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ONTOLOGY REPORT - ANNOTATIONS

Term:insulin receptor activity
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Accession:GO:0005009 term browser browse the term
Definition:Combining with insulin receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity.
Synonyms:exact_synonym: insulin-activated receptor activity
 xref: Reactome:R-HSA-74715 "Autophosphorylation of insulin receptor"
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa


show annotations for term's descendants           Sort by:
insulin receptor activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IGF1R insulin like growth factor 1 receptor enables IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:137,383,623...137,691,038
Ensembl chr 1:137,387,825...137,691,058 		JBrowse link
G INSR insulin receptor enables ISO
IEA
IBA		 RGD
Ensembl
GO_Central
TreeGrafter		 PMID:3275643 PMID:12850498 PMID:12891559 PMID:17023527 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 RGD:1299201 RGD:1580595 RGD:1600765 RGD:2293184 NCBI chr 2:71,797,209...71,939,923
Ensembl chr 2:71,797,204...71,936,104 		JBrowse link
G INSRR insulin receptor related receptor enables IEA
IBA		 TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000118 NCBI chr 4:93,239,678...93,258,075
Ensembl chr 4:93,239,969...93,258,075 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 18691
    molecular transducer activity 2621
      signaling receptor activity 2621
        protein-hormone receptor activity 23
          insulin receptor activity 3
Path 2
Term Annotations click to browse term
  molecular_function 18691
    catalytic activity 5667
      transferase activity 2373
        transferase activity, transferring phosphorus-containing groups 948
          kinase activity 801
            protein kinase activity 581
              protein tyrosine kinase activity 122
                transmembrane receptor protein tyrosine kinase activity 61
                  insulin receptor activity 3
paths to the root