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ONTOLOGY REPORT - ANNOTATIONS

Term:calcium ion-regulated exocytosis of neurotransmitter
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Accession:GO:0048791 term browser browse the term
Definition:The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels.


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calcium ion-regulated exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1a calcium voltage-gated channel subunit alpha1 A acts_upstream_of_or_within ISO MGI:1856209 (PMID:10670432) RGD PMID:10670432 NCBI chr19:40,425,560...40,724,810
Ensembl chr19:40,425,560...40,724,599 		JBrowse link
G Doc2b double C2 domain beta involved_in IDA
ISO
IEA 		PMID:20150444
(PMID:20150444)
GO_REF:0000107 		RGD
Ensembl		 PMID:20150444 PMID:20150444 GO_REF:0000107, RGD:8554647 NCBI chr10:61,126,295...61,151,533
Ensembl chr10:61,126,295...61,151,533 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 acts_upstream_of_or_within ISO MGI:2152972 (PMID:17124501) RGD PMID:17124501 NCBI chr 9:32,193,352...32,692,998
Ensembl chr 9:32,193,352...32,692,772 		JBrowse link
G Rims2 regulating synaptic membrane exocytosis 2 involved_in
acts_upstream_of_or_within 		ISS
ISO 		GO_REF:0000024
MGI:2152971 (PMID:17124501) 		ParkinsonsUK-UCL
RGD		 PMID:17124501 GO_REF:0000024 NCBI chr 7:72,133,004...72,644,059
Ensembl chr 7:72,133,170...72,645,499 		JBrowse link
G Snap25 synaptosome associated protein 25 involved_in IDA
IEA 		GO_REF:0000117 UniProt
RGD		 PMID:14980208 GO_REF:0000117, RGD:1581082 NCBI chr 3:144,494,579...144,576,449
Ensembl chr 3:144,494,595...144,576,448 		JBrowse link
G Stx1b syntaxin 1B involved_in IEA
ISO 		GO_REF:0000107
(PMID:18703708) 		Ensembl
RGD		 PMID:18703708 GO_REF:0000107 NCBI chr 1:191,846,016...191,864,878
Ensembl chr 1:191,833,743...191,871,633 		JBrowse link
G Syt1 synaptotagmin 1 acts_upstream_of_or_within ISO
IEA 		MGI:1857252 (PMID:21521611)
GO_REF:0000107 		RGD
Ensembl		 PMID:21521611 GO_REF:0000107 NCBI chr 7:45,699,649...46,244,460
Ensembl chr 7:45,702,228...46,244,213 		JBrowse link
G Syt7 synaptotagmin 7 involved_in ISS
ISO 		GO_REF:0000024
(PMID:26738595) 		UniProt
RGD		 PMID:26738595 GO_REF:0000024 NCBI chr 1:216,456,148...216,518,718
Ensembl chr 1:216,456,259...216,518,718 		JBrowse link
fast, calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt1 synaptotagmin 1 involved_in ISS
IEA
ISO 		GO_REF:0000024
GO_REF:0000107
(PMID:12526776), (PMID:7954835), (PMID:9194562) 		ParkinsonsUK-UCL
Ensembl
RGD		 PMID:7954835 PMID:9194562 PMID:12526776 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:45,699,649...46,244,460
Ensembl chr 7:45,702,228...46,244,213 		JBrowse link
negative regulation of calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk5 cyclin-dependent kinase 5 acts_upstream_of_or_within IMP PMID:23699505 ARUK-UCL PMID:23699505 RGD:13792535 NCBI chr 4:11,647,098...11,651,606
Ensembl chr 4:11,647,141...11,652,777 		JBrowse link
positive regulation of calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1b calcium voltage-gated channel subunit alpha1 B involved_in IMP PMID:23699505 ARUK-UCL PMID:23699505 RGD:13792535 NCBI chr 3:27,779,133...27,944,292
Ensembl chr 3:27,779,166...27,944,285 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha acts_upstream_of_or_within IMP PMID:23699505 ARUK-UCL PMID:23699505 RGD:13792535 NCBI chr 2:227,839,058...228,113,560
Ensembl chr 2:227,839,062...228,113,554 		JBrowse link
G Syt1 synaptotagmin 1 involved_in ISS
ISO
IEA 		GO_REF:0000024
(PMID:11242035)
GO_REF:0000107 		UniProt
RGD
Ensembl		 PMID:11242035 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:45,699,649...46,244,460
Ensembl chr 7:45,702,228...46,244,213 		JBrowse link
presynaptic dense core vesicle exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cadps calcium dependent secretion activator involved_in IEA
ISO 		GO_REF:0000107
(PMID:25719439) 		Ensembl
RGD		 PMID:25719439 GO_REF:0000107 NCBI chr15:12,289,803...12,742,786
Ensembl chr15:14,720,726...15,173,211 		JBrowse link
G Rims1 regulating synaptic membrane exocytosis 1 involved_in ISO (PMID:31679900) RGD PMID:31679900 NCBI chr 9:32,193,352...32,692,998
Ensembl chr 9:32,193,352...32,692,772 		JBrowse link
G Snap25 synaptosome associated protein 25 involved_in ISO (PMID:28404788) RGD PMID:28404788 NCBI chr 3:144,494,579...144,576,449
Ensembl chr 3:144,494,595...144,576,448 		JBrowse link
G Stxbp1 syntaxin binding protein 1 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:36,474,428...36,536,120
Ensembl chr 3:36,474,428...36,536,058 		JBrowse link
G Stxbp2 syntaxin binding protein 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr12:1,689,364...1,701,145
Ensembl chr12:6,487,297...6,504,212 		JBrowse link
G Stxbp3 syntaxin binding protein 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 2:199,130,725...199,173,823
Ensembl chr 2:199,130,725...199,173,823 		JBrowse link
G Syt10 synaptotagmin 10 involved_in ISO (PMID:28683263) RGD PMID:28683263 NCBI chr 7:122,737,301...122,800,462
Ensembl chr 7:122,648,419...122,800,462 		JBrowse link
regulation of calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 acts_upstream_of_or_within ISO
IEA 		(PMID:21106823)
GO_REF:0000107 		RGD
Ensembl		 PMID:21106823 GO_REF:0000107 NCBI chr12:39,733,519...39,782,942
Ensembl chr12:39,733,458...39,782,934 		JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 involved_in ISS
ISO 		GO_REF:0000024
(PMID:16782817) 		ParkinsonsUK-UCL
RGD		 PMID:16782817 GO_REF:0000024 NCBI chr13:41,908,179...41,981,611
Ensembl chr13:41,908,051...41,981,611 		JBrowse link
regulation of presynaptic dense core granule exocytosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G P2rx7 purinergic receptor P2X 7 involved_in EXP
IDA 		PMID:24037803 SynGO PMID:24037803 PMID:24037803 RGD:13702177, RGD:13702177 NCBI chr12:39,550,531...39,594,984
Ensembl chr12:39,540,567...39,595,193 		JBrowse link
G Rab11b RAB11B, member RAS oncogene family involved_in IDA
IMP 		PMID:14627637 SynGO PMID:14627637 PMID:14627637 RGD:8554199, RGD:8554199 NCBI chr 7:14,521,448...14,534,589
Ensembl chr 7:15,223,534...15,236,756 		JBrowse link
G Rab3a RAB3A, member RAS oncogene family involved_in IEA
ISO 		GO_REF:0000107
(PMID:31679900) 		Ensembl
RGD		 PMID:31679900 GO_REF:0000107 NCBI chr16:18,718,164...18,722,273
Ensembl chr16:18,718,167...18,721,842 		JBrowse link
G Unc13b unc-13 homolog B involved_in IMP
IEP
IDA 		PMID:31679900 SynGO PMID:31679900 PMID:31679900 PMID:31679900 RGD:155230690, RGD:155230690, RGD:155230690 NCBI chr 5:62,084,809...62,299,884
Ensembl chr 5:62,084,819...62,299,884 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20668
    localization 5832
      establishment of localization 5111
        establishment of localization in cell 2184
          synaptic vesicle exocytosis 139
            calcium ion-regulated exocytosis of neurotransmitter 22
              fast, calcium ion-dependent exocytosis of neurotransmitter 1
              negative regulation of calcium ion-dependent exocytosis of neurotransmitter 1
              positive regulation of calcium ion-dependent exocytosis of neurotransmitter 3
              presynaptic dense core vesicle exocytosis + 11
              regulation of calcium ion-dependent exocytosis of neurotransmitter + 10
              slow, calcium ion-dependent exocytosis of neurotransmitter 0
Path 2
Term Annotations click to browse term
  biological_process 20668
    biological regulation 13899
      regulation of biological process 13475
        signaling 7942
          cell-cell signaling 1503
            synaptic signaling 1021
              trans-synaptic signaling 977
                anterograde trans-synaptic signaling 969
                  chemical synaptic transmission 969
                    neurotransmitter secretion 205
                      synaptic vesicle exocytosis 139
                        calcium ion-regulated exocytosis of neurotransmitter 22
                          fast, calcium ion-dependent exocytosis of neurotransmitter 1
                          negative regulation of calcium ion-dependent exocytosis of neurotransmitter 1
                          positive regulation of calcium ion-dependent exocytosis of neurotransmitter 3
                          presynaptic dense core vesicle exocytosis + 11
                          regulation of calcium ion-dependent exocytosis of neurotransmitter + 10
                          slow, calcium ion-dependent exocytosis of neurotransmitter 0
paths to the root