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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of MDA-5 signaling pathway
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Accession:GO:0039534 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the series of the MDA-5 signaling pathway.
Synonyms:exact_synonym: negative regulation of IFIH1 signaling pathway;   negative regulation of MDA-5 signalling pathway;   negative regulation of MDA5 signaling pathway;   negative regulation of melanoma differentiation-associated gene 5 signaling pathway


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negative regulation of MDA-5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C1qbp complement C1q binding protein involved_in ISO
ISS
IEA		 (PMID:19164550)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19164550 GO_REF:0000024 GO_REF:0000107 NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649 		JBrowse link
G Dhx58 DEXH-box helicase 58 involved_in ISO (PMID:21187438) RGD PMID:21187438 NCBI chr10:85,620,352...85,631,776
Ensembl chr10:85,620,357...85,631,525 		JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:25865883) RGD PMID:25865883 NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343 		JBrowse link
G Tkfc triokinase and FMN cyclase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:17600090)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:17600090 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:207,238,230...207,253,035
Ensembl chr 1:207,236,557...207,252,737 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    immune system process 2822
      negative regulation of immune system process 565
        negative regulation of cytoplasmic pattern recognition receptor signaling pathway 51
          negative regulation of MDA-5 signaling pathway 4
Path 2
Term Annotations click to browse term
  biological_process 19692
    response to stimulus 10511
      response to external stimulus 2701
        response to external biotic stimulus 1825
          response to other organism 1821
            defense response to other organism 1277
              defense response to symbiont 1142
                innate immune response 961
                  regulation of innate immune response 453
                    positive regulation of innate immune response 373
                      activation of innate immune response 302
                        innate immune response-activating signaling pathway 276
                          pattern recognition receptor signaling pathway 266
                            cytoplasmic pattern recognition receptor signaling pathway 169
                              regulation of cytoplasmic pattern recognition receptor signaling pathway 117
                                negative regulation of cytoplasmic pattern recognition receptor signaling pathway 51
                                  negative regulation of MDA-5 signaling pathway 4
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