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ONTOLOGY REPORT - ANNOTATIONS
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Term:
VEGF-activated neuropilin signaling pathway
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Accession:
GO:0038190
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Definition:
The series of molecular signals initiated by vascular endothelial growth factor (VEGF) binding to a neuropilin protein on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:
narrow_synonym:
VEGF-Npn-1 signaling
related_synonym:
vascular endothelial growth factor-activated neuropilin signaling pathway
only_in_taxon:
NCBITaxon:7742 ! Vertebrata
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Genes (2)
VEGF-activated neuropilin signaling pathway
Symbol
Object Name
Qualifiers
Evidence
Notes
Source
PubMed Reference(s)
RGD Reference(s)
Position
G
NRP1
neuropilin 1
involved_in
IEA
Ensembl
GO_REF:0000107
NCBI chr10:33,298,918...33,456,466
Ensembl chr10:33,883,173...34,039,648
G
VEGFA
vascular endothelial growth factor A
involved_in
ISO
(PMID:24863063)
(PMID:21658587)
(PMID:21828096)
BHF-UCL
PMID:21658587
PMID:21828096
PMID:24863063
NCBI chr 6:43,361,053...43,377,366
Ensembl chr 6:44,650,365...44,666,353
Term paths to the root
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Path 1
Term
Annotations
biological_process
19447
cellular process
19000
signal transduction
5489
cell surface receptor signaling pathway
2658
neuropilin signaling pathway
4
VEGF-activated neuropilin signaling pathway
2
VEGF-activated neuropilin signaling pathway involved in axon guidance
0
Path 2
Term
Annotations
biological_process
19447
biological regulation
11900
regulation of biological process
11518
signaling
5999
signal transduction
5489
cell surface receptor signaling pathway
2658
enzyme-linked receptor protein signaling pathway
952
cell surface receptor protein tyrosine kinase signaling pathway
621
vascular endothelial growth factor signaling pathway
87
VEGF-activated neuropilin signaling pathway
2
VEGF-activated neuropilin signaling pathway involved in axon guidance
0