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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of vitamin D biosynthetic process
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Accession:GO:0010957 term browser browse the term
Definition:Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).



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negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SNAI1 snail family transcriptional repressor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:51,546,446...51,552,498
Ensembl chr17:51,546,477...51,552,499
JBrowse link
G SNAI2 snail family transcriptional repressor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:79,264,880...79,268,475
Ensembl chr 4:79,264,880...79,268,475
JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 involved_in ISO (PMID:16549446) BHF-UCL PMID:16549446 NCBI chr 5:23,053,129...23,058,865
Ensembl chr 5:23,053,892...23,058,470
JBrowse link
G GFI1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) BHF-UCL PMID:15947108 NCBI chr 4:124,619,887...124,629,638
Ensembl chr 4:124,621,261...124,629,638
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 involved_in ISO (PMID:15243130) BHF-UCL PMID:15243130 NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,638...118,506,691
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17677
    cellular process 17216
      negative regulation of cellular process 5356
        negative regulation of metabolic process 3073
          negative regulation of small molecule metabolic process 128
            negative regulation of vitamin metabolic process 7
              negative regulation of vitamin D biosynthetic process 5
                negative regulation of calcidiol 1-monooxygenase activity 3
Path 2
Term Annotations click to browse term
  biological_process 17677
    biological regulation 12827
      regulation of biological process 12454
        regulation of cellular process 12123
          regulation of metabolic process 6342
            regulation of primary metabolic process 5264
              regulation of lipid metabolic process 380
                regulation of steroid metabolic process 121
                  negative regulation of steroid metabolic process 31
                    negative regulation of steroid biosynthetic process 29
                      negative regulation of vitamin D biosynthetic process 5
                        negative regulation of calcidiol 1-monooxygenase activity 3
paths to the root