long-chain fatty acid omega-hydroxylase activity - Ontology Report - Rat Genome Database

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Term:	long-chain fatty acid omega-hydroxylase activity	go back to main search page
Accession:	GO:0102033	browse the term
Definition:	Catalysis of the reaction: an omega-methyl-long-chain fatty acid + O2 + reduced [NADPH--hemoprotein reductase] = an omega-hydroxy-long-chain fatty acid + H+ + H2O + oxidized [NADPH--hemoprotein reductase]. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons.
Comment:	While there is not universal consensus on the lengths of short-, medium-, long- and very-long-chain fatty acids, the GO uses the definitions in ChEBI (see CHEBI:26666, CHEBI:59554, CHEBI:15904 and CHEBI:27283).
Synonyms:	related_synonym:	cytochrome P450 fatty acid omega-hydroxylase activity
	xref:	EC:1.14.14.80; MetaCyc:RXN-16394; RHEA:56748

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Genes (8)

long-chain fatty acid omega-hydroxylase activity

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Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 1, subfamily a, polypeptide 1

enables

(PMID:18577768)

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 2, subfamily u, polypeptide 1

enables

GO_REF:0000116
GO_REF:0000003

GO_REF:0000003 GO_REF:0000116

NCBI chr 2:219,849,403...219,866,959
Ensembl chr 2:219,849,407...219,866,882

G

cytochrome P450, family 4, subfamily a, polypeptide 1

enables

GO_REF:0000003
GO_REF:0000116

GO_REF:0000003 GO_REF:0000116

NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464

G

cytochrome P450, family 4, subfamily a, polypeptide 2

enables

GO_REF:0000116
GO_REF:0000003

GO_REF:0000003 GO_REF:0000116

NCBI chr 5:128,922,355...128,934,188
Ensembl chr 5:128,923,615...128,934,165

G

cytochrome P450, family 4, subfamily a, polypeptide 2 like 1

enables

GO_REF:0000003
GO_REF:0000116

GO_REF:0000003 GO_REF:0000116

NCBI chr 5:129,010,501...129,021,087
Ensembl chr 5:128,923,615...129,026,477

G

cytochrome P450, family 4, subfamily a, polypeptide 3

enables

GO_REF:0000116
GO_REF:0000003

GO_REF:0000003 GO_REF:0000116

NCBI chr 5:129,097,571...129,115,488
Ensembl chr 5:129,097,926...129,115,463

G

cytochrome P450, family 4, subfamily f, polypeptide 18

enables

(PMID:11461919), (PMID:15145985), (PMID:18577768)
(PMID:15364545)

PMID:11461919 PMID:15145985 PMID:15364545 PMID:18577768

NCBI chr16:17,763,543...17,804,944
Ensembl chr16:17,707,317...17,804,940

G

cytochrome P450, family 4, subfamily v, polypeptide 3

enables

GO_REF:0000003

GO_REF:0000003

NCBI chr16:46,917,929...46,958,735
Ensembl chr16:46,918,401...46,943,395

Term paths to the root

Path 1
Term	Annotations
molecular_function	20483
catalytic activity	6036
oxidoreductase activity	850
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	238
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	69
fatty acid omega-hydroxylase activity	9
long-chain fatty acid omega-hydroxylase activity	8

paths to the root