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ONTOLOGY REPORT - ANNOTATIONS
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Term:
5'-3' RNA exonuclease activity
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Accession:
GO:0004534
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Definition:
Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule.
Synonyms:
exact_synonym:
5'-3' exoribonuclease activity
xref:
EC:3.1.13; reactome:R-HSA-429845 "5' to 3' exoribonuclease hydrolyzes decapped mRNA"
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Rat (4)
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Genes (4)
5'-3' RNA exonuclease activity
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
CPSF3
cleavage and polyadenylation specific factor 3
enables
IEA
Ensembl
TreeGrafter
GO_REF:0000107 GO_REF:0000118
NCBI chr2A:9,413,517...9,462,758
Ensembl chr2A:9,576,871...9,626,193
G
DCP2
decapping mRNA 2
enables
IEA
Ensembl
GO_REF:0000107
NCBI chr 5:108,333,091...108,377,119
Ensembl chr 5:114,144,999...114,172,480
G
XRN1
5'-3' exoribonuclease 1
enables
IEA
Ensembl
UniProt
GO_REF:0000107 GO_REF:0000117
NCBI chr 3:139,337,337...139,481,479
Ensembl chr 3:146,930,988...147,073,827
G
XRN2
5'-3' exoribonuclease 2
enables
IEA
UniProt
InterPro
GO_REF:0000002 GO_REF:0000104
NCBI chr20:21,260,871...21,347,430
Ensembl chr20:21,222,138...21,308,561
Term paths to the root
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Path 1
Term
Annotations
molecular_function
17493
catalytic activity
5389
catalytic activity, acting on a nucleic acid
593
catalytic activity, acting on RNA
366
RNA nuclease activity
118
RNA exonuclease activity
44
RNA exonuclease activity, producing 5'-phosphomonoesters
34
5'-3' RNA exonuclease activity
4
Path 2
Term
Annotations
molecular_function
17493
catalytic activity
5389
hydrolase activity
2314
hydrolase activity, acting on ester bonds
742
nuclease activity
199
RNA nuclease activity
118
RNA exonuclease activity
44
RNA exonuclease activity, producing 5'-phosphomonoesters
34
5'-3' RNA exonuclease activity
4