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ONTOLOGY REPORT - ANNOTATIONS

Term:neuroendocrine cell differentiation
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Accession:GO:0061101 term browser browse the term
Definition:The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.

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neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10952889) MGI
Ensembl		 PMID:10952889 GO_REF:0000107 NCBI chr11:98,182,213...98,185,057
Ensembl chr11:98,182,787...98,183,506 		JBrowse link
G BCCIP BRCA2 and CDKN1A interacting protein involved_in ISO (PMID:18440304) UniProt PMID:18440304 NCBI chr 9:118,450,788...118,479,521
Ensembl chr 9:118,450,789...118,470,697 		JBrowse link
G GATA2 GATA binding protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16543408) MGI
Ensembl		 PMID:16543408 GO_REF:0000107 NCBI chr22:52,549,112...52,562,911
Ensembl chr22:52,555,738...52,562,909 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:10952889) Ensembl
MGI		 PMID:10952889 GO_REF:0000107 NCBI chr15:88,220,093...88,222,563
Ensembl chr15:88,220,083...88,223,243 		JBrowse link
G JAG1 jagged canonical Notch ligand 1 acts_upstream_of ISO (PMID:15064243) MGI PMID:15064243 NCBI chr 2:27,484,699...27,521,108
Ensembl chr 2:27,484,760...27,522,504 		JBrowse link
G NKX2-2 NK2 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18987169) Ensembl
MGI		 PMID:18987169 GO_REF:0000107 NCBI chr 2:50,499,802...50,511,309
Ensembl chr 2:50,500,691...50,502,438 		JBrowse link
G NKX6-3 NK6 homeobox 3 acts_upstream_of_or_within ISO (PMID:18347062) MGI PMID:18347062 NCBI chr 8:39,620,972...39,627,298
Ensembl chr 8:39,620,990...39,625,052 		JBrowse link
G NOTCH1 notch receptor 1 acts_upstream_of
involved_in		 ISO
IEA		 (PMID:15064243) MGI
Ensembl		 PMID:15064243 GO_REF:0000107 NCBI chr12:1,656,815...1,707,566
Ensembl chr12:1,656,918...1,709,585 		JBrowse link
G OTP orthopedia homeobox acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:10557207) MGI
Ensembl		 PMID:10557207 GO_REF:0000107 NCBI chr 4:71,861,857...71,877,994
Ensembl chr 4:71,863,413...71,871,769 		JBrowse link
G POU3F2 POU class 3 homeobox 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:8543156) Ensembl
MGI		 PMID:8543156 GO_REF:0000107 NCBI chr13:75,027,360...75,032,222
Ensembl chr13:75,030,677...75,032,008 		JBrowse link
G WNT11 Wnt family member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:67,393,975...67,427,247
Ensembl chr 1:67,399,074...67,418,509 		JBrowse link
adrenal chromaffin cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:12361965) MGI
Ensembl		 PMID:12361965 GO_REF:0000107 NCBI chr11:98,182,213...98,185,057
Ensembl chr11:98,182,787...98,183,506 		JBrowse link
G INSM1 INSM transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:49,360,307...49,363,136
Ensembl chr 2:49,360,448...49,361,992 		JBrowse link
carotid body glomus cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:15878769) MGI
Ensembl		 PMID:15878769 GO_REF:0000107 NCBI chr11:98,182,213...98,185,057
Ensembl chr11:98,182,787...98,183,506 		JBrowse link
lung neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9126746) MGI
Ensembl		 PMID:9126746 GO_REF:0000107 NCBI chr11:98,182,213...98,185,057
Ensembl chr11:98,182,787...98,183,506 		JBrowse link
negative regulation of stomach neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18173746) Ensembl
MGI		 PMID:18173746 GO_REF:0000107 NCBI chr15:88,220,093...88,222,563
Ensembl chr15:88,220,083...88,223,243 		JBrowse link
G NKX6-3 NK6 homeobox 3 acts_upstream_of_or_within ISO (PMID:18347062) MGI PMID:18347062 NCBI chr 8:39,620,972...39,627,298
Ensembl chr 8:39,620,990...39,625,052 		JBrowse link
pancreatic D cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ONECUT1 one cut homeobox 1 acts_upstream_of_or_within ISO (PMID:10825208) MGI PMID:10825208 NCBI chr26:30,609,392...30,645,996 JBrowse link
G ONECUT1 one cut homeobox 1 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr26:30,610,161...30,643,380 JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:56,889,160...56,948,304
Ensembl chr13:56,889,780...56,946,413 		JBrowse link
stomach neuroendocrine cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASCL1 achaete-scute family bHLH transcription factor 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:18173746) MGI
Ensembl		 PMID:18173746 GO_REF:0000107 NCBI chr11:98,182,213...98,185,057
Ensembl chr11:98,182,787...98,183,506 		JBrowse link
G HES1 hes family bHLH transcription factor 1 involved_in
acts_upstream_of		 IEA
ISO		 (PMID:18173746) Ensembl
MGI		 PMID:18173746 GO_REF:0000107 NCBI chr15:88,220,093...88,222,563
Ensembl chr15:88,220,083...88,223,243 		JBrowse link
G NKX6-3 NK6 homeobox 3 acts_upstream_of ISO (PMID:18347062) MGI PMID:18347062 NCBI chr 8:39,620,972...39,627,298
Ensembl chr 8:39,620,990...39,625,052 		JBrowse link
thyroid-stimulating hormone-secreting cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMP2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9463347) Ensembl
MGI		 PMID:9463347 GO_REF:0000107 NCBI chr 2:31,349,394...31,361,227
Ensembl chr 2:31,348,808...31,360,901 		JBrowse link
G FGF2 fibroblast growth factor 2 acts_upstream_of_or_within ISO (PMID:9463347) MGI PMID:9463347 NCBI chr 7:70,089,394...70,157,423 JBrowse link
G FGF8 fibroblast growth factor 8 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9463347) Ensembl
MGI		 PMID:9463347 GO_REF:0000107 NCBI chr 9:94,797,157...94,803,725
Ensembl chr 9:94,798,088...94,803,629 		JBrowse link
G GATA2 GATA binding protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:16543408) MGI
Ensembl		 PMID:16543408 GO_REF:0000107 NCBI chr22:52,549,112...52,562,911
Ensembl chr22:52,555,738...52,562,909 		JBrowse link
G LHX3 LIM homeobox 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:8638120) MGI
Ensembl		 PMID:8638120 GO_REF:0000107 NCBI chr12:1,997,437...2,007,473
Ensembl chr12:2,000,638...2,006,430 		JBrowse link
G WNT4 Wnt family member 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18351662) Ensembl
MGI		 PMID:18351662 GO_REF:0000107 NCBI chr20:110,517,391...110,543,802
Ensembl chr20:110,517,564...110,541,203 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19829
    cellular process 19347
      cellular developmental process 4596
        cell differentiation 4595
          neuron differentiation 1709
            neuroendocrine cell differentiation 20
              adrenal chromaffin cell differentiation 2
              carotid body glomus cell differentiation 1
              lung neuroendocrine cell differentiation 1
              neuroendocrine cell differentiation involved in prostate gland acinus development 0
              pancreatic D cell differentiation + 3
              stomach neuroendocrine cell differentiation + 3
              thyroid-stimulating hormone-secreting cell differentiation + 6
Path 2
Term Annotations click to browse term
  biological_process 19829
    developmental process 6858
      anatomical structure development 6432
        multicellular organism development 5173
          system development 4482
            nervous system development 2806
              neurogenesis 2070
                generation of neurons 1793
                  neuron differentiation 1709
                    neuroendocrine cell differentiation 20
                      adrenal chromaffin cell differentiation 2
                      carotid body glomus cell differentiation 1
                      lung neuroendocrine cell differentiation 1
                      neuroendocrine cell differentiation involved in prostate gland acinus development 0
                      pancreatic D cell differentiation + 3
                      stomach neuroendocrine cell differentiation + 3
                      thyroid-stimulating hormone-secreting cell differentiation + 6
paths to the root