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ONTOLOGY REPORT - ANNOTATIONS

Term:transport across blood-brain barrier
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Accession:GO:0150104 term browser browse the term
Definition:The directed movement of substances (e.g. macromolecules, small molecules, ions) through the blood-brain barrier.
Synonyms:exact_synonym: transport across BBB
 only_in_taxon: NCBITaxon:6072 ! Eumetazoa


show annotations for term's descendants           Sort by:
transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGER advanced glycosylation end-product specific receptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:31,828,363...31,831,981
Ensembl chr 6:32,708,251...32,711,641 		JBrowse link
G FLVCR2 FLVCR choline and putative heme transporter 2 acts_upstream_of_or_within
involved_in		 ISO (PMID:38693257)
(PMID:38302740), (PMID:38693257)		 MGI
UniProt		 PMID:38302740 PMID:38693257 NCBI chr14:56,132,370...56,209,882 JBrowse link
G LRP1 LDL receptor related protein 1 involved_in ISO (PMID:20630619), (PMID:26619118) ARUK-UCL PMID:20630619 PMID:26619118 NCBI chr12:31,713,938...31,799,287
Ensembl chr12:31,966,149...32,051,979 		JBrowse link
G SLC16A2 solute carrier family 16 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:63,673,992...63,787,011
Ensembl chr  X:73,791,200...73,903,727 		JBrowse link
G SLC1A5 solute carrier family 1 member 5 involved_in ISO (PMID:14622120) ARUK-UCL PMID:14622120 NCBI chr19:43,765,001...43,778,981
Ensembl chr19:52,294,655...52,307,529 		JBrowse link
G SLC22A5 solute carrier family 22 member 5 involved_in ISO (PMID:14595704) ARUK-UCL PMID:14595704 NCBI chr 5:127,791,984...127,817,870
Ensembl chr 5:133,954,678...133,979,066 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:1714544) ARUK-UCL
Ensembl		 PMID:1714544 GO_REF:0000107 NCBI chr 1:42,224,273...42,257,184
Ensembl chr 1:43,600,733...43,634,143 		JBrowse link
G SLC2A3 solute carrier family 2 member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:8,045,058...8,062,116
Ensembl chr12:8,408,457...8,423,466 		JBrowse link
G SLC5A1 solute carrier family 5 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr22:13,070,853...13,140,948
Ensembl chr22:30,924,169...30,992,046 		JBrowse link
G SLC5A6 solute carrier family 5 member 6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr2A:27,199,422...27,213,650
Ensembl chr2A:27,288,726...27,301,896 		JBrowse link
lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD36 CD36 molecule (CD36 blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:72,566,478...72,643,517
Ensembl chr 7:86,265,114...86,305,865 		JBrowse link
G FABP5 fatty acid binding protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:77,803,369...77,807,630
Ensembl chr 8:79,426,684...79,430,879 		JBrowse link
G MFSD2A MFSD2 lysolipid transporter A, lysophospholipid involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:39,244,438...39,259,156
Ensembl chr 1:40,569,706...40,584,438 		JBrowse link
G SLC27A1 solute carrier family 27 member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:16,956,000...16,993,429
Ensembl chr19:17,929,785...17,966,171 		JBrowse link
G SLC27A4 solute carrier family 27 member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:99,463,338...99,483,802
Ensembl chr 9:128,133,365...128,151,077 		JBrowse link
negative regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in ISO (PMID:24345162) Alzheimers_University_of_Toronto PMID:24345162 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
positive regulation of lipid transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOE apolipoprotein E involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:41,853,669...41,857,252
Ensembl chr19:50,459,906...50,463,490 		JBrowse link
xenobiotic transport across blood-brain barrier term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB1 ATP binding cassette subfamily B member 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:25053619 GO_REF:0000107 RGD:11252095 NCBI chr 7:79,497,536...79,706,277
Ensembl chr 7:93,147,950...93,243,238 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) involved_in ISO (PMID:25986174) ARUK-UCL PMID:25986174
G ABCC2 ATP binding cassette subfamily C member 2 involved_in ISO PMID:12663688
PMID:17437408		 ARUK-UCL PMID:12663688 PMID:17437408 RGD:14929203 RGD:704399 NCBI chr10:96,385,534...96,458,571
Ensembl chr10:99,889,160...99,947,270 		JBrowse link
G ABCG2 ATP binding cassette subfamily G member 2 (JR blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:80,379,108...80,446,641
Ensembl chr 4:91,101,321...91,170,157 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16641
    localization 5244
      establishment of localization 4573
        transport 4274
          vascular transport 21
            transport across blood-brain barrier 20
              copper ion transport across blood-brain barrier 0
              lipid transport across blood-brain barrier + 6
              negative regulation of transport across blood-brain barrier + 1
              positive regulation of transport across blood-brain barrier + 1
              regulation of transport across blood-brain barrier + 1
              xenobiotic transport across blood-brain barrier 4
Path 2
Term Annotations click to browse term
  biological_process 16641
    multicellular organismal process 7305
      system process 2224
        circulatory system process 581
          vascular process in circulatory system 253
            vascular transport 21
              transport across blood-brain barrier 20
                copper ion transport across blood-brain barrier 0
                lipid transport across blood-brain barrier + 6
                negative regulation of transport across blood-brain barrier + 1
                positive regulation of transport across blood-brain barrier + 1
                regulation of transport across blood-brain barrier + 1
                xenobiotic transport across blood-brain barrier 4
paths to the root