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ONTOLOGY REPORT - ANNOTATIONS


Term:prolactin signaling pathway
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Accession:GO:0038161 term browser browse the term
Definition:The series of molecular signals initiated by the binding of the peptide hormone prolactin to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.
Synonyms:exact_synonym: PRL signaling pathway;   prolactin-mediated signaling pathway
 never_in_taxon: NCBITaxon:4751 ! Fungi



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prolactin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PRL prolactin involved_in IEA Ensembl GO_REF:0000107 NCBI chr35:20,673,830...20,683,824
Ensembl chr35:20,673,839...20,683,824
JBrowse link
G PRLR prolactin receptor involved_in IEA GOC GO_REF:0000108 NCBI chr 4:73,147,919...73,280,970
Ensembl chr 4:73,110,858...73,273,916
JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,550,003...51,558,861
Ensembl chr18:51,550,040...51,558,875
JBrowse link
positive regulation of prolactin signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CREBRF CREB3 regulatory factor acts_upstream_of_or_within ISO (PMID:23071095) MGI PMID:23071095 NCBI chr 4:39,308,429...39,366,031
Ensembl chr 4:39,313,512...39,365,953
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17075
    cellular process 16567
      signal transduction 6019
        hormone-mediated signaling pathway 212
          prolactin signaling pathway 4
            negative regulation of prolactin signaling pathway 0
            positive regulation of prolactin signaling pathway 1
            regulation of prolactin signaling pathway + 1
Path 2
Term Annotations click to browse term
  biological_process 17075
    biological regulation 11794
      regulation of biological process 11444
        regulation of cellular process 11109
          signal transduction 6019
            cell surface receptor signaling pathway 2633
              cytokine-mediated signaling pathway 474
                prolactin signaling pathway 4
                  negative regulation of prolactin signaling pathway 0
                  positive regulation of prolactin signaling pathway 1
                  regulation of prolactin signaling pathway + 1
paths to the root