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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
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Accession:GO:0002859 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
Synonyms:exact_synonym: down regulation of natural killer cell mediated cytotoxicity directed against tumor cell target;   downregulation of natural killer cell mediated cytotoxicity directed against tumor cell target
 narrow_synonym: inhibition of natural killer cell mediated cytotoxicity directed against tumor cell target


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negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (MGI:5437532|PMID:22842346) UniProt PMID:22842346 MGI:5437532 NCBI chrNW_004936515:6,001,324...6,015,407 JBrowse link
G LOC101954488 CEA cell adhesion molecule 1 involved_in ISO (PMID:23696226)
(MGI:5512785|PMID:23696226)
UniProt PMID:23696226 MGI:5512785 NCBI chrNW_004936706:37,480...53,306 JBrowse link
G LOC101976242 NKG2-D type II integral membrane protein ISO RGD PMID:12782717 RGD:1299590 NCBI chrNW_004936902:216,495...229,150
Ensembl chrNW_004936902:216,495...229,141
JBrowse link
G Tgfb1 transforming growth factor beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936661:3,742,080...3,758,266
Ensembl chrNW_004936661:3,742,066...3,758,272
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15971
    immune system process 2209
      immune response 1399
        immune response to tumor cell 28
          natural killer cell mediated immune response to tumor cell 11
            natural killer cell mediated cytotoxicity directed against tumor cell target 10
              negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 4
Path 2
Term Annotations click to browse term
  biological_process 15971
    response to stimulus 8556
      response to external stimulus 2249
        response to external biotic stimulus 1408
          response to other organism 1404
            defense response to other organism 974
              defense response to symbiont 856
                innate immune response 699
                  natural killer cell mediated immunity 58
                    regulation of natural killer cell mediated immunity 38
                      negative regulation of natural killer cell mediated immunity 15
                        negative regulation of natural killer cell mediated immune response to tumor cell 4
                          negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target 4
paths to the root