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ONTOLOGY REPORT - ANNOTATIONS

Term:MutLalpha complex
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Accession:GO:0032389 term browser browse the term
Definition:A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
Synonyms:exact_synonym: MLH1/PMS2 complex;   MutL-alpha complex
 broad_synonym: MMR complex


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MutLalpha complex term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 part_of IEA
IBA
ISO		 GO_REF:0000107
GO_REF:0000033
(PMID:16713580), (PMID:22164254)		 Ensembl
GO_Central
RGD		 PMID:16713580 PMID:22164254 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617 		JBrowse link
G Pms1 PMS1 homolog 1, mismatch repair system component part_of IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 9:48,229,403...48,340,237
Ensembl chr 9:48,253,410...48,340,237 		JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component part_of IBA
ISO		 GO_REF:0000033
(PMID:16713580)		 GO_Central
RGD		 PMID:16713580 GO_REF:0000033 NCBI chr12:10,676,818...10,701,161
Ensembl chr12:10,676,764...10,701,066 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20624
    protein-containing complex 6602
      mismatch repair complex 7
        MutLalpha complex 3
Path 2
Term Annotations click to browse term
  cellular_component 20624
    cellular anatomical entity 20386
      organelle 13799
        membrane-bounded organelle 12396
          intracellular membrane-bounded organelle 11845
            nucleus 7395
              nuclear protein-containing complex 1276
                MutLalpha complex 3
paths to the root