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ONTOLOGY REPORT - ANNOTATIONS

Term:toll-like receptor 5 signaling pathway
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Accession:GO:0034146 term browser browse the term
Definition:The series of molecular signals initiated by a ligand binding to toll-like receptor 5.
Synonyms:exact_synonym: TLR5 signaling pathway;   toll-like receptor 5 signalling pathway


show annotations for term's descendants           Sort by:
toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MYD88 MYD88 innate immune signal transduction adaptor involved_in IEA Ensembl GO_REF:0000107 NCBI chr23:7,901,578...7,905,274
Ensembl chr23:7,901,250...7,904,534 		JBrowse link
G TIRAP TIR domain containing adaptor protein NOT|involved_in ISO (PMID:12447442) BHF-UCL PMID:12447442 NCBI chr 5:8,222,217...8,237,595
Ensembl chr 5:8,221,794...8,226,074 		JBrowse link
G TLR5 toll like receptor 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:23,700,323...23,705,628
Ensembl chr38:23,702,033...23,705,314 		JBrowse link
negative regulation of toll-like receptor 5 signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G TNFAIP3 TNF alpha induced protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:30,247,432...30,262,992
Ensembl chr 1:30,251,059...30,261,001 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17100
    immune system process 2468
      activation of immune response 521
        immune response-activating signaling pathway 461
          immune response-activating cell surface receptor signaling pathway 268
            innate immune response activating cell surface receptor signaling pathway 84
              cell surface pattern recognition receptor signaling pathway 79
                cell surface toll-like receptor signaling pathway 73
                  toll-like receptor 5 signaling pathway 4
                    negative regulation of toll-like receptor 5 signaling pathway 1
                    positive regulation of toll-like receptor 5 signaling pathway 0
                    regulation of toll-like receptor 5 signaling pathway + 1
Path 2
Term Annotations click to browse term
  biological_process 17100
    response to stimulus 9109
      response to external stimulus 2529
        response to external biotic stimulus 1664
          response to other organism 1661
            defense response to other organism 1128
              defense response to symbiont 1013
                innate immune response 850
                  regulation of innate immune response 457
                    positive regulation of innate immune response 376
                      activation of innate immune response 306
                        innate immune response-activating signaling pathway 286
                          innate immune response activating cell surface receptor signaling pathway 84
                            cell surface pattern recognition receptor signaling pathway 79
                              cell surface toll-like receptor signaling pathway 73
                                toll-like receptor 5 signaling pathway 4
                                  negative regulation of toll-like receptor 5 signaling pathway 1
                                  positive regulation of toll-like receptor 5 signaling pathway 0
                                  regulation of toll-like receptor 5 signaling pathway + 1
paths to the root