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ONTOLOGY REPORT - ANNOTATIONS

Term:response to L-leucine
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Accession:GO:0043201 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-leucine stimulus.
Synonyms:broad_synonym: response to leucine

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show annotations for term's descendants           Sort by:
response to L-leucine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdx1 pancreatic and duodenal homeobox 1 ISO RGD PMID:19438972 RGD:2311161 NCBI chrNW_004955497:7,281,886...7,307,969 JBrowse link
G Pik3c3 phosphatidylinositol 3-kinase catalytic subunit type 3 ISO RGD PMID:19015198 RGD:2303128 NCBI chrNW_004955402:28,081,150...28,195,305
Ensembl chrNW_004955402:28,081,098...28,196,252 		JBrowse link
G Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha ISO RGD PMID:24124592 RGD:10045951 NCBI chrNW_004955420:8,355,415...8,427,024
Ensembl chrNW_004955420:8,356,353...8,427,024 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO RGD PMID:22612562 RGD:7242173 NCBI chrNW_004955480:543,397...1,188,376
Ensembl chrNW_004955480:1,078,322...1,188,435 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 ISO RGD PMID:16616211 RGD:1643098 NCBI chrNW_004955451:3,181,085...3,225,610 JBrowse link
cellular response to L-leucine term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ep300 E1A binding protein p300 involved_in ISO (PMID:30197302), (PMID:32561715) UniProt PMID:30197302 PMID:32561715 NCBI chrNW_004955413:26,647,553...26,727,875
Ensembl chrNW_004955413:26,648,339...26,727,933 		JBrowse link
G Hnf1a HNF1 homeobox A ISO RGD PMID:21874357 RGD:150540304 NCBI chrNW_004955455:10,694,102...10,717,613
Ensembl chrNW_004955455:10,694,102...10,717,613 		JBrowse link
G Klhl22 kelch like family member 22 involved_in ISO (PMID:29769719) UniProt PMID:29769719 NCBI chrNW_004955442:19,010,971...19,051,300
Ensembl chrNW_004955442:19,009,155...19,051,393 		JBrowse link
G Lars1 leucyl-tRNA synthetase 1 involved_in ISO (PMID:22424946) CAFA PMID:22424946 NCBI chrNW_004955415:7,923,292...7,983,757
Ensembl chrNW_004955415:7,923,059...7,983,757 		JBrowse link
G Mtor mechanistic target of rapamycin kinase involved_in ISO (PMID:22424946) CAFA PMID:22424946 NCBI chrNW_004955486:2,487,642...2,599,694
Ensembl chrNW_004955486:2,487,642...2,599,694 		JBrowse link
G Rptor regulatory associated protein of MTOR complex 1 involved_in ISO (PMID:22424946) CAFA PMID:22424946 NCBI chrNW_004955506:2,009,422...2,401,775
Ensembl chrNW_004955506:2,008,044...2,401,775 		JBrowse link
G Rragd Ras related GTP binding D involved_in ISO (PMID:22424946) CAFA PMID:22424946 NCBI chrNW_004955411:16,111,931...16,155,662
Ensembl chrNW_004955411:16,114,755...16,138,433 		JBrowse link
G Sesn2 sestrin 2 involved_in ISO (PMID:26586190)
(PMID:26449471)		 UniProt PMID:26449471 PMID:26586190 NCBI chrNW_004955452:7,392,644...7,417,204
Ensembl chrNW_004955452:7,393,007...7,417,304 		JBrowse link
G Stambpl1 STAM binding protein like 1 involved_in ISO (PMID:35114100) UniProt PMID:35114100 NCBI chrNW_004955425:4,045,789...4,091,942
Ensembl chrNW_004955425:4,045,725...4,092,019 		JBrowse link
G Ubr1 ubiquitin protein ligase E3 component n-recognin 1 involved_in ISO (PMID:20298436) UniProt PMID:20298436 NCBI chrNW_004955416:9,571,628...9,731,551
Ensembl chrNW_004955416:9,572,171...9,731,453 		JBrowse link
G Ubr2 ubiquitin protein ligase E3 component n-recognin 2 involved_in ISO (PMID:20298436) UniProt PMID:20298436 NCBI chrNW_004955437:8,678,212...8,780,700
Ensembl chrNW_004955437:8,677,801...8,782,120 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12507
    response to stimulus 6746
      response to chemical 3523
        response to nitrogen compound 1280
          response to L-leucine 16
            cellular response to L-leucine 11
Path 2
Term Annotations click to browse term
  biological_process 12507
    response to stimulus 6746
      response to chemical 3523
        response to acid chemical 220
          response to amino acid 202
            response to L-leucine 16
              cellular response to L-leucine 11
paths to the root