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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of microglial cell activation
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Accession:GO:1903978 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of microglial cell activation.


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regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATM ATM serine/threonine kinase ISO RGD PMID:28007901 RGD:12879399 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207 		JBrowse link
G HSPA4 heat shock protein family A (Hsp70) member 4 ISO rat gene in mouse model RGD PMID:17473852 RGD:5688754 NCBI chr11:21,290,603...21,363,701
Ensembl chr11:21,290,621...21,505,122 		JBrowse link
G SPHK1 sphingosine kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,311,698...4,314,773
Ensembl chr 9:4,311,683...4,314,483 		JBrowse link
negative regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CST7 cystatin F involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:28251676) Ensembl
MGI		 PMID:28251676 GO_REF:0000107 NCBI chr23:1,136,161...1,145,411
Ensembl chr23:1,136,258...1,144,983 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 involved_in ISO PMID:19627440 ARUK-UCL PMID:19627440 RGD:13673772 NCBI chr 2:59,022,794...59,032,095
Ensembl chr 2:59,022,794...59,032,095 		JBrowse link
G GRN granulin precursor involved_in ISO (MGI:5440302|PMID:23041626) UniProt PMID:23041626 MGI:5440302 NCBI chr 9:19,077,430...19,085,443
Ensembl chr 9:19,077,427...19,082,268 		JBrowse link
G LDLR low density lipoprotein receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr20:50,115,175...50,152,443
Ensembl chr20:50,048,736...50,152,355 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:22,461,556...22,469,243
Ensembl chr 9:22,461,705...22,469,053 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma involved_in ISO (MGI:6270781|PMID:30412727) ARUK-UCL PMID:30412727 MGI:6270781 NCBI chr20:6,134,618...6,265,481
Ensembl chr20:6,050,357...6,207,981 		JBrowse link
G SYT11 synaptotagmin 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:41,910,102...41,929,020
Ensembl chr 7:41,912,920...41,929,617 		JBrowse link
G TAFA3 TAFA chemokine like family member 3 acts_upstream_of_or_within ISO (PMID:25595455) MGI PMID:25595455
G TAFA3 TAFA chemokine like family member 3 involved_in IEA Ensembl GO_REF:0000107
positive regulation of microglial cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CTSC cathepsin C acts_upstream_of_or_within ISO (PMID:28251676) MGI PMID:28251676 NCBI chr21:11,659,296...11,692,957
Ensembl chr21:11,659,292...11,692,816 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ISO RGD PMID:21750563 RGD:329955444 NCBI chr 1:111,391,464...111,407,612
Ensembl chr 1:111,391,159...111,407,701 		JBrowse link
G LRRK2 leucine rich repeat kinase 2 ISO RGD PMID:22302802 RGD:13462052 NCBI chr27:13,282,824...13,420,917
Ensembl chr27:13,283,756...13,420,870 		JBrowse link
G MMP8 matrix metallopeptidase 8 involved_in
acts_upstream_of		 IEA
ISO		 (MGI:6201889|PMID:25049354) Ensembl
ARUK-UCL		 PMID:25049354 GO_REF:0000107 MGI:6201889 NCBI chr 5:29,036,381...29,047,180
Ensembl chr 5:29,035,820...29,046,808 		JBrowse link
G STAP1 signal transducing adaptor family member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:58,091,457...58,148,902
Ensembl chr13:58,091,477...58,133,711 		JBrowse link
G TAFA3 TAFA chemokine like family member 3 acts_upstream_of_or_within ISO (PMID:25595455) MGI PMID:25595455
G TAFA3 TAFA chemokine like family member 3 involved_in IEA Ensembl GO_REF:0000107
G TREML1 triggering receptor expressed on myeloid cells like 1 involved_in ISO (PMID:24990881) UniProt PMID:24990881 NCBI chr12:9,915,692...9,928,322
Ensembl chr12:9,915,677...9,928,174 		JBrowse link
G TTBK1 tau tubulin kinase 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:11,738,466...11,774,663
Ensembl chr12:11,738,232...11,757,814 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17307
    cellular process 16207
      cell activation 1162
        glial cell activation 62
          microglial cell activation 50
            regulation of microglial cell activation 19
              negative regulation of microglial cell activation 9
              positive regulation of microglial cell activation 9
Path 2
Term Annotations click to browse term
  biological_process 17307
    biological regulation 12007
      regulation of biological process 11676
        regulation of response to stimulus 3983
          regulation of response to stress 1400
            regulation of defense response 840
              regulation of inflammatory response 411
                regulation of neuroinflammatory response 30
                  regulation of microglial cell activation 19
                    negative regulation of microglial cell activation 9
                    positive regulation of microglial cell activation 9
paths to the root