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GENE - TERM ANNOTATION REPORT

RGD ID: 12267832
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: IL1RN
Name: interleukin 1 receptor antagonist
Acc ID: DOID:2986
Term: IgA glomerulonephritis
Definition: A glomerulonephritis characterized by build up of IgA antibody in the glomerulus. (DO)
Definition Source(s): http://en.wikipedia.org/wiki/IgA_nephropathy "DO" "DO", http://www.nlm.nih.gov/medlineplus/ency/article/000466.htm "DO" "DO"
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IL1RN ISOIL1RN (Homo sapiens)9068941RGDDNA:repeats:intron:IVS2+914_1000dup IL1RN*2 (human)PMID:10916103 REF_RGD_ID:6906961
IL1RN ISOIL1RN (Homo sapiens)9068941RGDmouse model treated with human proteinPMID:9370186 REF_RGD_ID:6909150
IL1RN ISOIL1RN (Homo sapiens)9068941RGDprotein:decreased expression:serum, urine (human)PMID:16209246 REF_RGD_ID:6907414
IL1RN ISOIL1RN (Homo sapiens)9068941RGDrat model treated with human proteinPMID:10079261 REF_RGD_ID:6909131
IL1RN ISOIL1RN (Homo sapiens)9068941RGDresponse to immunoglobulin therapyPMID:9844059 REF_RGD_ID:6909132
IL1RN ISOIl1rn (Mus musculus)9068941RGD PMID:10566895 REF_RGD_ID:6907427
IL1RNsusceptibilityISOIL1RN (Homo sapiens)9068941RGDDNA:polymorphisms:intron, 3' utr:IVS1+1890G>T, IVS1+8796A>G, *138C>G (rs928940, rs439154, rs315951) (human)PMID:19280228 REF_RGD_ID:6907082
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