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ONTOLOGY REPORT - ANNOTATIONS

Term:thymic T cell selection
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Accession:GO:0045061 term browser browse the term
Definition:The process of T cell selection that occurs in the thymus.
Synonyms:exact_synonym: thymic T lymphocyte selection

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thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card11 caspase recruitment domain family member 11 acts_upstream_of_or_within ISO (PMID:12867038) MGI PMID:12867038 NCBI chrNW_004955460:12,368,987...12,487,675
Ensembl chrNW_004955460:12,368,918...12,490,041 		JBrowse link
G Gata3 GATA binding protein 3 acts_upstream_of_or_within ISO (PMID:14670303) MGI PMID:14670303 NCBI chrNW_004955421:24,448,446...24,477,885
Ensembl chrNW_004955421:24,457,496...24,478,744 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B acts_upstream_of_or_within ISO (PMID:14517551) MGI PMID:14517551 NCBI chrNW_004955489:726,641...814,180
Ensembl chrNW_004955489:725,759...814,180 		JBrowse link
G Jag2 jagged canonical Notch ligand 2 involved_in ISO (PMID:10383933) UniProt PMID:10383933 NCBI chrNW_004955538:3,421,685...3,433,829
Ensembl chrNW_004955538:3,421,685...3,433,842 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase 70kDa acts_upstream_of_or_within ISO (PMID:9208839) MGI PMID:9208839 NCBI chrNW_004955470:4,379,260...4,397,851
Ensembl chrNW_004955470:4,386,311...4,396,419 		JBrowse link
negative regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptpn2 protein tyrosine phosphatase non-receptor type 2 involved_in ISO (PMID:22080863) UniProt PMID:22080863 NCBI chrNW_004955402:771,410...846,671 JBrowse link
negative thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aire autoimmune regulator acts_upstream_of_or_within ISO (PMID:23382543) MGI PMID:23382543 NCBI chrNW_004955407:41,157,503...41,165,032
Ensembl chrNW_004955407:41,157,484...41,165,014 		JBrowse link
G Atg5 autophagy related 5 acts_upstream_of_or_within ISO (PMID:23382543) MGI PMID:23382543 NCBI chrNW_004955411:31,501,191...31,646,407
Ensembl chrNW_004955411:31,522,420...31,646,827 		JBrowse link
G Ccr7 C-C motif chemokine receptor 7 involved_in ISO (PMID:17785582) BHF-UCL PMID:17785582 NCBI chrNW_004955451:15,086,119...15,101,862
Ensembl chrNW_004955451:15,086,119...15,095,561 		JBrowse link
G Cd28 CD28 molecule acts_upstream_of_or_within ISO (PMID:10429671) MGI PMID:10429671 NCBI chrNW_004955457:11,159,769...11,253,099
Ensembl chrNW_004955457:11,162,282...11,192,991 		JBrowse link
G Cd3e CD3e molecule acts_upstream_of_or_within ISO (PMID:7630421) MGI PMID:7630421 NCBI chrNW_004955412:19,464,666...19,476,425
Ensembl chrNW_004955412:19,464,613...19,478,990 		JBrowse link
G Cd74 CD74 molecule acts_upstream_of_or_within ISO (PMID:7679955) MGI PMID:7679955 NCBI chrNW_004955415:4,129,151...4,138,336
Ensembl chrNW_004955415:4,129,254...4,137,826 		JBrowse link
G Dock2 dedicator of cytokinesis 2 acts_upstream_of_or_within ISO (PMID:12871644) MGI PMID:12871644 NCBI chrNW_004955408:22,630,375...23,059,832
Ensembl chrNW_004955408:22,630,364...23,059,899 		JBrowse link
G Fas Fas cell surface death receptor acts_upstream_of_or_within ISO (PMID:10429671) MGI PMID:10429671 NCBI chrNW_004955425:3,961,671...3,987,513
Ensembl chrNW_004955425:3,961,013...3,987,455 		JBrowse link
G Gli3 GLI family zinc finger 3 involved_in ISO (PMID:19667090) BHF-UCL PMID:19667090 NCBI chrNW_004955460:1,528,457...1,805,584
Ensembl chrNW_004955460:1,528,412...1,805,918 		JBrowse link
G Mink1 misshapen like kinase 1 acts_upstream_of_or_within ISO (PMID:15608642) MGI PMID:15608642 NCBI chrNW_004955467:10,256,722...10,312,011
Ensembl chrNW_004955467:10,256,434...10,313,834 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:8666928) MGI PMID:8666928 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISO (PMID:17227833) BHF-UCL PMID:17227833 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Spn sialophorin acts_upstream_of_or_within ISO (PMID:10429671) MGI PMID:10429671 NCBI chrNW_004955493:7,256,505...7,258,607 JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase 70kDa acts_upstream_of_or_within ISO (PMID:7630421) MGI PMID:7630421 NCBI chrNW_004955470:4,379,260...4,397,851
Ensembl chrNW_004955470:4,386,311...4,396,419 		JBrowse link
positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd3d CD3d molecule involved_in ISO (PMID:9135151) UniProt PMID:9135151 NCBI chrNW_004955412:19,481,059...19,484,890
Ensembl chrNW_004955412:19,480,977...19,484,721 		JBrowse link
G Cd74 CD74 molecule acts_upstream_of_or_within ISO (PMID:7679955), (PMID:8598040)
(PMID:9432982)		 MGI PMID:7679955 PMID:8598040 PMID:9432982 NCBI chrNW_004955415:4,129,151...4,138,336
Ensembl chrNW_004955415:4,129,254...4,137,826 		JBrowse link
G Dock2 dedicator of cytokinesis 2 acts_upstream_of_or_within ISO (PMID:12871644) MGI PMID:12871644 NCBI chrNW_004955408:22,630,375...23,059,832
Ensembl chrNW_004955408:22,630,364...23,059,899 		JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B acts_upstream_of_or_within ISO (PMID:15064401) MGI PMID:15064401 NCBI chrNW_004955489:726,641...814,180
Ensembl chrNW_004955489:725,759...814,180 		JBrowse link
G LOC102023843 HLA class II histocompatibility antigen, DM alpha chain acts_upstream_of_or_within ISO (PMID:8598040)
(PMID:8598041), (PMID:9432982)
(PMID:8638109)		 MGI PMID:8598040 PMID:8598041 PMID:8638109 PMID:9432982 NCBI chrNW_004955437:1,558,806...1,562,294
Ensembl chrNW_004955437:1,558,911...1,562,162 		JBrowse link
G Nfatc3 nuclear factor of activated T cells 3 involved_in ISO (PMID:17579027) UniProt PMID:17579027 NCBI chrNW_004955484:8,433,765...8,558,005
Ensembl chrNW_004955484:8,436,330...8,526,680 		JBrowse link
G Ptprc protein tyrosine phosphatase receptor type C acts_upstream_of_or_within ISO (PMID:8666928) MGI PMID:8666928 NCBI chrNW_004955406:35,005,577...35,127,395
Ensembl chrNW_004955406:35,005,214...35,129,552 		JBrowse link
G Shh sonic hedgehog signaling molecule involved_in ISO (PMID:17227833) BHF-UCL PMID:17227833 NCBI chrNW_004955491:8,647,133...8,657,381 JBrowse link
G Srf serum response factor acts_upstream_of_or_within ISO (PMID:21098124) MGI PMID:21098124 NCBI chrNW_004955437:9,100,546...9,109,305
Ensembl chrNW_004955437:9,098,968...9,107,057 		JBrowse link
G Stk11 serine/threonine kinase 11 acts_upstream_of_or_within ISO (PMID:21487392) MGI PMID:21487392 NCBI chrNW_004955495:6,678,195...6,699,408
Ensembl chrNW_004955495:6,678,195...6,699,058 		JBrowse link
G Zap70 zeta-chain (TCR) associated protein kinase 70kDa acts_upstream_of_or_within ISO (PMID:7630421) MGI PMID:7630421 NCBI chrNW_004955470:4,379,260...4,397,851
Ensembl chrNW_004955470:4,386,311...4,396,419 		JBrowse link
regulation of positive thymic T cell selection term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Foxn1 forkhead box N1 involved_in ISO (PMID:24184560) UniProt PMID:24184560 NCBI chrNW_004955481:4,611,246...4,640,606
Ensembl chrNW_004955481:4,611,087...4,627,113 		JBrowse link
G Tox thymocyte selection associated high mobility group box involved_in ISO (PMID:18195075) UniProt PMID:18195075 NCBI chrNW_004955444:19,453,789...19,796,419
Ensembl chrNW_004955444:19,453,783...19,795,167 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12572
    immune system process 2029
      T cell selection 57
        thymic T cell selection 26
          negative thymic T cell selection 14
          positive thymic T cell selection + 14
Path 2
Term Annotations click to browse term
  biological_process 12572
    developmental process 5945
      cellular developmental process 3949
        cell differentiation 3948
          cell development 2894
            hemopoiesis 942
              leukocyte differentiation 608
                mononuclear cell differentiation 493
                  lymphocyte differentiation 400
                    T cell differentiation 299
                      T cell differentiation in thymus 101
                        thymic T cell selection 26
                          negative thymic T cell selection 14
                          positive thymic T cell selection + 14
paths to the root