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ONTOLOGY REPORT - ANNOTATIONS


Term:fast, calcium ion-dependent exocytosis of neurotransmitter
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Accession:GO:0098746 term browser browse the term
Definition:The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.
Synonyms:exact_synonym: synchronous, calcium ion-dependent exocytosis of neurotransmitter



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fast, calcium ion-dependent exocytosis of neurotransmitter term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Syt1 synaptotagmin 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3040539|PMID:12526776), (MGI:3653150|PMID:9194562), (MGI:69538|PMID:7954835)
ParkinsonsUK-UCL
RGD
PMID:7954835 PMID:9194562 PMID:12526776 GO_REF:0000024 MGI:3040539 MGI:3653150 MGI:69538 NCBI chr 7:43,813,204...44,358,020
Ensembl chr 7:43,815,785...44,357,803
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    cellular process 18637
      cellular localization 3075
        establishment of localization in cell 2295
          synaptic vesicle exocytosis 154
            calcium ion-regulated exocytosis of neurotransmitter 22
              fast, calcium ion-dependent exocytosis of neurotransmitter 1
Path 2
Term Annotations click to browse term
  biological_process 19834
    localization 6554
      establishment of localization 4941
        transport 4779
          export from cell 1033
            secretion by cell 978
              signal release 633
                signal release from synapse 206
                  neurotransmitter secretion 206
                    synaptic vesicle exocytosis 154
                      calcium ion-regulated exocytosis of neurotransmitter 22
                        fast, calcium ion-dependent exocytosis of neurotransmitter 1
paths to the root