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ONTOLOGY REPORT - ANNOTATIONS

Term:melanosome organization
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Accession:GO:0032438 term browser browse the term
Definition:A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.
Synonyms:exact_synonym: melanosome organisation
 related_synonym: melanosome organization and biogenesis

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melanosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AP1M1 adaptor related protein complex 1 subunit mu 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:14,704,940...14,743,627
Ensembl chr 6:14,705,089...14,743,702 		JBrowse link
G AP3B1 adaptor related protein complex 3 subunit beta 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:11452004), (PMID:19841138)
(PMID:9931340)		 UniProt
MGI		 PMID:9931340 PMID:11452004 PMID:19841138 NCBI chr 4:72,225,658...72,524,971
Ensembl chr 4:72,225,599...72,524,933 		JBrowse link
G APOE apolipoprotein E involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:38,377,154...38,381,219
Ensembl chr 6:38,376,887...38,381,438 		JBrowse link
G ASIP agouti signaling protein acts_upstream_of_or_within ISO (PMID:9548375) MGI PMID:9548375 NCBI chr 2:38,479,328...38,568,756 JBrowse link
G ASIP agouti signaling protein involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr 2:38,480,960...38,562,339 JBrowse link
G BACE2 beta-secretase 2 involved_in ISO (PMID:23754390)
(MGI:5495053|PMID:23754390)		 UniProt PMID:23754390 MGI:5495053 NCBI chr 2:85,079,404...85,194,908
Ensembl chr 2:85,079,812...85,187,944 		JBrowse link
G BLOC1S3 biogenesis of lysosomal organelles complex 1 subunit 3 acts_upstream_of_or_within ISO (PMID:15265785) MGI PMID:15265785 NCBI chr 6:38,623,639...38,642,217
Ensembl chr 6:38,639,659...38,640,261 		JBrowse link
G BLOC1S4 biogenesis of lysosomal organelles complex 1 subunit 4 acts_upstream_of_or_within ISO (PMID:11110696) MGI PMID:11110696 NCBI chr27:42,836,231...42,837,514
Ensembl chr27:42,836,366...42,837,016 		JBrowse link
G GPR143 G protein-coupled receptor 143 involved_in ISO (PMID:19717472) UniProt PMID:19717472 NCBI chr  X:8,178,818...8,223,291
Ensembl chr  X:8,179,154...8,222,603 		JBrowse link
G KIF13A kinesin family member 13A involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:54,156,948...54,389,141
Ensembl chr17:54,156,969...54,390,502 		JBrowse link
G LYST lysosomal trafficking regulator acts_upstream_of_or_within ISO (PMID:4634048)
(PMID:16518687)		 MGI PMID:4634048 PMID:16518687 NCBI chr25:72,827,997...73,048,645
Ensembl chr25:72,828,006...72,991,970 		JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing involved_in ISO (MGI:6152906|PMID:29584722)
(PMID:29584722)		 UniProt PMID:29584722 MGI:6152906 NCBI chr10:94,051,096...94,144,968
Ensembl chr10:94,056,923...94,145,268 		JBrowse link
G PMEL premelanosome protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:51,892,131...51,905,073
Ensembl chr11:51,887,730...51,904,324 		JBrowse link
G SHROOM2 shroom family member 2 involved_in ISO (MGI:3710716|PMID:16987870) UniProt PMID:16987870 MGI:3710716 NCBI chr  X:8,242,714...8,405,051
Ensembl chr  X:8,345,056...8,405,552 		JBrowse link
G TYRP1 tyrosinase related protein 1 acts_upstream_of_or_within ISO (PMID:9548375) MGI PMID:9548375 NCBI chr12:66,841,867...66,861,730
Ensembl chr12:66,842,926...66,859,842 		JBrowse link
melanosome assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCB6 ATP binding cassette subfamily B member 6 (LAN blood group) involved_in IEA Ensembl GO_REF:0000107 NCBI chr10:105,113,729...105,122,948
Ensembl chr10:105,112,797...105,122,358 		JBrowse link
G HPS1 HPS1 biogenesis of lysosomal organelles complex 3 subunit 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:91,575,408...91,606,514
Ensembl chr 9:91,576,600...91,604,972 		JBrowse link
G HPS4 HPS4 biogenesis of lysosomal organelles complex 3 subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr19:9,356,868...9,387,847
Ensembl chr19:9,356,145...9,386,254 		JBrowse link
G RAB32 RAB32, member RAS oncogene family involved_in ISO (PMID:23084991)
(PMID:22511774)		 UniProt
ParkinsonsUK-UCL		 PMID:22511774 PMID:23084991 NCBI chr13:25,265,831...25,281,106 JBrowse link
G RAB38 RAB38, member RAS oncogene family involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:79,256,996...79,316,967
Ensembl chr 1:79,256,835...79,316,789 		JBrowse link
regulation of melanosome organization term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPR143 G protein-coupled receptor 143 involved_in ISO (MGI:3813974|PMID:18697795) UniProt PMID:18697795 MGI:3813974 NCBI chr  X:8,178,818...8,223,291
Ensembl chr  X:8,179,154...8,222,603 		JBrowse link
G ZEB2 zinc finger E-box binding homeobox 2 involved_in ISO (MGI:5574413|PMID:24769727) BHF-UCL PMID:24769727 MGI:5574413 NCBI chr10:29,732,934...29,864,157
Ensembl chr10:29,729,305...29,864,205 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16523
    cellular process 15422
      cellular pigmentation 44
        pigment granule organization 22
          melanosome organization 21
            melanosome assembly 5
            negative regulation of melanosome organization 0
            positive regulation of melanosome organization 0
            regulation of melanosome organization + 2
Path 2
Term Annotations click to browse term
  biological_process 16523
    cellular process 15422
      cellular component organization or biogenesis 6569
        cellular component organization 6357
          organelle organization 3542
            vesicle organization 344
              pigment granule organization 22
                melanosome organization 21
                  melanosome assembly 5
                  negative regulation of melanosome organization 0
                  positive regulation of melanosome organization 0
                  regulation of melanosome organization + 2
paths to the root