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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:serum high density lipoprotein cholesterol level
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Accession:CMO:0000361 term browser browse the term
Definition:Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in high-density lipoprotein (HDL) molecules in a specified volume of serum, the clear liquid that separates from blood after it has clotted completely, i.e. blood plasma from which fibrinogen has been removed. HDL is the smallest of the major lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The HDL class of lipoproteins, specifically the subtypes of HDL2 and HDL3, have densities between 1.063 and 1.210 g/ml.
Comment:Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided.
Synonyms:related_synonym: serum HDL level;   serum HDL-C level


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serum high density lipoprotein cholesterol level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Scl12 Serum cholesterol level QTL 12 IDA RGD PMID:8698878 RGD:61079 NCBI chr19:13,926,401...30,303,727 JBrowse link
Q Scl27 Serum cholesterol level QTL 27 IDA RGD PMID:11721057 RGD:70849 NCBI chr18:52,292,875...59,796,643 JBrowse link
Q Scl28 Serum cholesterol level QTL 28 IDA RGD PMID:11721057 RGD:70849 NCBI chr18:11,944,299...24,797,117 JBrowse link
Q Scl61 Serum cholesterol level QTL 61 IDA RGD PMID:10720472 RGD:619689 NCBI chr17:27,389,946...53,481,766 JBrowse link

Related Phenotype Data for Term "serum high density lipoprotein cholesterol level" (CMO:0000361)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:
Term paths to the root
Path 1
Term Annotations click to browse term
  clinical measurement 2369
    blood measurement 443
      blood chemistry measurement 426
        blood lipid measurement 109
          serum lipid level 31
            serum sterol level 28
              serum cholesterol level 28
                serum high density lipoprotein cholesterol level 4
                  calculated serum high density lipoprotein cholesterol level + 0
                  serum high density lipoprotein cholesterol to low density lipoprotein cholesterol ratio 0
                  serum low density lipoprotein cholesterol to high density lipoprotein cholesterol ratio 0
Path 2
Term Annotations click to browse term
  clinical measurement 2369
    blood measurement 443
      blood chemistry measurement 426
        blood lipid measurement 109
          blood sterol level 64
            blood cholesterol level 64
              blood lipoprotein cholesterol level 19
                blood high density lipoprotein cholesterol level 7
                  serum high density lipoprotein cholesterol level 4
                    calculated serum high density lipoprotein cholesterol level + 0
                    serum high density lipoprotein cholesterol to low density lipoprotein cholesterol ratio 0
                    serum low density lipoprotein cholesterol to high density lipoprotein cholesterol ratio 0
paths to the root