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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of isotype switching to IgE isotypes
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Accession:GO:0048294 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.
Synonyms:exact_synonym: down regulation of isotype switching to IgE isotypes;   downregulation of isotype switching to IgE isotypes;   negative regulation of class switch recombination to IgE isotypes;   negative regulation of class switching to IgE isotypes;   negative regulation of isotype switch recombination to IgE isotypes
 narrow_synonym: inhibition of isotype switching to IgE isotypes


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negative regulation of isotype switching to IgE isotypes term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 B cell leukemia/lymphoma 6 acts_upstream_of_or_within IMP
IGI		 (PMID:10490661) MGI PMID:10490661 NCBI chr16:23,780,058...23,807,602
Ensembl chr16:23,783,802...23,807,602 		JBrowse link
G Foxp3 forkhead box P3 acts_upstream_of_or_within IMP (PMID:16275384) MGI PMID:16275384 NCBI chr  X:7,445,915...7,461,482
Ensembl chr  X:7,439,883...7,461,484 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 acts_upstream_of_or_within IMP (PMID:17137798) MGI PMID:17137798 NCBI chr18:38,551,960...38,598,250
Ensembl chr18:38,543,449...38,598,356 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28635
    developmental process 7493
      negative regulation of developmental process 1168
        negative regulation of isotype switching 4
          negative regulation of isotype switching to IgE isotypes 3
Path 2
Term Annotations click to browse term
  biological_process 28635
    cellular process 18392
      metabolic process 11624
        primary metabolic process 10232
          nucleobase-containing compound metabolic process 5757
            nucleic acid metabolic process 5155
              DNA metabolic process 1001
                DNA recombination 345
                  somatic cell DNA recombination 82
                    somatic diversification of immune receptors via germline recombination within a single locus 82
                      somatic recombination of immunoglobulin gene segments 70
                        somatic recombination of immunoglobulin genes involved in immune response 61
                          isotype switching 61
                            regulation of isotype switching 41
                              negative regulation of isotype switching 4
                                negative regulation of isotype switching to IgE isotypes 3
paths to the root