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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of small molecule metabolic process
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Accession:GO:0062014 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.
Synonyms:exact_synonym: negative regulation of small molecule metabolism



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negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:19584291)
Ensembl
RGD
PMID:19584291 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP
(PMID:19342457)
GO_REF:0000107
RGD
Ensembl
PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc27a4 solute carrier family 27 member 4 involved_in ISO (MGI:5471874|PMID:23407971) RGD PMID:23407971 MGI:5471874 NCBI chr 3:13,075,022...13,087,943
Ensembl chr 3:13,075,022...13,087,943
JBrowse link
negative regulation of arginine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IMP RGD PMID:21325440 RGD:9685453 NCBI chr 1:239,425,515...239,552,323
Ensembl chr 1:239,425,430...239,552,317
JBrowse link
G Flcn folliculin involved_in ISS
ISO
GO_REF:0000024
(MGI:5463828|PMID:23150719)
UniProt
RGD
PMID:23150719 GO_REF:0000024 MGI:5463828 NCBI chr10:44,588,621...44,607,808
Ensembl chr10:44,588,624...44,607,769
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO (PMID:24289924) RGD PMID:24289924 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) RGD PMID:20165904 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044
JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within
ISO (PMID:12815072)
MGI:1928271 (MGI:5501367|PMID:23747249)
RGD PMID:12815072 PMID:23747249 MGI:5501367 NCBI chr 1:200,056,656...200,059,944
Ensembl chr 1:200,056,644...200,060,287
JBrowse link
G Malrd1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within ISO MGI:1096383|MGI:2154956 (MGI:5501367|PMID:23747249) RGD PMID:23747249 MGI:5501367 NCBI chr17:78,418,819...79,131,016
Ensembl chr17:78,418,819...79,131,016
JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:16488887) RGD PMID:16488887 NCBI chr13:101,669,184...101,719,804
Ensembl chr13:101,669,184...101,711,183
JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO (PMID:16549446) RGD PMID:16549446 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) RGD PMID:15947108 NCBI chr14:2,040,576...2,056,874
Ensembl chr14:2,042,434...2,051,814
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:15243130)
Ensembl
RGD
PMID:15243130 GO_REF:0000107 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
negative regulation of cellular glucuronidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 involved_in ISO (PMID:18004212) RGD PMID:18004212 NCBI chr 9:88,801,344...88,808,465 JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 involved_in ISO (PMID:20610558) RGD PMID:20610558 NCBI chr 9:88,727,094...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 involved_in ISO (PMID:18004212), (PMID:20610558) RGD PMID:18004212 PMID:20610558 NCBI chr 9:88,696,981...88,808,465 JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
ISO
IEA
(PMID:1917954)
GO_REF:0000107
RGD
Ensembl
PMID:1917954 PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (MGI:5490819|PMID:17202134) RGD PMID:17202134 MGI:5490819 NCBI chr17:61,331,669...61,334,285
Ensembl chr17:61,331,669...61,334,285
JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:15473258)
UniProt
RGD
PMID:15473258 GO_REF:0000024 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA
(PMID:19584291)
GO_REF:0000107
RGD
Ensembl
PMID:19584291 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:166,237,969...166,281,271
Ensembl chr 1:166,238,238...166,280,590
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP
(PMID:19342457)
GO_REF:0000107
RGD
Ensembl
PMID:19342457 PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:30,859,109...30,879,828
Ensembl chr14:30,862,553...30,894,354
JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (MGI:3530688|PMID:15677334), (MGI:3629477|PMID:12920182) RGD PMID:12920182 PMID:15677334 MGI:3530688 MGI:3629477 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:16814735) RGD PMID:16814735 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19724020 RGD:2314644 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein IDA RGD PMID:11485163 RGD:2316274 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A acts_upstream_of_or_within ISO (MGI:5474727|PMID:23209793) RGD PMID:23209793 MGI:5474727 NCBI chr 5:135,225,801...135,240,744
Ensembl chr 5:135,225,816...135,240,690
JBrowse link
G Pink1 PTEN induced kinase 1 HMP RGD PMID:25421206 RGD:11560775 NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
JBrowse link
G Plin5 perilipin 5 involved_in ISS
ISO
GO_REF:0000024
(MGI:5440401|PMID:22532565), (MGI:5559662|PMID:22675471), (MGI:5559666|PMID:21885430)
UniProt
RGD
PMID:21885430 PMID:22532565 PMID:22675471 GO_REF:0000024 MGI:5440401 MGI:5559662 MGI:5559666 NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120
JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etfbkmt electron transfer flavoprotein subunit beta lysine methyltransferase involved_in ISO
ISS
(PMID:25416781)
(MGI:5700285|PMID:25023281)
GO_REF:0000024
RGD
UniProt
PMID:25023281 PMID:25416781 GO_REF:0000024 MGI:5700285 NCBI chr 4:182,140,492...182,204,635
Ensembl chr 4:182,140,559...182,150,305
JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:3526480 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO
GO_REF:0000107
(MGI:3526480|PMID:15639194)
Ensembl
RGD
PMID:15639194 GO_REF:0000107 MGI:3526480 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) RGD PMID:15576844 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IEA
(PMID:11060345), (PMID:18635818)
GO_REF:0000107
RGD
Ensembl
PMID:11060345 PMID:18635818 GO_REF:0000107 NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA
ISS
IBA
(PMID:16326698)
GO_REF:0000107
GO_REF:0000024
PMID:21873635
RGD
Ensembl
UniProt
PMID:16326698 PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IMP PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chr 1:81,043,595...81,060,050
Ensembl chr 1:81,043,595...81,059,992
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:65,017,654...65,034,184
Ensembl chr16:65,018,532...65,033,671
JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO MGI:1920249 (MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:3603108 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO MGI:1916289 (MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:3603108 NCBI chr13:32,472,390...32,500,139
Ensembl chr13:32,473,742...32,494,923
JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISO (MGI:3630230|PMID:16794074) RGD PMID:16794074 MGI:3630230 NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497
JBrowse link
G Wdtc1 WD and tetratricopeptide repeats 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3770497|PMID:17767906)
RGD PMID:17767906 PMID:21873635 MGI:3770497, RGD:13792537 NCBI chr 5:145,491,461...145,559,631
Ensembl chr 5:145,491,466...145,540,408
JBrowse link
negative regulation of fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 involved_in ISO (PMID:1184755) RGD PMID:1184755 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO
IEA
(PMID:19955185)
GO_REF:0000107
RGD
Ensembl
PMID:19955185 GO_REF:0000107 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Slc22a13l1 solute carrier family 22 member 13-like 1 involved_in ISO (PMID:24769897)
(MGI:6212098|PMID:24769897)
RGD PMID:24769897 MGI:6212098 NCBI chr 8:118,958,209...118,972,614
Ensembl chr 8:118,961,000...118,966,046
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 involved_in ISO (PMID:20610558) RGD PMID:20610558 NCBI chr 9:88,727,094...88,808,465 JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 involved_in ISO (PMID:20610558) RGD PMID:20610558 NCBI chr 9:88,696,981...88,808,465 JBrowse link
negative regulation of fatty acid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (MGI:1932690|PMID:11283375), (MGI:3804564|PMID:18487439) RGD PMID:11283375 PMID:18487439 MGI:1932690 MGI:3804564 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:3526480 NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO
GO_REF:0000107
(MGI:3526480|PMID:15639194)
Ensembl
RGD
PMID:15639194 GO_REF:0000107 MGI:3526480 NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:4420367|PMID:19661063) RGD PMID:19661063 MGI:4420367 NCBI chr 7:20,135,248...20,184,757
Ensembl chr 7:20,135,375...20,184,754
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
JBrowse link
G Mir199a2 microRNA 199a-2 acts_upstream_of_or_within ISO (MGI:5528778|PMID:24011070) RGD PMID:24011070 MGI:5528778 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063
JBrowse link
G Sirt4 sirtuin 4 involved_in ISO (PMID:24043310)
(MGI:5501374|PMID:23746352), (MGI:5547879|PMID:24043310)
RGD PMID:23746352 PMID:24043310 MGI:5501374 MGI:5547879 NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
GO_REF:0000024
(MGI:6414737|PMID:32103177)
UniProt
RGD
PMID:32103177 GO_REF:0000024 MGI:6414737 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994
JBrowse link
negative regulation of gluconeogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:3055866|PMID:11479628)
UniProt
RGD
PMID:11479628 GO_REF:0000024 MGI:3055866 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G C1qtnf12 C1q and TNF related 12 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5317500|PMID:22275362)
RGD PMID:22275362 PMID:21873635 MGI:5317500, RGD:13792537 NCBI chr 5:166,551,628...166,556,003
Ensembl chr 5:166,551,628...166,556,003
JBrowse link
G C1qtnf3 C1q and TNF related 3 involved_in
acts_upstream_of_or_within
ISO (PMID:20952387)
(MGI:4868567|PMID:20952387)
RGD PMID:20952387 MGI:4868567 NCBI chr 2:59,917,099...59,939,519
Ensembl chr 2:59,917,188...59,939,433
JBrowse link
G Clk2 CDC-like kinase 2 involved_in ISO (MGI:4429735|PMID:20074525) RGD PMID:20074525 MGI:4429735 NCBI chr 2:174,570,614...174,582,645 JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5914352|PMID:28790135), (MGI:6208175|PMID:29937374)
UniProt
RGD
PMID:28790135 PMID:29937374 GO_REF:0000024 MGI:5914352 MGI:6208175 NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091
JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:30193097) RGD PMID:30193097 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
JBrowse link
G Erfe erythroferrone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:91,956,971...91,964,846
Ensembl chr 9:91,956,977...91,964,846
JBrowse link
G Fam3a FAM3 metabolism regulating signaling molecule A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:152,166,716...152,175,327
Ensembl chr  X:152,165,535...152,175,362
JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:50,839,929...50,887,276
Ensembl chr 4:50,838,818...50,888,078
JBrowse link
G Gck glucokinase involved_in ISO
IEA
ISS
(PMID:8878425)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:8878425 GO_REF:0000024 GO_REF:0000107 NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
JBrowse link
G Il6 interleukin 6 IDA In liver RGD PMID:16308834 RGD:2306940 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:8069456) RGD PMID:8069456 NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
JBrowse link
G Lepr leptin receptor acts_upstream_of_or_within ISO MGI:1856009 (MGI:5529403|PMID:24051374) RGD PMID:24051374 MGI:5529403 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G LOC259246 alpha-2u globulin PGCL1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024
G Mst1 macrophage stimulating 1 involved_in ISO (PMID:19720831) RGD PMID:19720831 NCBI chr 8:108,767,886...108,773,425
Ensembl chr 8:108,768,839...108,773,416
JBrowse link
G Obp2a odorant binding protein 2A acts_upstream_of_or_within ISO MGI:2137691 (MGI:4946468|PMID:21135134) RGD PMID:21135134 MGI:4946468 NCBI chr 3:8,505,990...8,509,269
Ensembl chr 3:8,505,990...8,509,269
JBrowse link
G Pgp phosphoglycolate phosphatase involved_in IMP
ISO
PMID:26755581
(PMID:26755581)
RGD PMID:26755581 PMID:26755581 RGD:10679995 NCBI chr10:13,495,232...13,497,858
Ensembl chr10:13,494,291...13,497,858
JBrowse link
G Serpina12 serpin family A member 12 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5563627|PMID:22837305)
Ensembl
RGD
PMID:22837305 GO_REF:0000107 MGI:5563627 NCBI chr 6:122,952,552...122,967,271
Ensembl chr 6:122,952,552...122,967,271
JBrowse link
G Sik1 salt-inducible kinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3606826|PMID:16148943)
UniProt
RGD
PMID:16148943 GO_REF:0000024 MGI:3606826 NCBI chr20:9,949,407...9,959,036
Ensembl chr20:9,947,396...9,958,991
JBrowse link
G Soga1 suppressor of glucose, autophagy associated 1 involved_in ISO (MGI:4837302|PMID:20813965) RGD PMID:20813965 MGI:4837302 NCBI chr 3:145,669,102...145,741,578
Ensembl chr 3:145,675,443...145,740,871
JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:56,098,080...56,192,188
Ensembl chr 3:56,097,269...56,192,100
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
negative regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atcay ATCAY kinesin light chain interacting caytaxin involved_in ISO
ISS
(PMID:16899818)
GO_REF:0000024
RGD
UniProt
PMID:16899818 GO_REF:0000024 NCBI chr 7:8,487,763...8,511,527
Ensembl chr 7:8,487,763...8,512,663
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) RGD PMID:17828264 MGI:3759354 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012
JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:23840896) RGD PMID:23840896 NCBI chr19:50,679,897...50,750,028
Ensembl chr19:50,680,729...50,749,610
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4440406|PMID:20176937)
Ensembl
RGD
PMID:20176937 GO_REF:0000107 MGI:4440406 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19881551), (PMID:25043030)
UniProt
Ensembl
RGD
PMID:19881551 PMID:25043030 GO_REF:0000024 GO_REF:0000107 NCBI chr17:2,207,271...2,230,076
Ensembl chr17:2,208,031...2,230,071
JBrowse link
G Git1 GIT ArfGAP 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6478067|PMID:32460388)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:32460388 GO_REF:0000024 GO_REF:0000107 MGI:6478067 NCBI chr10:62,342,082...62,356,379
Ensembl chr10:62,342,299...62,356,373
JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO (MGI:4365327|PMID:19109424) RGD PMID:19109424 MGI:4365327 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO MGI:3773690 (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:5662300 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Myog myogenin IDA RGD PMID:10225962 RGD:9686132 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19955185)
Ensembl
RGD
PMID:19955185 GO_REF:0000107 NCBI chr10:46,999,536...47,142,294
Ensembl chr10:46,999,536...47,141,032
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
ISS
(PMID:30451898)
GO_REF:0000024
RGD
UniProt
PMID:30451898 GO_REF:0000024 NCBI chr 1:181,213,292...181,215,327 JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19955185) RGD PMID:19955185 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:22343369 RGD:7242186 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (MGI:4881401|PMID:20141841), (MGI:5619441|PMID:23217706) RGD PMID:20141841 PMID:23217706 MGI:4881401 MGI:5619441 NCBI chr 7:8,082,312...8,087,776
Ensembl chr 7:8,082,364...8,098,914
JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO (MGI:5441121|PMID:22891351) RGD PMID:22891351 MGI:5441121 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4867601|PMID:20935145)
RGD PMID:20935145 PMID:21873635 MGI:4867601, RGD:13792537 NCBI chr 4:159,927,138...159,946,094
Ensembl chr 4:159,927,139...159,946,029
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3820439|PMID:18698006)
Ensembl
RGD
PMID:18698006 GO_REF:0000107 MGI:3820439 NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:141,455,616...141,466,252
Ensembl chr 5:141,455,613...141,463,841
JBrowse link
G Pdzd3 PDZ domain containing 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:44,584,390...44,588,838
Ensembl chr 8:44,584,390...44,588,860
JBrowse link
G Rd3 RD3 regulator of GUCY2D involved_in ISO (PMID:21928830), (PMID:30559291)
(MGI:5810226|PMID:27471269)
RGD PMID:21928830 PMID:27471269 PMID:30559291 MGI:5810226 NCBI chr13:103,551,823...103,562,925
Ensembl chr13:103,552,857...103,562,622
JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin involved_in ISO (PMID:7559487), (PMID:7782310) RGD PMID:7559487 PMID:7782310 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:7535379 RGD:7777104 NCBI chr 1:228,409,883...229,638,794 JBrowse link
negative regulation of nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cda cytidine deaminase involved_in ISO (PMID:9596658) RGD PMID:9596658 NCBI chr 5:150,556,615...150,583,231
Ensembl chr 5:150,556,615...150,583,231
JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:3863495) RGD PMID:3863495 NCBI chr15:75,850,389...76,019,711
Ensembl chr15:75,850,624...76,019,712
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5306564|PMID:20042607) RGD PMID:20042607 MGI:5306564 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000104
(PMID:12140278)
UniProt
RGD
PMID:12140278 GO_REF:0000024 GO_REF:0000104 NCBI chr13:39,200,486...39,244,337
Ensembl chr13:39,200,314...39,245,209
JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:21851338) RGD PMID:21851338 NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873
JBrowse link
G Prmt3 protein arginine methyltransferase 3 involved_in ISO
ISS
IEA
(PMID:33495566)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:33495566 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:99,492,712...99,581,774
Ensembl chr 1:99,492,724...99,579,435
JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 involved_in ISO (MGI:3839065|PMID:18818293) RGD PMID:18818293 MGI:3839065 NCBI chr 1:95,694,010...95,699,259
Ensembl chr 1:95,694,010...95,699,259
JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA
(PMID:12949260)
(MGI:2675528|PMID:12949260)
GO_REF:0000107
RGD
Ensembl
PMID:12949260 GO_REF:0000107 MGI:2675528 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859
JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:19502595) RGD PMID:19502595 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) RGD PMID:18485278 PMID:19502595 NCBI chr11:86,183,800...86,186,109
Ensembl chr11:86,181,909...86,186,200
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19497
    metabolic process 11824
      negative regulation of metabolic process 3218
        negative regulation of small molecule metabolic process 104
          negative regulation of (R)-mevalonic acid biosynthetic process 0
          negative regulation of UDP-N-acetylglucosamine biosynthetic process 0
          negative regulation of UDP-glucose catabolic process 0
          negative regulation of acetate catabolic process 0
          negative regulation of aflatoxin biosynthetic process 0
          negative regulation of alcohol biosynthetic process + 14
          negative regulation of aldosterone metabolic process + 4
          negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity 1
          negative regulation of androst-4-ene-3,17-dione biosynthetic process 0
          negative regulation of asperthecin biosynthetic process 0
          negative regulation of bile acid metabolic process + 3
          negative regulation of cellular alcohol catabolic process 0
          negative regulation of cellular amino acid metabolic process + 2
          negative regulation of cellular glucuronidation 3
          negative regulation of cholesterol metabolic process + 5
          negative regulation of cordyol C biosynthetic process 0
          negative regulation of diorcinol biosynthetic process 0
          negative regulation of ecdysteroid metabolic process + 0
          negative regulation of emodin biosynthetic process 0
          negative regulation of endocrocin biosynthetic process 0
          negative regulation of fatty acid metabolic process + 33
          negative regulation of ferulate catabolic process 0
          negative regulation of fumagillin biosynthetic process 0
          negative regulation of fumonisin biosynthetic process 0
          negative regulation of gerfelin biosynthetic process 0
          negative regulation of gibberellin biosynthetic process 0
          negative regulation of gluconeogenesis 20
          negative regulation of glucose catabolic process to lactate via pyruvate 3
          negative regulation of glyoxylate cycle 0
          negative regulation of helvolic acid biosynthetic process 0
          negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway 0
          negative regulation of methane biosynthetic process from formic acid 0
          negative regulation of methyl-branched fatty acid biosynthetic process 0
          negative regulation of monodictyphenone biosynthetic process 0
          negative regulation of naphtho-gamma-pyrone biosynthetic process 0
          negative regulation of nucleoside metabolic process 0
          negative regulation of nucleotide metabolic process + 25
          negative regulation of o-orsellinic acid biosynthetic process 0
          negative regulation of penicillin metabolic process + 0
          negative regulation of progesterone biosynthetic process + 0
          negative regulation of purine nucleobase metabolic process 0
          negative regulation of pyrimidine nucleobase metabolic process 0
          negative regulation of quinolinate biosynthetic process 1
          negative regulation of sarcinapterin metabolic process + 0
          negative regulation of sulfur amino acid metabolic process + 0
          negative regulation of tatiopterin metabolic process + 0
          negative regulation of tensidol A biosynthetic process 0
          negative regulation of tensidol B biosynthetic process 0
          negative regulation of terrequinone A biosynthetic process 0
          negative regulation of testosterone biosynthetic process 2
          negative regulation of ubiquinone biosynthetic process 0
          negative regulation of urea catabolic process 0
          negative regulation of violaceol I biosynthetic process 0
          negative regulation of violaceol II biosynthetic process 0
          negative regulation of vitamin metabolic process + 7
          negative regulation of xanthone-containing compound biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19497
    biological regulation 13606
      regulation of biological process 12866
        regulation of metabolic process 6832
          regulation of small molecule metabolic process 376
            negative regulation of small molecule metabolic process 104
              negative regulation of (R)-mevalonic acid biosynthetic process 0
              negative regulation of UDP-N-acetylglucosamine biosynthetic process 0
              negative regulation of UDP-glucose catabolic process 0
              negative regulation of acetate catabolic process 0
              negative regulation of aflatoxin biosynthetic process 0
              negative regulation of alcohol biosynthetic process + 14
              negative regulation of aldosterone metabolic process + 4
              negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity 1
              negative regulation of androst-4-ene-3,17-dione biosynthetic process 0
              negative regulation of asperthecin biosynthetic process 0
              negative regulation of bile acid metabolic process + 3
              negative regulation of cellular alcohol catabolic process 0
              negative regulation of cellular amino acid metabolic process + 2
              negative regulation of cellular glucuronidation 3
              negative regulation of cholesterol metabolic process + 5
              negative regulation of cordyol C biosynthetic process 0
              negative regulation of diorcinol biosynthetic process 0
              negative regulation of ecdysteroid metabolic process + 0
              negative regulation of emodin biosynthetic process 0
              negative regulation of endocrocin biosynthetic process 0
              negative regulation of fatty acid metabolic process + 33
              negative regulation of ferulate catabolic process 0
              negative regulation of fumagillin biosynthetic process 0
              negative regulation of fumonisin biosynthetic process 0
              negative regulation of gerfelin biosynthetic process 0
              negative regulation of gibberellin biosynthetic process 0
              negative regulation of gluconeogenesis 20
              negative regulation of glucose catabolic process to lactate via pyruvate 3
              negative regulation of glyoxylate cycle 0
              negative regulation of helvolic acid biosynthetic process 0
              negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway 0
              negative regulation of methane biosynthetic process from formic acid 0
              negative regulation of methyl-branched fatty acid biosynthetic process 0
              negative regulation of monodictyphenone biosynthetic process 0
              negative regulation of naphtho-gamma-pyrone biosynthetic process 0
              negative regulation of nucleoside metabolic process 0
              negative regulation of nucleotide metabolic process + 25
              negative regulation of o-orsellinic acid biosynthetic process 0
              negative regulation of penicillin metabolic process + 0
              negative regulation of progesterone biosynthetic process + 0
              negative regulation of purine nucleobase metabolic process 0
              negative regulation of pyrimidine nucleobase metabolic process 0
              negative regulation of quinolinate biosynthetic process 1
              negative regulation of sarcinapterin metabolic process + 0
              negative regulation of sulfur amino acid metabolic process + 0
              negative regulation of tatiopterin metabolic process + 0
              negative regulation of tensidol A biosynthetic process 0
              negative regulation of tensidol B biosynthetic process 0
              negative regulation of terrequinone A biosynthetic process 0
              negative regulation of testosterone biosynthetic process 2
              negative regulation of ubiquinone biosynthetic process 0
              negative regulation of urea catabolic process 0
              negative regulation of violaceol I biosynthetic process 0
              negative regulation of violaceol II biosynthetic process 0
              negative regulation of vitamin metabolic process + 7
              negative regulation of xanthone-containing compound biosynthetic process + 0
paths to the root