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Gene: CYP2D6 (cytochrome P450 family 2 subfamily D member 6) Homo sapiens
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Symbol: CYP2D6
Name: cytochrome P450 family 2 subfamily D member 6
Description: Exhibits anandamide epoxidase activity; drug binding activity; and heme binding activity. Involved in several processes, including cellular hormone metabolic process; coumarin metabolic process; and negative regulation of cellular organofluorine metabolic process. Localizes to mitochondrion. Implicated in acute lymphoblastic leukemia; acute myeloid leukemia; asthma; autoimmune hepatitis; and rhinitis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cholesterol 25-hydroxylase; CPD6; CYP2D; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2D@; CYP2DL1; CYPIID6; cytochrome p450 2d18; cytochrome P450 2D6; cytochrome P450, family 2, subfamily D, polypeptide 6; cytochrome P450, family 2, subfamily D, polypeptide 7 pseudogene 2; cytochrome P450, family 2, subfamily D, polypeptide 8 pseudogene 2; cytochrome P450, subfamily II (debrisoquine, sparteine, etc., -metabolising), polypeptide 7 pseudogene 2; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolising), polypeptide 8 pseudogene 2; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing), polypeptide 6; cytochrome P450, subfamily IID (debrisoquine, sparteine, etc., -metabolizing)-like 1; cytochrome P450-DB1; debrisoquine 4-hydroxylase; flavoprotein-linked monooxygenase; MGC120389; MGC120390; microsomal monooxygenase; nonfunctional cytochrome P450 2D6; P450-DB1; P450C2D; P450DB1; xenobiotic monooxygenase
Orthologs:
Related Pseudogenes: CYP2D7BP   CYP2D8P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2242,126,499 - 42,130,881 (-)EnsemblGRCh38hg38GRCh38
GRCh382242,126,499 - 42,130,810 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372242,522,501 - 42,526,883 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362240,852,445 - 40,856,827 (-)NCBINCBI36hg18NCBI36
Build 342240,847,000 - 40,851,379NCBI
Celera2226,328,694 - 26,333,076 (-)NCBI
Cytogenetic Map22q13.2NCBI
HuRef2225,488,519 - 25,492,901 (-)NCBIHuRef
CHM1_12242,482,242 - 42,486,624 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences