384
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G |
TMEM125 |
transmembrane protein 125 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of TMEM125 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM125 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:43,269,983...43,274,002
Ensembl chr 1:43,269,983...43,274,002
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G |
TMEM150A |
transmembrane protein 150A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TMEM150A mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:85,598,547...85,602,698
Ensembl chr 2:85,598,547...85,603,196
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G |
TMEM154 |
transmembrane protein 154 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TMEM154 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 4:152,618,628...152,679,997
Ensembl chr 4:152,618,628...152,680,012
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G |
TMEM177 |
transmembrane protein 177 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TMEM177 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:119,679,201...119,723,618
Ensembl chr 2:119,679,167...119,686,507
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G |
TMEM18 |
transmembrane protein 18 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of TMEM18 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMEM18 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:663,877...677,406
Ensembl chr 2:663,877...677,406
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G |
TMEM252 |
transmembrane protein 252 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of TMEM252 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of TMEM252 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:68,536,580...68,540,883
Ensembl chr 9:68,536,580...68,540,883
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G |
TMEM255B |
transmembrane protein 255B |
increases expression |
ISO |
Methamphetamine results in increased expression of TMEM255B mRNA |
CTD |
PMID:26307267 |
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NCBI chr13:113,759,226...113,816,995
Ensembl chr13:113,759,226...113,816,995
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G |
TMEM259 |
transmembrane protein 259 |
increases expression |
ISO |
Methamphetamine results in increased expression of TMEM259 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:1,009,653...1,021,123
Ensembl chr19:1,009,648...1,021,179
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G |
TMEM63A |
transmembrane protein 63A |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TMEM63A mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:225,840,556...225,882,380
Ensembl chr 1:225,845,536...225,882,380
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G |
TMEM91 |
transmembrane protein 91 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TMEM91 mRNA |
CTD |
PMID:32035215 |
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NCBI chr19:41,363,947...41,384,083
Ensembl chr19:41,350,911...41,384,083
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G |
TMEM94 |
transmembrane protein 94 |
increases expression |
ISO |
Methamphetamine results in increased expression of TMEM94 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:75,456,635...75,500,452
Ensembl chr17:75,441,159...75,500,452
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G |
TMSB10 |
thymosin beta 10 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TMSB10 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 2:84,905,656...84,906,671
Ensembl chr 2:84,905,656...84,906,671
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G |
TMTC3 |
transmembrane O-mannosyltransferase targeting cadherins 3 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of TMTC3 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of TMTC3 mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:88,142,307...88,199,887
Ensembl chr12:88,142,296...88,199,887
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G |
TMX1 |
thioredoxin related transmembrane protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TMX1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:51,240,247...51,257,655
Ensembl chr14:51,240,162...51,257,655
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G |
TNF |
tumor necrosis factor |
multiple interactions increases expression increases secretion increases response to substance affects response to substance |
EXP ISO |
luzindole inhibits the reaction [Melatonin inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; MTNR1B protein promotes the reaction [Melatonin inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]]; TNF protein inhibits the reaction [Methamphetamine results in decreased uptake of Dopamine]; TNF protein inhibits the reaction [Methamphetamine results in increased secretion of Dopamine] [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of and results in increased secretion of TNF protein]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; [SNCA protein co-treated with Methamphetamine] results in increased expression of TNF protein; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased expression of TNF protein]; CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]; Devazepide promotes the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]; L 365260 inhibits the reaction [CCK protein alternative form inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]]; Methamphetamine results in increased expression of and results in increased secretion of TNF protein; Minocycline inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]; obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; PELI1 protein promotes the reaction [Methamphetamine results in increased expression of TNF protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TNF protein] Methamphetamine results in increased expression of TNF mRNA; Methamphetamine results in increased expression of TNF protein TNF protein results in increased susceptibility to Methamphetamine Lactulose inhibits the reaction [Methamphetamine results in increased expression of TNF protein]; margatoxin inhibits the reaction [Methamphetamine results in increased secretion of TNF protein]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of TNF mRNA]; Metformin inhibits the reaction [Methamphetamine results in increased expression of TNF protein] TNF protein affects the susceptibility to Methamphetamine |
CTD |
PMID:11746378 PMID:12230306 PMID:14999072 PMID:16828290 PMID:20374443 PMID:21276779 PMID:24533129 PMID:26283214 PMID:27288563 PMID:30450033 PMID:30742852 PMID:32569805 PMID:32768653 PMID:32916201 PMID:33359793 PMID:35390362 PMID:35688268 PMID:36720452 PMID:36914120 More...
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NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336
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G |
TNFAIP6 |
TNF alpha induced protein 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TNFAIP6 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046
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TNFRSF12A |
TNF receptor superfamily member 12A |
increases expression |
ISO |
Methamphetamine results in increased expression of TNFRSF12A mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,383
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G |
TNNI1 |
troponin I1, slow skeletal type |
increases expression |
ISO |
Methamphetamine results in increased expression of TNNI1 mRNA |
CTD |
PMID:15644446 |
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NCBI chr 1:201,403,784...201,421,730
Ensembl chr 1:201,403,784...201,429,866
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G |
TNNI3 |
troponin I3, cardiac type |
increases expression |
EXP ISO |
Methamphetamine results in increased expression of TNNI3 protein |
CTD |
PMID:16338525 PMID:35863504 |
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NCBI chr19:55,151,767...55,157,732
Ensembl chr19:55,151,767...55,157,773
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G |
TNPO1 |
transportin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TNPO1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:72,816,661...72,914,388
Ensembl chr 5:72,816,312...72,916,733
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TNRC6A |
trinucleotide repeat containing adaptor 6A |
increases expression |
ISO |
Methamphetamine results in increased expression of TNRC6A mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:24,610,205...24,826,218
Ensembl chr16:24,610,209...24,827,632
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G |
TNS1 |
tensin 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TNS1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:217,799,791...218,033,982
Ensembl chr 2:217,799,588...218,033,982
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G |
TNS2 |
tensin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of TNS2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:53,046,991...53,064,379
Ensembl chr12:53,046,969...53,064,379
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G |
TOB2 |
transducer of ERBB2, 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TOB2 mRNA |
CTD |
PMID:36914120 |
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NCBI chr22:41,433,494...41,446,801
Ensembl chr22:41,433,494...41,446,801
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G |
TOE1 |
target of EGR1, exonuclease |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TOE1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:45,340,170...45,343,973
Ensembl chr 1:45,340,052...45,343,973
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G |
TOMM20L |
translocase of outer mitochondrial membrane 20 like |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TOMM20L mRNA |
CTD |
PMID:26307267 |
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NCBI chr14:58,395,930...58,417,080
Ensembl chr14:58,395,928...58,408,702
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G |
TOP2A |
DNA topoisomerase II alpha |
decreases expression |
EXP ISO |
Methamphetamine results in decreased expression of TOP2A mRNA Methamphetamine results in decreased expression of TOP2A mRNA; Methamphetamine results in decreased expression of TOP2A protein |
CTD |
PMID:25290377 PMID:28341135 |
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NCBI chr17:40,388,525...40,417,896
Ensembl chr17:40,388,525...40,417,896
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G |
TP53 |
tumor protein p53 |
increases expression multiple interactions affects response to substance |
ISO |
Methamphetamine results in increased expression of TRP53 protein; Methamphetamine results in increased expression of TRP53 protein modified form Methamphetamine results in increased expression of TP53 protein Luteolin inhibits the reaction [Methamphetamine results in increased expression of TP53 protein] TRP53 protein affects the susceptibility to Methamphetamine NOS1 protein affects the reaction [Methamphetamine results in increased expression of TRP53 protein]; SOD1 protein affects the reaction [Methamphetamine results in increased expression of TRP53 protein]; TRP53 protein affects the reaction [Methamphetamine affects the expression of SLC6A4 protein] |
CTD |
PMID:9369336 PMID:11457507 PMID:12050851 PMID:17234339 PMID:32035215 PMID:32676729 More...
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NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538
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G |
TP53I11 |
tumor protein p53 inducible protein 11 |
increases expression |
ISO |
Methamphetamine results in increased expression of TRP53I11 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:44,932,348...44,951,306
Ensembl chr11:44,885,903...44,951,306
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G |
TPH2 |
tryptophan hydroxylase 2 |
affects response to substance |
ISO |
TPH2 protein affects the susceptibility to Methamphetamine |
CTD |
PMID:20722968 |
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NCBI chr12:71,938,845...72,032,440
Ensembl chr12:71,938,845...72,186,618
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G |
TPI1 |
triosephosphate isomerase 1 |
affects expression |
ISO |
Methamphetamine affects the expression of TPI1 protein |
CTD |
PMID:19826936 |
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NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948
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G |
TPX2 |
TPX2 microtubule nucleation factor |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of TPX2 promoter |
CTD |
PMID:26307267 |
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NCBI chr20:31,739,290...31,801,800
Ensembl chr20:31,739,271...31,801,805
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G |
TRAF6 |
TNF receptor associated factor 6 |
multiple interactions increases expression |
ISO |
Lactulose inhibits the reaction [Methamphetamine results in increased expression of TRAF6 protein] Methamphetamine results in increased expression of TRAF6 mRNA; Methamphetamine results in increased expression of TRAF6 protein [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TRAF6 mRNA]; [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased expression of TRAF6 protein]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TRAF6 mRNA]; TLR4 gene mutant form inhibits the reaction [Methamphetamine results in increased expression of TRAF6 protein] |
CTD |
PMID:30450033 PMID:35390362 |
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NCBI chr11:36,483,769...36,510,272
Ensembl chr11:36,483,769...36,510,272
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G |
TRAPPC12 |
trafficking protein particle complex subunit 12 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TRAPPC12 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:3,379,694...3,479,565
Ensembl chr 2:3,379,675...3,485,094
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G |
TREM2 |
triggering receptor expressed on myeloid cells 2 |
decreases expression increases expression |
ISO |
Methamphetamine results in decreased expression of TREM2 mRNA Methamphetamine results in increased expression of TREM2 mRNA; Methamphetamine results in increased expression of TREM2 protein |
CTD |
PMID:19564919 PMID:35643125 |
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NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186
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G |
TRIB3 |
tribbles pseudokinase 3 |
multiple interactions increases expression |
EXP ISO |
CEBPB protein affects the reaction [Methamphetamine results in increased expression of TRIB3 protein]; TRIB3 protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein]; TRIB3 protein affects the reaction [Methamphetamine results in increased expression of SNCA protein] |
CTD |
PMID:31059759 |
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NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559
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G |
TRIM63 |
tripartite motif containing 63 |
increases expression |
ISO |
Methamphetamine results in increased expression of TRIM63 mRNA |
CTD |
PMID:23933405 |
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NCBI chr 1:26,051,301...26,067,630
Ensembl chr 1:26,051,301...26,068,436
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G |
TRIM67 |
tripartite motif containing 67 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TRIM67 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:231,162,058...231,221,565
Ensembl chr 1:231,162,058...231,221,565
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G |
TRIP10 |
thyroid hormone receptor interactor 10 |
increases expression |
ISO |
Methamphetamine results in increased expression of TRIP10 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:6,739,680...6,751,530
Ensembl chr19:6,737,925...6,751,530
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G |
TRMT1 |
tRNA methyltransferase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TRMT1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:13,104,907...13,116,740
Ensembl chr19:13,104,902...13,117,567
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G |
TRNP1 |
TMF1 regulated nuclear protein 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TRNP1 mRNA |
CTD |
PMID:28341135 |
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NCBI chr 1:26,993,692...27,000,886
Ensembl chr 1:26,993,692...27,000,886
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G |
TRPM3 |
transient receptor potential cation channel subfamily M member 3 |
affects response to substance |
EXP |
TRPM3 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 9:70,529,060...71,446,971
Ensembl chr 9:70,529,060...71,446,904
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G |
TRPV1 |
transient receptor potential cation channel subfamily V member 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of TRPV1 mRNA |
CTD |
PMID:20122992 |
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NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
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G |
TSC2 |
TSC complex subunit 2 |
increases phosphorylation multiple interactions |
EXP ISO |
Methamphetamine results in increased phosphorylation of TSC2 protein CEBPB protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein] DDIT4 protein affects the reaction [Methamphetamine results in increased phosphorylation of TSC2 protein] |
CTD |
PMID:31059759 |
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NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491
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G |
TSC22D3 |
TSC22 domain family member 3 |
increases expression decreases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of TSC22D3 mRNA Methamphetamine results in decreased expression of TSC22D3 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of TSC22D3 mRNA |
CTD |
PMID:19564919 PMID:36914120 |
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NCBI chr X:107,713,221...107,775,988
Ensembl chr X:107,713,221...107,777,342
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G |
TSPAN4 |
tetraspanin 4 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TSPAN4 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr11:842,852...867,111
Ensembl chr11:842,812...867,116
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G |
TTC39A |
tetratricopeptide repeat domain 39A |
increases expression |
ISO |
Methamphetamine results in increased expression of TTC39A mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:51,287,258...51,345,116
Ensembl chr 1:51,287,258...51,345,116
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G |
TTC39B |
tetratricopeptide repeat domain 39B |
increases expression |
ISO |
Methamphetamine results in increased expression of TTC39B mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:15,163,622...15,307,216
Ensembl chr 9:15,163,622...15,307,360
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G |
TTK |
TTK protein kinase |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TTK mRNA Methamphetamine results in decreased expression of TTK mRNA |
CTD |
PMID:19564919 |
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NCBI chr 6:80,004,649...80,042,527
Ensembl chr 6:80,003,887...80,042,527
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G |
TTLL12 |
tubulin tyrosine ligase like 12 |
increases expression |
ISO |
Methamphetamine results in increased expression of TTLL12 mRNA |
CTD |
PMID:19564919 |
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NCBI chr22:43,166,622...43,187,134
Ensembl chr22:43,166,622...43,187,134
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G |
TTLL4 |
tubulin tyrosine ligase like 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of TTLL4 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:218,710,835...218,759,724
Ensembl chr 2:218,710,835...218,755,416
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G |
TTLL9 |
tubulin tyrosine ligase like 9 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of TTLL9 mRNA Methamphetamine results in decreased expression of TTLL9 mRNA |
CTD |
PMID:19564919 |
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NCBI chr20:31,870,634...31,945,000
Ensembl chr20:31,870,634...31,945,000
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G |
TTN |
titin |
increases expression |
ISO |
Methamphetamine results in increased expression of TTN mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:178,525,989...178,807,423
Ensembl chr 2:178,525,989...178,830,802
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G |
TTPAL |
alpha tocopherol transfer protein like |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of TTPAL promoter |
CTD |
PMID:26307267 |
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NCBI chr20:44,475,874...44,494,603
Ensembl chr20:44,475,874...44,494,603
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G |
TUBA1B |
tubulin alpha 1b |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TUBA1B protein |
CTD |
PMID:19826936 |
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NCBI chr12:49,127,782...49,131,395
Ensembl chr12:49,127,782...49,131,397
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G |
TUBA1C |
tubulin alpha 1c |
increases expression |
ISO |
Methamphetamine results in increased expression of TUBA1C mRNA |
CTD |
PMID:36914120 |
|
NCBI chr12:49,227,926...49,274,600
Ensembl chr12:49,188,736...49,274,600
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G |
TUBB |
tubulin beta class I |
increases expression |
ISO |
Methamphetamine results in increased expression of TUBB5 protein |
CTD |
PMID:19826936 |
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NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538
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G |
TUBB2A |
tubulin beta 2A class IIa |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TUBB2A protein |
CTD |
PMID:19826936 |
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NCBI chr 6:3,153,666...3,157,544
Ensembl chr 6:3,153,497...3,157,544
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G |
TUBB4B |
tubulin beta 4B class IVb |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TUBB4B protein |
CTD |
PMID:19826936 |
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NCBI chr 9:137,241,287...137,243,707
Ensembl chr 9:137,241,287...137,243,707
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G |
TUFM |
Tu translation elongation factor, mitochondrial |
decreases expression |
ISO |
Methamphetamine results in decreased expression of TUFM protein |
CTD |
PMID:19826936 |
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NCBI chr16:28,842,411...28,846,348
Ensembl chr16:28,842,411...28,846,348
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G |
TUT1 |
terminal uridylyl transferase 1, U6 snRNA-specific |
increases expression |
ISO |
Methamphetamine results in increased expression of TUT1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:62,575,052...62,591,523
Ensembl chr11:62,575,045...62,591,637
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G |
TXN |
thioredoxin |
decreases expression multiple interactions decreases response to substance |
ISO EXP |
Methamphetamine results in decreased expression of TXN1 protein TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP12 protein]; TXN protein inhibits the reaction [Methamphetamine results in decreased expression of CASP3 protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of BAX protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of DDIT3 protein]; TXN protein inhibits the reaction [Methamphetamine results in increased expression of HSPA5 protein] TXN protein results in decreased susceptibility to Methamphetamine |
CTD |
PMID:32203791 |
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NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507
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G |
UBA1 |
ubiquitin like modifier activating enzyme 1 |
multiple interactions decreases expression affects localization |
ISO |
2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine inhibits the reaction [Methamphetamine affects the localization of UBA1 mRNA] Methamphetamine results in decreased expression of UBA1 mRNA |
CTD |
PMID:18299792 |
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NCBI chr X:47,190,847...47,215,128
Ensembl chr X:47,190,861...47,215,128
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G |
UBA2 |
ubiquitin like modifier activating enzyme 2 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of UBA2 mRNA Methamphetamine results in increased expression of UBA2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:34,428,381...34,471,251
Ensembl chr19:34,428,352...34,471,251
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G |
UBC |
ubiquitin C |
increases expression |
ISO |
Methamphetamine results in increased expression of UBC mRNA |
CTD |
PMID:24042092 |
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NCBI chr12:124,911,646...124,914,650
Ensembl chr12:124,911,604...124,917,368
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G |
UBE2C |
ubiquitin conjugating enzyme E2 C |
decreases expression |
ISO |
Methamphetamine results in decreased expression of UBE2C mRNA |
CTD |
PMID:28341135 |
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NCBI chr20:45,812,644...45,816,952
Ensembl chr20:45,812,576...45,816,957
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G |
UBE2N |
ubiquitin conjugating enzyme E2 N |
affects expression |
ISO |
Methamphetamine affects the expression of UBE2N protein |
CTD |
PMID:17904249 |
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NCBI chr12:93,405,684...93,441,947
Ensembl chr12:93,405,673...93,441,947
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G |
UBE2T |
ubiquitin conjugating enzyme E2 T |
decreases expression |
ISO |
Methamphetamine results in decreased expression of UBE2T mRNA |
CTD |
PMID:28341135 |
|
NCBI chr 1:202,331,657...202,341,936
Ensembl chr 1:202,331,544...202,341,984
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G |
UBL4B |
ubiquitin like 4B |
decreases expression |
ISO |
Methamphetamine results in decreased expression of UBL4B mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:110,112,443...110,113,947
Ensembl chr 1:110,112,443...110,113,947
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G |
UBR2 |
ubiquitin protein ligase E3 component n-recognin 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of UBR2 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 6:42,564,029...42,693,505
Ensembl chr 6:42,564,029...42,693,505
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G |
UBR4 |
ubiquitin protein ligase E3 component n-recognin 4 |
increases expression |
ISO |
Methamphetamine results in increased expression of UBR4 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 1:19,074,510...19,210,266
Ensembl chr 1:19,074,510...19,210,266
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G |
UCHL1 |
ubiquitin C-terminal hydrolase L1 |
decreases expression increases expression |
ISO |
Methamphetamine results in decreased expression of UCHL1 protein Methamphetamine results in increased expression of UCHL1 protein |
CTD |
PMID:16181420 PMID:19826936 |
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NCBI chr 4:41,256,928...41,268,455
Ensembl chr 4:41,256,413...41,268,455
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G |
UCK2 |
uridine-cytidine kinase 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of UCK2 mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 1:165,827,614...165,911,618
Ensembl chr 1:165,827,614...165,911,618
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G |
ULK1 |
unc-51 like autophagy activating kinase 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ULK1 |
CTD |
PMID:32676729 |
|
NCBI chr12:131,894,622...131,923,150
Ensembl chr12:131,894,622...131,923,150
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G |
UNK |
unk zinc finger |
increases expression |
ISO |
Methamphetamine results in increased expression of UNK mRNA |
CTD |
PMID:26307267 |
|
NCBI chr17:75,784,806...75,825,799
Ensembl chr17:75,784,806...75,825,799
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G |
UPP1 |
uridine phosphorylase 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of UPP1 mRNA Methamphetamine results in increased expression of UPP1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr 7:48,088,704...48,108,736
Ensembl chr 7:48,088,628...48,108,736
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G |
URGCP |
upregulator of cell proliferation |
increases expression |
ISO |
Methamphetamine results in increased expression of URGCP mRNA |
CTD |
PMID:36914120 |
|
NCBI chr 7:43,875,913...43,926,726
Ensembl chr 7:43,875,894...43,926,411
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G |
USH1C |
USH1 protein network component harmonin |
increases expression |
ISO |
Methamphetamine results in increased expression of USH1C mRNA |
CTD |
PMID:26307267 |
|
NCBI chr11:17,493,900...17,544,416
Ensembl chr11:17,493,895...17,544,416
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G |
USH2A |
usherin |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of USH2A promoter |
CTD |
PMID:26307267 |
|
NCBI chr 1:215,622,891...216,423,448
Ensembl chr 1:215,622,891...216,423,448
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G |
USP20 |
ubiquitin specific peptidase 20 |
increases expression |
ISO |
Methamphetamine results in increased expression of USP20 mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 9:129,835,458...129,881,828
Ensembl chr 9:129,834,698...129,881,828
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G |
USP48 |
ubiquitin specific peptidase 48 |
affects response to substance |
EXP |
USP48 gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
|
NCBI chr 1:21,678,298...21,783,149
Ensembl chr 1:21,678,298...21,783,606
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G |
USPL1 |
ubiquitin specific peptidase like 1 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of USPL1 mRNA Methamphetamine results in increased expression of USPL1 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr13:30,617,920...30,660,766
Ensembl chr13:30,617,693...30,660,770
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G |
UTP18 |
UTP18 small subunit processome component |
decreases expression |
ISO |
Methamphetamine results in decreased expression of UTP18 mRNA |
CTD |
PMID:19564919 |
|
NCBI chr17:51,260,546...51,297,933
Ensembl chr17:51,260,546...51,297,936
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G |
UTRN |
utrophin |
increases expression |
ISO |
Methamphetamine results in increased expression of UTRN mRNA |
CTD |
PMID:26307267 |
|
NCBI chr 6:144,285,335...144,853,034
Ensembl chr 6:144,285,335...144,853,034
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G |
VAMP8 |
vesicle associated membrane protein 8 |
increases expression |
ISO |
Methamphetamine results in increased expression of VAMP8 mRNA |
CTD |
PMID:34374793 |
|
NCBI chr 2:85,577,586...85,582,031
Ensembl chr 2:85,561,562...85,582,031
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G |
VDAC1 |
voltage dependent anion channel 1 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of VDAC1 protein |
CTD |
PMID:19826936 |
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NCBI chr 5:133,971,871...134,114,540
Ensembl chr 5:133,971,871...134,004,975
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VDAC2 |
voltage dependent anion channel 2 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of VDAC2 protein |
CTD |
PMID:19826936 |
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NCBI chr10:75,210,170...75,231,448
Ensembl chr10:75,210,154...75,231,448
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VEGFA |
vascular endothelial growth factor A |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of VEGFA mRNA SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of VEGFA mRNA] |
CTD |
PMID:15644446 PMID:19564919 |
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NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487
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G |
VGF |
VGF nerve growth factor inducible |
increases expression |
ISO |
Methamphetamine results in increased expression of VGF mRNA |
CTD |
PMID:19564919 |
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NCBI chr 7:101,162,509...101,169,952
Ensembl chr 7:101,162,509...101,165,569
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VLDLR |
very low density lipoprotein receptor |
increases expression |
ISO |
Methamphetamine results in increased expression of VLDLR mRNA |
CTD |
PMID:26307267 |
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NCBI chr 9:2,621,787...2,660,056
Ensembl chr 9:2,621,182...2,660,056
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G |
VPS11 |
VPS11 core subunit of CORVET and HOPS complexes |
increases expression |
ISO |
Methamphetamine results in increased expression of VPS11 mRNA |
CTD |
PMID:26307267 |
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NCBI chr11:119,067,818...119,081,972
Ensembl chr11:119,067,818...119,081,972
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G |
VPS29 |
VPS29 retromer complex component |
decreases expression |
ISO |
Methamphetamine results in decreased expression of VPS29 mRNA |
CTD |
PMID:26307267 |
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NCBI chr12:110,491,083...110,502,111
Ensembl chr12:110,491,083...110,502,111
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G |
VPS35 |
VPS35 retromer complex component |
increases expression |
ISO |
Methamphetamine results in increased expression of VPS35 mRNA; Methamphetamine results in increased expression of VPS35 protein |
CTD |
PMID:35643125 |
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NCBI chr16:46,656,132...46,689,178
Ensembl chr16:46,656,132...46,689,518
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VPS37B |
VPS37B subunit of ESCRT-I |
increases expression |
ISO |
Methamphetamine results in increased expression of VPS37B mRNA |
CTD |
PMID:19564919 |
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NCBI chr12:122,865,330...122,896,124
Ensembl chr12:122,865,330...122,896,127
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G |
VWF |
von Willebrand factor |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of VWF mRNA Luteolin inhibits the reaction [Methamphetamine results in increased expression of VWF mRNA] |
CTD |
PMID:32035215 |
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NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770
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G |
VXN |
vexin |
increases expression |
ISO |
Methamphetamine results in increased expression of VXN mRNA |
CTD |
PMID:32035215 |
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NCBI chr 8:66,493,566...66,518,524
Ensembl chr 8:66,492,326...66,518,524
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G |
WASF2 |
WASP family member 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of WASF2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:27,404,230...27,490,167
Ensembl chr 1:27,404,230...27,490,167
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G |
WASHC2C |
WASH complex subunit 2C |
decreases methylation increases expression |
ISO |
Methamphetamine results in decreased methylation of WASHC2 promoter Methamphetamine results in increased expression of WASHC2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr10:45,727,043...45,792,964
Ensembl chr10:45,727,200...45,792,964
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G |
WWC2 |
WW and C2 domain containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of WWC2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 4:183,099,257...183,320,777
Ensembl chr 4:183,099,257...183,320,777
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G |
XBP1 |
X-box binding protein 1 |
multiple interactions increases expression |
ISO EXP |
4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased expression of XBP1 protein alternative form]; Melatonin inhibits the reaction [Methamphetamine results in increased expression of XBP1 mRNA alternative form]; Methamphetamine results in increased expression of and results in increased splicing of XBP1 mRNA; SCH 23390 inhibits the reaction [Methamphetamine results in increased splicing of XBP1 mRNA] Methamphetamine results in increased expression of XBP1 mRNA; Methamphetamine results in increased expression of XBP1 protein ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 mRNA]; ATF6 protein affects the reaction [Methamphetamine results in increased expression of XBP1 protein] Methamphetamine results in increased expression of XBP1 mRNA; Methamphetamine results in increased expression of XBP1 mRNA alternative form; Methamphetamine results in increased expression of XBP1 protein alternative form |
CTD |
PMID:19564919 PMID:27323860 PMID:28070110 PMID:34214594 |
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NCBI chr22:28,794,560...28,800,569
Ensembl chr22:28,794,555...28,800,597
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XDH |
xanthine dehydrogenase |
increases expression |
ISO |
Methamphetamine results in increased expression of XDH mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742
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G |
XIRP1 |
xin actin binding repeat containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of XIRP1 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 3:39,183,215...39,192,595
Ensembl chr 3:39,183,210...39,192,596
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G |
XPO6 |
exportin 6 |
increases expression |
ISO |
Methamphetamine results in increased expression of XPO6 mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:28,097,976...28,211,965
Ensembl chr16:28,097,976...28,211,965
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G |
XRCC1 |
X-ray repair cross complementing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of XRCC1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473
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G |
XRN1 |
5'-3' exoribonuclease 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of XRN1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 3:142,306,610...142,448,037
Ensembl chr 3:142,306,607...142,448,062
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G |
YBX1 |
Y-box binding protein 1 |
increases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of YBX1 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of YBX1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:42,682,418...42,703,805
Ensembl chr 1:42,682,418...42,703,805
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G |
YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta |
decreases expression |
ISO |
Methamphetamine results in decreased expression of YWHAB mRNA |
CTD |
PMID:26307267 |
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NCBI chr20:44,885,705...44,908,532
Ensembl chr20:44,885,702...44,908,532
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G |
ZBTB40 |
zinc finger and BTB domain containing 40 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ZBTB40 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:22,428,909...22,531,154
Ensembl chr 1:22,428,838...22,531,157
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G |
ZC3H11A |
zinc finger CCCH-type containing 11A |
increases expression |
ISO |
Methamphetamine results in increased expression of ZC3H11A mRNA |
CTD |
PMID:26307267 |
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NCBI chr 1:203,795,623...203,854,124
Ensembl chr 1:203,795,623...203,854,999
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G |
ZC3H6 |
zinc finger CCCH-type containing 6 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ZC3H6 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 2:112,275,597...112,340,059
Ensembl chr 2:112,275,597...112,340,059
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G |
ZCCHC12 |
zinc finger CCHC-type containing 12 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ZCCHC12 mRNA |
CTD |
PMID:32035215 |
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NCBI chr X:118,823,824...118,826,968
Ensembl chr X:118,823,824...118,826,968
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G |
ZDHHC3 |
zinc finger DHHC-type palmitoyltransferase 3 |
decreases methylation |
ISO |
Methamphetamine results in decreased methylation of ZDHHC3 promoter |
CTD |
PMID:26307267 |
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NCBI chr 3:44,915,261...44,976,174
Ensembl chr 3:44,915,257...44,976,185
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G |
ZFAND2A |
zinc finger AN1-type containing 2A |
increases expression |
ISO |
Methamphetamine results in increased expression of ZFAND2A mRNA |
CTD |
PMID:19564919 |
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NCBI chr 7:1,148,850...1,160,196
Ensembl chr 7:1,152,071...1,160,759
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G |
ZFP1 |
ZFP1 zinc finger protein |
increases expression |
ISO |
Methamphetamine results in increased expression of ZFP1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:75,119,002...75,172,234
Ensembl chr16:75,148,494...75,172,236
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G |
ZFP36 |
ZFP36 ring finger protein |
increases expression decreases expression multiple interactions |
ISO |
Methamphetamine results in increased expression of ZFP36 mRNA Methamphetamine results in decreased expression of ZFP36 mRNA [Methamphetamine co-treated with SCH 23390] results in increased expression of ZFP36 mRNA |
CTD |
PMID:19564919 PMID:26307267 PMID:36914120 |
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NCBI chr19:39,406,847...39,409,407
Ensembl chr19:39,406,847...39,409,412
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G |
ZFP36L1 |
ZFP36 ring finger protein like 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ZFP36L1 mRNA |
CTD |
PMID:19564919 |
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NCBI chr14:68,787,655...68,796,243
Ensembl chr14:68,787,660...68,796,253
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G |
ZFYVE16 |
zinc finger FYVE-type containing 16 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ZFYVE16 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:80,407,610...80,483,379
Ensembl chr 5:80,408,013...80,483,379
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G |
ZIC2 |
Zic family member 2 |
decreases expression multiple interactions |
ISO |
Methamphetamine results in decreased expression of ZIC2 mRNA [Methamphetamine co-treated with SCH 23390] results in decreased expression of ZIC2 mRNA |
CTD |
PMID:19564919 |
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NCBI chr13:99,981,784...99,986,765
Ensembl chr13:99,981,784...99,986,765
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G |
ZMAT3 |
zinc finger matrin-type 3 |
increases expression affects response to substance |
ISO |
Methamphetamine results in increased expression of ZMAT3 protein ZMAT3 protein affects the susceptibility to Methamphetamine |
CTD |
PMID:17234339 |
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NCBI chr 3:179,017,223...179,072,513
Ensembl chr 3:178,960,121...179,072,215
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G |
ZMIZ2 |
zinc finger MIZ-type containing 2 |
increases expression |
ISO |
Methamphetamine results in increased expression of ZMIZ2 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:44,748,571...44,769,881
Ensembl chr 7:44,748,581...44,769,881
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G |
ZMYND12 |
zinc finger MYND-type containing 12 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ZMYND12 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 1:42,430,329...42,456,022
Ensembl chr 1:42,430,329...42,456,253
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G |
ZMYND8 |
zinc finger MYND-type containing 8 |
increases expression |
ISO |
Methamphetamine results in increased expression of ZMYND8 mRNA |
CTD |
PMID:26307267 |
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NCBI chr20:47,209,214...47,356,699
Ensembl chr20:47,209,214...47,356,889
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G |
ZNF142 |
zinc finger protein 142 |
increases expression |
ISO |
Methamphetamine results in increased expression of ZFP142 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:218,633,329...218,659,623
Ensembl chr 2:218,633,329...218,659,655
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G |
ZNF189 |
zinc finger protein 189 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in increased expression of ZFP189 mRNA Methamphetamine results in increased expression of ZFP189 mRNA |
CTD |
PMID:19564919 |
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NCBI chr 9:101,398,851...101,410,654
Ensembl chr 9:101,398,851...101,410,660
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G |
ZNF287 |
zinc finger protein 287 |
multiple interactions increases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ZFP287 mRNA Methamphetamine results in increased expression of ZFP287 mRNA |
CTD |
PMID:19564919 |
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NCBI chr17:16,546,954...16,569,212
Ensembl chr17:16,546,954...16,569,204
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G |
ZNF354A |
zinc finger protein 354A |
increases expression |
ISO |
Methamphetamine results in increased expression of ZFP354A mRNA |
CTD |
PMID:19564919 |
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NCBI chr 5:178,711,512...178,730,659
Ensembl chr 5:178,711,512...178,730,659
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G |
ZNF366 |
zinc finger protein 366 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ZFP366 mRNA |
CTD |
PMID:36914120 |
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NCBI chr 5:72,439,903...72,507,410
Ensembl chr 5:72,439,903...72,507,410
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G |
ZNF385D |
zinc finger protein 385D |
affects response to substance |
EXP |
ZNF385D gene SNP affects the susceptibility to Methamphetamine |
CTD |
PMID:18316681 |
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NCBI chr 3:21,412,218...22,372,763
Ensembl chr 3:21,412,218...22,373,321
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G |
ZNF414 |
zinc finger protein 414 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ZFP414 mRNA |
CTD |
PMID:19564919 |
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NCBI chr19:8,509,678...8,514,167
Ensembl chr19:8,509,678...8,514,167
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G |
ZNF532 |
zinc finger protein 532 |
increases expression |
ISO |
Methamphetamine results in increased expression of ZFP532 mRNA |
CTD |
PMID:26307267 |
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NCBI chr18:58,862,924...58,986,480
Ensembl chr18:58,862,600...58,986,480
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G |
ZNF541 |
zinc finger protein 541 |
decreases expression |
ISO |
Methamphetamine results in decreased expression of ZFP541 mRNA |
CTD |
PMID:26307267 |
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NCBI chr19:47,520,690...47,573,309
Ensembl chr19:47,520,690...47,573,148
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G |
ZNF609 |
zinc finger protein 609 |
increases expression |
ISO |
Methamphetamine results in increased expression of ZFP609 mRNA |
CTD |
PMID:26307267 |
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NCBI chr15:64,459,578...64,686,068
Ensembl chr15:64,460,578...64,686,068
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G |
ZNF638 |
zinc finger protein 638 |
increases expression |
ISO |
Methamphetamine results in increased expression of ZFP638 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 2:71,331,782...71,435,061
Ensembl chr 2:71,276,561...71,435,069
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G |
ZNF688 |
zinc finger protein 688 |
multiple interactions decreases expression |
ISO |
[Methamphetamine co-treated with SCH 23390] results in decreased expression of ZFP688 mRNA Methamphetamine results in decreased expression of ZFP688 mRNA |
CTD |
PMID:19564919 |
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NCBI chr16:30,569,726...30,579,951
Ensembl chr16:30,569,672...30,572,734
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G |
ZNF775 |
zinc finger protein 775 |
increases expression |
ISO |
Methamphetamine results in increased expression of ZFP775 mRNA |
CTD |
PMID:26307267 |
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NCBI chr 7:150,379,330...150,398,630
Ensembl chr 7:150,368,790...150,398,630
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G |
ZNFX1 |
zinc finger NFX1-type containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ZNFX1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr20:49,245,900...49,278,057
Ensembl chr20:49,237,946...49,278,426
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G |
ZNRF1 |
zinc and ring finger 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ZNRF1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr16:74,999,024...75,110,994
Ensembl chr16:74,999,024...75,110,994
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G |
ZZEF1 |
zinc finger ZZ-type and EF-hand domain containing 1 |
increases expression |
ISO |
Methamphetamine results in increased expression of ZZEF1 mRNA |
CTD |
PMID:26307267 |
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NCBI chr17:4,004,445...4,143,030
Ensembl chr17:4,004,445...4,143,030
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