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ONTOLOGY REPORT - ANNOTATIONS

Term:NAD-dependent histone decrotonylase activity
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Accession:GO:0160012 term browser browse the term
Definition:Catalysis of the reaction: H2O + N6-(2E)-butenoyl-L-lysyl-[histone] + NAD+ = 2''-O-(2E)-but-2-enoyl-ADP-D-ribose + L-lysyl-[histone] + nicotinamide.


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NAD-dependent histone decrotonylase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sirt1 sirtuin 1 enables ISS
ISO		 GO_REF:0000024
(PMID:28497810)		 UniProt
RGD		 PMID:28497810 GO_REF:0000024 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6153
      catalytic activity, acting on a protein 2516
        histone modifying activity 233
          histone decrotonylase activity 5
            NAD-dependent histone decrotonylase activity 1
              histone H3K18 decrotonylase activity 0
Path 2
Term Annotations click to browse term
  molecular_function 21010
    catalytic activity 6153
      hydrolase activity 2639
        hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 135
          hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 77
            protein decrotonylase activity 6
              histone decrotonylase activity 5
                NAD-dependent histone decrotonylase activity 1
                  histone H3K18 decrotonylase activity 0
paths to the root