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ONTOLOGY REPORT - ANNOTATIONS

Term:alphav-beta3 integrin-IGF-1-IGF1R complex
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Accession:GO:0035867 term browser browse the term
Definition:A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits.


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alphav-beta3 integrin-IGF-1-IGF1R complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igf1 insulin-like growth factor 1 part_of ISS
ISO
IEA		 GO_REF:0000024
(PMID:19578119)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:19578119 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor part_of IEA
ISO		 GO_REF:0000107
(PMID:19578119)		 Ensembl
RGD		 PMID:19578119 GO_REF:0000107 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Itgav integrin subunit alpha V part_of ISO (PMID:19578119) RGD PMID:19578119 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb3 integrin subunit beta 3 part_of ISO
IEA		 (PMID:19578119)
GO_REF:0000107		 RGD
Ensembl		 PMID:19578119 GO_REF:0000107 NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20827
    protein-containing complex 6555
      membrane protein complex 1410
        plasma membrane protein complex 670
          alphav-beta3 integrin-IGF-1-IGF1R complex 4
Path 2
Term Annotations click to browse term
  cellular_component 20827
    cellular anatomical structure 20627
      membrane 10365
        plasma membrane 6488
          plasma membrane protein complex 670
            alphav-beta3 integrin-IGF-1-IGF1R complex 4
paths to the root