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ONTOLOGY REPORT - ANNOTATIONS

Term:protein homotetramerization
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Accession:GO:0051289 term browser browse the term
Definition:The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
Synonyms:exact_synonym: protein homotetramer assembly;   protein homotetramer biosynthesis;   protein homotetramer biosynthetic process;   protein homotetramer formation

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protein homotetramerization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acaca acetyl-CoA carboxylase alpha involved_in ISO (MGI:4840155|PMID:20952656) UniProt PMID:20952656 MGI:4840155 NCBI chrNW_004624871:4,103,014...4,364,690
Ensembl chrNW_004624871:4,105,067...4,412,325 		JBrowse link
G Acacb acetyl-CoA carboxylase beta involved_in ISO (PMID:20952656) UniProt PMID:20952656 NCBI chrNW_004624747:12,287,817...12,426,340
Ensembl chrNW_004624747:12,307,541...12,424,897 		JBrowse link
G Acot13 acyl-CoA thioesterase 13 involved_in ISO (PMID:16934754), (PMID:19170545) UniProt PMID:16934754 PMID:19170545 NCBI chrNW_004624756:2,350,671...2,363,475 JBrowse link
G Aldh1a2 aldehyde dehydrogenase 1 family member A2 involved_in ISO (PMID:29240402) UniProt PMID:29240402 NCBI chrNW_004624781:13,756,469...13,845,253
Ensembl chrNW_004624781:13,756,390...13,845,479 		JBrowse link
G Aldh1a3 aldehyde dehydrogenase 1 family member A3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624768:3,851,361...3,885,609
Ensembl chrNW_004624768:3,851,257...3,885,609 		JBrowse link
G Aldh9a1 aldehyde dehydrogenase 9 family member A1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624826:3,994,188...4,026,437
Ensembl chrNW_004624826:3,994,183...4,026,696 		JBrowse link
G Apip APAF1 interacting protein involved_in ISO (PMID:24367089) UniProt PMID:24367089 NCBI chrNW_004624767:12,257,591...12,285,968
Ensembl chrNW_004624767:12,257,597...12,280,154 		JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (PMID:23055524) UniProt PMID:23055524 NCBI chrNW_004624750:3,789,015...3,827,079
Ensembl chrNW_004624750:3,789,022...3,827,079 		JBrowse link
G Aqp10 aquaporin 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624885:3,014,853...3,032,920
Ensembl chrNW_004624885:3,014,351...3,022,248 		JBrowse link
G Aqp2 aquaporin 2 involved_in ISO (PMID:24733887) UniProt PMID:24733887 NCBI chrNW_004624816:2,332,477...2,340,797
Ensembl chrNW_004624816:2,335,471...2,340,828 		JBrowse link
G Aqp4 aquaporin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624770:5,581,192...5,593,470
Ensembl chrNW_004624770:5,580,808...5,594,628 		JBrowse link
G Aqp5 aquaporin 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624816:2,326,059...2,329,525
Ensembl chrNW_004624816:2,326,010...2,329,544 		JBrowse link
G B2m beta-2-microglobulin involved_in ISO (PMID:28468825) ARUK-UCL PMID:28468825 NCBI chrNW_004624804:11,514,728...11,521,625 JBrowse link
G Cbr4 carbonyl reductase 4 involved_in ISO (PMID:19000905) UniProt PMID:19000905 NCBI chrNW_004624769:564,148...603,402
Ensembl chrNW_004624769:581,800...604,075 		JBrowse link
G Cby1 chibby 1, beta catenin antagonist involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624752:9,467,636...9,485,085
Ensembl chrNW_004624752:9,469,766...9,485,175 		JBrowse link
G Crtc2 CREB regulated transcription coactivator 2 involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624885:3,265,079...3,276,594
Ensembl chrNW_004624885:3,264,983...3,277,459 		JBrowse link
G Cryz crystallin zeta involved_in ISO (PMID:17497241) UniProt PMID:17497241 NCBI chrNW_004624742:21,951,389...21,974,134
Ensembl chrNW_004624742:21,955,368...21,990,402 		JBrowse link
G Cth cystathionine gamma-lyase involved_in ISO (PMID:19019829) UniProt PMID:19019829 NCBI chrNW_004624742:25,619,261...25,642,477
Ensembl chrNW_004624742:25,619,277...25,642,875 		JBrowse link
G Dnm1 dynamin 1 involved_in ISO (PMID:9362482) UniProt PMID:9362482 NCBI chrNW_004624760:6,605,902...6,646,575
Ensembl chrNW_004624760:6,604,787...6,646,622 		JBrowse link
G Gbp5 guanylate binding protein 5 involved_in ISO (PMID:22461501) UniProt PMID:22461501 NCBI chrNW_004624742:8,324,902...8,335,965 JBrowse link
G Gls glutaminase involved_in ISO (MGI:5320252|PMID:22228304)
(PMID:22049910)		 UniProt PMID:22049910 PMID:22228304 MGI:5320252 NCBI chrNW_004624854:5,106,419...5,202,445
Ensembl chrNW_004624854:5,108,566...5,202,240 		JBrowse link
G Golga2 golgin A2 involved_in ISO PMID:25787021 UniProt PMID:25787021 RGD:10400873 NCBI chrNW_004624760:6,588,351...6,605,518 JBrowse link
G Gria3 glutamate ionotropic receptor AMPA type subunit 3 involved_in ISO (PMID:17989220) UniProt PMID:17989220 NCBI chrNW_004624797:1,775,105...2,167,651
Ensembl chrNW_004624797:1,775,071...2,169,286 		JBrowse link
G Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 involved_in ISO (PMID:28086084) UniProt PMID:28086084 NCBI chrNW_004624759:9,636,380...10,044,832
Ensembl chrNW_004624759:9,636,457...10,049,403 		JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 involved_in ISO (PMID:15990111) UniProt PMID:15990111 NCBI chrNW_004624797:14,148,580...14,184,471 JBrowse link
G Hsd17b10 hydroxysteroid 17-beta dehydrogenase 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624909:681,731...684,130
Ensembl chrNW_004624909:681,731...684,237 		JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor type 1 involved_in ISO PMID:36376291 UniProt PMID:36376291 RGD:405650379 NCBI chrNW_004624773:14,856,803...15,193,173
Ensembl chrNW_004624773:14,856,804...15,193,168 		JBrowse link
G Itpr3 inositol 1,4,5-trisphosphate receptor type 3 involved_in ISO (PMID:37898605) UniProt PMID:37898605 NCBI chrNW_004624754:23,228,690...23,281,552
Ensembl chrNW_004624754:23,229,281...23,281,621 		JBrowse link
G Kcnj12 potassium inwardly rectifying channel subfamily J member 12 involved_in ISO (PMID:21874019) UniProt PMID:21874019 NCBI chrNW_004624849:5,092,750...5,132,246 JBrowse link
G Kcnj2 potassium inwardly rectifying channel subfamily J member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624801:365,393...375,802
Ensembl chrNW_004624801:365,361...374,487 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 involved_in ISO (PMID:29724949) UniProt PMID:29724949 NCBI chrNW_004624907:1,266,348...1,279,258
Ensembl chrNW_004624907:1,266,348...1,278,699 		JBrowse link
G LOC101697457 glycine N-methyltransferase involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624754:16,522,771...16,525,292
Ensembl chrNW_004624754:16,520,823...16,525,512 		JBrowse link
G Mat1a methionine adenosyltransferase 1A involved_in ISO (PMID:23425511) UniProt PMID:23425511 NCBI chrNW_004624841:6,843,725...6,864,700
Ensembl chrNW_004624841:6,843,741...6,862,683 		JBrowse link
G Mcoln1 mucolipin TRP cation channel 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624828:634,318...643,406
Ensembl chrNW_004624828:634,214...643,633 		JBrowse link
G Me1 malic enzyme 1 involved_in ISO (PMID:7757881) UniProt PMID:7757881 NCBI chrNW_004624799:11,166,398...11,382,662 JBrowse link
G Mip major intrinsic protein of lens fiber involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624802:11,600,405...11,603,502
Ensembl chrNW_004624802:11,600,405...11,603,502 		JBrowse link
G Osbpl2 oxysterol binding protein like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624741:28,099,384...28,145,179
Ensembl chrNW_004624741:28,116,827...28,144,263 		JBrowse link
G Pkd2 polycystin 2, transient receptor potential cation channel involved_in ISO (PMID:28092368) UniProt PMID:28092368 NCBI chrNW_004624872:4,539,965...4,592,004
Ensembl chrNW_004624872:4,539,847...4,594,793 		JBrowse link
G Pkd2l1 polycystin 2 like 1, transient receptor potential cation channel involved_in ISO (PMID:30004384) UniProt PMID:30004384 NCBI chrNW_004624737:12,097,134...12,137,574
Ensembl chrNW_004624737:12,102,976...12,137,737 		JBrowse link
G Pkm pyruvate kinase M1/2 ISO RGD PMID:10734049 RGD:151708737 NCBI chrNW_004624781:1,796,909...1,823,787
Ensembl chrNW_004624781:1,796,801...1,824,144 		JBrowse link
G Samhd1 SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 involved_in ISO (MGI:6114841|PMID:29379009)
(PMID:23601106), (PMID:24217394), (PMID:26294762)		 UniProt PMID:23601106 PMID:24217394 PMID:26294762 PMID:29379009 MGI:6114841 NCBI chrNW_004624842:2,591,016...2,649,746
Ensembl chrNW_004624842:2,591,148...2,647,742 		JBrowse link
G Shmt1 serine hydroxymethyltransferase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624849:3,108,875...3,146,669
Ensembl chrNW_004624849:3,114,876...3,146,248 		JBrowse link
G Shmt2 serine hydroxymethyltransferase 2 involved_in ISO (PMID:29180469) UniProt PMID:29180469 NCBI chrNW_004624802:10,713,276...10,718,391
Ensembl chrNW_004624802:10,713,276...10,719,253 		JBrowse link
G Sod2 superoxide dismutase 2 involved_in ISO (PMID:19265433) UniProt PMID:19265433 NCBI chrNW_004624855:3,260,800...3,271,864
Ensembl chrNW_004624855:3,260,809...3,271,367 		JBrowse link
G Ssbp1 single stranded DNA binding protein 1 involved_in ISO (PMID:31550240) UniProt PMID:31550240 NCBI chrNW_004624765:21,746,633...21,771,234
Ensembl chrNW_004624765:21,746,794...21,761,258 		JBrowse link
G Sycp1 synaptonemal complex protein 1 involved_in ISO (PMID:29915389) UniProt PMID:29915389 NCBI chrNW_004624772:10,524,656...10,699,894
Ensembl chrNW_004624772:10,525,203...10,699,560 		JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624848:2,380,827...2,395,807
Ensembl chrNW_004624848:2,380,670...2,396,314 		JBrowse link
G Thg1l tRNA-histidine guanylyltransferase 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624733:31,732,247...31,739,150
Ensembl chrNW_004624733:31,730,882...31,739,377 		JBrowse link
G Tk1 thymidine kinase 1 involved_in ISO (PMID:17407781)
(PMID:14697231)		 UniProt PMID:14697231 PMID:17407781 NCBI chrNW_004624801:7,685,003...7,692,949
Ensembl chrNW_004624801:7,685,017...7,692,872 		JBrowse link
G Trpa1 transient receptor potential cation channel subfamily A member 1 involved_in ISO (PMID:25855297) UniProt PMID:25855297 NCBI chrNW_004624744:18,997,273...19,042,838
Ensembl chrNW_004624744:18,997,462...19,042,227 		JBrowse link
G Trpm2 transient receptor potential cation channel subfamily M member 2 involved_in ISO (PMID:30467180) UniProt PMID:30467180 NCBI chrNW_004624745:29,757,267...29,809,607
Ensembl chrNW_004624745:29,757,106...29,806,795 		JBrowse link
G Trpm4 transient receptor potential cation channel subfamily M member 4 involved_in ISO (MGI:6119829|PMID:29211714)
(PMID:29211723), (PMID:29217581)		 UniProt PMID:29211714 PMID:29211723 PMID:29217581 MGI:6119829 NCBI chrNW_004624832:4,902,335...4,937,806
Ensembl chrNW_004624832:4,902,659...4,936,926 		JBrowse link
G Trpv1 transient receptor potential cation channel subfamily V member 1 involved_in ISO PMID:27281200 UniProt PMID:27281200 RGD:11344330 NCBI chrNW_004624786:6,231,494...6,249,001
Ensembl chrNW_004624786:6,231,494...6,249,001 		JBrowse link
G Trpv6 transient receptor potential cation channel subfamily V member 6 involved_in ISO PMID:27296226 UniProt PMID:27296226 RGD:11344952 NCBI chrNW_004624800:12,074,997...12,090,141
Ensembl chrNW_004624800:12,074,999...12,090,049 		JBrowse link
G Upb1 beta-ureidopropionase 1 involved_in ISO (PMID:29976570) UniProt PMID:29976570 NCBI chrNW_004624747:9,911,323...9,940,770
Ensembl chrNW_004624747:9,911,448...9,940,537 		JBrowse link
G Usp16 ubiquitin specific peptidase 16 involved_in IEA UniProt GO_REF:0000104 NCBI chrNW_004624745:17,005,020...17,029,220
Ensembl chrNW_004624745:17,006,175...17,028,952 		JBrowse link
G Vasp vasodilator stimulated phosphoprotein involved_in IEA InterPro GO_REF:0000002 NCBI chrNW_004624832:7,619,211...7,631,576
Ensembl chrNW_004624832:7,619,134...7,630,943 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15052
    cellular process 14191
      cellular component organization or biogenesis 6194
        cellular component organization 6004
          cellular component assembly 2861
            protein-containing complex assembly 1425
              protein complex oligomerization 247
                protein homooligomerization 176
                  protein homotetramerization 57
                    negative regulation of protein homotetramerization 0
                    positive regulation of protein homotetramerization 0
                    regulation of protein homotetramerization + 0
paths to the root