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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:endocrine system disease pathway
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Accession:PW:0001547 term browser browse the term


show annotations for term's descendants           Sort by:
adrenoleukodystrophy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCD1 ATP binding cassette subfamily D member 1 ISO SMPDB SMP:00516 NCBI chr  X:121,545,690...121,564,117
Ensembl chr  X:121,545,586...121,563,186 		JBrowse link
G ABCD2 ATP binding cassette subfamily D member 2 ISO SMPDB SMP:00516 NCBI chr27:14,015,093...14,084,362
Ensembl chr27:14,015,091...14,163,312 		JBrowse link
G ACSL1 acyl-CoA synthetase long chain family member 1 ISO SMPDB SMP:00516 NCBI chr16:45,735,675...45,806,235
Ensembl chr16:45,735,703...45,804,970 		JBrowse link
G CPT2 carnitine palmitoyltransferase 2 ISO SMPDB SMP:00516 NCBI chr 5:55,718,209...55,786,175
Ensembl chr 5:55,718,510...55,744,809 		JBrowse link
G CRAT carnitine O-acetyltransferase ISO SMPDB SMP:00516 NCBI chr 9:54,566,708...54,580,301
Ensembl chr 9:54,566,407...54,580,025 		JBrowse link
G CROT carnitine O-octanoyltransferase ISO SMPDB SMP:00516 NCBI chr14:13,475,130...13,532,536
Ensembl chr14:13,475,235...13,532,536 		JBrowse link
G PEX11G peroxisomal biogenesis factor 11 gamma ISO SMPDB SMP:00516 NCBI chr20:52,284,674...52,292,922
Ensembl chr20:52,282,762...52,292,888 		JBrowse link
G PEX13 peroxisomal biogenesis factor 13 ISO SMPDB SMP:00516 NCBI chr10:61,113,213...61,130,157
Ensembl chr10:61,123,655...61,193,241 		JBrowse link
G PEX14 peroxisomal biogenesis factor 14 ISO SMPDB SMP:00516 NCBI chr 2:85,224,376...85,362,684
Ensembl chr 2:85,224,365...85,389,069 		JBrowse link
G SLC25A20 solute carrier family 25 member 20 ISO SMPDB SMP:00516 NCBI chr20:40,244,222...40,271,100
Ensembl chr20:40,244,229...40,270,433 		JBrowse link
diabetes mellitus pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO RGD PMID:18025464 RGD:2301904 NCBI chr21:39,963,001...40,037,040
Ensembl chr21:39,962,947...40,036,981 		JBrowse link
G SOD3 superoxide dismutase 3 ISO RGD PMID:12830380 RGD:1581299 NCBI chr 3:85,382,698...85,387,144
Ensembl chr 3:85,382,484...85,387,455 		JBrowse link
diabetic nephropathy pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:16528250 RGD:1581322 NCBI chr32:11,354,070...11,362,325
Ensembl chr32:11,353,953...11,362,069 		JBrowse link
type 1 diabetes mellitus pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase ISO RGD PMID:17940120 RGD:5509611 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119 		JBrowse link
type 2 diabetes mellitus pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 ISO DNA:missense mutation::A1369S RGD PMID:17259403 RGD:2313628 NCBI chr21:39,963,001...40,037,040
Ensembl chr21:39,962,947...40,036,981 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 ISO RGD PMID:15166380 RGD:2313408 NCBI chr 1:113,359,038...113,407,119
Ensembl chr 1:113,359,575...113,407,131 		JBrowse link
G INS insulin ISO RGD PMID:9809695 RGD:2313694 NCBI chr18:46,324,047...46,324,933
Ensembl chr18:46,324,041...46,325,122 		JBrowse link
G INSR insulin receptor ISO RGD PMID:9809695 RGD:2313694 NCBI chr20:52,017,261...52,136,061
Ensembl chr20:52,021,887...52,136,046 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO DNA:missense mutation::p.E23K (human)
polymorphisms in the gene are linked to altered insulin secretion; E23K polymorphism appears to confer susceptibility to diabetes type-2 in Caucasian population		 RGD PMID:15565284 PMID:17259403 RGD:2313610 RGD:2313628 NCBI chr21:39,953,461...39,957,615
Ensembl chr21:39,955,551...39,956,723 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4052
    disease pathway 717
      endocrine system disease pathway 18
        adrenal gland disease pathway + 10
        diabetes mellitus pathway + 8
paths to the root