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ONTOLOGY REPORT - ANNOTATIONS

Term:presynaptic active zone assembly
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Accession:GO:1904071 term browser browse the term
Definition:The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
Synonyms:exact_synonym: pre-synaptic active zone assembly;   pre-synaptic active zone formation;   presynaptic active zone formation
 narrow_synonym: pre-synaptic active zone component assembly;   pre-synaptic active zone component formation


show annotations for term's descendants           Sort by:
presynaptic active zone assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BSN bassoon presynaptic cytomatrix protein involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:49,554,477...49,673,130
Ensembl chr 3:49,554,477...49,671,549 		JBrowse link
G PCDH17 protocadherin 17 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23684785) Ensembl
MGI		 PMID:23684785 GO_REF:0000107 NCBI chr13:57,630,108...57,729,311
Ensembl chr13:57,631,744...57,729,311 		JBrowse link
G PCLO piccolo presynaptic cytomatrix protein involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:82,754,012...83,162,884
Ensembl chr 7:82,754,012...83,162,930 		JBrowse link
positive regulation of presynaptic active zone assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NLGN1 neuroligin 1 involved_in ISO PMID:15797875 BHF-UCL PMID:15797875 RGD:8554205 NCBI chr 3:173,395,952...174,294,372
Ensembl chr 3:173,396,284...174,294,372 		JBrowse link
G NRXN1 neurexin 1 involved_in TAS (PMID:15797875) BHF-UCL PMID:15797875 NCBI chr 2:49,918,503...51,032,132
Ensembl chr 2:49,918,503...51,225,575 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20482
    cellular process 19724
      cellular component organization or biogenesis 7902
        cellular component organization 7672
          cellular component assembly 3750
            presynaptic active zone assembly 5
              negative regulation of presynaptic active zone assembly 0
              positive regulation of presynaptic active zone assembly 2
              regulation of presynaptic active zone assembly + 2
Path 2
Term Annotations click to browse term
  biological_process 20482
    cellular process 19724
      cellular component organization or biogenesis 7902
        cellular component organization 7672
          cellular component assembly 3750
            cell junction assembly 606
              synapse assembly 340
                presynapse assembly 55
                  presynaptic active zone assembly 5
                    negative regulation of presynaptic active zone assembly 0
                    positive regulation of presynaptic active zone assembly 2
                    regulation of presynaptic active zone assembly + 2
paths to the root