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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1344192
Species: Homo sapiens
RGD Object: Gene
Symbol: TNF
Name: tumor necrosis factor
Acc ID: CHEBI:135014
Term: erdosteine
Definition: null
Chemical ID: MESH:C048498
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TNFmultiple interactionsISOTnf (Mus musculus)6480464CTDerdosteine inhibits the reaction [Cisplatin results in increased expression of TNF mRNA]; erdosteine inhibits the reaction [Cisplatin results in increased expression of TNF protein]PMID:26193055
TNFmultiple interactionsISOTnf (Rattus norvegicus)6480464CTDerdosteine inhibits the reaction [Isoproterenol results in increased expression of TNF protein]; erdosteine inhibits the reaction [Nicotine results in increased expression of TNF protein]PMID:17216608 PMID:33210414
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