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ONTOLOGY REPORT - ANNOTATIONS

Term:alphav-beta3 integrin-IGF-1-IGF1R complex
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Accession:GO:0035867 term browser browse the term
Definition:A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits.


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alphav-beta3 integrin-IGF-1-IGF1R complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGF1 insulin like growth factor 1 part_of ISO (PMID:19578119) UniProt PMID:19578119 NCBI chr12:99,986,887...100,066,773
Ensembl chr12:103,385,911...103,462,177 		JBrowse link
G IGF1R insulin like growth factor 1 receptor part_of IEA Ensembl GO_REF:0000107 NCBI chr15:77,332,926...77,648,474
Ensembl chr15:96,535,164...96,832,974 		JBrowse link
G ITGAV integrin subunit alpha V part_of IEA Ensembl GO_REF:0000107 NCBI chr2B:73,880,962...73,972,486
Ensembl chr2B:191,680,655...191,773,028 		JBrowse link
G ITGB3 integrin subunit beta 3 part_of IEA Ensembl GO_REF:0000107 NCBI chr17:10,134,450...10,194,596
Ensembl chr17:10,353,111...10,392,382 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 17179
    protein-containing complex 5911
      membrane protein complex 1248
        plasma membrane protein complex 578
          alphav-beta3 integrin-IGF-1-IGF1R complex 4
Path 2
Term Annotations click to browse term
  cellular_component 17179
    cellular anatomical entity 16965
      membrane 8102
        plasma membrane 4667
          plasma membrane protein complex 578
            alphav-beta3 integrin-IGF-1-IGF1R complex 4
paths to the root