| F344/DuCrlCrlj |
plasma glucose level |
fasting (for 12 hours) then glucose solution, 2.8M (2 g/kg) |
Ogino Genom 2000 Nov 15;70(1):19-25. |
blood glucose amount |
male |
245.0 days
| 15 |
|
80.0 |
mg/dl |
1.24 |
4.8 |
oral glucose tolerance test |
tail vein |
0 |
gastric gavage |
|
min |
|
converted from mg/dl |
11404 |
83 |
| F344/DuCrlCrlj |
abdominal fat pad weight |
control condition |
Ogino Genom 2000 Nov 15;70(1):19-25. |
abdominal fat pad mass |
male |
252.0 days
| 15 |
|
33.4 |
g |
0.85 |
3.3 |
post excision weight measurement |
|
|
|
|
|
|
|
11412 |
83 |
| F344/DuCrlCrlj |
mesenteric fat pad weight |
control condition |
Ogino Genom 2000 Nov 15;70(1):19-25. |
mesenteric fat pad mass |
male |
252.0 days
| 15 |
|
11.5 |
g |
0.34 |
1.3 |
post excision weight measurement |
|
0.0 |
|
|
|
|
|
11413 |
83 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65.0 days
| 15 |
|
169.2 |
mg/dl |
5.4 |
20.91 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11458 |
85 |
| F344/DuCrlCrlj |
body weight |
control condition (for 185 days) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
body mass |
male |
185.0 days
| 9 |
|
365.0 |
g |
9.0 |
27.0 |
body weighing method |
|
0.0 |
|
|
|
|
|
11486 |
85 |
| F344/DuCrlCrlj |
plasma glucose level |
fasting (for 16 hours) then glucose solution, 2.8M (2 g/kg) |
Moralejo DH, et al., Proc Assoc Am Physicians 1998 Nov-Dec;110(6):545-58 |
blood glucose amount |
male |
210.0 days
| 7 |
|
104.0 |
mg/dl |
6.1 |
16.14 |
oral glucose tolerance test |
tail |
|
glucose challenge by gastric gavage |
|
min |
Glucose-B Test Kit (Wako Pure Chemical Industries, Ltd., Osaka, Japan) |
|
13201 |
228 |
| F344/DuCrlCrlj |
plasma glucose level |
fasting (for 16 hours) then glucose solution, 2.8M (2 g/kg) |
Moralejo DH, et al., Proc Assoc Am Physicians 1998 Nov-Dec;110(6):545-58 |
blood glucose amount |
male |
210.0 days
| 7 |
|
124.1 |
mg/dl |
1.6 |
4.23 |
oral glucose tolerance test |
tail |
|
glucose challenge by gastric gavage |
30 |
min |
Glucose-B Test Kit (Wako Pure Chemical Industries, Ltd., Osaka, Japan) |
|
13202 |
228 |
| F344/DuCrlCrlj |
retroperitoneal fat pad weight |
control condition |
Muramatsu Y, et al., Biochem Biophys Res Commun 2005 Jun 17;331(4):1270-6. |
retroperitoneal fat pad mass |
male |
245.0 days
| 12 |
|
11.7 |
g |
0.2 |
0.7 |
post excision weight measurement |
|
|
|
|
|
|
|
12434 |
262 |
| F344/DuCrlCrlj |
abdominal fat pad weight |
control condition |
Muramatsu Y, et al., Biochem Biophys Res Commun 2005 Jun 17;331(4):1270-6. |
abdominal fat pad mass |
male |
245.0 days
| 12 |
|
34.4 |
g |
0.66 |
2.3 |
post excision weight measurement |
|
|
|
|
|
|
|
12436 |
262 |
| F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95.0 days
| 15 |
|
0.07 |
mg/dl |
0.01 |
0.04 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
67637 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95.0 days
| 20 |
|
90.0 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
|
min |
|
|
67647 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95.0 days
| 20 |
|
118.8 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
60 |
min |
|
|
67650 |
85 |
| F344/DuCrlCrlj |
both kidneys wet weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70.0 days
| 6 |
|
0.61 |
% |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71578 |
41 |
| F344/DuCrlCrlj |
mean corpuscular hemoglobin concentration |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70.0 days
| 6 |
|
31.2 |
g/dl |
0.41 |
1.0 |
automated cell/particle size/count analysis method |
|
|
|
|
|
Sysmex, F-800 type |
|
76882 |
1498 |
| F344/DuCrlCrlj |
plasma total protein level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood total protein amount |
male |
70.0 days
| 6 |
|
59.0 |
mg/ml |
0.82 |
2.0 |
automated plasma total protein analysis |
|
|
|
|
|
Hitachi, model 7170 |
|
76890 |
1498 |
| F344/DuCrlCrlj |
plasma total cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood cholesterol amount |
male |
70.0 days
| 6 |
|
49.0 |
mg/dl |
1.63 |
4.0 |
automated plasma analysis |
|
|
|
|
|
PMID:15591307 |
|
76894 |
1498 |
| F344/DuCrlCrlj |
plasma urea nitrogen level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood urea nitrogen amount |
male |
70.0 days
| 6 |
|
7.07 |
mmol/l |
0.15 |
0.36 |
automated plasma analysis |
|
|
|
|
|
PMID:15591307 |
|
76899 |
1498 |
| F344/DuCrlCrlj |
total plasma calcium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood calcium amount |
male |
70.0 days
| 6 |
|
10.3 |
mg/dl |
0.04 |
0.1 |
automated blood electrolyte analysis |
|
|
|
|
|
Hitachi, model 7170 |
|
76902 |
1498 |
| F344/DuCrlCrlj |
plasma sodium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood sodium amount |
male |
70.0 days
| 6 |
|
148.8 |
mmol/l |
0.45 |
1.1 |
automated blood electrolyte analysis |
|
|
|
|
|
Analytical intruments, PVA alpha II |
|
76903 |
1498 |
| F344/DuCrlCrlj |
blood lymphocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
lymphocyte quantity |
male |
70.0 days
| 6 |
|
81.0 |
% |
2.45 |
6.0 |
automated differential white blood cell count test |
|
|
|
|
|
May-Giemsa staining |
|
76910 |
1498 |
| F344/DuCrlCrlj |
blood monocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
monocyte quantity |
male |
70.0 days
| 6 |
|
5.0 |
% |
1.22 |
3.0 |
automated differential white blood cell count test |
|
|
|
|
|
May-Giemsa staining |
|
76911 |
1498 |
| F344/DuCrlCrlj |
urine potassium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63.0 days
| 6 |
|
143.0 |
uEq/100g/6 hrs |
10.61 |
26.0 |
automated urine analysis |
|
|
|
|
|
Analytical intruments, PVA alpha II |
|
94873 |
1662 |
| F344/DuCrlCrlj |
urine chloride excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63.0 days
| 6 |
|
274.0 |
uEq/100g/6 hrs |
22.45 |
55.0 |
automated urine analysis |
|
|
|
|
|
|
|
94875 |
1662 |
| F344/DuCrlCrlj |
blood glucose level area under curve (AUC) |
fasting (for 16 hours) then glucose solution, 2.8M (2 g/kg) |
Moralejo DH, et al., Proc Assoc Am Physicians 1998 Nov-Dec;110(6):545-58 |
blood glucose amount |
male |
210.0 days
| 7 |
|
15300.0 |
(mg/dl) x min |
206.7 |
546.88 |
oral glucose tolerance test |
tail |
0.0 |
gastric gavage |
|
|
Glucose-B Test Kit (Wako Pure Chemical Industries, Ltd., Osaka, Japan) |
|
67194 |
228 |
| F344/DuCrlCrlj |
blood glucose level |
partial pancreatectomy (70 %) |
Ogino GenetRes 73:29 '99 |
blood glucose amount |
male |
49.0 days
| 9 |
|
123.4 |
mg/dl |
2.2 |
6.6 |
blood glucose test strip read by electrochemical glucometer |
tail |
0.0 |
post pancreatectomy |
7 |
days |
Toecho Super, Kyoto Daiichi Kagaku, Kyoto, Japan |
converted from mg/dl |
11419 |
84 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95.0 days
| 15 |
|
91.8 |
mg/dl |
1.8 |
6.97 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
|
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11428 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65.0 days
| 15 |
|
286.2 |
mg/dl |
7.2 |
27.89 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11461 |
85 |
| F344/DuCrlCrlj |
plasma glucose level |
fasting (for 16 hours) then glucose solution, 2.8M (2 g/kg) |
Moralejo DH, et al., Proc Assoc Am Physicians 1998 Nov-Dec;110(6):545-58 |
blood glucose amount |
male |
210.0 days
| 7 |
|
128.0 |
mg/dl |
2.4 |
6.35 |
oral glucose tolerance test |
tail |
|
glucose challenge by gastric gavage |
120 |
min |
Glucose-B Test Kit (Wako Pure Chemical Industries, Ltd., Osaka, Japan) |
|
13205 |
228 |
| F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65.0 days
| 15 |
|
0.0 |
mg/dl |
0.0 |
0.0 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
|
min |
|
|
67623 |
85 |
| F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65.0 days
| 15 |
|
0.07 |
mg/dl |
0.01 |
0.04 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
67625 |
85 |
| F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95.0 days
| 15 |
|
0.01 |
mg/dl |
0.0 |
0.01 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
|
min |
|
|
67632 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95.0 days
| 20 |
|
248.4 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
67649 |
85 |
| F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95.0 days
| 20 |
|
0.0 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
|
min |
|
|
67656 |
85 |
| F344/DuCrlCrlj |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
70.0 days
| 6 |
|
218.4 |
g |
3.72 |
9.1 |
whole body digital scale |
|
|
|
|
|
|
|
70683 |
21 |
| F344/DuCrlCrlj |
post-insult time to onset of T-cell lymphoma |
controlled N-propyl-N-nitrosourea content drinking water (400 mg/l) (for 50 days) |
Lu LM, et al., Br J Cancer 1999 May;80(5-6):855-61. |
leukocyte integrity trait |
not specified |
40.0 days-365.0 days |
29 |
|
106.6 |
d |
2.9 |
15.6 |
fluorescence-activated cell sorting method |
|
0.0 |
|
|
|
|
|
70037 |
1280 |
| F344/DuCrlCrlj |
brain wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70.0 days
| 6 |
|
1.86 |
g |
0.02 |
0.04 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71569 |
41 |
| F344/DuCrlCrlj |
heart wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70.0 days
| 6 |
|
0.72 |
g |
0.01 |
0.03 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71571 |
41 |
| F344/DuCrlCrlj |
spleen wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70.0 days
| 6 |
|
0.44 |
g |
0.01 |
0.03 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71581 |
41 |
| F344/DuCrlCrlj |
hematocrit |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70.0 days
| 6 |
|
56.2 |
% |
0.49 |
1.2 |
automated cell/particle size/count analysis method |
|
|
|
|
|
Sysmex, F-800 type |
|
76879 |
1498 |
| F344/DuCrlCrlj |
mean corpuscular hemoglobin |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70.0 days
| 6 |
|
18.0 |
pg |
0.04 |
0.1 |
automated cell/particle size/count analysis method |
|
|
|
|
|
Sysmex, F-800 type |
|
76881 |
1498 |
| F344/DuCrlCrlj |
activated partial thromboplastin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70.0 days
| 6 |
|
14.4 |
s |
1.06 |
2.6 |
automated coagulometer method |
|
|
|
|
|
Sysmex, CA-3000 type |
|
76886 |
1498 |
| F344/DuCrlCrlj |
blood eosinophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
eosinophil quantity |
male |
70.0 days
| 6 |
|
1.0 |
% |
0.41 |
1.0 |
automated differential white blood cell count test |
|
|
|
|
|
May-Giemsa staining |
|
76907 |
1498 |
| F344/DuCrlCrlj |
non-specified leukocyte count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70.0 days
| 6 |
|
0.0 |
% |
0.0 |
0.0 |
automated differential white blood cell count test |
|
|
|
|
|
May-Giemsa staining |
unidentified differential wbc |
76912 |
1498 |
| F344/DuCrlCrlj |
timed urine volume |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63.0 days
| 6 |
|
16.68 |
ml/d |
1.03 |
2.52 |
metabolic cage urine volume measurement method |
|
|
|
|
|
|
|
94868 |
1662 |
| F344/DuCrlCrlj |
urine sodium excretion rate to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63.0 days
| 6 |
|
0.01 |
uEq/min/g |
0.0 |
0.0 |
automated urine analysis |
|
|
|
|
|
Analytical intruments, PVA alpha II |
|
94871 |
1662 |
| F344/DuCrlCrlj |
systolic blood pressure |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
arterial blood pressure trait |
male |
56.0 days-70.0 days |
6 |
serial mean |
140.0 |
mmHg |
4.9 |
12.0 |
tail cuff photoplethysmography |
|
|
|
|
|
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
74937 |
14 |
| F344/DuCrlCrlj |
heart rate |
specific pathogen-free condition |
NBRP Blood Pressure and Heart Rate data |
heart pumping trait |
male |
56.0 days-70.0 days |
6 |
serial mean |
426.0 |
beats/min |
14.7 |
36.0 |
tail cuff photoplethysmography |
|
|
|
|
|
NP-NIBP Monitor MK-2000, Muromachi Kikai Co., Ltd, Japan |
|
74938 |
14 |
| F344/DuCrlCrlj |
plasma glucose level |
fasting (for 16 hours) then glucose solution |
Hirashima T, et al., Diabetes Res Clin Pract 1995 Feb;27(2):91-6. |
blood glucose amount |
male |
210.0 days
| 7 |
|
128.0 |
mg/dl |
2.27 |
6.0 |
oral glucose tolerance test |
|
0.0 |
oral dose |
120 |
min |
|
|
67279 |
729 |
| F344/DuCrlCrlj |
blood glucose level |
partial pancreatectomy (70 %) |
Ogino GenetRes 73:29 '99 |
blood glucose amount |
male |
63.0 days
| 9 |
|
109.9 |
mg/dl |
1.6 |
4.8 |
blood glucose test strip read by electrochemical glucometer |
tail |
0.0 |
post pancreatectomy |
21 |
days |
Toecho Super, Kyoto Daiichi Kagaku, Kyoto, Japan |
converted from mg/dl |
11417 |
84 |
| F344/DuCrlCrlj |
blood glucose level |
partial pancreatectomy (70 %) |
Ogino GenetRes 73:29 '99 |
blood glucose amount |
male |
56.0 days
| 9 |
|
120.1 |
mg/dl |
5.9 |
17.7 |
blood glucose test strip read by electrochemical glucometer |
tail |
0.0 |
post pancreatectomy |
14 |
days |
Toecho Super, Kyoto Daiichi Kagaku, Kyoto, Japan |
converted from mg/dl |
11418 |
84 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65.0 days
| 15 |
|
86.4 |
mg/dl |
3.6 |
13.94 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11451 |
85 |
| F344/DuCrlCrlj |
body weight |
control condition (for 65 days) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
body mass |
male |
65.0 days
| 15 |
|
207.0 |
g |
3.0 |
11.62 |
body weighing method |
|
0.0 |
|
|
|
|
|
11465 |
85 |
| F344/DuCrlCrlj |
serum triglyceride level |
fasting (between 6 and 7 hours) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood triglyceride amount |
male |
185.0 days
| 9 |
|
203.54 |
mg/dl |
7.96 |
23.89 |
serum triglyceride analysis |
tail vein |
|
|
|
|
Vitros TRIG slides (Johnson & Johnson, Rochester, NY) |
|
11476 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
185.0 days
| 9 |
|
102.6 |
mg/dl |
1.8 |
5.4 |
blood glucose analysis |
tail vein |
|
|
|
|
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11479 |
85 |
| F344/DuCrlCrlj |
epididymal fat pad weight |
control condition |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
epididymal fat pad mass |
male |
185.0 days
| 9 |
|
10.5 |
g |
0.7 |
2.1 |
post excision weight measurement |
|
|
|
|
|
|
|
11483 |
85 |
| F344/DuCrlCrlj |
plasma glucose level |
fasting (for 16 hours) then glucose solution, 2.8M (2 g/kg) |
Moralejo DH, et al., Proc Assoc Am Physicians 1998 Nov-Dec;110(6):545-58 |
blood glucose amount |
male |
210.0 days
| 7 |
|
130.9 |
mg/dl |
2.9 |
7.67 |
oral glucose tolerance test |
tail |
|
glucose challenge by gastric gavage |
60 |
min |
Glucose-B Test Kit (Wako Pure Chemical Industries, Ltd., Osaka, Japan) |
|
13203 |
228 |
| F344/DuCrlCrlj |
plasma glucose level |
fasting (for 16 hours) then glucose solution, 2.8M (2 g/kg) |
Moralejo DH, et al., Proc Assoc Am Physicians 1998 Nov-Dec;110(6):545-58 |
blood glucose amount |
male |
210.0 days
| 7 |
|
139.0 |
mg/dl |
2.4 |
6.35 |
oral glucose tolerance test |
tail |
|
glucose challenge by gastric gavage |
90 |
min |
Glucose-B Test Kit (Wako Pure Chemical Industries, Ltd., Osaka, Japan) |
|
13204 |
228 |
| F344/DuCrlCrlj |
body weight |
control condition |
Muramatsu Y, et al., Biochem Biophys Res Commun 2005 Jun 17;331(4):1270-6. |
body mass |
male |
245.0 days
| 12 |
|
393.6 |
g |
5.31 |
18.4 |
body weighing method |
|
|
|
|
|
|
|
12431 |
262 |
| F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95.0 days
| 15 |
|
0.08 |
mg/dl |
0.01 |
0.05 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
67634 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95.0 days
| 20 |
|
334.8 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
67648 |
85 |
| F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95.0 days
| 20 |
|
0.01 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
15 |
min |
|
|
67657 |
85 |
| F344/DuCrlCrlj |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
35.0 days
| 6 |
|
90.6 |
g |
0.78 |
1.9 |
whole body digital scale |
|
|
|
|
|
|
|
70684 |
21 |
| F344/DuCrlCrlj |
plasma free fatty acids level |
fasting (for 16 hours) |
Yamasaki Y, et al., Clin Exp Pharmacol Physiol 2000 Nov;27(11):881-6. |
blood free fatty acid amount |
male |
112.0 days
| 15 |
|
0.65 |
mmol/l |
0.03 |
0.11 |
automated blood analysis |
|
0.0 |
|
|
|
|
"mEq/l" can not be converted to CMO:0000546's standard unit: "mmol/l" |
68969 |
1035 |
| F344/DuCrlCrlj |
mean corpuscular volume |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte size trait |
male |
70.0 days
| 6 |
|
57.7 |
fl |
0.65 |
1.6 |
automated cell/particle size/count analysis method |
|
|
|
|
|
Sysmex, F-800 type |
|
76880 |
1498 |
| F344/DuCrlCrlj |
platelet count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
platelet quantity |
male |
70.0 days
| 6 |
|
875.0 |
x 1000 /ul |
20.82 |
51.0 |
automated cell/particle size/count analysis method |
|
|
|
|
|
Sysmex, F-800 type |
|
76884 |
1498 |
| F344/DuCrlCrlj |
plasma albumin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70.0 days
| 6 |
|
0.36 |
g/l |
0.0 |
0.01 |
automated plasma albumin analysis |
|
|
|
|
|
Hitachi, model 7170 |
|
76891 |
1498 |
| F344/DuCrlCrlj |
plasma high density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood HDL cholesterol amount |
male |
70.0 days
| 6 |
|
29.7 |
mg/dl |
0.9 |
2.2 |
automated plasma analysis |
|
|
|
|
|
PMID:15591307 |
|
76895 |
1498 |
| F344/DuCrlCrlj |
plasma creatinine level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood creatinine amount |
male |
70.0 days
| 6 |
|
0.26 |
mg/dl |
0.0 |
0.01 |
automated plasma creatinine analysis |
|
|
|
|
|
Hitachi, model 7170 |
|
76900 |
1498 |
| F344/DuCrlCrlj |
plasma potassium level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood potassium amount |
male |
70.0 days
| 6 |
|
4.03 |
mmol/l |
0.04 |
0.09 |
automated blood electrolyte analysis |
|
|
|
|
|
Analytical intruments, PVA alpha II |
|
76904 |
1498 |
| F344/DuCrlCrlj |
blood basophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
basophil quantity |
male |
70.0 days
| 6 |
|
0.0 |
% |
0.41 |
1.0 |
automated differential white blood cell count test |
|
|
|
|
|
May-Giemsa staining |
|
76906 |
1498 |
| F344/DuCrlCrlj |
blood segmented neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70.0 days
| 6 |
|
12.0 |
% |
2.04 |
5.0 |
automated differential white blood cell count test |
|
|
|
|
|
May-Giemsa staining |
segmented neutrophil % |
76909 |
1498 |
| F344/DuCrlCrlj |
brain weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
brain mass |
male |
70.0 days
| 6 |
|
0.91 |
% |
0.01 |
0.03 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71570 |
41 |
| F344/DuCrlCrlj |
liver weight as percentage of body weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70.0 days
| 6 |
|
2.82 |
% |
0.02 |
0.05 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71576 |
41 |
| F344/DuCrlCrlj |
urine sodium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine sodium amount |
male |
63.0 days
| 6 |
|
119.6 |
mmol/l |
11.96 |
29.3 |
automated urine analysis |
|
|
|
|
|
Analytical intruments, PVA alpha II |
|
94870 |
1662 |
| F344/DuCrlCrlj |
body weight |
control condition |
Ogino Genom 2000 Nov 15;70(1):19-25. |
body mass |
male |
245.0 days-252.0 days |
15 |
|
404.4 |
g |
5.16 |
20.0 |
body weighing method |
|
|
|
|
|
|
|
11411 |
83 |
| F344/DuCrlCrlj |
epididymal fat pad weight |
control condition |
Ogino Genom 2000 Nov 15;70(1):19-25. |
epididymal fat pad mass |
male |
252.0 days
| 15 |
|
11.2 |
g |
0.31 |
1.2 |
post excision weight measurement |
|
0.0 |
|
|
|
|
|
11415 |
83 |
| F344/DuCrlCrlj |
body weight |
control condition (for 95 days) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
body mass |
male |
95.0 days
| 15 |
|
279.0 |
g |
4.0 |
15.49 |
body weighing method |
|
0.0 |
|
|
|
|
|
11444 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95.0 days
| 15 |
|
109.8 |
mg/dl |
3.6 |
13.94 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11431 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65.0 days
| 15 |
|
86.4 |
mg/dl |
1.8 |
6.97 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
|
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11450 |
85 |
| F344/DuCrlCrlj |
serum total cholesterol level |
fasting (between 6 and 7 hours) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood cholesterol amount |
male |
185.0 days
| 9 |
|
81.85 |
mg/dl |
1.93 |
5.79 |
serum total cholesterol measurement test |
tail vein |
|
|
|
|
Vitros CHOL slides (Johnson & Johnson, Rochester, NY) |
|
11473 |
85 |
| F344/DuCrlCrlj |
serum high density lipoprotein cholesterol level |
fasting (between 6 and 7 hours) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood HDL cholesterol amount |
male |
185.0 days
| 9 |
|
37.07 |
mg/dl |
0.77 |
2.32 |
serum high-density lipoprotein-cholesterol measurement test |
tail vein |
|
|
|
|
N-geneous HDL-c kit (Biomed-RK, Jonkoping, Sweden) |
|
11470 |
85 |
| F344/DuCrlCrlj |
body weight |
fasting (for 16 hours) |
Moralejo DH, et al., Proc Assoc Am Physicians 1998 Nov-Dec;110(6):545-58 |
body mass |
male |
210.0 days
| 10 |
|
374.1 |
g |
8.0 |
25.3 |
body weighing method |
|
|
|
|
|
|
|
11968 |
228 |
| F344/DuCrlCrlj |
mesenteric fat pad weight |
control condition |
Muramatsu Y, et al., Biochem Biophys Res Commun 2005 Jun 17;331(4):1270-6. |
mesenteric fat pad mass |
male |
245.0 days
| 12 |
|
11.5 |
g |
0.23 |
0.8 |
post excision weight measurement |
|
|
|
|
|
|
|
12433 |
262 |
| F344/DuCrlCrlj |
epididymal fat pad weight |
control condition |
Muramatsu Y, et al., Biochem Biophys Res Commun 2005 Jun 17;331(4):1270-6. |
epididymal fat pad mass |
male |
245.0 days
| 12 |
|
11.2 |
g |
0.26 |
0.9 |
post excision weight measurement |
|
|
|
|
|
|
|
12435 |
262 |
| F344/DuCrlCrlj |
plasma glucose level |
fasting (for 16 hours) |
Yamasaki Y, et al., Clin Exp Pharmacol Physiol 2000 Nov;27(11):881-6. |
blood glucose amount |
male |
112.0 days
| 15 |
|
126.0 |
mg/dl |
5.4 |
20.91 |
plasma glucose analysis |
|
0.0 |
|
|
|
|
|
68962 |
1035 |
| F344/DuCrlCrlj |
plasma triglyceride level |
fasting (for 16 hours) |
Yamasaki Y, et al., Clin Exp Pharmacol Physiol 2000 Nov;27(11):881-6. |
blood triglyceride amount |
male |
112.0 days
| 15 |
|
0.55 |
mmol/l |
0.03 |
0.13 |
automated blood analysis |
|
0.0 |
|
|
|
|
|
68964 |
1035 |
| F344/DuCrlCrlj |
abdominal fat pad weight |
fasting (for 16 hours) |
Yamasaki Y, et al., Clin Exp Pharmacol Physiol 2000 Nov;27(11):881-6. |
abdominal fat pad mass |
male |
112.0 days
| 15 |
|
8.13 |
g |
0.17 |
0.66 |
post excision weight measurement |
|
0.0 |
|
|
|
|
|
68973 |
1035 |
| F344/DuCrlCrlj |
pancreas weight to body weight ratio |
partial pancreatectomy |
Moralejo DH, et al., Mamm Genome 1998 Oct;9(10):794-8. |
pancreas mass |
male |
70.0 days
| 9 |
|
0.89 |
mg/g |
0.03 |
0.09 |
post excision weight measurement |
|
0.0 |
partial pancreatectomy |
28 |
days |
|
|
68240 |
911 |
| F344/DuCrlCrlj |
percentage of study population developing T-cell lymphomas during a period of time |
controlled N-propyl-N-nitrosourea content drinking water (400 mg/l) (for 50 days) |
Lu LM, et al., Br J Cancer 1999 May;80(5-6):855-61. |
leukocyte integrity trait |
not specified |
40.0 days-365.0 days |
29 |
|
96.6 |
% |
|
|
fluorescence-activated cell sorting method |
|
0.0 |
|
|
|
|
|
70014 |
1280 |
| F344/DuCrlCrlj |
percentage of study population developing leukemia during a period of time |
controlled N-propyl-N-nitrosourea content drinking water (400 mg/l) (for 50 days) |
Lu LM, et al., Br J Cancer 1999 May;80(5-6):855-61. |
leukocyte integrity trait |
not specified |
40.0 days-365.0 days |
29 |
|
0.0 |
% |
|
|
ex vivo light microscopy with immunohistochemistry |
|
0.0 |
|
|
|
light microscopy with immuno |
|
70060 |
1280 |
| F344/DuCrlCrlj |
lung weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70.0 days
| 6 |
|
0.38 |
% |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71574 |
41 |
| F344/DuCrlCrlj |
liver wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
liver mass |
male |
70.0 days
| 6 |
|
5.79 |
g |
0.12 |
0.3 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71575 |
41 |
| F344/DuCrlCrlj |
both kidneys wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
kidney mass |
male |
70.0 days
| 6 |
|
1.25 |
g |
0.02 |
0.05 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71577 |
41 |
| F344/DuCrlCrlj |
both adrenal glands weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70.0 days
| 6 |
|
17.5 |
mg/100g |
1.92 |
4.7 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71580 |
41 |
| F344/DuCrlCrlj |
both adrenal glands wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
adrenal gland mass |
male |
70.0 days
| 6 |
|
36.0 |
mg |
4.04 |
9.9 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71579 |
41 |
| F344/DuCrlCrlj |
spleen weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
spleen mass |
male |
70.0 days
| 6 |
|
0.22 |
% |
0.01 |
0.02 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71582 |
41 |
| F344/DuCrlCrlj |
both testes wet weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70.0 days
| 6 |
|
1.35 |
% |
0.03 |
0.08 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71584 |
41 |
| F344/DuCrlCrlj |
both testes wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
testis mass |
male |
70.0 days
| 6 |
|
2.78 |
g |
0.1 |
0.25 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71583 |
41 |
| F344/DuCrlCrlj |
prothrombin time |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood coagulation trait |
male |
70.0 days
| 6 |
|
15.4 |
s |
0.16 |
0.4 |
automated coagulometer method |
|
|
|
|
|
Sysmex, CA-3000 type |
|
76885 |
1498 |
| F344/DuCrlCrlj |
plasma aspartate aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood aspartate transaminase amount |
male |
70.0 days
| 6 |
|
62.0 |
U/l |
1.63 |
4.0 |
automated plasma analysis |
|
|
|
|
|
PMID:15591307 |
|
76887 |
1498 |
| F344/DuCrlCrlj |
plasma alanine aminotransferase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alanine transaminase amount |
male |
70.0 days
| 6 |
|
35.0 |
U/l |
1.22 |
3.0 |
automated plasma analysis |
|
|
|
|
|
PMID:15591307 |
|
76888 |
1498 |
| F344/DuCrlCrlj |
plasma glucose level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood glucose amount |
male |
70.0 days
| 6 |
|
155.0 |
mg/dl |
6.53 |
16.0 |
automated plasma analysis |
|
|
|
|
|
PMID:15591307 |
|
76893 |
1498 |
| F344/DuCrlCrlj |
plasma total bilirubin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood bilirubin amount |
male |
70.0 days
| 6 |
|
0.0 |
mg/dl |
0.0 |
0.0 |
automated plasma analysis |
|
|
|
|
|
PMID:15591307 |
total plasma bilirubin level |
76898 |
1498 |
| F344/DuCrlCrlj |
plasma chloride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood chloride amount |
male |
70.0 days
| 6 |
|
105.0 |
mmol/l |
0.41 |
1.0 |
automated blood electrolyte analysis |
|
|
|
|
|
Analytical intruments, PVA alpha II |
|
76905 |
1498 |
| F344/DuCrlCrlj |
urine potassium level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine potassium amount |
male |
63.0 days
| 6 |
|
75.2 |
mmol/l |
6.25 |
15.3 |
automated urine analysis |
|
|
|
|
|
Analytical intruments, PVA alpha II |
|
94872 |
1662 |
| F344/DuCrlCrlj |
body temperature |
specific pathogen-free condition |
NBRP Body Temperature data |
body temperature trait |
male |
56.0 days-70.0 days |
6 |
serial mean |
37.8 |
degrees C |
0.16 |
0.4 |
digital rectal thermometry |
|
|
|
|
|
|
|
74939 |
22 |
| F344/DuCrlCrlj |
plasma glucose level |
fasting (for 12 hours) then glucose solution, 2.8M (2 g/kg) |
Ogino Genom 2000 Nov 15;70(1):19-25. |
blood glucose amount |
male |
245.0 days
| 15 |
|
92.6 |
mg/dl |
1.65 |
6.4 |
oral glucose tolerance test |
tail vein |
0 |
gastric gavage |
30 |
min |
|
converted from mg/dl |
11405 |
83 |
| F344/DuCrlCrlj |
retroperitoneal fat pad weight |
control condition |
Ogino Genom 2000 Nov 15;70(1):19-25. |
retroperitoneal fat pad mass |
male |
252.0 days
| 15 |
|
10.7 |
g |
0.23 |
0.9 |
post excision weight measurement |
|
0.0 |
|
|
|
|
|
11414 |
83 |
| F344/DuCrlCrlj |
blood glucose level |
partial pancreatectomy (70 %) |
Ogino GenetRes 73:29 '99 |
blood glucose amount |
male |
70.0 days
| 9 |
|
117.8 |
mg/dl |
2.7 |
8.1 |
blood glucose test strip read by electrochemical glucometer |
tail |
0.0 |
post pancreatectomy |
28 |
days |
Toecho Super, Kyoto Daiichi Kagaku, Kyoto, Japan |
converted from mg/dl |
11416 |
84 |
| F344/DuCrlCrlj |
blood glucose level |
control condition |
Ogino GenetRes 73:29 '99 |
blood glucose amount |
male |
42.0 days
| 9 |
|
102.6 |
mg/dl |
2.2 |
6.6 |
blood glucose test strip read by electrochemical glucometer |
tail |
0.0 |
|
|
|
Toecho Super, Kyoto Daiichi Kagaku, Kyoto, Japan |
converted from mg/dl |
11426 |
84 |
| F344/DuCrlCrlj |
blood glucose level |
partial pancreatectomy (70 %) |
Ogino GenetRes 73:29 '99 |
blood glucose amount |
male |
45.0 days
| 9 |
|
115.8 |
mg/dl |
3.4 |
10.2 |
blood glucose test strip read by electrochemical glucometer |
tail |
0.0 |
post pancreatectomy |
3 |
days |
Toecho Super, Kyoto Daiichi Kagaku, Kyoto, Japan |
converted from mg/dl |
11427 |
84 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95.0 days
| 15 |
|
135.0 |
mg/dl |
5.4 |
20.91 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
60 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11434 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95.0 days
| 15 |
|
219.6 |
mg/dl |
5.4 |
20.91 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
30 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11437 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95.0 days
| 15 |
|
271.8 |
mg/dl |
9.0 |
34.86 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
15 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11440 |
85 |
| F344/DuCrlCrlj |
blood glucose level area under curve (AUC) |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95.0 days
| 15 |
|
15545.45 |
(mg/dl) x min |
381.82 |
1478.78 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11446 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65.0 days
| 15 |
|
88.2 |
mg/dl |
3.6 |
13.94 |
intraperitoneal glucose tolerance test |
tail vein |
|
post glucose injection |
60 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11454 |
85 |
| F344/DuCrlCrlj |
blood glucose level area under curve (AUC) |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
65.0 days
| 15 |
|
12818.18 |
(mg/dl) x min |
218.18 |
845.01 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
90 |
min |
Reflolux II; BM-test Glycemie I-44 reagent strips (Boeringer-Mannheim, Germany) |
|
11467 |
85 |
| F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
65.0 days
| 15 |
|
0.03 |
mg/dl |
0.0 |
0.02 |
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
67628 |
85 |
| F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
185.0 days
| 9 |
|
0.02 |
mg/dl |
0.0 |
0.01 |
enzyme linked immunosorbent assay |
tail vein |
0.0 |
|
|
|
|
|
67644 |
85 |
| F344/DuCrlCrlj |
blood glucose level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood glucose amount |
male |
95.0 days
| 20 |
|
111.6 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
90 |
min |
|
|
67651 |
85 |
| F344/DuCrlCrlj |
serum insulin level |
fasting (between 6 and 7 hours) then glucose solution (2 g/kg) |
Galli J, et al., Diabetes 1999 Dec;48(12):2463-70. |
blood insulin amount |
male |
95.0 days
| 20 |
|
0.01 |
mg/dl |
|
|
intraperitoneal glucose tolerance test |
tail vein |
0.0 |
post glucose injection |
30 |
min |
|
|
67658 |
85 |
| F344/DuCrlCrlj |
red blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
erythrocyte quantity |
male |
70.0 days
| 6 |
|
9.75 |
x 10E6 cells/ul |
0.09 |
0.21 |
automated cell/particle size/count analysis method |
|
|
|
|
|
Sysmex, F-800 type |
|
76877 |
1498 |
| F344/DuCrlCrlj |
blood hemoglobin level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood hemoglobin amount |
male |
70.0 days
| 6 |
|
17.5 |
g/dl |
0.16 |
0.4 |
automated cell/particle size/count analysis method |
|
|
|
|
|
Sysmex, F-800 type |
|
76878 |
1498 |
| F344/DuCrlCrlj |
white blood cell count |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
leukocyte quantity |
male |
70.0 days
| 6 |
|
6.1 |
x 1000 cells/ul |
0.33 |
0.8 |
automated cell/particle size/count analysis method |
|
|
|
|
|
Sysmex, F-800 type |
|
76883 |
1498 |
| F344/DuCrlCrlj |
plasma alkaline phosphatase activity level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood alkaline phosphatase amount |
male |
70.0 days
| 6 |
|
504.0 |
IU/l |
13.47 |
33.0 |
automated plasma analysis |
|
|
|
|
|
PMID:15591307 |
|
76889 |
1498 |
| F344/DuCrlCrlj |
plasma albumin to plasma total protein ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood albumin amount |
male |
70.0 days
| 6 |
|
1.6 |
null |
0.02 |
0.05 |
automated plasma protein analysis |
|
|
|
|
|
Hitachi, model 7170 |
plasma albumin to plasma total protein ratio |
76892 |
1498 |
| F344/DuCrlCrlj |
plasma low density lipoprotein cholesterol level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood LDL cholesterol amount |
male |
70.0 days
| 6 |
|
3.0 |
mg/dl |
0.41 |
1.0 |
automated plasma analysis |
|
|
|
|
|
PMID:15591307 |
|
76896 |
1498 |
| F344/DuCrlCrlj |
plasma triglyceride level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood triglyceride amount |
male |
70.0 days
| 6 |
|
0.93 |
mmol/l |
0.05 |
0.12 |
automated plasma analysis |
|
|
|
|
|
PMID:15591307 |
|
76897 |
1498 |
| F344/DuCrlCrlj |
plasma phosphate level |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
blood phosphate amount |
male |
70.0 days
| 6 |
|
7.1 |
mg/dl |
0.08 |
0.2 |
automated blood electrolyte analysis |
|
|
|
|
|
Hitachi, model 7170 |
|
76901 |
1498 |
| F344/DuCrlCrlj |
blood band neutrophil count to total leukocyte count ratio |
fasting (for 16 hours) |
NBRP Hematology & Blood Biochemistry data |
neutrophil quantity |
male |
70.0 days
| 6 |
|
1.0 |
% |
0.41 |
1.0 |
automated differential white blood cell count test |
|
|
|
|
|
May-Giemsa staining |
band neutrophil % |
76908 |
1498 |
| F344/DuCrlCrlj |
timed urine volume to body weight ratio |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine output |
male |
63.0 days
| 6 |
|
0.05 |
ul/min/g |
0.0 |
0.01 |
metabolic cage urine volume measurement method |
|
|
|
|
|
|
|
94869 |
1662 |
| F344/DuCrlCrlj |
urine chloride level |
0.9% sodium chloride solution (25 ml/kg) |
NBRP Urine Volume and Urine Electrolyte data |
urine chloride amount |
male |
63.0 days
| 6 |
|
144.0 |
mEq/L |
13.06 |
32.0 |
automated urine analysis |
|
|
|
|
|
|
|
94874 |
1662 |
| F344/DuCrlCrlj |
body weight |
specific pathogen-free condition |
NBRP Body Weight data |
body mass |
male |
42.0 days
| 6 |
|
117.9 |
g |
1.51 |
3.7 |
whole body digital scale |
|
|
|
|
|
|
|
70685 |
21 |
| F344/DuCrlCrlj |
plasma total cholesterol level |
fasting (for 16 hours) |
Yamasaki Y, et al., Clin Exp Pharmacol Physiol 2000 Nov;27(11):881-6. |
blood cholesterol amount |
male |
112.0 days
| 15 |
|
38.61 |
mg/dl |
1.54 |
5.98 |
automated blood analysis |
|
0.0 |
|
|
|
|
|
68967 |
1035 |
| F344/DuCrlCrlj |
serum leptin level |
fasting (for 16 hours) |
Yamasaki Y, et al., Clin Exp Pharmacol Physiol 2000 Nov;27(11):881-6. |
blood leptin amount |
male |
112.0 days
| 15 |
|
16.32 |
ng/ml |
0.93 |
3.6 |
enzyme linked immunosorbent assay |
|
0.0 |
|
|
|
|
|
68971 |
1035 |
| F344/DuCrlCrlj |
pancreas wet weight |
partial pancreatectomy |
Moralejo DH, et al., Mamm Genome 1998 Oct;9(10):794-8. |
pancreas mass |
male |
70.0 days
| 9 |
|
0.2 |
g |
0.01 |
0.02 |
post excision weight measurement |
|
0.0 |
partial pancreatectomy |
28 |
days |
|
|
68238 |
911 |
| F344/DuCrlCrlj |
lung wet weight |
specific pathogen-free condition |
NBRP Organ Weight data |
lung mass |
male |
70.0 days
| 6 |
|
0.78 |
g |
0.02 |
0.04 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71573 |
41 |
| F344/DuCrlCrlj |
heart weight to body weight ratio |
specific pathogen-free condition |
NBRP Organ Weight data |
heart mass |
male |
70.0 days
| 6 |
|
3.49 |
g/kg |
0.04 |
0.09 |
Shimadzu electronic balance post excision weight measurement |
|
|
|
|
|
|
|
71572 |
41 |