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CROSS-SPECIES ANATOMY - ANNOTATIONS

The Basic subset of the UBERON integrated, cross-species anatomy ontology is downloaded weekly from http://berkeleybop.org/ontologies/uberon/basic.obo. For more information about this ontology see the "About" page on the UBERON website at http://uberon.github.io/about.html.
Term:distal segment of digit
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Accession:UBERON:0009551 term browser browse the term
Definition:A segment of a digit containing the distal phalanx, and overlapping the distal interphalangeal joint[CJM]. The digit tip is derived from multiple and distinct embryonic origins, and includes the distal bone with associated marrow cavity and haematopoietic cells, ventral (flexor) and dorsal (extensor) tendons, sweat glands with myoepithelial and luminal secreting cells and associated neurons for innervation, dermis with resident melanocytes and dendritic cells, mesenchyme with resident fibroblasts, skin epidermis with hair follicles, a nail organ composed of six specific parts (the root, nail bed, nail plate, eponychium (cuticle), perionychium and hyponychium).
Comment:[development-note] "Newborn and adult mice are able to regrow forelimb (finger) and hindlimb (toe) digit tips after their amputation through the distal interphalangeal joint. Regeneration of the digit tip involves the integrated regrowth of multiple tissues within 2-3 months, reaching an external morphology that is cosmetically and functionally similar to normal digits. Most importantly, regeneration of the mouse distal digit shares morphological similarities with clinical cases documenting regrowth of missing distal portions of fingers in both children and adults"
Synonyms:exact_synonym: digit tip;   distal digit segment;   tip of digit


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Term paths to the root
Path 1
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          multicellular anatomical structure 0
            organism subdivision 0
              digit plus metapodial segment 0
                digit 0
                  distal segment of digit 0
                    blastema of regenerating digit tip 0
                    distal limb integumentary appendage + 0
                    distal phalanx + 0
                    distal segment of manual digit + 0
                    distal segment of pedal digit + 0
Path 2
Term Annotations click to browse term
  UBERON ontology 0
    anatomical entity 0
      material anatomical entity 0
        anatomical structure 0
          multicellular anatomical structure 0
            multicellular organism 0
              embryo 0
                embryonic structure 0
                  presumptive structure 0
                    paired limb/fin bud 0
                      limb bud 0
                        limb 0
                          limb segment 0
                            autopod region 0
                              segment of autopod 0
                                digitopodium region 0
                                  acropodium region 0
                                    digit 0
                                      distal segment of digit 0
                                        blastema of regenerating digit tip 0
                                        distal limb integumentary appendage + 0
                                        distal phalanx + 0
                                        distal segment of manual digit + 0
                                        distal segment of pedal digit + 0
paths to the root