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bendroflumethiazide pharmacodynamics pathway - Ontology Report - Rat Genome Database

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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (https://rgd.mcw.edu/rgdweb/contact/contactus.html).
Term:bendroflumethiazide pharmacodynamics pathway
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Accession:PW:0002197 term browser browse the term
Definition:The pathway of bendroflumethiazide-target interaction and of the biochemical or physiological responses to drug. The drug reduces sodium reabsorption in the distal convoluted tubule of kidney nephron. Genetic variations can cause differences in the response of the organism to the drug.
Synonyms:related_synonym: SMP:00090

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bendroflumethiazide pharmacodynamics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AQP1 aquaporin 1 ISO SMPDB SMP:00090 NCBI chr14:43,592,266...43,603,903
Ensembl chr14:43,578,721...43,605,720 		JBrowse link
G AQP2 aquaporin 2 ISO SMPDB SMP:00090 NCBI chr27:4,743,127...4,750,907
Ensembl chr27:4,743,127...4,750,907 		JBrowse link
G AQP3 aquaporin 3 ISO SMPDB SMP:00090 NCBI chr11:50,517,509...50,524,565 JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO SMPDB SMP:00090 NCBI chr17:53,828,482...53,847,043
Ensembl chr17:53,813,976...53,847,167 		JBrowse link
G ATP1A3 ATPase Na+/K+ transporting subunit alpha 3 ISO SMPDB SMP:00090 NCBI chr 1:112,325,988...112,346,056
Ensembl chr 1:112,325,289...112,346,916 		JBrowse link
G ATP1A4 ATPase Na+/K+ transporting subunit alpha 4 ISO SMPDB SMP:00090 NCBI chr38:22,023,176...22,080,656
Ensembl chr38:22,023,221...22,080,604 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 ISO SMPDB SMP:00090 NCBI chr 7:29,464,132...29,487,124
Ensembl chr 7:29,464,132...29,487,947 		JBrowse link
G ATP1B2 ATPase Na+/K+ transporting subunit beta 2 ISO SMPDB SMP:00090 NCBI chr 5:32,548,591...32,553,911
Ensembl chr 5:32,549,167...32,553,504 		JBrowse link
G ATP1B3 ATPase Na+/K+ transporting subunit beta 3 ISO SMPDB SMP:00090 NCBI chr23:37,684,507...37,727,535
Ensembl chr23:37,684,506...37,726,746 		JBrowse link
G ATP1B4 ATPase Na+/K+ transporting family member beta 4 ISO SMPDB SMP:00090 NCBI chr  X:92,347,443...92,368,206
Ensembl chr  X:92,347,684...92,365,341 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 ISO SMPDB SMP:00090 NCBI chr 5:15,812,335...15,824,552
Ensembl chr 5:15,815,969...15,823,057 		JBrowse link
G NR3C2 nuclear receptor subfamily 3 group C member 2 ISO SMPDB SMP:00090 NCBI chr15:46,390,030...46,718,000
Ensembl chr15:46,390,023...46,710,131 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha ISO SMPDB SMP:00090 NCBI chr27:38,612,206...38,638,212
Ensembl chr27:38,612,194...38,638,980 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta ISO SMPDB SMP:00090 NCBI chr 6:22,439,643...22,481,349
Ensembl chr 6:22,439,643...22,481,349 		JBrowse link
G SCNN1D sodium channel epithelial 1 subunit delta ISO SMPDB SMP:00090 NCBI chr 5:56,455,677...56,466,035
Ensembl chr 5:56,461,939...56,465,595 		JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma ISO SMPDB SMP:00090 NCBI chr 6:22,566,568...22,593,479
Ensembl chr 6:22,567,711...22,593,503 		JBrowse link
G SLC12A1 solute carrier family 12 member 1 ISO SMPDB SMP:00090 NCBI chr30:14,458,373...14,548,870
Ensembl chr30:14,459,606...14,547,694 		JBrowse link
G SLC12A3 solute carrier family 12 member 3 ISO SMPDB SMP:00090 NCBI chr 2:59,413,737...59,449,129
Ensembl chr 2:59,413,828...59,449,081 		JBrowse link
G SLC12A6 solute carrier family 12 member 6 ISO SMPDB SMP:00090 NCBI chr30:773,021...860,936
Ensembl chr30:773,933...858,487 		JBrowse link
G SLC14A2 solute carrier family 14 member 2 ISO SMPDB SMP:00090 NCBI chr 7:45,435,387...45,868,977
Ensembl chr 7:45,431,450...45,490,430 		JBrowse link
G SLC1A1 solute carrier family 1 member 1 ISO SMPDB SMP:00090 NCBI chr 1:92,898,274...92,978,260
Ensembl chr 1:92,898,274...92,978,260 		JBrowse link
G SLC22A2 solute carrier family 22 member 2 ISO SMPDB SMP:00090 NCBI chr 1:49,327,621...49,348,435
Ensembl chr 1:49,327,296...49,348,435 		JBrowse link
G SLC22A6 solute carrier family 22 member 6 ISO SMPDB SMP:00090 NCBI chr18:53,736,669...53,745,001
Ensembl chr18:53,736,959...53,744,396 		JBrowse link
G SLC38A4 solute carrier family 38 member 4 ISO SMPDB SMP:00090 NCBI chr27:7,685,955...7,756,222
Ensembl chr27:7,685,660...7,770,363 		JBrowse link
G SLC3A1 solute carrier family 3 member 1 ISO SMPDB SMP:00090 NCBI chr10:46,690,555...46,737,417
Ensembl chr10:46,685,137...46,737,147 		JBrowse link
G SLC3A2 solute carrier family 3 member 2 ISO SMPDB SMP:00090 NCBI chr18:53,810,468...53,819,021
Ensembl chr18:53,810,398...53,819,021 		JBrowse link
G SLC6A20 solute carrier family 6 member 20 ISO SMPDB SMP:00090 NCBI chr20:42,702,368...42,725,804
Ensembl chr20:42,702,379...42,724,658 		JBrowse link
G SLC7A5 solute carrier family 7 member 5 ISO SMPDB SMP:00090 NCBI chr 5:65,313,105...65,343,858
Ensembl chr 5:65,313,105...65,343,858 		JBrowse link
G SLC7A6 solute carrier family 7 member 6 ISO SMPDB SMP:00090 NCBI chr 5:81,229,251...81,267,325
Ensembl chr 5:81,231,680...81,252,295 		JBrowse link
G SLC7A7 solute carrier family 7 member 7 ISO SMPDB SMP:00090 NCBI chr 8:3,132,735...3,209,259
Ensembl chr 8:3,133,139...3,165,832 		JBrowse link
G SLC7A8 solute carrier family 7 member 8 ISO SMPDB SMP:00090 NCBI chr 8:3,430,208...3,479,985
Ensembl chr 8:3,430,208...3,479,985 		JBrowse link
G SLC7A9 solute carrier family 7 member 9 ISO SMPDB SMP:00090 NCBI chr 1:119,205,833...119,229,054
Ensembl chr 1:119,205,833...119,229,054 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 4047
    drug pathway 379
      cardiovascular system drug pathway 177
        diuretic drug pathway 32
          bendroflumethiazide drug pathway 32
            bendroflumethiazide pharmacodynamics pathway 32
paths to the root