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GENE - TERM ANNOTATION REPORT

5 Annotations Found.

An association has been curated linking Lep and metabolic dysfunction-associated steatotic liver disease in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from Lu H, etal., J Gastroenterol Hepatol. 2009 Feb;24(2):228-32. Epub 2008 Aug 17.
  • The annotation has been inferred from sequence orthology with LEP (Homo sapiens) [(IEP) inferred from expression pattern]
  • 5 additional annotations were made from Lu H, etal., J Gastroenterol Hepatol. 2009 Feb;24(2):228-32. Epub 2008 Aug 17.
  • 223 RGD objects have been annotated to metabolic dysfunction-associated steatotic liver disease  (DOID:0080208)
  • 141 papers in RGD have been used to annotate Lep
  • Curation Notes: associated with Type 2 Diabetes Mellitus;protein:increased expression:plasma


    • An association has been curated linking Lep and metabolic dysfunction-associated steatotic liver disease in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Cernea S, etal., Diabetes Metab Res Rev. 2018 Nov;34(8):e3050. doi: 10.1002/dmrr.3050. Epub 2018 Sep 13.
  • 2 additional annotations were made from Cernea S, etal., Diabetes Metab Res Rev. 2018 Nov;34(8):e3050. doi: 10.1002/dmrr.3050. Epub 2018 Sep 13.
  • 223 RGD objects have been annotated to metabolic dysfunction-associated steatotic liver disease  (DOID:0080208)
  • 141 papers in RGD have been used to annotate Lep
  • Curation Notes: associated with type 2 diabetes mellitus;protein:increased expression:serum (human)


    • An association has been curated linking Lep and metabolic dysfunction-associated steatotic liver disease in Rattus norvegicus.        

  • The association was inferred from expression pattern (IEP)
    		•  
  • The annotation was made from Ashour E, etal., Clin Lab. 2010;56(3-4):103-10.
  • 2 additional annotations were made from Ashour E, etal., Clin Lab. 2010;56(3-4):103-10.
  • 223 RGD objects have been annotated to metabolic dysfunction-associated steatotic liver disease  (DOID:0080208)
  • 141 papers in RGD have been used to annotate Lep
  • Curation Notes: associated with Hepatitis C, Chronic;proteinLincreased expression:serum (human)


    • An association has been curated linking Lep and metabolic dysfunction-associated steatotic liver disease in Rattus norvegicus.        

  • The association was inferred from sequence orthology (ISO)
    		•  
  • The annotation was made from RGD automated import pipeline for CTD gene-to-disease annotations
  • The annotation has been inferred from sequence orthology with LEP (Homo sapiens) [(EXP) inferred from experiment]
  • 223 RGD objects have been annotated to metabolic dysfunction-associated steatotic liver disease  (DOID:0080208)
  • 141 papers in RGD have been used to annotate Lep
  • Curation Notes: CTD Direct Evidence: marker/mechanism
  • Original References(s): PMID:24211274 PMID:36105184


    • An association has been curated linking Lep and metabolic dysfunction-associated steatotic liver disease in Rattus norvegicus.        

  • The association was inferred from sequence or structural similarity (ISS)
    		•  
  • The annotation was made from RGD automated import pipeline for MGI gene-to-disease annotations
  • The annotation has been inferred from sequence or structural similarity with Lep (Mus musculus) [(IAGP) inferred by association of genotype and phenotype]
  • 223 RGD objects have been annotated to metabolic dysfunction-associated steatotic liver disease  (DOID:0080208)
  • 141 papers in RGD have been used to annotate Lep
  • Curation Notes: OMIM:613282 | OMIM:613387


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