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ONTOLOGY REPORT - ANNOTATIONS

Term:T-helper 1 cell activation
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Accession:GO:0035711 term browser browse the term
Definition:The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
Synonyms:exact_synonym: Th1 cell activation


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T-helper 1 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CEBPB CCAAT enhancer binding protein beta involved_in ISS UniProt GO_REF:0000024 NCBI chr20:50,190,583...50,192,690
Ensembl chr20:50,190,830...50,192,668 		JBrowse link
G HMGB1 high mobility group box 1 involved_in IDA (PMID:22473704) UniProt PMID:22473704 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G IL12A interleukin 12A acts_upstream_of_or_within ISO (PMID:22851706) MGI PMID:22851706 NCBI chr 3:159,988,835...159,996,019
Ensembl chr 3:159,988,835...159,996,019 		JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15284856) Ensembl
MGI		 PMID:15284856 GO_REF:0000107 NCBI chr11:68,039,025...68,053,762
Ensembl chr11:68,039,025...68,050,895 		JBrowse link
negative regulation of T-helper 1 cell activation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G XCL1 X-C motif chemokine ligand 1 involved_in IDA (PMID:10887101) BHF-UCL PMID:10887101 NCBI chr 1:168,576,605...168,582,069
Ensembl chr 1:168,576,605...168,582,069 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19613
    immune system process 3224
      leukocyte activation 1137
        lymphocyte activation 931
          T cell activation 666
            alpha-beta T cell activation 221
              CD4-positive, alpha-beta T cell activation 145
                T-helper 1 cell activation 5
                  negative regulation of T-helper 1 cell activation 1
                  positive regulation of T-helper 1 cell activation 0
                  regulation of T-helper 1 cell activation + 1
Path 2
Term Annotations click to browse term
  biological_process 19613
    cellular process 18246
      cell activation 1310
        leukocyte activation 1137
          lymphocyte activation 931
            T cell activation 666
              alpha-beta T cell activation 221
                CD4-positive, alpha-beta T cell activation 145
                  T-helper 1 cell activation 5
                    negative regulation of T-helper 1 cell activation 1
                    positive regulation of T-helper 1 cell activation 0
                    regulation of T-helper 1 cell activation + 1
paths to the root