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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA (guanosine(9)-N1)-methyltransferase activity
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Accession:GO:0052905 term browser browse the term
Definition:Catalysis of the reaction: guanosine9 in tRNA + S-adenosyl-L-methionine = H+ + N1-methylguanosine9 in tRNA + S-adenosyl-L-homocysteine.
Synonyms:exact_synonym: tRNA (guanine(9)-N(1))-methyltransferase activity;   tRNA (guanosine(9)-N(1))-methyltransferase activity
 related_synonym: tRNA (guanine-N(1)-)-methyltransferase activity;   tRNA m(1)G(9) Mtase activity;   tRNA m(1)G(9)-methyltransferase activity;   tRNA(m(1)G(9)/m(1)A(9))-methyltransferase activity;   tRNA(m(1)G(9)/m(1)A(9))Mtase activity
 xref: EC:2.1.1.221;   MetaCyc:RXN-12459;   RHEA:43156;   Reactome:R-HSA-6786621 "TRMT10A methylates guanosine-9 in tRNA";   Reactome:R-HSA-6787591 "TRMT10C:HSD17B10 (TRMT10C:SDR5C1) of mitochondrial RNase P methylates guanosine-9 in tRNA yielding 1-methylguanosine-9"


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tRNA (guanosine(9)-N1)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TRMT10A tRNA methyltransferase 10A enables IEA UniProt
Ensembl		 GO_REF:0000003 GO_REF:0000107 NCBI chr 4:91,970,440...91,987,722
Ensembl chr 4:102,631,501...102,648,454 		JBrowse link
G TRMT10B tRNA methyltransferase 10B enables IEA UniProt
Ensembl		 GO_REF:0000003 GO_REF:0000107 NCBI chr 9:37,602,757...37,628,693
Ensembl chr 9:38,526,496...38,551,902 		JBrowse link
G TRMT10C tRNA methyltransferase 10C, mitochondrial RNase P subunit enables ISO (PMID:23042678) GO_Central PMID:23042678 NCBI chr 3:98,671,176...98,675,743 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 17493
    catalytic activity 5389
      catalytic activity, acting on a nucleic acid 593
        catalytic activity, acting on RNA 366
          RNA methyltransferase activity 62
            tRNA methyltransferase activity 32
              tRNA (guanine) methyltransferase activity 12
                tRNA (guanosine(9)-N1)-methyltransferase activity 3
Path 2
Term Annotations click to browse term
  molecular_function 17493
    catalytic activity 5389
      transferase activity 2182
        transferase activity, transferring one-carbon groups 213
          methyltransferase activity 201
            RNA methyltransferase activity 62
              tRNA methyltransferase activity 32
                tRNA (guanine) methyltransferase activity 12
                  tRNA (guanosine(9)-N1)-methyltransferase activity 3
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