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CLINICAL MEASUREMENT - ANNOTATIONS

The Clinical Measurement Ontology (CMO), Measurement Methods Ontology (MMO), and Experimental Condition Ontology (XCO) are currently being developed at the Rat Genome Database. For more information about these vocabularies please see Shimoyama et al. Three ontologies to define phenotype measurement data. Front Genet. 2012;3:87. Epub 2012 May 28 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:plasma low density lipoprotein cholesterol level
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Accession:CMO:0000647 term browser browse the term
Definition:Measurement of the amount of cholesterol, a eukaryotic sterol that in higher animals is the precursor of bile acids and steroid hormones and a key constituent of cell membranes, carried in low-density lipoprotein (LDL) molecules in a specified volume of plasma, the fibrinogen-containing fluid portion of the blood in which the particulate components are suspended. LDL constitute a class of relatively large, heterogeneous lipoprotein particles, complex molecules that consist of a protein membrane surrounding a core of lipids. The LDL class of lipoproteins has a density between 1.019 and 1.063 g/ml. In some animal species, such as canine and rodents, this may overlap with the HDL1 class and be designated LDL/HDL1.
Comment:Values for density ranges of the lipoprotein classes are approximate. The classes may be defined differently by different researchers, in part because class definitions depend on the number of subclasses into which the lipoprotein fractions are divided.
Synonyms:related_synonym: plasma LDL level;   plasma LDL-C level


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calculated plasma low density lipoprotein cholesterol level term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
Q Scl18 Serum cholesterol level QTL 18 IDA RGD PMID:14739155 RGD:737694 NCBI chr 5:79,584,860...124,584,860 JBrowse link

Related Phenotype Data for Term "plasma low density lipoprotein cholesterol level" (CMO:0000647)

Rat Strains:
Clinical Measurements:
Experimental Conditions:
Measurement Methods:
Term paths to the root
Path 1
Term Annotations click to browse term
  clinical measurement 2369
    blood measurement 443
      blood chemistry measurement 426
        blood lipid measurement 109
          plasma lipid level 19
            plasma sterol level 19
              plasma cholesterol level 19
                plasma low density lipoprotein cholesterol level 1
                  calculated plasma low density lipoprotein cholesterol level + 1
Path 2
Term Annotations click to browse term
  clinical measurement 2369
    blood measurement 443
      blood chemistry measurement 426
        blood lipid measurement 109
          blood sterol level 64
            blood cholesterol level 64
              blood lipoprotein cholesterol level 19
                blood low density lipoprotein cholesterol level 11
                  plasma low density lipoprotein cholesterol level 1
                    calculated plasma low density lipoprotein cholesterol level + 1
paths to the root