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ONTOLOGY REPORT - ANNOTATIONS

Term:tRNA (guanine) methyltransferase activity
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Accession:GO:0016423 term browser browse the term
Definition:Catalysis of the reaction: S-adenosyl-L-methionine + guanosine in tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine.
Synonyms:exact_synonym: tRNA (guanosine) methyltransferase activity
 alt_id: GO:0016424


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tRNA (guanine) methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ftsj1 FtsJ RNA 2'-O-methyltransferase 1 enables ISO (PMID:32558197) RGD PMID:32558197 NCBI chr  X:14,243,684...14,256,555
Ensembl chr  X:14,244,050...14,252,030 		JBrowse link
G Tarbp1 TAR (HIV-1) RNA binding protein 1 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr19:54,398,268...54,449,293
Ensembl chr19:54,398,253...54,449,261 		JBrowse link
G Thumpd2 THUMP domain containing 2 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 6:13,924,742...13,976,657
Ensembl chr 6:13,924,765...13,976,657 		JBrowse link
G Thumpd3 THUMP domain containing 3 enables IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 4:146,185,422...146,209,802
Ensembl chr 4:146,185,503...146,211,246 		JBrowse link
G Trmt1l tRNA methyltransferase 1-like enables IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:63,510,097...63,543,268
Ensembl chr13:63,510,204...63,543,266 		JBrowse link
tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ftsj1 FtsJ RNA 2'-O-methyltransferase 1 enables ISO (PMID:25404562), (PMID:26310293), (PMID:36720500) RGD PMID:25404562 PMID:26310293 PMID:36720500 NCBI chr  X:14,243,684...14,256,555
Ensembl chr  X:14,244,050...14,252,030 		JBrowse link
tRNA (guanine(10)-N2)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trmt11 tRNA methyltransferase 11 homolog enables IEA
ISS
ISO		 GO_REF:0000002
GO_REF:0000024
(PMID:37283053)		 InterPro
UniProt
RGD		 PMID:37283053 GO_REF:0000002 GO_REF:0000024 NCBI chr 1:27,054,437...27,109,765
Ensembl chr 1:27,054,420...27,201,610 		JBrowse link
tRNA (guanine(26)-N2)-dimethyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trmt1 tRNA methyltransferase 1 enables ISO (PMID:10982862) RGD PMID:10982862 NCBI chr19:23,456,756...23,471,581
Ensembl chr19:23,456,756...23,466,956 		JBrowse link
tRNA (guanine(37)-N1)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trmt5 tRNA methyltransferase 5 enables IEA GO_REF:0000116
GO_REF:0000104
GO_REF:0000003		 RHEA
UniProt		 GO_REF:0000003 GO_REF:0000104 GO_REF:0000116 NCBI chr 6:91,963,558...91,987,660
Ensembl chr 6:91,943,724...91,987,555 		JBrowse link
tRNA (guanine(46)-N7)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mettl1 methyltransferase 1, tRNA methylguanosine enables ISO
IBA		 (PMID:12403464), (PMID:15861136), (PMID:36599982), (PMID:36599985), (PMID:37369656)
GO_REF:0000033		 RGD
GO_Central		 PMID:12403464 PMID:15861136 PMID:36599982 PMID:36599985 PMID:37369656 GO_REF:0000033 NCBI chr 7:62,864,860...62,869,202
Ensembl chr 7:62,864,853...62,869,202 		JBrowse link
tRNA (guanine(6)-N2)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thumpd3 THUMP domain containing 3 enables ISO (PMID:34669960), (PMID:37283053) RGD PMID:34669960 PMID:37283053 NCBI chr 4:146,185,422...146,209,802
Ensembl chr 4:146,185,503...146,211,246 		JBrowse link
tRNA (guanine(7)-N2)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Thumpd3 THUMP domain containing 3 enables ISO (PMID:34669960) RGD PMID:34669960 NCBI chr 4:146,185,422...146,209,802
Ensembl chr 4:146,185,503...146,211,246 		JBrowse link
tRNA (guanosine(9)-N1)-methyltransferase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Trmt10a tRNA methyltransferase 10A enables IEA
ISO		 GO_REF:0000003
(PMID:23042678), (PMID:32392304)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:23042678 PMID:32392304 GO_REF:0000003 GO_REF:0000107 NCBI chr 2:226,669,445...226,684,166
Ensembl chr 2:226,669,832...226,684,151 		JBrowse link
G Trmt10b tRNA methyltransferase 10B enables IEA
ISO		 GO_REF:0000107
(PMID:23042678)		 Ensembl
RGD		 PMID:23042678 GO_REF:0000107 NCBI chr 5:59,548,845...59,572,529
Ensembl chr 5:59,548,869...59,572,526 		JBrowse link
G Trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit enables ISO (PMID:23042678) RGD PMID:23042678 NCBI chr11:44,584,388...44,589,466
Ensembl chr11:44,584,113...44,589,568 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 21086
    catalytic activity 6121
      catalytic activity, acting on a nucleic acid 630
        catalytic activity, acting on RNA 389
          RNA methyltransferase activity 63
            tRNA methyltransferase activity 31
              tRNA (guanine) methyltransferase activity 12
                tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase activity 1
                tRNA (guanine(10)-N2)-dimethyltransferase activity 0
                tRNA (guanine(10)-N2)-methyltransferase activity 1
                tRNA (guanine(18)-2'-O)-methyltransferase activity 0
                tRNA (guanine(26)-N2)-dimethyltransferase activity 1
                tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity 0
                tRNA (guanine(37)-N1)-methyltransferase activity 1
                tRNA (guanine(46)-N7)-methyltransferase activity 1
                tRNA (guanine(6)-N2)-methyltransferase activity 1
                tRNA (guanine(7)-N2)-methyltransferase activity 1
                tRNA (guanosine(9)-N1)-methyltransferase activity 3
Path 2
Term Annotations click to browse term
  molecular_function 21086
    catalytic activity 6121
      transferase activity 2441
        transferase activity, transferring one-carbon groups 214
          methyltransferase activity 203
            RNA methyltransferase activity 63
              tRNA methyltransferase activity 31
                tRNA (guanine) methyltransferase activity 12
                  tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase activity 1
                  tRNA (guanine(10)-N2)-dimethyltransferase activity 0
                  tRNA (guanine(10)-N2)-methyltransferase activity 1
                  tRNA (guanine(18)-2'-O)-methyltransferase activity 0
                  tRNA (guanine(26)-N2)-dimethyltransferase activity 1
                  tRNA (guanine(26)-N2/guanine(27)-N2)-dimethyltransferase activity 0
                  tRNA (guanine(37)-N1)-methyltransferase activity 1
                  tRNA (guanine(46)-N7)-methyltransferase activity 1
                  tRNA (guanine(6)-N2)-methyltransferase activity 1
                  tRNA (guanine(7)-N2)-methyltransferase activity 1
                  tRNA (guanosine(9)-N1)-methyltransferase activity 3
paths to the root