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ONTOLOGY REPORT - ANNOTATIONS

Term:midbrain dopaminergic neuron differentiation
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Accession:GO:1904948 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron.
Synonyms:exact_synonym: DA neurogenesis from midbrain floor plate;   mDA neuron differentiation;   midbrain DA neurogenesis;   midbrain dopaminergic neuron production

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midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CSNK1D casein kinase 1 delta involved_in ISO (PMID:17244647) ParkinsonsUK-UCL PMID:17244647 NCBI chr16:74,157,875...74,192,142
Ensembl chr16:74,160,648...74,192,108 		JBrowse link
G CTNNB1 catenin beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:2,679,488...2,725,034
Ensembl chr22:2,684,022...2,723,949 		JBrowse link
G LMX1A LIM homeobox transcription factor 1 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr25:63,533,442...63,688,124
Ensembl chr25:63,640,244...63,686,106 		JBrowse link
G RAC1 Rac family small GTPase 1 involved_in ISO (PMID:18953410), (PMID:23109420) ParkinsonsUK-UCL PMID:18953410 PMID:23109420 NCBI chr28:15,583,609...15,610,753
Ensembl chr28:15,583,516...15,610,328 		JBrowse link
G RYK receptor like tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:56,127,048...56,217,407
Ensembl chr15:56,127,130...56,216,407 		JBrowse link
G WNT1 Wnt family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:45,217,402...45,222,996
Ensembl chr11:45,219,027...45,222,017 		JBrowse link
G WNT2 Wnt family member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr21:85,955,517...86,005,664
Ensembl chr21:85,955,145...86,001,730 		JBrowse link
G WNT3 Wnt family member 3 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr16:60,473,029...60,484,673 JBrowse link
G WNT5A Wnt family member 5A involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:16,809,454...16,836,815
Ensembl chr22:16,809,451...16,825,048 		JBrowse link
G WNT9B Wnt family member 9B involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:60,560,132...60,596,782
Ensembl chr16:60,581,258...60,586,596 		JBrowse link
positive regulation of midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DKK1 dickkopf WNT signaling pathway inhibitor 1 involved_in ISO (PMID:21347250) ParkinsonsUK-UCL PMID:21347250 NCBI chr 9:78,836,803...78,840,158
Ensembl chr 9:78,835,162...78,840,146 		JBrowse link
regulation of midbrain dopaminergic neuron differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:39,243,775...39,289,050
Ensembl chr 8:39,243,780...39,288,984 		JBrowse link
G SFRP2 secreted frizzled related protein 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:100,336,442...100,345,093
Ensembl chr 7:100,336,119...100,345,086 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19829
    developmental process 6858
      anatomical structure development 6432
        midbrain development 100
          midbrain dopaminergic neuron differentiation 13
            negative regulation of midbrain dopaminergic neuron differentiation 0
            positive regulation of midbrain dopaminergic neuron differentiation 1
            regulation of midbrain dopaminergic neuron differentiation + 3
Path 2
Term Annotations click to browse term
  biological_process 19829
    developmental process 6858
      anatomical structure development 6432
        multicellular organism development 5173
          system development 4482
            nervous system development 2806
              neurogenesis 2070
                generation of neurons 1793
                  neuron differentiation 1709
                    dopaminergic neuron differentiation 50
                      midbrain dopaminergic neuron differentiation 13
                        negative regulation of midbrain dopaminergic neuron differentiation 0
                        positive regulation of midbrain dopaminergic neuron differentiation 1
                        regulation of midbrain dopaminergic neuron differentiation + 3
paths to the root