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ONTOLOGY REPORT - ANNOTATIONS

Term:fast, calcium ion-dependent exocytosis of neurotransmitter
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Accession:GO:0098746 term browser browse the term
Definition:The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.
Synonyms:exact_synonym: synchronous, calcium ion-dependent exocytosis of neurotransmitter


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fast, calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt1 synaptotagmin 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3040539|PMID:12526776), (MGI:3653150|PMID:9194562), (MGI:69538|PMID:7954835)		 ParkinsonsUK-UCL
RGD		 PMID:7954835 PMID:9194562 PMID:12526776 GO_REF:0000024 MGI:3040539 MGI:3653150 MGI:69538 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    localization 5613
      establishment of localization 4924
        establishment of localization in cell 2136
          synaptic vesicle exocytosis 132
            calcium ion-regulated exocytosis of neurotransmitter 26
              fast, calcium ion-dependent exocytosis of neurotransmitter 1
Path 2
Term Annotations click to browse term
  biological_process 19692
    biological regulation 13305
      regulation of biological process 12902
        signaling 7581
          cell-cell signaling 1459
            synaptic signaling 987
              trans-synaptic signaling 952
                anterograde trans-synaptic signaling 944
                  chemical synaptic transmission 944
                    neurotransmitter secretion 197
                      synaptic vesicle exocytosis 132
                        calcium ion-regulated exocytosis of neurotransmitter 26
                          fast, calcium ion-dependent exocytosis of neurotransmitter 1
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