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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of small molecule metabolic process
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Accession:GO:0062014 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process.
Synonyms:exact_synonym: negative regulation of small molecule metabolism


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negative regulation of aldosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:19584291)
Ensembl
RGD
PMID:19584291 GO_REF:0000107 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:176,940,424...176,983,076
Ensembl chr 1:176,940,693...176,983,045
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP
(PMID:19342457)
GO_REF:0000107
RGD
Ensembl
PMID:19342457, PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc27a4 solute carrier family 27 member 4 involved_in ISO (MGI:5471874|PMID:23407971) RGD PMID:23407971 MGI:5471874 NCBI chr 3:8,363,937...8,376,858
Ensembl chr 3:8,363,937...8,376,858
JBrowse link
negative regulation of arginine catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
negative regulation of ATP biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 IMP RGD PMID:21325440 RGD:9685453 NCBI chr 1:259,692,020...259,818,922
Ensembl chr 1:259,739,955...259,819,494
JBrowse link
G Flcn folliculin involved_in ISS
ISO
GO_REF:0000024
(MGI:5463828|PMID:23150719)
UniProt
RGD
PMID:23150719 GO_REF:0000024 MGI:5463828 NCBI chr10:46,153,185...46,172,331
Ensembl chr10:46,153,188...46,172,309
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in ISO (PMID:24289924) RGD PMID:24289924 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 involved_in ISO (PMID:20165904) RGD PMID:20165904 NCBI chr 9:91,667,748...91,683,468
Ensembl chr 9:91,665,986...91,882,927
JBrowse link
negative regulation of bile acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf19 fibroblast growth factor 19 involved_in
acts_upstream_of_or_within
ISO (PMID:12815072)
MGI:1928271 (MGI:5501367|PMID:23747249)
RGD PMID:12815072 PMID:23747249 MGI:5501367 NCBI chr 1:218,058,405...218,061,693
Ensembl chr 1:218,058,405...218,061,693
JBrowse link
G Malrd1 MAM and LDL receptor class A domain containing 1 acts_upstream_of_or_within ISO MGI:1096383|MGI:2154956 (MGI:5501367|PMID:23747249) RGD PMID:23747249 MGI:5501367 NCBI chr17:82,430,836...83,156,696
Ensembl chr17:82,430,836...82,953,864
JBrowse link
G Prox1 prospero homeobox 1 involved_in ISO (PMID:16488887) RGD PMID:16488887 NCBI chr13:108,382,536...108,444,107
Ensembl chr13:108,382,399...108,443,294
JBrowse link
negative regulation of calcidiol 1-monooxygenase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 involved_in ISO (PMID:16549446) RGD PMID:16549446 NCBI chr 7:70,333,150...70,340,006
Ensembl chr 7:70,335,061...70,340,005
JBrowse link
G Gfi1 growth factor independent 1 transcriptional repressor involved_in ISO (PMID:15947108) RGD PMID:15947108 NCBI chr14:3,058,035...3,073,332
Ensembl chr14:3,058,993...3,068,371
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:15243130)
Ensembl
RGD
PMID:15243130 GO_REF:0000107 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
negative regulation of cellular glucuronidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a1 UDP glucuronosyltransferase family 1 member A1 involved_in ISO (PMID:18004212) RGD PMID:18004212 NCBI chr 9:95,295,701...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 involved_in ISO (PMID:20610558) RGD PMID:20610558 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 involved_in ISO (PMID:18004212), (PMID:20610558) RGD PMID:18004212 PMID:20610558 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
negative regulation of cholesterol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apoe apolipoprotein E involved_in IDA
ISO
IEA
(PMID:1917954)
GO_REF:0000107
RGD
Ensembl
PMID:1917954, PMID:9225228 GO_REF:0000107, RGD:10059686 NCBI chr 1:80,612,894...80,616,820
Ensembl chr 1:80,612,895...80,617,057
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:263,810,439...263,845,762
Ensembl chr 1:263,810,439...263,845,762
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:69,179,005...69,195,452
Ensembl chr16:69,179,588...69,195,097
JBrowse link
G Idi2 isopentenyl-diphosphate delta isomerase 2 acts_upstream_of_or_within ISO (MGI:5490819|PMID:17202134) RGD PMID:17202134 MGI:5490819 NCBI chr17:63,107,152...63,107,469 JBrowse link
G Sod1 superoxide dismutase 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:15473258)
UniProt
RGD
PMID:15473258 GO_REF:0000024 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
negative regulation of citrulline biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:19278978) RGD PMID:19278978 NCBI chr13:50,091,644...50,153,808
Ensembl chr13:50,091,430...50,153,823
JBrowse link
negative regulation of cortisol biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in ISO
IEA
(PMID:19584291)
GO_REF:0000107
RGD
Ensembl
PMID:19584291 GO_REF:0000107 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:82,669,466...82,950,273
Ensembl chr 8:82,878,941...82,950,273
JBrowse link
G Dkk3 dickkopf WNT signaling pathway inhibitor 3 involved_in ISO (PMID:16981135) RGD PMID:16981135 NCBI chr 1:176,940,424...176,983,076
Ensembl chr 1:176,940,693...176,983,045
JBrowse link
G Rest RE1-silencing transcription factor involved_in ISO
IEA
IMP
(PMID:19342457)
GO_REF:0000107
RGD
Ensembl
PMID:19342457, PMID:19342457 GO_REF:0000107, RGD:4891166 NCBI chr14:33,131,985...33,152,019
Ensembl chr14:33,134,511...33,164,141
JBrowse link
negative regulation of fatty acid beta-oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (MGI:3530688|PMID:15677334), (MGI:3629477|PMID:12920182) RGD PMID:12920182 PMID:15677334 MGI:3530688 MGI:3629477 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Akt1 AKT serine/threonine kinase 1 involved_in ISO (PMID:16814735) RGD PMID:16814735 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Cnr1 cannabinoid receptor 1 IMP RGD PMID:19724020 RGD:2314644 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein IDA RGD PMID:11485163 RGD:2316274 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Mfsd2a major facilitator superfamily domain containing 2A acts_upstream_of_or_within ISO (MGI:5474727|PMID:23209793) RGD PMID:23209793 MGI:5474727 NCBI chr 5:140,642,865...140,657,759
Ensembl chr 5:140,642,885...140,657,745
JBrowse link
G Plin5 perilipin 5 involved_in ISS
ISO
GO_REF:0000024
(MGI:5440401|PMID:22532565), (MGI:5559662|PMID:22675471), (MGI:5559666|PMID:21885430)
UniProt
RGD
PMID:21885430 PMID:22532565 PMID:22675471 GO_REF:0000024 MGI:5440401 MGI:5559662 MGI:5559666 NCBI chr 9:10,956,013...10,961,782
Ensembl chr 9:10,956,056...10,961,782
JBrowse link
negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Etfbkmt electron transfer flavoprotein subunit beta lysine methyltransferase involved_in ISO
ISS
(PMID:25416781)
(MGI:5700285|PMID:25023281)
GO_REF:0000024
RGD
UniProt
PMID:25023281 PMID:25416781 GO_REF:0000024 MGI:5700285 NCBI chr 4:183,655,968...183,665,757
Ensembl chr 4:183,656,013...183,665,754
JBrowse link
negative regulation of fatty acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:3526480 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO
GO_REF:0000107
(MGI:3526480|PMID:15639194)
Ensembl
RGD
PMID:15639194 GO_REF:0000107 MGI:3526480 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Apoc1 apolipoprotein C1 involved_in ISO (PMID:15576844) RGD PMID:15576844 NCBI chr 1:80,606,638...80,609,921
Ensembl chr 1:80,606,638...80,609,921
JBrowse link
G Apoc3 apolipoprotein C3 involved_in ISO
IEA
(PMID:11060345), (PMID:18635818)
GO_REF:0000107
RGD
Ensembl
PMID:11060345 PMID:18635818 GO_REF:0000107 NCBI chr 8:50,529,318...50,531,498
Ensembl chr 8:50,529,318...50,531,498
JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISO
IEA
ISS
IBA
(PMID:16326698)
GO_REF:0000107
GO_REF:0000024
PMID:21873635
RGD
Ensembl
UniProt
PMID:16326698, PMID:21873635 GO_REF:0000024 GO_REF:0000107, RGD:13792537 NCBI chr10:89,394,821...89,455,093
Ensembl chr10:89,394,803...89,454,681
JBrowse link
G Ceacam1 CEA cell adhesion molecule 1 involved_in IMP PMID:16054098 UniProt PMID:16054098 RGD:11059593 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
G Cyp7a1 cytochrome P450 family 7 subfamily A member 1 involved_in IDA PMID:23536474 BHF-UCL PMID:23536474 RGD:13792517 NCBI chr 5:19,358,734...19,368,431
Ensembl chr 5:19,358,734...19,368,431
JBrowse link
G Erlin1 ER lipid raft associated 1 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr 1:263,810,439...263,845,762
Ensembl chr 1:263,810,439...263,845,762
JBrowse link
G Erlin2 ER lipid raft associated 2 involved_in ISO (PMID:24217618) RGD PMID:24217618 NCBI chr16:69,179,005...69,195,452
Ensembl chr16:69,179,588...69,195,097
JBrowse link
G Insig1 insulin induced gene 1 acts_upstream_of_or_within ISO MGI:1920249 (MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:3603108 NCBI chr 4:342,302...350,515
Ensembl chr 4:342,302...350,515
JBrowse link
G Insig2 insulin induced gene 2 acts_upstream_of_or_within ISO MGI:1916289 (MGI:3603108|PMID:16100574) RGD PMID:16100574 MGI:3603108 NCBI chr13:37,264,818...37,292,718
Ensembl chr13:37,266,312...37,287,458
JBrowse link
G Trib3 tribbles pseudokinase 3 involved_in ISO (MGI:3630230|PMID:16794074) RGD PMID:16794074 MGI:3630230 NCBI chr 3:147,814,056...147,819,650
Ensembl chr 3:147,813,473...147,819,571
JBrowse link
G Wdtc1 WD and tetratricopeptide repeats 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:3770497|PMID:17767906)
RGD PMID:17767906, PMID:21873635 MGI:3770497, RGD:13792537 NCBI chr 5:151,487,572...151,536,829
Ensembl chr 5:151,487,577...151,536,518
JBrowse link
negative regulation of fatty acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ins2 insulin 2 involved_in ISO (PMID:1184755) RGD PMID:1184755 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G LOC685081 similar to solute carrier family 22 (organic cation transporter), member 13 involved_in ISO (PMID:24769897)
(MGI:6212098|PMID:24769897)
RGD PMID:24769897 MGI:6212098 NCBI chr 8:127,905,478...127,914,897
Ensembl chr 8:127,909,147...127,912,860
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in ISO
IEA
(PMID:19955185)
GO_REF:0000107
RGD
Ensembl
PMID:19955185 GO_REF:0000107 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Ugt1a8 UDP glucuronosyltransferase family 1 member A8 involved_in ISO (PMID:20610558) RGD PMID:20610558 NCBI chr 9:95,221,474...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
G Ugt1a9 UDP glucuronosyltransferase family 1 member A9 involved_in ISO (PMID:20610558) RGD PMID:20610558 NCBI chr 9:95,161,157...95,302,822
Ensembl chr 9:95,161,157...95,302,822
JBrowse link
negative regulation of fatty acid oxidation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta involved_in ISO (MGI:1932690|PMID:11283375), (MGI:3804564|PMID:18487439) RGD PMID:11283375 PMID:18487439 MGI:1932690 MGI:3804564 NCBI chr12:48,127,149...48,238,969
Ensembl chr12:48,127,149...48,238,887
JBrowse link
G Acadl acyl-CoA dehydrogenase, long chain involved_in ISO (MGI:3526480|PMID:15639194) RGD PMID:15639194 MGI:3526480 NCBI chr 9:73,833,368...73,871,857
Ensembl chr 9:73,833,388...73,871,888
JBrowse link
G Acadvl acyl-CoA dehydrogenase, very long chain involved_in IEA
ISO
GO_REF:0000107
(MGI:3526480|PMID:15639194)
Ensembl
RGD
PMID:15639194 GO_REF:0000107 MGI:3526480 NCBI chr10:56,619,321...56,624,468
Ensembl chr10:56,619,303...56,624,526
JBrowse link
G Appl2 adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2 involved_in ISO (MGI:4420367|PMID:19661063) RGD PMID:19661063 MGI:4420367 NCBI chr 7:26,256,179...26,306,128
Ensembl chr 7:26,256,459...26,306,126
JBrowse link
G Dgat2 diacylglycerol O-acyltransferase 2 IMP RGD PMID:17526931 RGD:10400884 NCBI chr 1:164,113,459...164,143,818
Ensembl chr 1:164,113,459...164,143,818
JBrowse link
G Mir199a2 microRNA 199a-2 acts_upstream_of_or_within ISO (MGI:5528778|PMID:24011070) RGD PMID:24011070 MGI:5528778 NCBI chr13:80,125,487...80,125,596
Ensembl chr13:80,125,487...80,125,596
JBrowse link
G Sirt4 sirtuin 4 involved_in ISO (PMID:24043310)
(MGI:5501374|PMID:23746352), (MGI:5547879|PMID:24043310)
RGD PMID:23746352 PMID:24043310 MGI:5501374 MGI:5547879 NCBI chr12:46,862,358...46,876,593
Ensembl chr12:46,868,416...46,876,592
JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO
GO_REF:0000024
(MGI:6414737|PMID:32103177)
UniProt
RGD
PMID:32103177 GO_REF:0000024 MGI:6414737 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
negative regulation of gluconeogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adipoq adiponectin, C1Q and collagen domain containing involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:3055866|PMID:11479628)
UniProt
RGD
PMID:11479628 GO_REF:0000024 MGI:3055866 NCBI chr11:81,330,845...81,344,488
Ensembl chr11:81,330,293...81,344,488
JBrowse link
G C1qtnf12 C1q and TNF related 12 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:5317500|PMID:22275362)
RGD PMID:22275362, PMID:21873635 MGI:5317500, RGD:13792537 NCBI chr 5:173,390,901...173,395,276
Ensembl chr 5:173,390,901...173,395,276
JBrowse link
G C1qtnf3 C1q and TNF related 3 involved_in
acts_upstream_of_or_within
ISO (PMID:20952387)
(MGI:4868567|PMID:20952387)
RGD PMID:20952387 MGI:4868567 NCBI chr 2:60,920,160...60,942,586
Ensembl chr 2:60,920,257...60,942,500
JBrowse link
G Clk2 CDC-like kinase 2 involved_in ISO (MGI:4429735|PMID:20074525) RGD PMID:20074525 MGI:4429735 NCBI chr 2:188,476,789...188,488,809
Ensembl chr 2:188,476,820...188,496,191
JBrowse link
G Cry1 cryptochrome circadian regulator 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:5914352|PMID:28790135), (MGI:6208175|PMID:29937374)
UniProt
RGD
PMID:28790135 PMID:29937374 GO_REF:0000024 MGI:5914352 MGI:6208175 NCBI chr 7:24,534,593...24,634,098
Ensembl chr 7:24,534,615...24,634,097
JBrowse link
G Ep300 E1A binding protein p300 involved_in ISO (PMID:30193097) RGD PMID:30193097 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Erfe erythroferrone involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:98,505,136...98,513,005
Ensembl chr 9:98,505,259...98,511,160
JBrowse link
G Fam3a FAM3 metabolism regulating signaling molecule A involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:156,319,687...156,328,974
Ensembl chr  X:156,319,687...156,328,309
JBrowse link
G Fam3c FAM3 metabolism regulating signaling molecule C involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 4:49,388,962...49,439,892
Ensembl chr 4:49,387,989...49,439,867
JBrowse link
G Gck glucokinase involved_in ISO
IEA
ISS
(PMID:8878425)
GO_REF:0000107
GO_REF:0000024
RGD
Ensembl
UniProt
PMID:8878425 GO_REF:0000024 GO_REF:0000107 NCBI chr14:86,149,146...86,191,589
Ensembl chr14:86,148,928...86,190,659
JBrowse link
G Il6 interleukin 6 IDA In liver RGD PMID:16308834 RGD:2306940 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 involved_in ISO (PMID:8069456) RGD PMID:8069456 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Lepr leptin receptor acts_upstream_of_or_within ISO MGI:1856009 (MGI:5529403|PMID:24051374) RGD PMID:24051374 MGI:5529403 NCBI chr 5:120,503,475...120,682,281
Ensembl chr 5:120,564,645...120,682,221
JBrowse link
G LOC259246 alpha-2u globulin PGCL1 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 Ensembl chr 5:77,338,853...77,342,299
Ensembl chr 5:77,338,853...77,342,299
JBrowse link
G Maea macrophage erythroblast attacher, E3 ubiquitin ligase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr14:82,664,248...82,697,673
Ensembl chr14:82,664,249...82,697,673
JBrowse link
G Mst1 macrophage stimulating 1 involved_in ISO (PMID:19720831) RGD PMID:19720831 NCBI chr 8:116,857,716...116,862,286
Ensembl chr 8:116,857,684...116,862,423
JBrowse link
G Obp2a odorant binding protein 2A acts_upstream_of_or_within ISO MGI:2137691 (MGI:4946468|PMID:21135134) RGD PMID:21135134 MGI:4946468 NCBI chr 3:2,908,684...2,913,362
Ensembl chr 3:2,910,083...2,913,362
JBrowse link
G Pgp phosphoglycolate phosphatase involved_in IMP
ISO
PMID:26755581
(PMID:26755581)
RGD PMID:26755581, PMID:26755581 RGD:10679995 NCBI chr10:13,836,105...13,838,731
Ensembl chr10:13,836,128...13,838,765
JBrowse link
G Serpina12 serpin family A member 12 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:5563627|PMID:22837305)
Ensembl
RGD
PMID:22837305 GO_REF:0000107 MGI:5563627 NCBI chr 6:127,696,501...127,711,238
Ensembl chr 6:127,696,252...127,711,212
JBrowse link
G Sik1 salt-inducible kinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:3606826|PMID:16148943)
UniProt
RGD
PMID:16148943 GO_REF:0000024 MGI:3606826 NCBI chr20:10,670,747...10,680,279
Ensembl chr20:10,668,411...10,680,283
JBrowse link
G Soga1 suppressor of glucose, autophagy associated 1 involved_in ISO (MGI:4837302|PMID:20813965) RGD PMID:20813965 MGI:4837302 NCBI chr 3:153,130,268...153,188,909
Ensembl chr 3:153,125,620...153,188,915
JBrowse link
negative regulation of glucose catabolic process to lactate via pyruvate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:57,881,951...57,998,214
Ensembl chr 3:57,882,370...57,957,346
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
negative regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atcay ATCAY kinesin light chain interacting caytaxin involved_in ISO
ISS
(PMID:16899818)
GO_REF:0000024
RGD
UniProt
PMID:16899818 GO_REF:0000024 NCBI chr 7:11,356,017...11,379,782
Ensembl chr 7:11,356,118...11,380,913
JBrowse link
negative regulation of glycolytic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) RGD PMID:17828264 MGI:3759354 NCBI chr 1:220,120,532...220,136,460
Ensembl chr 1:220,120,533...220,136,470
JBrowse link
G Cbfa2t3 CBFA2/RUNX1 partner transcriptional co-repressor 3 involved_in ISO (PMID:23840896) RGD PMID:23840896 NCBI chr19:55,438,409...55,510,652
Ensembl chr19:55,441,572...55,510,460
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:4440406|PMID:20176937)
Ensembl
RGD
PMID:20176937 GO_REF:0000107 MGI:4440406 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Fbp1 fructose-bisphosphatase 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:19881551), (PMID:25043030)
UniProt
Ensembl
RGD
PMID:19881551 PMID:25043030 GO_REF:0000024 GO_REF:0000107 NCBI chr17:396,175...417,480
Ensembl chr17:396,180...417,480
JBrowse link
G Git1 GIT ArfGAP 1 involved_in ISS
ISO
IEA
GO_REF:0000024
(MGI:6478067|PMID:32460388)
GO_REF:0000107
UniProt
RGD
Ensembl
PMID:32460388 GO_REF:0000024 GO_REF:0000107 MGI:6478067 NCBI chr10:62,656,000...62,664,467
Ensembl chr10:62,656,000...62,664,466
JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO (MGI:4365327|PMID:19109424) RGD PMID:19109424 MGI:4365327 NCBI chr 9:99,052,945...99,299,715
Ensembl chr 9:99,057,089...99,299,715
JBrowse link
G Ier3 immediate early response 3 acts_upstream_of_or_within ISO MGI:3773690 (MGI:4437986|PMID:19096392) RGD PMID:19096392 MGI:4437986 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Mtch2 mitochondrial carrier 2 acts_upstream_of_or_within ISO MGI:2449949|MGI:5566664 (MGI:5662300|PMID:26219591) RGD PMID:26219591 MGI:5662300 NCBI chr 3:79,678,141...79,695,356
Ensembl chr 3:79,678,201...79,694,006
JBrowse link
G Myog myogenin IDA RGD PMID:10225962 RGD:9686132 NCBI chr13:51,126,459...51,129,048
Ensembl chr13:51,126,459...51,129,048
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 involved_in IEA
ISO
GO_REF:0000107
(PMID:19955185)
Ensembl
RGD
PMID:19955185 GO_REF:0000107 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Nupr1 nuclear protein 1, transcriptional regulator involved_in ISO
ISS
(PMID:30451898)
GO_REF:0000024
RGD
UniProt
PMID:30451898 GO_REF:0000024 NCBI chr 1:194,767,484...194,769,519
Ensembl chr 1:194,767,474...194,769,524
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha involved_in ISO (PMID:19955185) RGD PMID:19955185 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IMP RGD PMID:22343369 RGD:7242186 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Sirt6 sirtuin 6 involved_in ISO (MGI:4881401|PMID:20141841), (MGI:5619441|PMID:23217706) RGD PMID:20141841 PMID:23217706 MGI:4881401 MGI:5619441 NCBI chr 7:10,937,622...10,943,048
Ensembl chr 7:10,937,599...10,943,063
JBrowse link
G Stat3 signal transducer and activator of transcription 3 acts_upstream_of_or_within ISO (MGI:5441121|PMID:22891351) RGD PMID:22891351 MGI:5441121 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link
G Tigar TP53 induced glycolysis regulatory phosphatase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(MGI:4867601|PMID:20935145)
RGD PMID:20935145, PMID:21873635 MGI:4867601, RGD:13792537 NCBI chr 4:159,635,145...159,654,108
Ensembl chr 4:159,635,153...159,654,063
JBrowse link
negative regulation of glycolytic process through fructose-6-phosphate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Slc4a1 solute carrier family 4 member 1 (Diego blood group) involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:3820439|PMID:18698006)
Ensembl
RGD
PMID:18698006 GO_REF:0000107 MGI:3820439 NCBI chr10:90,296,144...90,312,401
Ensembl chr10:90,296,141...90,312,386
JBrowse link
negative regulation of guanylate cyclase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hpca hippocalcin IDA RGD PMID:15336960 RGD:9686438 NCBI chr 5:147,295,124...147,305,757
Ensembl chr 5:147,294,820...147,303,346
JBrowse link
G Pdzd3 PDZ domain containing 3 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 8:48,577,905...48,582,353
Ensembl chr 8:48,577,952...48,582,353
JBrowse link
G Rd3 RD3 regulator of GUCY2D involved_in ISO (PMID:21928830), (PMID:30559291)
(MGI:5810226|PMID:27471269)
RGD PMID:21928830 PMID:27471269 PMID:30559291 MGI:5810226 NCBI chr13:110,739,645...110,749,167
Ensembl chr13:110,743,098...110,748,365
JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin involved_in ISO (PMID:7559487), (PMID:7782310) RGD PMID:7559487 PMID:7782310 NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:7535379 RGD:7777104 NCBI chr 1:248,982,039...250,300,952 JBrowse link
negative regulation of nucleotide metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cda cytidine deaminase involved_in ISO (PMID:9596658) RGD PMID:9596658 NCBI chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541
Ensembl chr 5:156,703,579...156,734,541
JBrowse link
negative regulation of prostaglandin biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pibf1 progesterone immunomodulatory binding factor 1 involved_in ISO (PMID:3863495) RGD PMID:3863495 NCBI chr15:83,494,110...83,663,202
Ensembl chr15:83,495,377...83,663,143
JBrowse link
G Sirt1 sirtuin 1 involved_in ISO (MGI:5306564|PMID:20042607) RGD PMID:20042607 MGI:5306564 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000104
(PMID:12140278)
UniProt
RGD
PMID:12140278 GO_REF:0000024 GO_REF:0000104 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
negative regulation of retinoic acid biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akr1c3 aldo-keto reductase family 1, member C3 involved_in ISO (PMID:21851338) RGD PMID:21851338 NCBI chr17:69,761,126...69,778,021
Ensembl chr17:69,761,118...69,778,021
JBrowse link
negative regulation of testosterone biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkkl1 dickkopf like acrosomal protein 1 involved_in ISO (MGI:3839065|PMID:18818293) RGD PMID:18818293 MGI:3839065 NCBI chr 1:101,205,426...101,210,675
Ensembl chr 1:101,205,426...101,210,675
JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO
IEA
(PMID:12949260)
(MGI:2675528|PMID:12949260)
GO_REF:0000107
RGD
Ensembl
PMID:12949260 GO_REF:0000107 MGI:2675528 NCBI chr 5:155,649,238...155,668,065
Ensembl chr 5:155,649,217...155,672,579
JBrowse link
negative regulation of vitamin D biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Snai1 snail family transcriptional repressor 1 involved_in ISO (PMID:19502595) RGD PMID:19502595 NCBI chr 3:164,274,710...164,279,199
Ensembl chr 3:164,274,710...164,279,378
JBrowse link
G Snai2 snail family transcriptional repressor 2 involved_in ISO (PMID:18485278), (PMID:19502595) RGD PMID:18485278 PMID:19502595 NCBI chr11:90,404,421...90,406,730
Ensembl chr11:90,403,333...90,406,797
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19638
    metabolic process 11894
      negative regulation of metabolic process 3194
        negative regulation of small molecule metabolic process 103
          negative regulation of (R)-mevalonic acid biosynthetic process 0
          negative regulation of UDP-N-acetylglucosamine biosynthetic process 0
          negative regulation of UDP-glucose catabolic process 0
          negative regulation of acetate catabolic process 0
          negative regulation of aflatoxin biosynthetic process 0
          negative regulation of alcohol biosynthetic process + 14
          negative regulation of aldosterone metabolic process + 4
          negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity 1
          negative regulation of androst-4-ene-3,17-dione biosynthetic process 0
          negative regulation of asperthecin biosynthetic process 0
          negative regulation of bile acid metabolic process + 3
          negative regulation of cellular alcohol catabolic process 0
          negative regulation of cellular amino acid metabolic process + 2
          negative regulation of cellular glucuronidation 3
          negative regulation of cholesterol metabolic process + 5
          negative regulation of cordyol C biosynthetic process 0
          negative regulation of diorcinol biosynthetic process 0
          negative regulation of ecdysteroid metabolic process + 0
          negative regulation of emodin biosynthetic process 0
          negative regulation of endocrocin biosynthetic process 0
          negative regulation of fatty acid metabolic process + 32
          negative regulation of ferulate catabolic process 0
          negative regulation of fumagillin biosynthetic process 0
          negative regulation of fumonisin biosynthetic process 0
          negative regulation of gerfelin biosynthetic process 0
          negative regulation of gibberellin biosynthetic process 0
          negative regulation of gluconeogenesis 21
          negative regulation of glucose catabolic process to lactate via pyruvate 3
          negative regulation of glyoxylate cycle 0
          negative regulation of helvolic acid biosynthetic process 0
          negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway 0
          negative regulation of methane biosynthetic process from formic acid 0
          negative regulation of methyl-branched fatty acid biosynthetic process 0
          negative regulation of monodictyphenone biosynthetic process 0
          negative regulation of naphtho-gamma-pyrone biosynthetic process 0
          negative regulation of nucleoside metabolic process 0
          negative regulation of nucleotide metabolic process + 25
          negative regulation of o-orsellinic acid biosynthetic process 0
          negative regulation of penicillin metabolic process + 0
          negative regulation of progesterone biosynthetic process + 0
          negative regulation of purine nucleobase metabolic process 0
          negative regulation of pyrimidine nucleobase metabolic process 0
          negative regulation of quinolinate biosynthetic process 1
          negative regulation of sarcinapterin metabolic process + 0
          negative regulation of sulfur amino acid metabolic process + 0
          negative regulation of tatiopterin metabolic process + 0
          negative regulation of tensidol A biosynthetic process 0
          negative regulation of tensidol B biosynthetic process 0
          negative regulation of terrequinone A biosynthetic process 0
          negative regulation of testosterone biosynthetic process 2
          negative regulation of ubiquinone biosynthetic process 0
          negative regulation of urea catabolic process 0
          negative regulation of violaceol I biosynthetic process 0
          negative regulation of violaceol II biosynthetic process 0
          negative regulation of vitamin metabolic process + 6
          negative regulation of xanthone-containing compound biosynthetic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19638
    biological regulation 13583
      regulation of biological process 12829
        regulation of metabolic process 6789
          regulation of small molecule metabolic process 370
            negative regulation of small molecule metabolic process 103
              negative regulation of (R)-mevalonic acid biosynthetic process 0
              negative regulation of UDP-N-acetylglucosamine biosynthetic process 0
              negative regulation of UDP-glucose catabolic process 0
              negative regulation of acetate catabolic process 0
              negative regulation of aflatoxin biosynthetic process 0
              negative regulation of alcohol biosynthetic process + 14
              negative regulation of aldosterone metabolic process + 4
              negative regulation of all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity 1
              negative regulation of androst-4-ene-3,17-dione biosynthetic process 0
              negative regulation of asperthecin biosynthetic process 0
              negative regulation of bile acid metabolic process + 3
              negative regulation of cellular alcohol catabolic process 0
              negative regulation of cellular amino acid metabolic process + 2
              negative regulation of cellular glucuronidation 3
              negative regulation of cholesterol metabolic process + 5
              negative regulation of cordyol C biosynthetic process 0
              negative regulation of diorcinol biosynthetic process 0
              negative regulation of ecdysteroid metabolic process + 0
              negative regulation of emodin biosynthetic process 0
              negative regulation of endocrocin biosynthetic process 0
              negative regulation of fatty acid metabolic process + 32
              negative regulation of ferulate catabolic process 0
              negative regulation of fumagillin biosynthetic process 0
              negative regulation of fumonisin biosynthetic process 0
              negative regulation of gerfelin biosynthetic process 0
              negative regulation of gibberellin biosynthetic process 0
              negative regulation of gluconeogenesis 21
              negative regulation of glucose catabolic process to lactate via pyruvate 3
              negative regulation of glyoxylate cycle 0
              negative regulation of helvolic acid biosynthetic process 0
              negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway 0
              negative regulation of methane biosynthetic process from formic acid 0
              negative regulation of methyl-branched fatty acid biosynthetic process 0
              negative regulation of monodictyphenone biosynthetic process 0
              negative regulation of naphtho-gamma-pyrone biosynthetic process 0
              negative regulation of nucleoside metabolic process 0
              negative regulation of nucleotide metabolic process + 25
              negative regulation of o-orsellinic acid biosynthetic process 0
              negative regulation of penicillin metabolic process + 0
              negative regulation of progesterone biosynthetic process + 0
              negative regulation of purine nucleobase metabolic process 0
              negative regulation of pyrimidine nucleobase metabolic process 0
              negative regulation of quinolinate biosynthetic process 1
              negative regulation of sarcinapterin metabolic process + 0
              negative regulation of sulfur amino acid metabolic process + 0
              negative regulation of tatiopterin metabolic process + 0
              negative regulation of tensidol A biosynthetic process 0
              negative regulation of tensidol B biosynthetic process 0
              negative regulation of terrequinone A biosynthetic process 0
              negative regulation of testosterone biosynthetic process 2
              negative regulation of ubiquinone biosynthetic process 0
              negative regulation of urea catabolic process 0
              negative regulation of violaceol I biosynthetic process 0
              negative regulation of violaceol II biosynthetic process 0
              negative regulation of vitamin metabolic process + 6
              negative regulation of xanthone-containing compound biosynthetic process + 0
paths to the root