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ONTOLOGY REPORT - ANNOTATIONS

Term:immune response to tumor cell
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Accession:GO:0002418 term browser browse the term
Definition:An immune system process that functions in the response of an organism to a tumor cell.


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immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adam15 ADAM metallopeptidase domain 15 involved_in ISO
IEA 		(PMID:22505472)
GO_REF:0000107 		RGD
Ensembl		 PMID:22505472 GO_REF:0000107 NCBI chr 2:174,754,629...174,765,136
Ensembl chr 2:174,754,633...174,765,113 		JBrowse link
G Mill1 MHC I like leukocyte 1 involved_in ISO (PMID:10359807) RGD PMID:10359807 NCBI chr 1:78,372,798...78,398,932
Ensembl chr 1:78,372,802...78,398,930 		JBrowse link
G Prf1 perforin 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:8164737)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:8164737 GO_REF:0000024 GO_REF:0000107 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nkg7 natural killer cell granule protein 7 involved_in ISO (PMID:32839608) RGD PMID:32839608 NCBI chr 1:93,844,748...93,845,975
Ensembl chr 1:93,844,902...93,845,983 		JBrowse link
negative regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS 		(PMID:23696226)
GO_REF:0000024 		RGD
UniProt		 PMID:23696226 GO_REF:0000024 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992 		JBrowse link
G Havcr2 hepatitis A virus cellular receptor 2 involved_in ISO (PMID:22842346) RGD PMID:22842346 NCBI chr10:30,882,484...30,914,018
Ensembl chr10:30,882,606...30,909,137 		JBrowse link
G Klre1 killer cell lectin like receptor E1 IDA RGD PMID:12782717 RGD:1299590 NCBI chr 4:163,033,581...163,041,641
Ensembl chr 4:163,033,563...163,041,638 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO
IEA 		(PMID:24586048)
GO_REF:0000107 		RGD
Ensembl		 PMID:24586048 GO_REF:0000107 NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
negative regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Muc4 mucin 4, cell surface associated IDA RGD PMID:10232613 RGD:2303754 NCBI chr11:68,008,245...68,053,242 JBrowse link
negative regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor involved_in ISO
ISS 		(PMID:32818467)
GO_REF:0000024 		RGD
UniProt		 PMID:32818467 GO_REF:0000024 NCBI chr 6:57,961,423...57,998,901
Ensembl chr 6:52,234,089...52,271,568 		JBrowse link
G Cd274 CD274 molecule involved_in ISO (PMID:28813410), (PMID:28813417) RGD PMID:28813410 PMID:28813417 NCBI chr 1:227,116,674...227,137,379
Ensembl chr 1:227,116,649...227,134,450 		JBrowse link
G Il4i1 interleukin 4 induced 1 involved_in ISO (PMID:32818467)
(PMID:21469114), (PMID:28405502) 		RGD PMID:21469114 PMID:28405502 PMID:32818467 NCBI chr 1:95,299,457...95,324,564
Ensembl chr 1:95,295,601...95,324,562 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 involved_in ISO (PMID:37208329) RGD PMID:37208329 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Pdcd1 programmed cell death 1 involved_in ISO (PMID:38377992) RGD PMID:38377992 NCBI chr 9:94,418,786...94,431,945
Ensembl chr 9:94,418,791...94,431,937 		JBrowse link
G Ufl1 Ufm1-specific ligase 1 involved_in ISO
IEA
ISS 		(PMID:38377992)
GO_REF:0000107
GO_REF:0000024 		RGD
Ensembl
UniProt		 PMID:38377992 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:43,759,271...43,791,682
Ensembl chr 5:38,962,171...38,995,199 		JBrowse link
G Usp5 ubiquitin specific peptidase 5 involved_in ISO (PMID:37208329) RGD PMID:37208329 NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711 		JBrowse link
positive regulation of immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd40lg CD40 ligand IDA RGD PMID:19016771 RGD:2313413 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Gsdme gasdermin E involved_in ISO
IEA 		(PMID:32188940)
GO_REF:0000107 		RGD
Ensembl		 PMID:32188940 GO_REF:0000107 NCBI chr 4:79,258,799...79,321,129
Ensembl chr 4:79,257,804...79,320,806 		JBrowse link
G Hrg histidine-rich glycoprotein involved_in ISS
IBA
ISO 		GO_REF:0000024
GO_REF:0000033
(PMID:22348394)
(PMID:21215706) 		UniProt
GO_Central
RGD		 PMID:21215706 PMID:22348394 GO_REF:0000024 GO_REF:0000033 NCBI chr11:78,054,488...78,069,402
Ensembl chr11:78,054,498...78,069,389 		JBrowse link
G Hrgl1 histidine-rich glycoprotein like 1 involved_in ISS
IBA 		GO_REF:0000024
GO_REF:0000033 		UniProt
GO_Central		 GO_REF:0000024 GO_REF:0000033 NCBI chr11:78,039,371...78,049,353
Ensembl chr11:78,039,376...78,049,353 		JBrowse link
G Ulbp1 UL16 binding protein 1 acts_upstream_of_or_within ISO (PMID:12645935) RGD PMID:12645935 NCBI chr 1:1,694,255...1,716,160 JBrowse link
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd226 CD226 molecule involved_in ISO
IEA 		(PMID:12913096)
GO_REF:0000107 		RGD
Ensembl		 PMID:12913096 GO_REF:0000107 NCBI chr18:82,449,924...82,545,107
Ensembl chr18:82,450,568...82,543,051 		JBrowse link
G Crtam cytotoxic and regulatory T cell molecule involved_in ISO
IBA
IEA 		(PMID:15811952)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:15811952 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:41,340,117...41,377,381
Ensembl chr 8:41,340,837...41,377,343 		JBrowse link
G Il12a interleukin 12A involved_in ISO
IEA 		(PMID:7903063)
GO_REF:0000107 		RGD
Ensembl		 PMID:7903063 GO_REF:0000107 NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734 		JBrowse link
G Il12b interleukin 12B involved_in ISO
IEA 		(PMID:7903063)
GO_REF:0000107 		RGD
Ensembl		 PMID:7903063 GO_REF:0000107 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Nectin2 nectin cell adhesion molecule 2 involved_in ISO
IBA
IEA 		(PMID:12913096)
GO_REF:0000033
GO_REF:0000107 		RGD
GO_Central
Ensembl		 PMID:12913096 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:88,500,086...88,535,474
Ensembl chr 1:79,372,119...79,407,360 		JBrowse link
G Pvr PVR cell adhesion molecule involved_in ISO (PMID:12913096) RGD PMID:12913096 NCBI chr 1:79,561,294...79,576,700
Ensembl chr 1:79,546,879...79,576,715 		JBrowse link
G Raet1ll1 retinoic acid early transcript 1L like 1 IMP RGD PMID:16323246 RGD:9685180 NCBI chr 1:1,397,219...1,437,802
Ensembl chr 1:1,397,230...1,402,656 		JBrowse link
positive regulation of natural killer cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd160 CD160 molecule involved_in ISO
IEA 		(PMID:25711213)
GO_REF:0000107 		RGD
Ensembl		 PMID:25711213 GO_REF:0000107 NCBI chr 2:184,340,820...184,383,421
Ensembl chr 2:184,340,599...184,375,834 		JBrowse link
positive regulation of T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mr1 major histocompatibility complex, class I-related involved_in ISO
IEA 		(PMID:31959982)
GO_REF:0000107 		RGD
Ensembl		 PMID:31959982 GO_REF:0000107 NCBI chr13:67,298,362...67,317,985
Ensembl chr13:67,299,585...67,317,970 		JBrowse link
G Slc22a13 solute carrier family 22 member 13 involved_in ISO (PMID:19282870) RGD PMID:19282870 NCBI chr 8:118,922,367...118,934,020
Ensembl chr 8:118,922,367...118,953,635 		JBrowse link
positive regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd24 CD24 molecule acts_upstream_of_or_within ISO (PMID:7774619) RGD PMID:7774619 NCBI chr20:47,074,353...47,079,662
Ensembl chr20:47,073,512...47,079,662 		JBrowse link
G Fbxo38 F-box protein 38 involved_in ISO
IEA 		(PMID:30487606)
GO_REF:0000107 		RGD
Ensembl		 PMID:30487606 GO_REF:0000107 NCBI chr18:55,956,950...56,004,013
Ensembl chr18:55,956,959...56,003,961 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 involved_in ISO (PMID:10663613) RGD PMID:10663613 NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Klhl22 kelch-like family member 22 involved_in ISO (PMID:33109719) RGD PMID:33109719 NCBI chr11:83,190,891...83,231,746
Ensembl chr11:83,190,891...83,231,770 		JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 involved_in ISO
IEA 		(PMID:38377992)
GO_REF:0000107 		RGD
Ensembl		 PMID:38377992 GO_REF:0000107 NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978 		JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:30282837) RGD PMID:30282837 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258 		JBrowse link
G Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma involved_in ISO
IEA 		(PMID:38377992)
GO_REF:0000107 		RGD
Ensembl		 PMID:38377992 GO_REF:0000107 NCBI chr12:20,744,500...20,772,828
Ensembl chr12:20,744,535...20,772,827 		JBrowse link
regulation of T cell mediated immune response to tumor cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmgb1 high mobility group box 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:23108142) 		UniProt
RGD		 PMID:23108142 GO_REF:0000024 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
T cell mediated cytotoxicity directed against tumor cell target term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G RT1-CE16 RT1 class I, locus CE16 involved_in ISO (PMID:1402688), (PMID:17189421), (PMID:20364150) RGD PMID:1402688 PMID:17189421 PMID:20364150 NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20543
    immune system process 3133
      immune response 2239
        immune response to tumor cell 41
          T cell mediated immune response to tumor cell + 19
          natural killer cell mediated immune response to tumor cell + 14
          negative regulation of immune response to tumor cell + 12
          positive regulation of immune response to tumor cell + 23
          regulation of immune response to tumor cell + 36
          tolerance induction to tumor cell + 0
Path 2
Term Annotations click to browse term
  biological_process 20543
    response to stimulus 11082
      response to biotic stimulus 1946
        response to tumor cell 58
          immune response to tumor cell 41
            T cell mediated immune response to tumor cell + 19
            natural killer cell mediated immune response to tumor cell + 14
            negative regulation of immune response to tumor cell + 12
            positive regulation of immune response to tumor cell + 23
            regulation of immune response to tumor cell + 36
            tolerance induction to tumor cell + 0
paths to the root