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ONTOLOGY REPORT - ANNOTATIONS


Term:MutLalpha complex
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Accession:GO:0032389 term browser browse the term
Definition:A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
Synonyms:exact_synonym: MLH1/PMS2 complex;   MutL-alpha complex
 broad_synonym: MMR complex


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MutLalpha complex term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mlh1 mutL homolog 1 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(MGI:MGI:3653556|PMID:16713580), (MGI:MGI:5315075|PMID:22164254)
Ensembl
RGD
PMID:16713580, PMID:22164254, PMID:21873635 GO_REF:0000107, MGI:MGI:3653556, MGI:MGI:5315075, RGD:13792537 NCBI chr 8:119,486,655...119,523,716
Ensembl chr 8:119,486,691...119,523,964
JBrowse link
G Pms2 PMS1 homolog 2, mismatch repair system component ISO
IBA
(MGI:MGI:3653556|PMID:16713580)
PMID:21873635
RGD PMID:16713580, PMID:21873635 MGI:MGI:3653556, RGD:13792537 NCBI chr12:12,714,394...12,738,654
Ensembl chr12:12,714,394...12,738,641
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 20610
    cellular anatomical entity 20359
      intracellular anatomical structure 14705
        mismatch repair complex 8
          MutLalpha complex 2
Path 2
Term Annotations click to browse term
  cellular_component 20610
    cellular anatomical entity 20359
      organelle 13271
        membrane-bounded organelle 11457
          intracellular membrane-bounded organelle 10714
            nucleus 7188
              MutLalpha complex 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.