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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10289
Species: Mus musculus
RGD Object: Gene
Symbol: Casp3
Name: caspase 3
Acc ID: CHEBI:32269
Term: tropisetron
Definition: An indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine.
Chemical ID: MESH:C045504
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Casp3increases expressionEXP 6480464CTDTropisetron results in increased expression of CASP3 protein modified formPMID:34654991
Casp3multiple interactionsEXP 6480464CTDPaclitaxel inhibits the reaction [Tropisetron results in increased expression of CASP3 protein modified form]PMID:34654991
Casp3increases expressionISOCASP3 (Homo sapiens)6480464CTDTropisetron results in increased expression of CASP3 protein modified formPMID:34654991
Casp3multiple interactionsISOCasp3 (Rattus norvegicus)6480464CTDTropisetron inhibits the reaction [Streptozocin results in increased expression of CASP3 protein]PMID:36504472
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