Rps6kb1 (ribosomal protein S6 kinase B1) - Rat Genome Database

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Gene: Rps6kb1 (ribosomal protein S6 kinase B1) Chinchilla lanigera
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Symbol: Rps6kb1
Name: ribosomal protein S6 kinase B1
RGD ID: 9022823
Description: ENCODES a protein that exhibits ATP binding (ortholog); identical protein binding (ortholog); PDZ domain binding (ortholog); INVOLVED IN aging (ortholog); behavioral fear response (ortholog); cell migration (ortholog); PARTICIPATES IN insulin signaling pathway; insulin-like growth factor signaling pathway; interleukin-4 signaling pathway; ASSOCIATED WITH Atrophy (ortholog); autosomal dominant polycystic kidney disease (ortholog); Burns (ortholog); FOUND IN cell surface (ortholog); cytoplasm (ortholog); cytosol (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: ribosomal protein S6 kinase beta-1; ribosomal protein S6 kinase, 70kDa, polypeptide 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554513,181,085 - 3,225,610 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
behavioral fear response  (ISO)
cell migration  (ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to growth factor stimulus  (ISO)
cellular response to hormone stimulus  (ISO)
cellular response to insulin stimulus  (ISO)
cellular response to interferon-gamma  (ISO)
cellular response to organic cyclic compound  (ISO)
G1/S transition of mitotic cell cycle  (ISO)
germ cell development  (ISO)
long-chain fatty acid import into cell  (ISO)
long-term memory  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of extrinsic apoptotic signaling pathway  (ISO)
negative regulation of insulin receptor signaling pathway  (ISO)
peptidyl-serine phosphorylation  (ISO)
positive regulation of mitotic cell cycle  (ISO)
positive regulation of skeletal muscle tissue growth  (ISO)
positive regulation of smooth muscle cell migration  (ISO)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of translation  (ISO)
positive regulation of translational initiation  (ISO)
protein kinase B signaling  (ISO)
protein phosphorylation  (ISO)
regulation of glucose import  (ISO)
response to amino acid  (ISO)
response to electrical stimulus involved in regulation of muscle adaptation  (ISO)
response to ethanol  (ISO)
response to glucagon  (ISO)
response to glucocorticoid  (ISO)
response to glucose  (ISO)
response to heat  (ISO)
response to insulin  (ISO)
response to leucine  (ISO)
response to lipopolysaccharide  (ISO)
response to mechanical stimulus  (ISO)
response to nutrient  (ISO)
response to nutrient levels  (ISO)
response to organic cyclic compound  (ISO)
response to organic substance  (ISO)
response to organonitrogen compound  (ISO)
response to peptide hormone  (ISO)
response to testosterone  (ISO)
response to toxic substance  (ISO)
response to tumor necrosis factor  (ISO)
response to wounding  (ISO)
response to xenobiotic stimulus  (ISO)
skeletal muscle atrophy  (ISO)
skeletal muscle contraction  (ISO)
TOR signaling  (ISO)

Cellular Component

References


Genomics

Comparative Map Data
Rps6kb1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554513,181,085 - 3,225,610 (-)NCBIChiLan1.0ChiLan1.0
RPS6KB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1759,893,046 - 59,950,574 (+)EnsemblGRCh38hg38GRCh38
GRCh381759,893,121 - 59,950,574 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371757,970,482 - 58,027,935 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361755,325,225 - 55,382,569 (+)NCBINCBI36hg18NCBI36
Build 341755,325,224 - 55,382,566NCBI
Celera1754,433,949 - 54,491,301 (+)NCBI
Cytogenetic Map17q23.1NCBI
HuRef1753,342,941 - 53,400,248 (+)NCBIHuRef
CHM1_11758,034,428 - 58,091,804 (+)NCBICHM1_1
Rps6kb1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391186,389,695 - 86,435,711 (-)NCBIGRCm39mm39
GRCm39 Ensembl1186,389,697 - 86,435,631 (-)Ensembl
GRCm381186,498,869 - 86,544,885 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1186,498,871 - 86,544,805 (-)EnsemblGRCm38mm10GRCm38
MGSCv371186,312,511 - 86,358,309 (-)NCBIGRCm37mm9NCBIm37
MGSCv361186,330,178 - 86,360,969 (-)NCBImm8
Celera1196,115,093 - 96,160,675 (-)NCBICelera
Cytogenetic Map11CNCBI
Rps6kb1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21071,323,777 - 71,367,908 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1071,323,777 - 71,367,908 (-)Ensembl
Rnor_6.01073,824,200 - 73,865,503 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1073,824,202 - 73,865,364 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01076,234,192 - 76,278,394 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41076,657,024 - 76,698,088 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11076,671,395 - 76,712,458 (-)NCBI
Celera1070,248,523 - 70,289,589 (-)NCBICelera
Cytogenetic Map10q26NCBI
RPS6KB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11758,798,930 - 58,856,480 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1758,799,069 - 58,853,653 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01753,958,807 - 54,014,752 (+)NCBIMhudiblu_PPA_v0panPan3
RPS6KB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1934,387,084 - 34,590,603 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl934,387,091 - 34,425,292 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha933,618,891 - 33,820,779 (+)NCBI
ROS_Cfam_1.0935,197,993 - 35,401,137 (+)NCBI
UMICH_Zoey_3.1933,981,681 - 34,184,055 (+)NCBI
UNSW_CanFamBas_1.0934,266,735 - 34,469,058 (+)NCBI
UU_Cfam_GSD_1.0934,353,112 - 34,555,827 (+)NCBI
Rps6kb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560233,582,174 - 33,634,004 (+)NCBI
SpeTri2.0NW_0049364903,441,046 - 3,492,917 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPS6KB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1236,111,653 - 36,160,376 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11236,111,584 - 36,159,287 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21237,386,770 - 37,434,407 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPS6KB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11633,498,098 - 33,556,553 (-)NCBI
ChlSab1.1 Ensembl1633,497,392 - 33,556,453 (-)Ensembl
Vero_WHO_p1.0NW_0236660774,283,812 - 4,342,844 (-)NCBI
Rps6kb1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248711,667,292 - 1,705,550 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: XM_005393978   ⟹   XP_005394035
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554513,181,085 - 3,225,610 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005393979   ⟹   XP_005394036
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554513,181,085 - 3,225,610 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013519164   ⟹   XP_013374618
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554513,185,000 - 3,225,610 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005394035 (Get FASTA)   NCBI Sequence Viewer  
  XP_005394036 (Get FASTA)   NCBI Sequence Viewer  
  XP_013374618 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005394035   ⟸   XM_005393978
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005394036   ⟸   XM_005393979
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013374618   ⟸   XM_013519164
- Peptide Label: isoform X3
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000013177 ENTREZGENE
Ensembl Protein ENSCLAP00000019232 ENTREZGENE
Ensembl Transcript ENSCLAT00000019418 ENTREZGENE
NCBI Gene Rps6kb1 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Rps6kb1  ribosomal protein S6 kinase B1    ribosomal protein S6 kinase, 70kDa, polypeptide 1  Symbol and/or name change 5135510 APPROVED