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Pathways
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PATHWAY ONTOLOGY - ANNOTATIONS

The Pathway Ontology (PW), is currently being developed at the Rat Genome Database. For more information about this vocabulary, please see Petri et al. The rat genome database pathway portal. Database (Oxford). 2011 Apr 8;2011:bar010. Print 2011 or contact us (http://rgd.mcw.edu/contact/index.shtml).
Term:imipramine pharmacokinetics pathway
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Accession:PW:0001986 term browser browse the term
Definition:The pathway of processing - absorption, distribution, metabolism or elimination - of imipramine. Genetic variations can result in changes in the availability of the drug.
Synonyms:related_synonym: SMP:00625


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imipramine pharmacokinetics pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP1A2 cytochrome P450 family 1 subfamily A member 2 EXP SMPDB SMP:00625 NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607 		JBrowse link
G CYP2C19 cytochrome P450 family 2 subfamily C member 19 EXP SMPDB SMP:00625 NCBI chr10:94,762,681...94,855,547
Ensembl chr10:94,762,681...94,855,547 		JBrowse link
G CYP2D6 cytochrome P450 family 2 subfamily D member 6 EXP SMPDB SMP:00625 NCBI chr22:42,126,499...42,130,810
Ensembl chr22:42,126,499...42,130,865 		JBrowse link
G CYP3A4 cytochrome P450 family 3 subfamily A member 4 EXP SMPDB SMP:00625 NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 EXP SMPDB SMP:00625 NCBI chr16:55,655,988...55,706,192
Ensembl chr16:55,655,988...55,707,645 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 EXP SMPDB SMP:00625 NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  pathway 5956
    drug pathway 412
      nervous system drug pathway 196
        antidepressant drug pathway 41
          non-selective monoamine reuptake inhibitor drug pathway 35
            imipramine drug pathway 34
              imipramine pharmacokinetics pathway 6
paths to the root