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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of T-helper 2 cell differentiation
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Accession:GO:0045629 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: down regulation of T-helper 2 cell differentiation;   downregulation of T-helper 2 cell differentiation
 narrow_synonym: inhibition of T-helper 2 cell differentiation
 related_synonym: negative regulation of T-helper 2 cell development



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negative regulation of T-helper 2 cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ANXA1 annexin A1 involved_in IDA
IEA
(PMID:17008549) UniProt
TreeGrafter
PMID:17008549 GO_REF:0000118 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,393
JBrowse link
G ASCL2 achaete-scute family bHLH transcription factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:2,268,498...2,270,588
Ensembl chr11:2,268,498...2,270,588
JBrowse link
G BCL6 BCL6 transcription repressor involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:12594267) Ensembl
MGI
PMID:12594267 GO_REF:0000107 NCBI chr 3:187,721,377...187,745,468
Ensembl chr 3:187,721,377...187,745,725
JBrowse link
G HLX H2.0 like homeobox involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:16424184) Ensembl
MGI
PMID:16424184 GO_REF:0000107 NCBI chr 1:220,879,443...220,885,059
Ensembl chr 1:220,879,431...220,885,059
JBrowse link
G SOCS5 suppressor of cytokine signaling 5 involved_in IEA
ISS
Ensembl
UniProt
GO_REF:0000024 GO_REF:0000107 NCBI chr 2:46,698,937...46,763,129
Ensembl chr 2:46,698,952...46,780,245
JBrowse link
G ZNF271P zinc finger protein 271, pseudogene acts_upstream_of_or_within ISO (PMID:19783676) MGI PMID:19783676 NCBI chr18:35,290,272...35,310,766
Ensembl chr18:35,290,276...35,328,390
Ensembl chr18:35,290,276...35,328,390
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19613
    immune system process 3224
      immune response 2288
        type 2 immune response 46
          negative regulation of type 2 immune response 16
            negative regulation of T-helper 2 cell differentiation 6
Path 2
Term Annotations click to browse term
  biological_process 19613
    cellular process 18246
      cellular developmental process 5172
        cell differentiation 5171
          cell development 3453
            hemopoiesis 1167
              leukocyte differentiation 749
                mononuclear cell differentiation 620
                  lymphocyte differentiation 513
                    T cell differentiation 365
                      T cell differentiation involved in immune response 98
                        alpha-beta T cell differentiation involved in immune response 90
                          CD4-positive, alpha-beta T cell differentiation involved in immune response 89
                            T-helper cell differentiation 87
                              regulation of T-helper cell differentiation 54
                                negative regulation of T-helper cell differentiation 21
                                  negative regulation of T-helper 2 cell differentiation 6
paths to the root