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ONTOLOGY REPORT - ANNOTATIONS

Term:protein K11-linked ubiquitination
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Accession:GO:0070979 term browser browse the term
Definition:A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.

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protein K11-linked ubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Anapc1 anaphase promoting complex subunit 1 involved_in ISO (PMID:18485873), (PMID:29033132) UniProt PMID:18485873 PMID:29033132 NCBI chrNW_004955470:2,182,163...2,262,804
Ensembl chrNW_004955470:2,183,766...2,262,900 		JBrowse link
G Anapc10 anaphase promoting complex subunit 10 involved_in ISO (PMID:18485873), (PMID:29033132) UniProt PMID:18485873 PMID:29033132 NCBI chrNW_004955428:945,238...1,029,818
Ensembl chrNW_004955428:941,659...1,029,799 		JBrowse link
G Anapc13 anaphase promoting complex subunit 13 involved_in ISO (PMID:18485873), (PMID:29033132) UniProt PMID:18485873 PMID:29033132 NCBI chrNW_004955501:4,096,026...4,103,212
Ensembl chrNW_004955501:4,096,026...4,103,212 		JBrowse link
G Anapc15 anaphase promoting complex subunit 15 involved_in ISO (PMID:29033132) UniProt PMID:29033132 NCBI chrNW_004955414:19,218,727...19,222,138
Ensembl chrNW_004955414:19,218,727...19,222,138 		JBrowse link
G Anapc16 anaphase promoting complex subunit 16 involved_in ISO (PMID:29033132) UniProt PMID:29033132 NCBI chrNW_004955437:19,367,662...19,381,607
Ensembl chrNW_004955437:19,367,662...19,381,603 		JBrowse link
G Anapc2 anaphase promoting complex subunit 2 involved_in ISO (PMID:18485873), (PMID:29033132) UniProt PMID:18485873 PMID:29033132 NCBI chrNW_004955513:5,183,472...5,194,253
Ensembl chrNW_004955513:5,183,472...5,194,253 		JBrowse link
G Anapc4 anaphase promoting complex subunit 4 involved_in ISO (PMID:18485873), (PMID:29033132) UniProt PMID:18485873 PMID:29033132 NCBI chrNW_004955443:19,620,480...19,653,179
Ensembl chrNW_004955443:19,620,480...19,653,200 		JBrowse link
G Anapc5 anaphase promoting complex subunit 5 involved_in ISO (PMID:18485873), (PMID:29033132) UniProt PMID:18485873 PMID:29033132 NCBI chrNW_004955482:6,951,496...6,980,498
Ensembl chrNW_004955482:6,951,228...6,980,382 		JBrowse link
G Anapc7 anaphase promoting complex subunit 7 involved_in ISO (PMID:18485873), (PMID:29033132) UniProt PMID:18485873 PMID:29033132 NCBI chrNW_004955482:7,302,853...7,328,145
Ensembl chrNW_004955482:7,302,455...7,328,145 		JBrowse link
G Arel1 apoptosis resistant E3 ubiquitin protein ligase 1 involved_in ISO (PMID:25752577) UniProt PMID:25752577 NCBI chrNW_004955523:818,535...874,189
Ensembl chrNW_004955523:818,535...874,189 		JBrowse link
G Cdc16 cell division cycle 16 involved_in ISO (PMID:18485873), (PMID:29033132) UniProt PMID:18485873 PMID:29033132 NCBI chrNW_004955404:47,126...71,602
Ensembl chrNW_004955404:45,383...71,466 		JBrowse link
G Cdc23 cell division cycle 23 involved_in ISO (PMID:18485873), (PMID:29033132) UniProt PMID:18485873 PMID:29033132 NCBI chrNW_004955418:2,194,937...2,221,928
Ensembl chrNW_004955418:2,194,689...2,221,928 		JBrowse link
G Cdc26 cell division cycle 26 involved_in ISO (PMID:18485873), (PMID:29033132) UniProt PMID:18485873 PMID:29033132 NCBI chrNW_004955419:14,206,167...14,218,487
Ensembl chrNW_004955419:14,205,691...14,218,595 		JBrowse link
G Cdc27 cell division cycle 27 involved_in ISO (PMID:18485873), (PMID:29033132) UniProt PMID:18485873 PMID:29033132 NCBI chrNW_004955478:9,927,871...10,002,020
Ensembl chrNW_004955478:9,927,871...10,002,020 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISO (PMID:25621951) UniProt PMID:25621951 NCBI chrNW_004955439:18,664,230...19,953,358
Ensembl chrNW_004955439:18,664,379...19,951,152 		JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO (PMID:35343654) UniProt PMID:35343654 NCBI chrNW_004955568:263,302...349,192
Ensembl chrNW_004955568:263,302...349,192 		JBrowse link
G Rnf26 ring finger protein 26 involved_in ISO (PMID:25254379) UniProt PMID:25254379 NCBI chrNW_004955412:20,415,468...20,418,263
Ensembl chrNW_004955412:20,416,067...20,417,368 		JBrowse link
G Rnf4 ring finger protein 4 involved_in ISO PMID:18408734 UniProt PMID:18408734 RGD:8553731 NCBI chrNW_004955514:1,501,943...1,525,689
Ensembl chrNW_004955514:1,511,062...1,523,714 		JBrowse link
G Trim26 tripartite motif containing 26 involved_in ISO (PMID:34017102) UniProt PMID:34017102 NCBI chrNW_004955583:303,081...325,560
Ensembl chrNW_004955583:303,081...325,560 		JBrowse link
G Ube2a ubiquitin conjugating enzyme E2 A involved_in ISO (PMID:20061386) UniProt PMID:20061386 NCBI chrNW_004955534:411,602...485,964
Ensembl chrNW_004955534:409,947...421,888 		JBrowse link
G Ube2b ubiquitin conjugating enzyme E2 B involved_in ISO (PMID:20061386) UniProt PMID:20061386 NCBI chrNW_004955408:5,552,619...5,572,145
Ensembl chrNW_004955408:5,552,619...5,572,145 		JBrowse link
G Ube2c ubiquitin conjugating enzyme E2 C involved_in ISO (PMID:18485873), (PMID:19822757), (PMID:20061386) UniProt PMID:18485873 PMID:19822757 PMID:20061386 NCBI chrNW_004955445:11,474,826...11,479,479
Ensembl chrNW_004955445:11,469,063...11,478,759 		JBrowse link
G Ube2d3 ubiquitin conjugating enzyme E2 D3 involved_in ISO (PMID:20061386) UniProt PMID:20061386 NCBI chrNW_004955496:5,694,471...5,727,003
Ensembl chrNW_004955496:5,697,276...5,727,003 		JBrowse link
G Ube2d4 ubiquitin conjugating enzyme E2 D4 (putative) involved_in ISO (PMID:20061386) UniProt PMID:20061386 NCBI chrNW_004955456:7,928,715...7,952,155
Ensembl chrNW_004955456:7,924,977...7,952,155 		JBrowse link
G Ube2e2 ubiquitin conjugating enzyme E2 E2 involved_in ISO (PMID:20061386) UniProt PMID:20061386 NCBI chrNW_004955430:15,122,373...15,442,264
Ensembl chrNW_004955430:15,122,377...15,441,523 		JBrowse link
G Ube2e3 ubiquitin conjugating enzyme E2 E3 involved_in ISO (PMID:20061386) UniProt PMID:20061386 NCBI chrNW_004955403:16,151,629...16,239,855
Ensembl chrNW_004955403:16,151,629...16,239,855 		JBrowse link
G Ube2h ubiquitin conjugating enzyme E2 H involved_in ISO (PMID:20061386) UniProt PMID:20061386 NCBI chrNW_004955479:10,535,851...10,650,252
Ensembl chrNW_004955479:10,535,470...10,650,252 		JBrowse link
G Ube2l3 ubiquitin conjugating enzyme E2 L3 involved_in ISO (PMID:20061386) UniProt PMID:20061386 NCBI chrNW_004955442:17,487,815...17,581,675
Ensembl chrNW_004955442:17,487,815...17,581,675 		JBrowse link
G Ube2s ubiquitin conjugating enzyme E2 S acts_upstream_of_or_within
involved_in		 ISO (PMID:21376237)
(PMID:19822757), (PMID:20061386), (PMID:20622874)		 MGI
UniProt		 PMID:19822757 PMID:20061386 PMID:20622874 PMID:21376237 NCBI chrNW_004955567:854,518...859,606
Ensembl chrNW_004955567:854,518...859,993 		JBrowse link
G Ube2t ubiquitin conjugating enzyme E2 T involved_in ISO (PMID:20061386) UniProt PMID:20061386 NCBI chrNW_004955406:38,391,824...38,400,946
Ensembl chrNW_004955406:38,391,785...38,400,995 		JBrowse link
G Ube2w ubiquitin conjugating enzyme E2 W involved_in ISO (PMID:20061386) UniProt PMID:20061386 NCBI chrNW_004955444:6,454,043...6,536,719
Ensembl chrNW_004955444:6,454,049...6,509,505 		JBrowse link
G Ubr4 ubiquitin protein ligase E3 component n-recognin 4 involved_in ISO (PMID:29033132) UniProt PMID:29033132 NCBI chrNW_004955527:57,335...185,727
Ensembl chrNW_004955527:57,335...185,727 		JBrowse link
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 involved_in ISO (PMID:21118991) UniProt PMID:21118991 NCBI chrNW_004955417:26,997,572...27,085,511
Ensembl chrNW_004955417:26,998,513...27,083,005 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12360
    metabolic process 7487
      primary metabolic process 6455
        protein metabolic process 2873
          protein modification process 1599
            post-translational protein modification 672
              protein modification by small protein conjugation or removal 637
                protein modification by small protein conjugation 561
                  protein ubiquitination 505
                    protein polyubiquitination 225
                      protein K11-linked ubiquitination 33
Path 2
Term Annotations click to browse term
  biological_process 12360
    metabolic process 7487
      organic substance metabolic process 7172
        macromolecule metabolic process 6026
          protein metabolic process 2873
            protein modification process 1599
              post-translational protein modification 672
                protein modification by small protein conjugation or removal 637
                  protein modification by small protein conjugation 561
                    protein ubiquitination 505
                      protein polyubiquitination 225
                        protein K11-linked ubiquitination 33
paths to the root