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ONTOLOGY REPORT - ANNOTATIONS

Term:arachidonic acid metabolic process
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Accession:GO:0019369 term browser browse the term
Definition:The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
Synonyms:exact_synonym: arachidonic acid metabolism
 xref: Wikipedia:Arachidonic_acid

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arachidonic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox12b arachidonate 12-lipoxygenase, 12R type involved_in ISO PMID:23382512
(MGI:1313249|PMID:10100631), (MGI:6316908|PMID:11256953)
(MGI:3608217|PMID:16129665)
(PMID:15629692)		 UniProt PMID:10100631 PMID:11256953 PMID:15629692 PMID:16129665 PMID:23382512 MGI:1313249 MGI:3608217 MGI:6316908 RGD:8554649 NCBI chrNW_004955467:8,876,186...8,887,980
Ensembl chrNW_004955467:8,876,027...8,888,033 		JBrowse link
G Alox15 arachidonate 15-lipoxygenase involved_in ISO (PMID:8305485)
(MGI:1101294|PMID:8798642)
(MGI:66203|PMID:8188678)
PMID:23382512
(PMID:17052953), (PMID:1944593), (PMID:24282679), (PMID:8334154)		 RGD
UniProt		 PMID:1944593 PMID:8117750 PMID:8188678 PMID:8305485 PMID:8334154 More... MGI:1101294 MGI:66203 RGD:70288 RGD:8554649 NCBI chrNW_004955467:10,032,792...10,039,789 JBrowse link
G Alox15b arachidonate 15-lipoxygenase type B involved_in ISO (PMID:10542053), (PMID:10625675), (PMID:24282679), (PMID:24497644), (PMID:27145229), (PMID:9177185)
(MGI:1097306|PMID:9305900)
PMID:23382512		 UniProt PMID:9177185 PMID:9305900 PMID:10542053 PMID:10625675 PMID:23382512 More... MGI:1097306 RGD:8554649 NCBI chrNW_004955467:8,896,740...8,906,032
Ensembl chrNW_004955467:8,895,095...8,906,009 		JBrowse link
G Aloxe3 arachidonate lipoxygenase 3 involved_in ISO (PMID:12881489), (PMID:17045234)
(MGI:3694035|PMID:17045234)
PMID:23382512		 UniProt PMID:12881489 PMID:17045234 PMID:23382512 MGI:3694035 RGD:8554649 NCBI chrNW_004955467:8,844,805...8,869,230
Ensembl chrNW_004955467:8,844,805...8,869,964 		JBrowse link
G Dagla diacylglycerol lipase alpha involved_in
acts_upstream_of		 ISO (PMID:14610053)
(PMID:20147530)
(MGI:6423248|PMID:17584991)		 UniProt
MGI		 PMID:14610053 PMID:17584991 PMID:20147530 MGI:6423248 NCBI chrNW_004955511:5,952,134...5,997,280
Ensembl chrNW_004955511:5,952,087...5,974,172 		JBrowse link
G Daglb diacylglycerol lipase beta involved_in
acts_upstream_of		 ISO (PMID:14610053)
(PMID:20147530)
(MGI:6414691|PMID:23103940)		 UniProt
MGI		 PMID:14610053 PMID:20147530 PMID:23103940 MGI:6414691 NCBI chrNW_004955460:13,226,574...13,268,060
Ensembl chrNW_004955460:13,226,693...13,267,449 		JBrowse link
G Ephx1 epoxide hydrolase 1 involved_in ISO (PMID:24958911) UniProt PMID:24958911 NCBI chrNW_004955520:116,363...142,983
Ensembl chrNW_004955520:116,363...128,665 		JBrowse link
G Fads1 fatty acid desaturase 1 ISO RGD PMID:11414679 RGD:632758 NCBI chrNW_004955511:5,908,394...5,915,764
Ensembl chrNW_004955511:5,907,726...5,915,764 		JBrowse link
G Gpx1 glutathione peroxidase 1 involved_in ISO (PMID:11115402)
(MGI:893248|PMID:9195979)		 UniProt PMID:9195979 PMID:11115402 MGI:893248 NCBI chrNW_004955532:1,298,336...1,298,830 JBrowse link
G Gpx4 glutathione peroxidase 4 involved_in ISO (PMID:11115402) UniProt PMID:11115402 NCBI chrNW_004955495:6,767,969...6,772,256
Ensembl chrNW_004955495:6,767,975...6,772,178 		JBrowse link
G LOC102009223 cytochrome P450 1B1 involved_in ISO (PMID:15258110)
(MGI:5572883|PMID:15258110)		 UniProt PMID:15258110 MGI:5572883 NCBI chrNW_004955441:5,803,397...5,812,131
Ensembl chrNW_004955441:5,803,032...5,812,131 		JBrowse link
G Mapk3 mitogen-activated protein kinase 3 ISO RGD PMID:15027896 RGD:1626220 NCBI chrNW_004955493:6,870,699...6,876,836
Ensembl chrNW_004955493:6,869,668...6,879,152 		JBrowse link
G Mgll monoglyceride lipase involved_in ISO (MGI:4836780|PMID:20729846) UniProt PMID:20729846 MGI:4836780 NCBI chrNW_004955429:15,760,159...15,960,774
Ensembl chrNW_004955429:15,759,540...15,960,835 		JBrowse link
G Pla2g2f phospholipase A2 group IIF involved_in ISO (MGI:6467677|PMID:11877435) UniProt PMID:11877435 MGI:6467677 NCBI chrNW_004955452:755,738...765,304
Ensembl chrNW_004955452:755,478...763,571 		JBrowse link
G Pla2g4a phospholipase A2 group IVA involved_in ISO (PMID:7794891) RGD
UniProt		 PMID:7794891 PMID:16603549 RGD:1642459 NCBI chrNW_004955406:25,257,361...25,392,079
Ensembl chrNW_004955406:25,257,355...25,394,206 		JBrowse link
G Pnpla8 patatin like phospholipase domain containing 8 involved_in ISO (PMID:10833412), (PMID:15695510), (PMID:28442572) UniProt PMID:10833412 PMID:15695510 PMID:28442572 NCBI chrNW_004955410:12,715,072...12,753,433
Ensembl chrNW_004955410:12,711,082...12,753,433 		JBrowse link
cyclooxygenase pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bdkrb1 bradykinin receptor B1 involved_in ISO (PMID:23846981) AgBase PMID:23846981 NCBI chrNW_004955438:16,500,219...16,505,394
Ensembl chrNW_004955438:16,500,633...16,501,691 		JBrowse link
G LOC102030058 protein SCO1 homolog, mitochondrial acts_upstream_of_or_within ISO (PMID:28973536) MGI PMID:28973536 NCBI chrNW_004955467:6,519,873...6,535,321
Ensembl chrNW_004955467:6,519,873...6,537,753 		JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 involved_in ISO (PMID:1380156) BHF-UCL PMID:1380156 NCBI chrNW_004955419:5,678,750...5,699,305
Ensembl chrNW_004955419:5,678,694...5,699,305 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 involved_in
acts_upstream_of_or_within		 ISO (PMID:1380156), (PMID:7592599), (PMID:7947975)
(PMID:1419907)
(MGI:5315361|PMID:12925531)		 UniProt
MGI		 PMID:1380156 PMID:1419907 PMID:7592599 PMID:7947975 PMID:12925531 MGI:5315361 NCBI chrNW_004955406:25,077,988...25,086,259
Ensembl chrNW_004955406:25,079,945...25,086,171 		JBrowse link
G Sphk1 sphingosine kinase 1 ISO RGD PMID:18723875 RGD:2311353 NCBI chrNW_004955506:5,902,079...5,906,639
Ensembl chrNW_004955506:5,902,345...5,904,988 		JBrowse link
omega-hydroxylase P450 pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl hydrocarbon receptor ISO RGD PMID:19889059 RGD:401794453 NCBI chrNW_004955410:20,428,531...20,459,482
Ensembl chrNW_004955410:20,428,546...20,456,836 		JBrowse link
G LOC102028874 cytochrome P450 2U1 involved_in ISO (PMID:24563460) UniProt PMID:24563460 NCBI chrNW_004955496:1,873,031...1,887,840
Ensembl chrNW_004955496:1,875,401...1,882,542 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12362
    metabolic process 7489
      organic substance metabolic process 7172
        olefinic compound metabolic process 85
          arachidonic acid metabolic process 23
            cyclooxygenase pathway 5
            epoxygenase P450 pathway 0
            omega-hydroxylase P450 pathway 2
Path 2
Term Annotations click to browse term
  biological_process 12362
    metabolic process 7489
      cellular metabolic process 6296
        organic acid metabolic process 662
          oxoacid metabolic process 658
            carboxylic acid metabolic process 650
              monocarboxylic acid metabolic process 460
                fatty acid metabolic process 284
                  unsaturated fatty acid metabolic process 61
                    arachidonic acid metabolic process 23
                      cyclooxygenase pathway 5
                      epoxygenase P450 pathway 0
                      omega-hydroxylase P450 pathway 2
paths to the root